Click here to switch to the map view.

The map label for this gene is obgE [H]

Identifier: 161723839

GI number: 161723839

Start: 1210291

End: 1211283

Strand: Reverse

Name: obgE [H]

Synonym: RC1307

Alternate gene names: 161723839

Gene position: 1211283-1210291 (Counterclockwise)

Preceding gene: 15893231

Following gene: 15893223

Centisome position: 95.47

GC content: 36.25

Gene sequence:

>993_bases
ATGCATTTTATTGATGAAGTTAAAATATATATAAAAGGTGGAAACGGCGGCAATGGTTGTGTTAGTTTCCATCGTGAGAA
ATTTATTGACAGAGGCGGACCGGACGGTGGTGATGGTGGACGTGGCGGTAGTGTTATTTTCAGGAGTAATCACCATCTTA
ATACGCTAGTAAATTATCGATATAAACAGCATTTTACCGCAGAAAACGGCGAAAACGGTAAAGATTCAAATAGAAGCGGT
AAATCAGGAAAATCATTAGTTCTTGATGTTCCGATCGGTACTCAAATCTTTTCCGAGGACGGCAATATATTATTTTATGA
TTTCACTGTGGATGATCAAAGCTTTGAAATAATTAAAGGAGGAAGTGGTGGTCTTGGTAACAGCCATTTCAAATCGTCGG
TTAATCAAGCTCCAAGAAAGCGTACGGAAGGAGAAATTGCCGAAGAAATGTGGATTCATTTAAGTTTAAAACTTCTCTCT
GATGTTGGGCTTGTGGGGCTTCCAAATGCCGGTAAATCTACTTTTTTATCCGTTGTAACGGCAGCCAAGCCTAAAATTGC
CGATTATCCCTTTACTACTTTAGTGCCAAATCTTGGAGTGGTATATGTTGATGACGAAGAGTTTGTCATAGCCGATATTC
CTGGTTTAATTGAGGGGGCTCATCAAGGTCACGGACTTGGCGATAAATTCTTAAAGCATATAGAAAGATGTAATGTATTA
ATACATTTAATAGATGGCTCTAGTAATGATGTAGTTGCAGATTATAATACGGTACGTCTTGAGCTTGAATTATATTCCGA
TTATTTAAAAAATAAAATCGAAACCATATGTCTTAATAAATGCGATGTTCTCACAGATGAGGAAATACAGGAAAAAATAA
ATAAGCTGCAGAAAGCTACTAATAAAGAAATTTTTCCTATCTCTACCTGCACTAATGCTGGAGTAAATAAAATAGTTAAA
CTTGCTTTAGAGACTATAAAAAATCAGAAGTAA

Upstream 100 bases:

>100_bases
GTCATTGCGAGCGACTGCAAGGAGCGTAGCAATCTCAAGAGATTTGATGAGATTTCCACGTCGCTTCGCGCCTTGTAATG
ACGTTGAAAATATAAATCAT

Downstream 100 bases:

>100_bases
TACTACTAGGTATTGCCTGCGTGGATACTGAGGATTGTCATTACGAGGATTCCTGAGATTGCCACGTTCACTAACGTTCG
CTGGCAATGACAATGAATAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MHFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKDSNRSG
KSGKSLVLDVPIGTQIFSEDGNILFYDFTVDDQSFEIIKGGSGGLGNSHFKSSVNQAPRKRTEGEIAEEMWIHLSLKLLS
DVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPNLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
IHLIDGSSNDVVADYNTVRLELELYSDYLKNKIETICLNKCDVLTDEEIQEKINKLQKATNKEIFPISTCTNAGVNKIVK
LALETIKNQK

Sequences:

>Translated_330_residues
MHFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKDSNRSG
KSGKSLVLDVPIGTQIFSEDGNILFYDFTVDDQSFEIIKGGSGGLGNSHFKSSVNQAPRKRTEGEIAEEMWIHLSLKLLS
DVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPNLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
IHLIDGSSNDVVADYNTVRLELELYSDYLKNKIETICLNKCDVLTDEEIQEKINKLQKATNKEIFPISTCTNAGVNKIVK
LALETIKNQK
>Mature_330_residues
MHFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKDSNRSG
KSGKSLVLDVPIGTQIFSEDGNILFYDFTVDDQSFEIIKGGSGGLGNSHFKSSVNQAPRKRTEGEIAEEMWIHLSLKLLS
DVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPNLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
IHLIDGSSNDVVADYNTVRLELELYSDYLKNKIETICLNKCDVLTDEEIQEKINKLQKATNKEIFPISTCTNAGVNKIVK
LALETIKNQK

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=37.6947040498442, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI111955139, Length=359, Percent_Identity=33.7047353760446, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI111955063, Length=258, Percent_Identity=34.8837209302326, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI58761500, Length=106, Percent_Identity=39.622641509434, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4557537, Length=92, Percent_Identity=38.0434782608696, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789574, Length=324, Percent_Identity=49.0740740740741, Blast_Score=273, Evalue=8e-75,
Organism=Escherichia coli, GI1787454, Length=107, Percent_Identity=38.3177570093458, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=40.1215805471125, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17552324, Length=323, Percent_Identity=30.6501547987616, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=129, Percent_Identity=36.4341085271318, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71981008, Length=91, Percent_Identity=35.1648351648352, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=191, Percent_Identity=36.1256544502618, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=87, Percent_Identity=39.0804597701149, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=310, Percent_Identity=40.3225806451613, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24585318, Length=304, Percent_Identity=33.8815789473684, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24640873, Length=144, Percent_Identity=36.1111111111111, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640877, Length=144, Percent_Identity=36.1111111111111, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640875, Length=144, Percent_Identity=36.1111111111111, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356473, Length=92, Percent_Identity=34.7826086956522, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36226; Mature: 36226

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYR
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
YKQHFTAENGENGKDSNRSGKSGKSLVLDVPIGTQIFSEDGNILFYDFTVDDQSFEIIKG
HHHEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEEEEECCCCEEEEEC
GSGGLGNSHFKSSVNQAPRKRTEGEIAEEMWIHLSLKLLSDVGLVGLPNAGKSTFLSVVT
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCEE
IHLIDGSSNDVVADYNTVRLELELYSDYLKNKIETICLNKCDVLTDEEIQEKINKLQKAT
EEEEECCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
NKEIFPISTCTNAGVNKIVKLALETIKNQK
CCCEEEECCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYR
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
YKQHFTAENGENGKDSNRSGKSGKSLVLDVPIGTQIFSEDGNILFYDFTVDDQSFEIIKG
HHHEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEEEEECCCCEEEEEC
GSGGLGNSHFKSSVNQAPRKRTEGEIAEEMWIHLSLKLLSDVGLVGLPNAGKSTFLSVVT
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCEE
IHLIDGSSNDVVADYNTVRLELELYSDYLKNKIETICLNKCDVLTDEEIQEKINKLQKAT
EEEEECCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
NKEIFPISTCTNAGVNKIVKLALETIKNQK
CCCEEEECCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA