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The map label for this gene is ileS

Identifier: 161751096

GI number: 161751096

Start: 436977

End: 440120

Strand: Reverse

Name: ileS

Synonym: ST0431

Alternate gene names: 161751096

Gene position: 440120-436977 (Counterclockwise)

Preceding gene: 15920644

Following gene: 15920642

Centisome position: 16.33

GC content: 33.21

Gene sequence:

>3144_bases
TTGCCATCTAAATTTGATCCTCTTTCTACAGAAAAAGAAATATTAAAGTTTTGGGAGCAAAATAAAATCTATGAAAAATT
AAAAGAATATAACAGTAAATTTGAGAAAAAATTCCTATTTATAGATGGGCCACCTTATCCTTCAAGCCCAATCCCACATA
TAGGAACCGTTTGGAATAAGGTAATAAAGGATTGTATACTAAGATATGAAAGGTTAGCAGGATTTAGGACCTATGATCAG
CCTGGTTATGATACTCATGGTTTGCCTATAGAAGTTGCAATAGAAAAACAACTTGGAATACAAAAGAAATCGGATATAAT
AGAAAAAATAGGAGTTGATAATTTTGTTAATAAGTGTAAGGAATTTGCATTAAATAACGCATCTTCTTTGACTGCAAACT
TTAAGAACATAGGAATTTTTATGGACTGGAACAACCCCTATATGACATTACATAATGACTATATTTCTAACTCTTGGATG
CTAATCAAGAAAGCATATGAAAGAGGATTATTATATAAAGGAGTACATGTTTTACATTGGTGCCCTAGATGCGAAACAAC
ATTAGCTGATTATGAGGTTTCAGAATATAAAGAAATTGAAGACCCATCAATTTATGTGAAATTTAAAGTAAAAGGCTCAG
AAAATAGGTATTTAGTTATTTGGACTACAACACCATGGACTTTACCGGCAAATGTCTTTGTTATGATTAATAAAGATTAT
GAGTATGCTGAAGTCGAGGTCAATAATGAGATACTAATTATGGCAAAAGATAGAGTAAGTGATGTTATGAAAGAAGCAGG
AATTAAAAACTATAAGATAGTAAGGACATTTAAAGGAGTGGAATTAGTTGGATTACAATATATACACCCTTTGGCAGATA
TAGTCACAGCTCAGAAAGGGCTTGACAATTATCATATAGTCGTTGATGCTGGAGAAGAAGTAACGTTAACTGAGGGAACG
GGTCTTGTTCATTCTGCTCCAGGTCATGGTGATATTGACTTTGAAATAGGCAAAAAAATTGGAGCACCAGTAGTTATGTT
AGTTAATGATAGAGGTGAATTCTTACCAGAAGCTGGAAAATATGTTGGAAAAAATGTACGAAGTGCCGCTGAAGAAATTA
TTAATGACTTAAAACAGAGAAATGCCTTACTGCATTCTGGCAAGGTTGTCCATAGATATCCTGTATGTTGGAGATGTAAA
ACACCTCTAATTTTGAGGGCTATAGAGCAATGGTTTATAGGAGTATCTAAACTAAAAGAGGAATTGTTAAAAGAGATTGA
CAATGTTAAATGGGTACCTGACTGGGGTAAGACAAGAATAGGAAATATGGTAAGAGAGATTAGGGATTGGGTAATTAGCA
GACAGAGATTTTGGGGAACACCATTACCAATATGGATATGTAAGAATTGTGGAAACATAATTGTTATAGGAAGTAGAGAT
GAGTTAGAAAAAGTAGCAATAACAAAAGTACCAGAGGATTTACATAGACCATGGATAGATAAAGTAGTTGTCCGATGTAA
TAAATGTGGAGGAGAAGCTCATAGAGTTCCAGATGTGGCTGATGTGTGGTTTGATAGTGGGGTAGCTTTCTTCGCTAGCC
TAGGTAAAGATTGGGAAAAAAAGTGGAAAGAAATAGGTCCCGTTGATTTAGTATTAGAGGGACACGATCAATTACGAGGA
TGGTTCTTTAGCCTACTAAGGGCTGGTGTTATATTATTAGATAGAGCACCATATAATGCAGTTCTAGTCCATGGGTTTAT
GTTAGATGAACAAGGTAGAGAAATGCATAAGAGTCTTGGAAATTATGTAGAGCCATCTCAAGTAACTGAAAATGAAAAAT
ATGGTAGAGATGTCTTGAGATTATGGTTACTCAGAAATACAACATGGGAAGATGCAAAGTTCTCTTGGAAAGCACTTGAT
CAAACAAAAAGAGATTTAAACATTATATGGAATGTGTATGTTTTCGCATCAACATATATGAACTTAGACAACTTCGATCC
AAGAATATATAACCTAGACAACTTAAAACAATACCTGAGGATAGAAGATTTATGGTTATTATCTAGATATAATAGAGTTG
TAAAAGAAGTAAAGGAAAGCATGAACGATTTCAAAGTCCATGAGTTAGCAAATAAAATGACAAGTTTCATCATAGATGAT
ATAAGTAGGTTCTATCTAAGATTAGTCAGAAAAAGAGCTTGGAACGAAAGTAATGACCCAGATAAGATAGCAATGTATTA
TGTACTTTATGAAGTTCTCAAGGGATCACTAGTACTTTTATCCCCGGTAATTCCGTTTACTACTGAACGAATATACCAGG
ATTTTGTAGTAGATAAGAAGGATTCTGTTAGCATGGAAAGCTTACCAGAAGTAAAAGAAGAATTCATAAATGATAAAATT
GAGAAAGAATTTGAACTAAGCAAAGAGATTGCAGAAGCTGGATTAAATGCTAGAGCCAAGGCTGGAATTAAATTAAGATG
GCCAATAAAGAACGCATATGTATTTCTAGTCTCGGATATAGACGTTGAAATGGCCAATAATGTAAAAGAAGTAATAAAGT
TCTTATTAAATACTAAAGACGTAGAAATTGGAGGAATAGAAGGCTATAGAAGGTTTAGTAAAATTAAGGCCACACCAAAC
AGAGGTACAATTGGACCCGATTTCAAAAGGCTTACTAACAAAATAGTAGAATATATAGAAAATAACTCAGAAAAAGTAGC
TTCGGATATTATAGCTAAAGGTTACCATGAAGTTGTAATAGAAGGAGAACCAGTTCAAATCAAGGTTAATCATGTTAATA
TACTAGAAGAAACTGAAGAAGGTTACATATCTGCTAGGTTTAACAAGGGAGTAGTAGTTCTAAAGAAAGAAATAAGTAAA
GAAGAGGAAGAAGAAGGAATAGTTAGAGATATTATAAGAAGAATCCAGTTTATGAGAAAGCAACTTAATGTGCAAATTAA
TGATTATATTCTGTTGTATATAAAAGCACCAGAGGAAAGAACAGAAATGTTAAAGAAATGGACTGATTACATCAAATCAG
AGACTAGGGCTAAAGAAGTTATTATAGGAGAAGTAAAAGGAGACCTAATATTACCATGGGAAATAGAGGATGAAGAATAT
ATTATTGGTGTAAGTAAATCTTGA

Upstream 100 bases:

>100_bases
TAATAAATGAAATTTATAATAAGCTAGGCTAAAAGTTTTTAAATCACTACTTTATCTATTATCGAGGTGATCTAGATTAT
CCTCCCCTACAATAAAGCCT

Downstream 100 bases:

>100_bases
TGTTTCCTTATCCAAGAAGAAAAGAGTTAAACGTGATTCTTTTTACATCAATTTTTTCAACAGATAAAAGCTTAACCGAA
ATTACGTTAAAAATGTCCTT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1047; Mature: 1046

Protein sequence:

>1047_residues
MPSKFDPLSTEKEILKFWEQNKIYEKLKEYNSKFEKKFLFIDGPPYPSSPIPHIGTVWNKVIKDCILRYERLAGFRTYDQ
PGYDTHGLPIEVAIEKQLGIQKKSDIIEKIGVDNFVNKCKEFALNNASSLTANFKNIGIFMDWNNPYMTLHNDYISNSWM
LIKKAYERGLLYKGVHVLHWCPRCETTLADYEVSEYKEIEDPSIYVKFKVKGSENRYLVIWTTTPWTLPANVFVMINKDY
EYAEVEVNNEILIMAKDRVSDVMKEAGIKNYKIVRTFKGVELVGLQYIHPLADIVTAQKGLDNYHIVVDAGEEVTLTEGT
GLVHSAPGHGDIDFEIGKKIGAPVVMLVNDRGEFLPEAGKYVGKNVRSAAEEIINDLKQRNALLHSGKVVHRYPVCWRCK
TPLILRAIEQWFIGVSKLKEELLKEIDNVKWVPDWGKTRIGNMVREIRDWVISRQRFWGTPLPIWICKNCGNIIVIGSRD
ELEKVAITKVPEDLHRPWIDKVVVRCNKCGGEAHRVPDVADVWFDSGVAFFASLGKDWEKKWKEIGPVDLVLEGHDQLRG
WFFSLLRAGVILLDRAPYNAVLVHGFMLDEQGREMHKSLGNYVEPSQVTENEKYGRDVLRLWLLRNTTWEDAKFSWKALD
QTKRDLNIIWNVYVFASTYMNLDNFDPRIYNLDNLKQYLRIEDLWLLSRYNRVVKEVKESMNDFKVHELANKMTSFIIDD
ISRFYLRLVRKRAWNESNDPDKIAMYYVLYEVLKGSLVLLSPVIPFTTERIYQDFVVDKKDSVSMESLPEVKEEFINDKI
EKEFELSKEIAEAGLNARAKAGIKLRWPIKNAYVFLVSDIDVEMANNVKEVIKFLLNTKDVEIGGIEGYRRFSKIKATPN
RGTIGPDFKRLTNKIVEYIENNSEKVASDIIAKGYHEVVIEGEPVQIKVNHVNILEETEEGYISARFNKGVVVLKKEISK
EEEEEGIVRDIIRRIQFMRKQLNVQINDYILLYIKAPEERTEMLKKWTDYIKSETRAKEVIIGEVKGDLILPWEIEDEEY
IIGVSKS

Sequences:

>Translated_1047_residues
MPSKFDPLSTEKEILKFWEQNKIYEKLKEYNSKFEKKFLFIDGPPYPSSPIPHIGTVWNKVIKDCILRYERLAGFRTYDQ
PGYDTHGLPIEVAIEKQLGIQKKSDIIEKIGVDNFVNKCKEFALNNASSLTANFKNIGIFMDWNNPYMTLHNDYISNSWM
LIKKAYERGLLYKGVHVLHWCPRCETTLADYEVSEYKEIEDPSIYVKFKVKGSENRYLVIWTTTPWTLPANVFVMINKDY
EYAEVEVNNEILIMAKDRVSDVMKEAGIKNYKIVRTFKGVELVGLQYIHPLADIVTAQKGLDNYHIVVDAGEEVTLTEGT
GLVHSAPGHGDIDFEIGKKIGAPVVMLVNDRGEFLPEAGKYVGKNVRSAAEEIINDLKQRNALLHSGKVVHRYPVCWRCK
TPLILRAIEQWFIGVSKLKEELLKEIDNVKWVPDWGKTRIGNMVREIRDWVISRQRFWGTPLPIWICKNCGNIIVIGSRD
ELEKVAITKVPEDLHRPWIDKVVVRCNKCGGEAHRVPDVADVWFDSGVAFFASLGKDWEKKWKEIGPVDLVLEGHDQLRG
WFFSLLRAGVILLDRAPYNAVLVHGFMLDEQGREMHKSLGNYVEPSQVTENEKYGRDVLRLWLLRNTTWEDAKFSWKALD
QTKRDLNIIWNVYVFASTYMNLDNFDPRIYNLDNLKQYLRIEDLWLLSRYNRVVKEVKESMNDFKVHELANKMTSFIIDD
ISRFYLRLVRKRAWNESNDPDKIAMYYVLYEVLKGSLVLLSPVIPFTTERIYQDFVVDKKDSVSMESLPEVKEEFINDKI
EKEFELSKEIAEAGLNARAKAGIKLRWPIKNAYVFLVSDIDVEMANNVKEVIKFLLNTKDVEIGGIEGYRRFSKIKATPN
RGTIGPDFKRLTNKIVEYIENNSEKVASDIIAKGYHEVVIEGEPVQIKVNHVNILEETEEGYISARFNKGVVVLKKEISK
EEEEEGIVRDIIRRIQFMRKQLNVQINDYILLYIKAPEERTEMLKKWTDYIKSETRAKEVIIGEVKGDLILPWEIEDEEY
IIGVSKS
>Mature_1046_residues
PSKFDPLSTEKEILKFWEQNKIYEKLKEYNSKFEKKFLFIDGPPYPSSPIPHIGTVWNKVIKDCILRYERLAGFRTYDQP
GYDTHGLPIEVAIEKQLGIQKKSDIIEKIGVDNFVNKCKEFALNNASSLTANFKNIGIFMDWNNPYMTLHNDYISNSWML
IKKAYERGLLYKGVHVLHWCPRCETTLADYEVSEYKEIEDPSIYVKFKVKGSENRYLVIWTTTPWTLPANVFVMINKDYE
YAEVEVNNEILIMAKDRVSDVMKEAGIKNYKIVRTFKGVELVGLQYIHPLADIVTAQKGLDNYHIVVDAGEEVTLTEGTG
LVHSAPGHGDIDFEIGKKIGAPVVMLVNDRGEFLPEAGKYVGKNVRSAAEEIINDLKQRNALLHSGKVVHRYPVCWRCKT
PLILRAIEQWFIGVSKLKEELLKEIDNVKWVPDWGKTRIGNMVREIRDWVISRQRFWGTPLPIWICKNCGNIIVIGSRDE
LEKVAITKVPEDLHRPWIDKVVVRCNKCGGEAHRVPDVADVWFDSGVAFFASLGKDWEKKWKEIGPVDLVLEGHDQLRGW
FFSLLRAGVILLDRAPYNAVLVHGFMLDEQGREMHKSLGNYVEPSQVTENEKYGRDVLRLWLLRNTTWEDAKFSWKALDQ
TKRDLNIIWNVYVFASTYMNLDNFDPRIYNLDNLKQYLRIEDLWLLSRYNRVVKEVKESMNDFKVHELANKMTSFIIDDI
SRFYLRLVRKRAWNESNDPDKIAMYYVLYEVLKGSLVLLSPVIPFTTERIYQDFVVDKKDSVSMESLPEVKEEFINDKIE
KEFELSKEIAEAGLNARAKAGIKLRWPIKNAYVFLVSDIDVEMANNVKEVIKFLLNTKDVEIGGIEGYRRFSKIKATPNR
GTIGPDFKRLTNKIVEYIENNSEKVASDIIAKGYHEVVIEGEPVQIKVNHVNILEETEEGYISARFNKGVVVLKKEISKE
EEEEGIVRDIIRRIQFMRKQLNVQINDYILLYIKAPEERTEMLKKWTDYIKSETRAKEVIIGEVKGDLILPWEIEDEEYI
IGVSKS

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1059, Percent_Identity=30.8781869688385, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI94721241, Length=1059, Percent_Identity=30.8781869688385, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI46852147, Length=801, Percent_Identity=29.4631710362047, Blast_Score=334, Evalue=2e-91,
Organism=Homo sapiens, GI5454158, Length=857, Percent_Identity=21.2368728121354, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI268370293, Length=897, Percent_Identity=20.4013377926421, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI268370297, Length=897, Percent_Identity=20.4013377926421, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI268370295, Length=841, Percent_Identity=20.6896551724138, Blast_Score=154, Evalue=6e-37,
Organism=Homo sapiens, GI7661872, Length=196, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI2367096, Length=795, Percent_Identity=34.4654088050314, Blast_Score=438, Evalue=1e-123,
Organism=Escherichia coli, GI1790708, Length=936, Percent_Identity=21.6880341880342, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1786861, Length=950, Percent_Identity=20.8421052631579, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17541896, Length=1035, Percent_Identity=27.536231884058, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI71980946, Length=780, Percent_Identity=29.3589743589744, Blast_Score=315, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17510661, Length=927, Percent_Identity=22.1143473570658, Blast_Score=197, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI72001587, Length=807, Percent_Identity=22.9244114002478, Blast_Score=172, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1013, Percent_Identity=30.2073050345508, Blast_Score=471, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6325217, Length=825, Percent_Identity=27.7575757575758, Blast_Score=306, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321531, Length=896, Percent_Identity=21.7633928571429, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6323414, Length=584, Percent_Identity=23.6301369863014, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574730, Length=1030, Percent_Identity=29.6116504854369, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24668547, Length=1030, Percent_Identity=29.6116504854369, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24668543, Length=1030, Percent_Identity=29.6116504854369, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI281366294, Length=774, Percent_Identity=30.4909560723514, Blast_Score=333, Evalue=5e-91,
Organism=Drosophila melanogaster, GI17864482, Length=879, Percent_Identity=23.6632536973834, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24653289, Length=879, Percent_Identity=23.6632536973834, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21355675, Length=822, Percent_Identity=21.5328467153285, Blast_Score=177, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21355409, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_SULTO (Q975H9)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376312.2
- GeneID:   1458368
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0431
- NMPDR:   fig|273063.1.peg.480
- HOGENOM:   HBG577712
- ProtClustDB:   PRK06039
- BioCyc:   STOK273063:ST0431-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 121456; Mature: 121325

