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The map label for this gene is serC [H]

Identifier: 161621314

GI number: 161621314

Start: 3807662

End: 3808744

Strand: Reverse

Name: serC [H]

Synonym: Bxe_A0976

Alternate gene names: 161621314

Gene position: 3808744-3807662 (Counterclockwise)

Preceding gene: 91784818

Following gene: 91784816

Centisome position: 77.8

GC content: 61.5

Gene sequence:

>1083_bases
ATGCGCGTCTTTAATTTCTCCGCCGGCCCAGCGGCCATGCCCGAAGAAGTTCTGCGTCAAGCTGCCGACGAAATGCTCGA
TTGGCAAGGCAGCGGCATGAGCGTGATGGAAATGAGCCATCGCGGGAAAGAGTTCATGTCGATCCATGAGGAAGCGCTCG
TCGATCTGCGCGACCTGCTTCAGGTGCCGGCGAGTCACCGCATCCTGTTCCTGCAAGGTGGCGGTTTGGGCGAGAACGCA
ATCGTGCCGATGAACCTGATGGGCGCCAAGCCGCGCGCGGATTTCGTCGTGACGGGTTCGTGGTCGCAGAAGTCGTTCAG
GGAAGCGCAGAAGTACGGCACCGTGCATCTGGCGGCGAGCGGTCAGACAGCCGATGGTTTCACCCGCGCGCCCGCCCGCT
CGGAATGGCAACTGTCGGACGACCCGGCTTACGTGCATCTGTGCACGAACGAGACGATCCACGGCGTCGAGACATTCGAG
ATCCCCGATCTCGGCGATATTCCGCTCGTGGCGGATGCCTCGTCGCACATCCTGTCGCGTCCTATGGACATCGCCAAATA
CGGCGTGCTGTTCGGCGGCGCGCAGAAGAACATCGGCATGGCGGGCGTGACGGTGGTGGTCGTGCGCGAAGACATGCTCG
ATCGCGCGCAGCCGATCTGCCCGTCGGCGTTCGAATGGAAGATCGTCGCCGAGAACAATTCGATGTACAACACGCCGCCC
ACTTACGCGATCTACATCGCCGGGCTGGTGTTCAAGTGGTTGAAGAAGCAGGGCGGCCTTGCCGCGATGGAAGCGCGTAA
CCTCGAAAAGTCGAAGCTGCTGTACGACGCGATCGACGCGAGCAGCTTCTATCTGAACAAGGTCGAACGCGGTTCGCGCT
CGCGGATGAACGTGCCGTTCTTCCTCGCCGACGAGTCCCGCAACGAAGATTTCCTGGCCGGCGCGAAAGCGCGGGGAATG
GTGCAGCTAAAGGGCCACAAGTCCGTCGGCGGCATGCGGGCGTCGATTTATAACGCCGTCCCGCTCGAGGGCGTCAAAGC
GCTTGTCGAATACATGAAGGAATTCGAACAGCGCAGCGCCTGA

Upstream 100 bases:

>100_bases
CAATCGCGTTGTCATCTTCACGGTCAATGCCGGCCCGGCTGTCAGCTTCGCCGATTTTTGCGCGATCTTCATTTTTCGCG
CCCGCTTCCAGGATCTCACG

Downstream 100 bases:

>100_bases
GTCATCACGGCGCGTGCATCCTTTCCAGCACGCATTTGTGCAGCAGCCACCGGCAAGGCCGTTTTCACGCATGGACGACG
AACTCAATACCCGACTCAAA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRVFNFSAGPAAMPEEVLRQAADEMLDWQGSGMSVMEMSHRGKEFMSIHEEALVDLRDLLQVPASHRILFLQGGGLGENA
IVPMNLMGAKPRADFVVTGSWSQKSFREAQKYGTVHLAASGQTADGFTRAPARSEWQLSDDPAYVHLCTNETIHGVETFE
IPDLGDIPLVADASSHILSRPMDIAKYGVLFGGAQKNIGMAGVTVVVVREDMLDRAQPICPSAFEWKIVAENNSMYNTPP
TYAIYIAGLVFKWLKKQGGLAAMEARNLEKSKLLYDAIDASSFYLNKVERGSRSRMNVPFFLADESRNEDFLAGAKARGM
VQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKEFEQRSA

Sequences:

>Translated_360_residues
MRVFNFSAGPAAMPEEVLRQAADEMLDWQGSGMSVMEMSHRGKEFMSIHEEALVDLRDLLQVPASHRILFLQGGGLGENA
IVPMNLMGAKPRADFVVTGSWSQKSFREAQKYGTVHLAASGQTADGFTRAPARSEWQLSDDPAYVHLCTNETIHGVETFE
IPDLGDIPLVADASSHILSRPMDIAKYGVLFGGAQKNIGMAGVTVVVVREDMLDRAQPICPSAFEWKIVAENNSMYNTPP
TYAIYIAGLVFKWLKKQGGLAAMEARNLEKSKLLYDAIDASSFYLNKVERGSRSRMNVPFFLADESRNEDFLAGAKARGM
VQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKEFEQRSA
>Mature_360_residues
MRVFNFSAGPAAMPEEVLRQAADEMLDWQGSGMSVMEMSHRGKEFMSIHEEALVDLRDLLQVPASHRILFLQGGGLGENA
IVPMNLMGAKPRADFVVTGSWSQKSFREAQKYGTVHLAASGQTADGFTRAPARSEWQLSDDPAYVHLCTNETIHGVETFE
IPDLGDIPLVADASSHILSRPMDIAKYGVLFGGAQKNIGMAGVTVVVVREDMLDRAQPICPSAFEWKIVAENNSMYNTPP
TYAIYIAGLVFKWLKKQGGLAAMEARNLEKSKLLYDAIDASSFYLNKVERGSRSRMNVPFFLADESRNEDFLAGAKARGM
VQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKEFEQRSA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.6454293628809, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=43.4173669467787, Blast_Score=301, Evalue=8e-82,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=54.4692737430168, Blast_Score=413, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=46.1325966850829, Blast_Score=340, Evalue=9e-94,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=40.9326424870466, Blast_Score=288, Evalue=8e-79,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=47.9338842975207, Blast_Score=359, Evalue=1e-99,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39633; Mature: 39633

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFNFSAGPAAMPEEVLRQAADEMLDWQGSGMSVMEMSHRGKEFMSIHEEALVDLRDLL
CEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
QVPASHRILFLQGGGLGENAIVPMNLMGAKPRADFVVTGSWSQKSFREAQKYGTVHLAAS
HCCCCCEEEEEECCCCCCCCEEEEHCCCCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEC
GQTADGFTRAPARSEWQLSDDPAYVHLCTNETIHGVETFEIPDLGDIPLVADASSHILSR
CCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCCCEEECCHHHHHHC
PMDIAKYGVLFGGAQKNIGMAGVTVVVVREDMLDRAQPICPSAFEWKIVAENNSMYNTPP
CHHHHHHHHEECCCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCEEEEEEECCCCCCCCCC
TYAIYIAGLVFKWLKKQGGLAAMEARNLEKSKLLYDAIDASSFYLNKVERGSRSRMNVPF
CHHHHHHHHHHHHHHHCCCEEEHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCE
FLADESRNEDFLAGAKARGMVQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKEFEQRSA
EEECCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVFNFSAGPAAMPEEVLRQAADEMLDWQGSGMSVMEMSHRGKEFMSIHEEALVDLRDLL
CEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
QVPASHRILFLQGGGLGENAIVPMNLMGAKPRADFVVTGSWSQKSFREAQKYGTVHLAAS
HCCCCCEEEEEECCCCCCCCEEEEHCCCCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEC
GQTADGFTRAPARSEWQLSDDPAYVHLCTNETIHGVETFEIPDLGDIPLVADASSHILSR
CCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCCCEEECCHHHHHHC
PMDIAKYGVLFGGAQKNIGMAGVTVVVVREDMLDRAQPICPSAFEWKIVAENNSMYNTPP
CHHHHHHHHEECCCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCEEEEEEECCCCCCCCCC
TYAIYIAGLVFKWLKKQGGLAAMEARNLEKSKLLYDAIDASSFYLNKVERGSRSRMNVPF
CHHHHHHHHHHHHHHHCCCEEEHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCE
FLADESRNEDFLAGAKARGMVQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKEFEQRSA
EEECCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA