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The map label for this gene is Qri7

Identifier: 161760536

GI number: 161760536

Start: 544025

End: 545050

Strand: Direct

Name: Qri7

Synonym: TTE0538

Alternate gene names: 161760536

Gene position: 544025-545050 (Clockwise)

Preceding gene: 20807038

Following gene: 20807040

Centisome position: 20.23

GC content: 41.91

Gene sequence:

>1026_bases
ATGGCGAAAGACATTGTAATTTTAGGAATAGAGACTTCCTGCGATGAAACGGCTGCGGGGGTTGTGAAAAACGGAAAAGA
AGTGCTTTCAAATGTCATATACTCTCAAATAAATGTGCACAAAAAGTACGGCGGTGTGGTGCCTGAAATTGCATCAAGAA
AGCACATTGAAGCGATTTCATTTGTGGTAGAAGAAGCGCTCAATGAGGCGAAGCTAAGTCTTGATGAAGTGGATGCAATA
GCCGCTACATACGGGCCAGGGCTTGTAGGCCCTCTTTTAGTTGGTTTATCTTACGGTAAAGCTTTAGCCTATGCTAAAGG
GAAACCTTTCATCGGAGTTAATCACATTGACGGGCACATTGCGGCAAATTATATAGGTGGTAATTTAACGCCGCCTTTTG
TTTGTCTTGTAGCATCTGGTGGACACAGCCATATAGTTTATGTGAAGGACTATGGGGAATATGAGGTAATGGGGAAAACT
TTGGATGATGCAGCTGGAGAAGCTTTTGATAAGGTGGCTAGGGCGTTGGGATTGGGATATCCCGGAGGTCCGGCTATTGA
AAAAGCTGCAAAGCTTGGGAATATGGAGGCGATCGAGTTTCCAAAGTCTTTTATGGAAGAAGGAAATTTTGATTTCAGTT
TTAGCGGGGTAAAGACTGCTGTTTTGAATTACCTCAACAGGCAGAAGCAAAAGGGAGAAGAAGTAAATATTTATGACGTT
GCCGCCAGCTTCCAGAGAAATATAGTGGAGGTTTTGGTGAAAAAATTGGTGGAGGCAGCGAGGTTTAAAAATGTCAGCAA
AGTTTCCATAGCAGGAGGTGTTGCTTCTAACGGCTTCTTAAGGCAAAAATTAGAAGAGGATGCGAAAAAGTTTGGGCTTT
CTGTCTATTATCCTGAAAAAATTTATTGCACAGACAACGGTGCAATGATAGCTGCAGCTGCCTATTACGATTTTGTAAAA
GGAAAATTTTCAGGGATGGATTTAAATGCCATTCCATATCTCAAAATTGGGGAAAGTGATTGTTAG

Upstream 100 bases:

>100_bases
AGTTCGGCTTTAAAGTTTTAGGCAGAAGGGAAGGATATTATCAGGATAACAATGAAGATGCTATAGTGATGTGGAAATAC
GATTTGTAGTGGTGGTGGAA

Downstream 100 bases:

>100_bases
AATTGGGGAAAACTGTCGATAAAACAGAAATTTTGAGTTTTTCTGTTTGTGGATAACTCTGTGGATATTGTGCTTAACTA
TATTTCATTTCATTTACTGG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAKDIVILGIETSCDETAAGVVKNGKEVLSNVIYSQINVHKKYGGVVPEIASRKHIEAISFVVEEALNEAKLSLDEVDAI
AATYGPGLVGPLLVGLSYGKALAYAKGKPFIGVNHIDGHIAANYIGGNLTPPFVCLVASGGHSHIVYVKDYGEYEVMGKT
LDDAAGEAFDKVARALGLGYPGGPAIEKAAKLGNMEAIEFPKSFMEEGNFDFSFSGVKTAVLNYLNRQKQKGEEVNIYDV
AASFQRNIVEVLVKKLVEAARFKNVSKVSIAGGVASNGFLRQKLEEDAKKFGLSVYYPEKIYCTDNGAMIAAAAYYDFVK
GKFSGMDLNAIPYLKIGESDC

Sequences:

>Translated_341_residues
MAKDIVILGIETSCDETAAGVVKNGKEVLSNVIYSQINVHKKYGGVVPEIASRKHIEAISFVVEEALNEAKLSLDEVDAI
AATYGPGLVGPLLVGLSYGKALAYAKGKPFIGVNHIDGHIAANYIGGNLTPPFVCLVASGGHSHIVYVKDYGEYEVMGKT
LDDAAGEAFDKVARALGLGYPGGPAIEKAAKLGNMEAIEFPKSFMEEGNFDFSFSGVKTAVLNYLNRQKQKGEEVNIYDV
AASFQRNIVEVLVKKLVEAARFKNVSKVSIAGGVASNGFLRQKLEEDAKKFGLSVYYPEKIYCTDNGAMIAAAAYYDFVK
GKFSGMDLNAIPYLKIGESDC
>Mature_340_residues
AKDIVILGIETSCDETAAGVVKNGKEVLSNVIYSQINVHKKYGGVVPEIASRKHIEAISFVVEEALNEAKLSLDEVDAIA
ATYGPGLVGPLLVGLSYGKALAYAKGKPFIGVNHIDGHIAANYIGGNLTPPFVCLVASGGHSHIVYVKDYGEYEVMGKTL
DDAAGEAFDKVARALGLGYPGGPAIEKAAKLGNMEAIEFPKSFMEEGNFDFSFSGVKTAVLNYLNRQKQKGEEVNIYDVA
ASFQRNIVEVLVKKLVEAARFKNVSKVSIAGGVASNGFLRQKLEEDAKKFGLSVYYPEKIYCTDNGAMIAAAAYYDFVKG
KFSGMDLNAIPYLKIGESDC

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=327, Percent_Identity=36.085626911315, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI8923380, Length=317, Percent_Identity=31.2302839116719, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1789445, Length=333, Percent_Identity=41.7417417417417, Blast_Score=266, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17557464, Length=321, Percent_Identity=30.2180685358255, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=324, Percent_Identity=29.9382716049383, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=340, Percent_Identity=31.7647058823529, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=352, Percent_Identity=27.5568181818182, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=33.5276967930029, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=32.8267477203647, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_THETN (Q8RC98)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622210.2
- ProteinModelPortal:   Q8RC98
- SMR:   Q8RC98
- MEROPS:   M22.001
- GeneID:   996227
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0538
- NMPDR:   fig|273068.3.peg.1056
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   TTEN273068:TTE0538-MONOMER
- BRENDA:   3.4.24.57
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36577; Mature: 36446

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01016 GLYCOPROTEASE; PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDIVILGIETSCDETAAGVVKNGKEVLSNVIYSQINVHKKYGGVVPEIASRKHIEAIS
CCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHH
FVVEEALNEAKLSLDEVDAIAATYGPGLVGPLLVGLSYGKALAYAKGKPFIGVNHIDGHI
HHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCEEEECCCCEE
AANYIGGNLTPPFVCLVASGGHSHIVYVKDYGEYEVMGKTLDDAAGEAFDKVARALGLGY
EEEECCCCCCCCEEEEEECCCCCEEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCCCC
PGGPAIEKAAKLGNMEAIEFPKSFMEEGNFDFSFSGVKTAVLNYLNRQKQKGEEVNIYDV
CCCHHHHHHHHHCCCHHHHCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEHH
AASFQRNIVEVLVKKLVEAARFKNVSKVSIAGGVASNGFLRQKLEEDAKKFGLSVYYPEK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCE
IYCTDNGAMIAAAAYYDFVKGKFSGMDLNAIPYLKIGESDC
EEECCCCCEEEHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure 
AKDIVILGIETSCDETAAGVVKNGKEVLSNVIYSQINVHKKYGGVVPEIASRKHIEAIS
CCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHH
FVVEEALNEAKLSLDEVDAIAATYGPGLVGPLLVGLSYGKALAYAKGKPFIGVNHIDGHI
HHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCEEEECCCCEE
AANYIGGNLTPPFVCLVASGGHSHIVYVKDYGEYEVMGKTLDDAAGEAFDKVARALGLGY
EEEECCCCCCCCEEEEEECCCCCEEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCCCC
PGGPAIEKAAKLGNMEAIEFPKSFMEEGNFDFSFSGVKTAVLNYLNRQKQKGEEVNIYDV
CCCHHHHHHHHHCCCHHHHCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEHH
AASFQRNIVEVLVKKLVEAARFKNVSKVSIAGGVASNGFLRQKLEEDAKKFGLSVYYPEK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCE
IYCTDNGAMIAAAAYYDFVKGKFSGMDLNAIPYLKIGESDC
EEECCCCCEEEHHHHHHHHCCCCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336