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 597-597

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKFDPLSTEKEILKFWEQNKIYEKLKEYNSKFEKKFLFIDGPPYPSSPIPHIGTVWNK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHH
VIKDCILRYERLAGFRTYDQPGYDTHGLPIEVAIEKQLGIQKKSDIIEKIGVDNFVNKCK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHCHHHHHHHHH
EFALNNASSLTANFKNIGIFMDWNNPYMTLHNDYISNSWMLIKKAYERGLLYKGVHVLHW
HHHCCCCHHHEECCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCHHCCHHHHEE
CPRCETTLADYEVSEYKEIEDPSIYVKFKVKGSENRYLVIWTTTPWTLPANVFVMINKDY
CCCCCCHHHCCCHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEEEEEECCC
EYAEVEVNNEILIMAKDRVSDVMKEAGIKNYKIVRTFKGVELVGLQYIHPLADIVTAQKG
CEEEEEECCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHC
LDNYHIVVDAGEEVTLTEGTGLVHSAPGHGDIDFEIGKKIGAPVVMLVNDRGEFLPEAGK
CCCEEEEEECCCEEEEECCCCCEECCCCCCCEEHHHHHCCCCCEEEEECCCCCCCCHHHH
YVGKNVRSAAEEIINDLKQRNALLHSGKVVHRYPVCWRCKTPLILRAIEQWFIGVSKLKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
ELLKEIDNVKWVPDWGKTRIGNMVREIRDWVISRQRFWGTPLPIWICKNCGNIIVIGSRD
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCC
ELEKVAITKVPEDLHRPWIDKVVVRCNKCGGEAHRVPDVADVWFDSGVAFFASLGKDWEK
CHHHHHHHCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCHHHHHHHHCHHHHH
KWKEIGPVDLVLEGHDQLRGWFFSLLRAGVILLDRAPYNAVLVHGFMLDEQGREMHKSLG
HHHHCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEEECHHHHHHHHHHC
NYVEPSQVTENEKYGRDVLRLWLLRNTTWEDAKFSWKALDQTKRDLNIIWNVYVFASTYM
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHEEHHHHHC
NLDNFDPRIYNLDNLKQYLRIEDLWLLSRYNRVVKEVKESMNDFKVHELANKMTSFIIDD
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISRFYLRLVRKRAWNESNDPDKIAMYYVLYEVLKGSLVLLSPVIPFTTERIYQDFVVDKK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCC
DSVSMESLPEVKEEFINDKIEKEFELSKEIAEAGLNARAKAGIKLRWPIKNAYVFLVSDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECC
DVEMANNVKEVIKFLLNTKDVEIGGIEGYRRFSKIKATPNRGTIGPDFKRLTNKIVEYIE
CHHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NNSEKVASDIIAKGYHEVVIEGEPVQIKVNHVNILEETEEGYISARFNKGVVVLKKEISK
CCHHHHHHHHHHCCCEEEEEECCCEEEEEEEEEEEECCCCCEEEEECCCCEEEEEHHHCC
EEEEEGIVRDIIRRIQFMRKQLNVQINDYILLYIKAPEERTEMLKKWTDYIKSETRAKEV
CHHHCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHE
IIGEVKGDLILPWEIEDEEYIIGVSKS
EEEECCCCEEEEEEECCCCEEEEECCC
>Mature Secondary Structure 
PSKFDPLSTEKEILKFWEQNKIYEKLKEYNSKFEKKFLFIDGPPYPSSPIPHIGTVWNK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHH
VIKDCILRYERLAGFRTYDQPGYDTHGLPIEVAIEKQLGIQKKSDIIEKIGVDNFVNKCK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHCHHHHHHHHH
EFALNNASSLTANFKNIGIFMDWNNPYMTLHNDYISNSWMLIKKAYERGLLYKGVHVLHW
HHHCCCCHHHEECCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCHHCCHHHHEE
CPRCETTLADYEVSEYKEIEDPSIYVKFKVKGSENRYLVIWTTTPWTLPANVFVMINKDY
CCCCCCHHHCCCHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEEEEEECCC
EYAEVEVNNEILIMAKDRVSDVMKEAGIKNYKIVRTFKGVELVGLQYIHPLADIVTAQKG
CEEEEEECCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHC
LDNYHIVVDAGEEVTLTEGTGLVHSAPGHGDIDFEIGKKIGAPVVMLVNDRGEFLPEAGK
CCCEEEEEECCCEEEEECCCCCEECCCCCCCEEHHHHHCCCCCEEEEECCCCCCCCHHHH
YVGKNVRSAAEEIINDLKQRNALLHSGKVVHRYPVCWRCKTPLILRAIEQWFIGVSKLKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
ELLKEIDNVKWVPDWGKTRIGNMVREIRDWVISRQRFWGTPLPIWICKNCGNIIVIGSRD
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCC
ELEKVAITKVPEDLHRPWIDKVVVRCNKCGGEAHRVPDVADVWFDSGVAFFASLGKDWEK
CHHHHHHHCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCHHHHHHHHCHHHHH
KWKEIGPVDLVLEGHDQLRGWFFSLLRAGVILLDRAPYNAVLVHGFMLDEQGREMHKSLG
HHHHCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEEECHHHHHHHHHHC
NYVEPSQVTENEKYGRDVLRLWLLRNTTWEDAKFSWKALDQTKRDLNIIWNVYVFASTYM
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHEEHHHHHC
NLDNFDPRIYNLDNLKQYLRIEDLWLLSRYNRVVKEVKESMNDFKVHELANKMTSFIIDD
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISRFYLRLVRKRAWNESNDPDKIAMYYVLYEVLKGSLVLLSPVIPFTTERIYQDFVVDKK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCC
DSVSMESLPEVKEEFINDKIEKEFELSKEIAEAGLNARAKAGIKLRWPIKNAYVFLVSDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECC
DVEMANNVKEVIKFLLNTKDVEIGGIEGYRRFSKIKATPNRGTIGPDFKRLTNKIVEYIE
CHHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NNSEKVASDIIAKGYHEVVIEGEPVQIKVNHVNILEETEEGYISARFNKGVVVLKKEISK
CCHHHHHHHHHHCCCEEEEEECCCEEEEEEEEEEEECCCCCEEEEECCCCEEEEEHHHCC
EEEEEGIVRDIIRRIQFMRKQLNVQINDYILLYIKAPEERTEMLKKWTDYIKSETRAKEV
CHHHCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHE
IIGEVKGDLILPWEIEDEEYIIGVSKS
EEEECCCCEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479