| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
Click here to switch to the map view.
The map label for this gene is dnaX [H]
Identifier: 161621801
GI number: 161621801
Start: 253133
End: 255835
Strand: Direct
Name: dnaX [H]
Synonym: PPA0204
Alternate gene names: 161621801
Gene position: 253133-255835 (Clockwise)
Preceding gene: 50841695
Following gene: 50841697
Centisome position: 9.89
GC content: 63.34
Gene sequence:
>2703_bases TTGCTGGACGGCCCCGAGACCCCTGAGGAACCCGACGGCCTCGAGACAGACGAGGACGAGGAGGATGGGGCTGACGTTAT TGAGCGGGTTCAGGAATTAATCGGGGAAGCCCCTGACAGTAACCCCGATGACGATCTTCCAGAGCTTCCGCTGGCCCTCT ACCGGCGTTACCGTCCGGAGACCTTCGATGAGGTTATTGGTGAGGATCATGTTATTGAGCCTCTCAAGCGCGCGATCCTT AATAACCGCGTCAACCATGCCTACTTGTTTTCAGGGCCACGTGGCTGTGGCAAGACGACGACCGCCCGCATTCTTGCCCG AGCGCTGAACTGTGAGCAGGGTCCGACGCCGACTCCCTGCGGAACGTGTCAGTCCTGTCGCGACCTGGCCTGTGGTGGAC CCGGATCGATTGACGTCATCGAGATTGACGCTGCCTCCCACGGCGGGGTCGATGACGCACGTGATTTACGCGAACGCGCC TTTTTCGCCCCAGTACATTCGCGTTACAAGATCTACATCATCGATGAGGCCCACATGGTCACCCCGCAGGGCTTTAACGC CTTGCTGAAACTCGTCGAGGAGCCCCCGCCACACGTCAAGTTCATCTTCGCCACCACAGAACCGGAAAAGGTCATCGGGA CGATTCGCTCCCGGACTCACCACTACCCGTTCCGCCTTGTGCCGCCGAAGGTGCTCGTCGAGTATCTGGCTGAGCTATGC GGCAAGGAGGGGATCGACGTCGACCACGCCGTCCTGCCGCTGGTGGTGCGTGCCGGTGGTGGGTCGGTGCGAGACAGCCT TTCGGTGCTTGACCAGCTTCTCGGCGGTGCTGCTGATGGCCATGTCAGCTACGAGCAGGCTGCGGCCCTCCTCGGCTACA CCCCAGAGGCCCTTCTAGACGAGATCGTTGACGCCTTTGCCGCCGGGGACGCCCACCAGGTTTTTGCCACGATCGACAAG GTCATCGAGGTAGGTCAGGACCCTCGCCGTTTCGCTGAGGACCTGCTGCGTCGCATGCGCGACCTCGTCATCGTCTCGGC GGTCCCTGACGCCTGCCGGAGCGGACTCATCGATGTCTCACCGGAGCAGGCCACCAGACTTGCTCACCAGGTTTCTGGTT TCGGCGCAGGCGAACTCACCCGCGCTGCCGAGGTATTGGCCACCGGGCTAACTAACATGCGCGGCACTACCGCTCCCCGG CTCCACCTGGAGCTGATGTGCTCGCGGATTCTCCTACCCGGAGCCGACACGGATGGTCGTGGAATCCATGCACGTTTGGA GCGGTTAGAGAGGAGGATCGGCGTCTCCGGCCCCGTTGAGGAGGTCGAACGTGCTGAGCGTCCGGTCACCGCCCAGCCTC CCACTCGCTATGCGGACACACCACAGCAGGCTAGTCCTCCTCAGCACTGGCCAGCGGAGAACCTTCAAAACCCGGAGCGT CGGTCCGCACCAGAACACCACGACGCCCCGTCGCCCGGACAGCGTCCATCTGGGCGTCCACGTCCCAGCCGTAAGGATTA CCGGCCCGGCAATCAGCTTGCTGAACAGCCGCCGTCCAACCAGCACGGCGATGATGGTCAGATGTCGCAGGGACCAAGGC AGCAGGGCGGTCCGTCAACCAGTCAGCGCCAGCAACCCAGACCTCAGGACCACCAGCCGTCTCAGCGGGATCGTCAGGAC ACCCCACCGGCCCAACCTCAACAGCCTTCCGCCGAACAAGGCGGTCGCGCCGACGATGCCATAAACATCACCACCTTGCG TCGCGAGTGGCCGCAGGTCCTCGAAGCCGTCAAGGATGGCGGACGTGTCGCATGGATGGTCCTCAATCAGTACGCCCAGG TGCTTGAGGTTCACGGCAATCAGGCCACCTTGGGATTCTCTAATATCGGAGCCCGGGAAAATTTCGCTGCCGGTAATTAC CCGAAGGTCTTGCATGACGCCGTTGTGAAGGTGCTGGGAGTGGACCTGGCCTTCACTGCGGTCGTCGGGGAGCCTCCGGC CGCCGTCCGCCCCGAGTCCCATCCTGCTGAGTTTCAGAGTGGACCGGCTGCCCAGGAACCACCGGATGACGATCCCTGGG AGCAAGGGCCACACCATCAAGACTCGACGCGAGGTGGCGAACCGTCGGACCCTACTCATCCCGGTCGGGATCCTCAGGGC CGACCGGGTGACCGTCAGGCGATTTCCGACGACGCTTCAAAGGATGCGCCACCCCCGCCGGTGACCAGCTCCCATCCCAG CGAGGCTGGGGACGACGATCCTGCCCCTGATGCCACGACCGAGGACCAGTCCGCAGATGTCCGCGATGAGGTCGTGGAAT CGGGACCCGTAGCTGGCGCCCCAGACCCTGACAGCGGTGGAGCTGCCGAACCTAAACCTGATCTGGTGCCAGGCCAGGAT CACGTCGAGGCTGCCGGACGCGCTGAGTCTGCGCGGCAGATCGACCCTGGTGGCGCATCCTCGCAAGGCCGTCCCTCCGC TGCTGCGGTCAGTACCGCGCACCGTTGGAGTGAGCGCGCTAAAGGAAGTGTTCGCCCTCTTGAGGTGACTTCGCGGTCAG CCCAGGTCGAGGAGCCGCCTGATGACGGCGGGGAGTGGGACGACACCGTTGTGGAGGAGTCCAACGAGAGTCCGATTGAC CTCATCATGCGCGAGCTAGGTGGGGTCGTCATAGACACCGACGGTGACTCAACCGCCAGATGA
Upstream 100 bases:
>100_bases TCCGGATCTTTTCGGTGACGAGGAGTCGCCGCGCCCCGTCATGCCTCCTGACGAAGCTACCCCTGATGATGACCTTCCCT CGGATCCGTGCGATCCAGGG
Downstream 100 bases:
>100_bases ATGCGAGCGGGAATATATCAACCCAGAATCTCGTCGTTACCGACGGCTACTGTGGATGACGACACCGCCCCACCGGCGAG GACCAGGGGCCACACACACG
Product: DNA polymerase III subunits gamma and tau
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 900; Mature: 900
Protein sequence:
>900_residues MLDGPETPEEPDGLETDEDEEDGADVIERVQELIGEAPDSNPDDDLPELPLALYRRYRPETFDEVIGEDHVIEPLKRAIL NNRVNHAYLFSGPRGCGKTTTARILARALNCEQGPTPTPCGTCQSCRDLACGGPGSIDVIEIDAASHGGVDDARDLRERA FFAPVHSRYKIYIIDEAHMVTPQGFNALLKLVEEPPPHVKFIFATTEPEKVIGTIRSRTHHYPFRLVPPKVLVEYLAELC GKEGIDVDHAVLPLVVRAGGGSVRDSLSVLDQLLGGAADGHVSYEQAAALLGYTPEALLDEIVDAFAAGDAHQVFATIDK VIEVGQDPRRFAEDLLRRMRDLVIVSAVPDACRSGLIDVSPEQATRLAHQVSGFGAGELTRAAEVLATGLTNMRGTTAPR LHLELMCSRILLPGADTDGRGIHARLERLERRIGVSGPVEEVERAERPVTAQPPTRYADTPQQASPPQHWPAENLQNPER RSAPEHHDAPSPGQRPSGRPRPSRKDYRPGNQLAEQPPSNQHGDDGQMSQGPRQQGGPSTSQRQQPRPQDHQPSQRDRQD TPPAQPQQPSAEQGGRADDAINITTLRREWPQVLEAVKDGGRVAWMVLNQYAQVLEVHGNQATLGFSNIGARENFAAGNY PKVLHDAVVKVLGVDLAFTAVVGEPPAAVRPESHPAEFQSGPAAQEPPDDDPWEQGPHHQDSTRGGEPSDPTHPGRDPQG RPGDRQAISDDASKDAPPPPVTSSHPSEAGDDDPAPDATTEDQSADVRDEVVESGPVAGAPDPDSGGAAEPKPDLVPGQD HVEAAGRAESARQIDPGGASSQGRPSAAAVSTAHRWSERAKGSVRPLEVTSRSAQVEEPPDDGGEWDDTVVEESNESPID LIMRELGGVVIDTDGDSTAR
Sequences:
