Click here to switch to the map view.

The map label for this gene is gtp1 [H]

Identifier: 161723845

GI number: 161723845

Start: 871161

End: 872258

Strand: Reverse

Name: gtp1 [H]

Synonym: RC0928

Alternate gene names: 161723845

Gene position: 872258-871161 (Counterclockwise)

Preceding gene: 15892852

Following gene: 15892850

Centisome position: 68.75

GC content: 37.43

Gene sequence:

>1098_bases
ATGACACTAAAACTCGGAATTGTTGGGTTGCCGAATGTCGGTAAGTCGACGTTATTTAATGCCTTAACGGCAAGTCAGGC
TGCAGATGCCGCTAATTATCCGTTTTGTACTATTGAGCCTAATAGCAGCAAAGTTTTAGTGCCTGATGCGCGTTTGCATA
AACTAGCAAGCTTAGCCGGAAGCGGTAAAATTATTCCGTCTTATATTGAGTTTGTCGATATTGCAGGGCTTGTTAAAGGA
GCAAGCAAAGGGGAAGGGCTAGGTAATAAGTTCTTATCTCATATCAGGGAAGTCGATGCAATACTGCATGTACTGCGTTG
TTTTGAAGATGAGGATATAACGCACGTACATAACAAAGTCGATCCGCTGCATGACCTCGAGATTATTGAAACGGAATTAA
TACTTGCCGATATAGAATCGGTTGAAAAGCGTTTAGCTACAAGTGAAAAACGCTTGAAGTCAGGCGATAAAGCCATGGCA
GAGCAGATAGAGCTGTTAAAAGAGGTTTATAAGGTATTAGGTGAGGATAAACCTGCAAGAGTGCTAAATGAAGCTTTAAG
AGTTGATAATTTAAAACAATTGCAGTTAATTACCTCTAAGCCCGTTTTATATATATGTAACGTACTTGAAAAAGATGCAG
CTATAGGTAATGAATTTACAAAATTAGTAGCGGAAAGAGCAAAGAAAGAAAATGCTAAAAGTGTCGTAATTTCTTCAAAA
ATAGAAGCTGAAATTGCTTTACTTGAAAGCATGGAAGAAAAGGAAGAGTTTTTAAAATTTATAGGTTTAGACGAAACAGG
GCTTAATAAAGTCATTAAAGAGGGGTATAATCTTTTAAACCTTAAAAGCTTTTTTACTATAGGACCAAAGGAAGCCCATA
GCTGGACTTTTAAAGACGGCACACTTGCACCGGCTGCTGCCGGTATTATTCATACCGATTTTGAAAAAGGTTTTATCAGA
GCAGAAGTTATCGGCTATAAAGATTACATAAATCTCGGTAGTGAAGCAAAAGCCAAGGAAGTAGGTAAAATGCGTTTAGA
GGGTAAAGAATATAAAATGCAGGATGGGGATATAGTACATTTTAGATTTAACGTTTAA

Upstream 100 bases:

>100_bases
GCCAAGCAAAATCGTTTTATGAGAAACTGAGGTATAAAATTGAATTTGCTATGCACGGTTGCGAAAAAGATTCTATAATG
TATTATTTACGGAAAAATTT

Downstream 100 bases:

>100_bases
ATAACGATCAGCTATGAAAACAATTTGACCAAAACGGTCTCTTGAAGTGCAAGATAGGCTTGATTATATAGTGCAGCAAA
TTTTGGCTGTTGCCAAGGAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTLKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDARLHKLASLAGSGKIIPSYIEFVDIAGLVKG
ASKGEGLGNKFLSHIREVDAILHVLRCFEDEDITHVHNKVDPLHDLEIIETELILADIESVEKRLATSEKRLKSGDKAMA
EQIELLKEVYKVLGEDKPARVLNEALRVDNLKQLQLITSKPVLYICNVLEKDAAIGNEFTKLVAERAKKENAKSVVISSK
IEAEIALLESMEEKEEFLKFIGLDETGLNKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDGTLAPAAAGIIHTDFEKGFIR
AEVIGYKDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVHFRFNV

Sequences:

>Translated_365_residues
MTLKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDARLHKLASLAGSGKIIPSYIEFVDIAGLVKG
ASKGEGLGNKFLSHIREVDAILHVLRCFEDEDITHVHNKVDPLHDLEIIETELILADIESVEKRLATSEKRLKSGDKAMA
EQIELLKEVYKVLGEDKPARVLNEALRVDNLKQLQLITSKPVLYICNVLEKDAAIGNEFTKLVAERAKKENAKSVVISSK
IEAEIALLESMEEKEEFLKFIGLDETGLNKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDGTLAPAAAGIIHTDFEKGFIR
AEVIGYKDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVHFRFNV
>Mature_364_residues
TLKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDARLHKLASLAGSGKIIPSYIEFVDIAGLVKGA
SKGEGLGNKFLSHIREVDAILHVLRCFEDEDITHVHNKVDPLHDLEIIETELILADIESVEKRLATSEKRLKSGDKAMAE
QIELLKEVYKVLGEDKPARVLNEALRVDNLKQLQLITSKPVLYICNVLEKDAAIGNEFTKLVAERAKKENAKSVVISSKI
EAEIALLESMEEKEEFLKFIGLDETGLNKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDGTLAPAAAGIIHTDFEKGFIRA
EVIGYKDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=45.4054054054054, Blast_Score=304, Evalue=7e-83,
Organism=Homo sapiens, GI58761502, Length=219, Percent_Identity=37.8995433789954, Blast_Score=142, Evalue=5e-34,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=50.5464480874317, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1789574, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=44.8369565217391, Blast_Score=296, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=39.9463806970509, Blast_Score=258, Evalue=8e-70,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=37.8306878306878, Blast_Score=232, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6321649, Length=155, Percent_Identity=37.4193548387097, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=44.4141689373297, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=44.4141689373297, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=44.4141689373297, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=40.9785932721713, Blast_Score=235, Evalue=4e-62,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40349; Mature: 40218

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDARLHKLASLAG
CEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECHHHHHHHHHHCC
SGKIIPSYIEFVDIAGLVKGASKGEGLGNKFLSHIREVDAILHVLRCFEDEDITHVHNKV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DPLHDLEIIETELILADIESVEKRLATSEKRLKSGDKAMAEQIELLKEVYKVLGEDKPAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHH
VLNEALRVDNLKQLQLITSKPVLYICNVLEKDAAIGNEFTKLVAERAKKENAKSVVISSK
HHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHH
IEAEIALLESMEEKEEFLKFIGLDETGLNKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCEECCCC
TLAPAAAGIIHTDFEKGFIRAEVIGYKDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVH
CCCHHHHHHEECCHHCCCEEEEEECHHHHHCCCCCHHHHHHHHHHCCCCCEECCCCCEEE
FRFNV
EEECC
>Mature Secondary Structure 
TLKLGIVGLPNVGKSTLFNALTASQAADAANYPFCTIEPNSSKVLVPDARLHKLASLAG
EEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECHHHHHHHHHHCC
SGKIIPSYIEFVDIAGLVKGASKGEGLGNKFLSHIREVDAILHVLRCFEDEDITHVHNKV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DPLHDLEIIETELILADIESVEKRLATSEKRLKSGDKAMAEQIELLKEVYKVLGEDKPAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHH
VLNEALRVDNLKQLQLITSKPVLYICNVLEKDAAIGNEFTKLVAERAKKENAKSVVISSK
HHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHH
IEAEIALLESMEEKEEFLKFIGLDETGLNKVIKEGYNLLNLKSFFTIGPKEAHSWTFKDG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCEECCCC
TLAPAAAGIIHTDFEKGFIRAEVIGYKDYINLGSEAKAKEVGKMRLEGKEYKMQDGDIVH
CCCHHHHHHEECCHHCCCEEEEEECHHHHHCCCCCHHHHHHHHHHCCCCCEECCCCCEEE
FRFNV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]