>Translated_900_residues MLDGPETPEEPDGLETDEDEEDGADVIERVQELIGEAPDSNPDDDLPELPLALYRRYRPETFDEVIGEDHVIEPLKRAIL NNRVNHAYLFSGPRGCGKTTTARILARALNCEQGPTPTPCGTCQSCRDLACGGPGSIDVIEIDAASHGGVDDARDLRERA FFAPVHSRYKIYIIDEAHMVTPQGFNALLKLVEEPPPHVKFIFATTEPEKVIGTIRSRTHHYPFRLVPPKVLVEYLAELC GKEGIDVDHAVLPLVVRAGGGSVRDSLSVLDQLLGGAADGHVSYEQAAALLGYTPEALLDEIVDAFAAGDAHQVFATIDK VIEVGQDPRRFAEDLLRRMRDLVIVSAVPDACRSGLIDVSPEQATRLAHQVSGFGAGELTRAAEVLATGLTNMRGTTAPR LHLELMCSRILLPGADTDGRGIHARLERLERRIGVSGPVEEVERAERPVTAQPPTRYADTPQQASPPQHWPAENLQNPER RSAPEHHDAPSPGQRPSGRPRPSRKDYRPGNQLAEQPPSNQHGDDGQMSQGPRQQGGPSTSQRQQPRPQDHQPSQRDRQD TPPAQPQQPSAEQGGRADDAINITTLRREWPQVLEAVKDGGRVAWMVLNQYAQVLEVHGNQATLGFSNIGARENFAAGNY PKVLHDAVVKVLGVDLAFTAVVGEPPAAVRPESHPAEFQSGPAAQEPPDDDPWEQGPHHQDSTRGGEPSDPTHPGRDPQG RPGDRQAISDDASKDAPPPPVTSSHPSEAGDDDPAPDATTEDQSADVRDEVVESGPVAGAPDPDSGGAAEPKPDLVPGQD HVEAAGRAESARQIDPGGASSQGRPSAAAVSTAHRWSERAKGSVRPLEVTSRSAQVEEPPDDGGEWDDTVVEESNESPID LIMRELGGVVIDTDGDSTAR >Mature_900_residues MLDGPETPEEPDGLETDEDEEDGADVIERVQELIGEAPDSNPDDDLPELPLALYRRYRPETFDEVIGEDHVIEPLKRAIL NNRVNHAYLFSGPRGCGKTTTARILARALNCEQGPTPTPCGTCQSCRDLACGGPGSIDVIEIDAASHGGVDDARDLRERA FFAPVHSRYKIYIIDEAHMVTPQGFNALLKLVEEPPPHVKFIFATTEPEKVIGTIRSRTHHYPFRLVPPKVLVEYLAELC GKEGIDVDHAVLPLVVRAGGGSVRDSLSVLDQLLGGAADGHVSYEQAAALLGYTPEALLDEIVDAFAAGDAHQVFATIDK VIEVGQDPRRFAEDLLRRMRDLVIVSAVPDACRSGLIDVSPEQATRLAHQVSGFGAGELTRAAEVLATGLTNMRGTTAPR LHLELMCSRILLPGADTDGRGIHARLERLERRIGVSGPVEEVERAERPVTAQPPTRYADTPQQASPPQHWPAENLQNPER RSAPEHHDAPSPGQRPSGRPRPSRKDYRPGNQLAEQPPSNQHGDDGQMSQGPRQQGGPSTSQRQQPRPQDHQPSQRDRQD TPPAQPQQPSAEQGGRADDAINITTLRREWPQVLEAVKDGGRVAWMVLNQYAQVLEVHGNQATLGFSNIGARENFAAGNY PKVLHDAVVKVLGVDLAFTAVVGEPPAAVRPESHPAEFQSGPAAQEPPDDDPWEQGPHHQDSTRGGEPSDPTHPGRDPQG RPGDRQAISDDASKDAPPPPVTSSHPSEAGDDDPAPDATTEDQSADVRDEVVESGPVAGAPDPDSGGAAEPKPDLVPGQD HVEAAGRAESARQIDPGGASSQGRPSAAAVSTAHRWSERAKGSVRPLEVTSRSAQVEEPPDDGGEWDDTVVEESNESPID LIMRELGGVVIDTDGDSTAR
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]
COG id: COG2812
COG function: function code L; DNA polymerase III, gamma/tau subunits
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Homo sapiens, GI6677723, Length=268, Percent_Identity=24.2537313432836, Blast_Score=73, Evalue=2e-12, Organism=Homo sapiens, GI4506491, Length=317, Percent_Identity=22.7129337539432, Blast_Score=72, Evalue=3e-12, Organism=Homo sapiens, GI31881687, Length=317, Percent_Identity=22.7129337539432, Blast_Score=72, Evalue=3e-12, Organism=Homo sapiens, GI194306571, Length=268, Percent_Identity=24.2537313432836, Blast_Score=70, Evalue=8e-12, Organism=Homo sapiens, GI194306567, Length=268, Percent_Identity=24.2537313432836, Blast_Score=70, Evalue=8e-12, Organism=Escherichia coli, GI1786676, Length=300, Percent_Identity=40, Blast_Score=234, Evalue=1e-62, Organism=Caenorhabditis elegans, GI71986063, Length=323, Percent_Identity=25.077399380805, Blast_Score=69, Evalue=9e-12, Organism=Drosophila melanogaster, GI17647857, Length=315, Percent_Identity=25.0793650793651, Blast_Score=80, Evalue=5e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008921 - InterPro: IPR022754 - InterPro: IPR012763 [H]
Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 96844; Mature: 96844
Theoretical pI: Translated: 4.50; Mature: 4.50
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLDGPETPEEPDGLETDEDEEDGADVIERVQELIGEAPDSNPDDDLPELPLALYRRYRPE CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCC TFDEVIGEDHVIEPLKRAILNNRVNHAYLFSGPRGCGKTTTARILARALNCEQGPTPTPC HHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC GTCQSCRDLACGGPGSIDVIEIDAASHGGVDDARDLRERAFFAPVHSRYKIYIIDEAHMV CCHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC TPQGFNALLKLVEEPPPHVKFIFATTEPEKVIGTIRSRTHHYPFRLVPPKVLVEYLAELC CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH GKEGIDVDHAVLPLVVRAGGGSVRDSLSVLDQLLGGAADGHVSYEQAAALLGYTPEALLD CCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHH EIVDAFAAGDAHQVFATIDKVIEVGQDPRRFAEDLLRRMRDLVIVSAVPDACRSGLIDVS HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEHHCCCHHHHCCCCCCC PEQATRLAHQVSGFGAGELTRAAEVLATGLTNMRGTTAPRLHLELMCSRILLPGADTDGR HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC GIHARLERLERRIGVSGPVEEVERAERPVTAQPPTRYADTPQQASPPQHWPAENLQNPER HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHH RSAPEHHDAPSPGQRPSGRPRPSRKDYRPGNQLAEQPPSNQHGDDGQMSQGPRQQGGPST HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC SQRQQPRPQDHQPSQRDRQDTPPAQPQQPSAEQGGRADDAINITTLRREWPQVLEAVKDG CHHCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHCC GRVAWMVLNQYAQVLEVHGNQATLGFSNIGARENFAAGNYPKVLHDAVVKVLGVDLAFTA CCEEHHHHHHHHHHHHHCCCCEEECHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEE VVGEPPAAVRPESHPAEFQSGPAAQEPPDDDPWEQGPHHQDSTRGGEPSDPTHPGRDPQG HCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC RPGDRQAISDDASKDAPPPPVTSSHPSEAGDDDPAPDATTEDQSADVRDEVVESGPVAGA CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC PDPDSGGAAEPKPDLVPGQDHVEAAGRAESARQIDPGGASSQGRPSAAAVSTAHRWSERA CCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH KGSVRPLEVTSRSAQVEEPPDDGGEWDDTVVEESNESPIDLIMRELGGVVIDTDGDSTAR CCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCEEEECCCCCCCC >Mature Secondary Structure MLDGPETPEEPDGLETDEDEEDGADVIERVQELIGEAPDSNPDDDLPELPLALYRRYRPE CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCC TFDEVIGEDHVIEPLKRAILNNRVNHAYLFSGPRGCGKTTTARILARALNCEQGPTPTPC HHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC GTCQSCRDLACGGPGSIDVIEIDAASHGGVDDARDLRERAFFAPVHSRYKIYIIDEAHMV CCHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC TPQGFNALLKLVEEPPPHVKFIFATTEPEKVIGTIRSRTHHYPFRLVPPKVLVEYLAELC CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH GKEGIDVDHAVLPLVVRAGGGSVRDSLSVLDQLLGGAADGHVSYEQAAALLGYTPEALLD CCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHH EIVDAFAAGDAHQVFATIDKVIEVGQDPRRFAEDLLRRMRDLVIVSAVPDACRSGLIDVS HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEHHCCCHHHHCCCCCCC PEQATRLAHQVSGFGAGELTRAAEVLATGLTNMRGTTAPRLHLELMCSRILLPGADTDGR HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC GIHARLERLERRIGVSGPVEEVERAERPVTAQPPTRYADTPQQASPPQHWPAENLQNPER HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHH RSAPEHHDAPSPGQRPSGRPRPSRKDYRPGNQLAEQPPSNQHGDDGQMSQGPRQQGGPST HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC SQRQQPRPQDHQPSQRDRQDTPPAQPQQPSAEQGGRADDAINITTLRREWPQVLEAVKDG CHHCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHCC GRVAWMVLNQYAQVLEVHGNQATLGFSNIGARENFAAGNYPKVLHDAVVKVLGVDLAFTA CCEEHHHHHHHHHHHHHCCCCEEECHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEE VVGEPPAAVRPESHPAEFQSGPAAQEPPDDDPWEQGPHHQDSTRGGEPSDPTHPGRDPQG HCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC RPGDRQAISDDASKDAPPPPVTSSHPSEAGDDDPAPDATTEDQSADVRDEVVESGPVAGA CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC PDPDSGGAAEPKPDLVPGQDHVEAAGRAESARQIDPGGASSQGRPSAAAVSTAHRWSERA CCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH KGSVRPLEVTSRSAQVEEPPDDGGEWDDTVVEESNESPIDLIMRELGGVVIDTDGDSTAR CCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]