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The map label for this gene is tsf

Identifier: 161611310

GI number: 161611310

Start: 209889

End: 210737

Strand: Direct

Name: tsf

Synonym: pc0137

Alternate gene names: 161611310

Gene position: 209889-210737 (Clockwise)

Preceding gene: 46445770

Following gene: 46445772

Centisome position: 8.69

GC content: 36.63

Gene sequence:

>849_bases
ATGGCGGCTGTAACTCCTGCGTTGATTAAAGAACTGCGCGAACGCACTGGCGTTGGCATGGGAAAATGTAAAGAAGCATT
AGAAGAAGCAAATGGTGATATGGAGTTGGCAATTGCCAATCTTCGTAAAGCTGGAATGGCTTCTGCAGTAAAAAAAGAAG
GCCGCGAAACGAAAGAAGGTATGATCGGTACAGCTGAAAATGAAAAAACAATAGCAATTGTTGAAGTCAATGCTGAAACT
GATTTCGTTGTGAAGAACGAAAGATTTAAAGAATTTCTTGAAAACATTGCTCGTGAAGTAGCAAATACTAATCCTTCTTC
TCTAGACGCATTTTTACAGCAAAAGTATTCAAAAGAATCTTCTTTGACTGTTGACCAATACAGAGCAACAATCGTTCAAA
CGATTGGTGAAAATATTCAGATCAAACGTATTATGACTCTACAGAAAAGCCCAGAGCGTTCATTTGGTATTTATTCGCAT
TTAGGCGGAAAAATTGTAACGATGGTGGAAATTACTGGTAGTAATCAAGAAGAAGCCTTAGCTAAAGATATTGCGATGCA
TATTGCGGCTACTGCACCTGACTACTTATCTCCAGAAAAAATTCCGCAAGAAATTATTACAAGTGAAAAAGACATTGCAA
AAGGTCAAATTCAAGGAAAGCCTGCTAATATTGTCGATAAAATCGTAGAAGGAAAAATTAATGCATTCTATGATACTAAT
TGTTTAGTGCGCCAAAAATACATCAAAGATGATAGTTTAAGCATTACAGATTTAGTAAATCAACGTAGCAAAGTAGTTGG
CAAAGAATTAGCTGTTACAAACTTCATTCGTTGGAATGTGGGCCAATAA

Upstream 100 bases:

>100_bases
GAAGAACAAACTGAAGAAGCCGAAGAAGAAACTTTATCTTCTAAGTATCGTGAACAAGATTTTCAAGAAGCTAAGAGTGG
TGCAAGAGGAGAAAAATAAT

Downstream 100 bases:

>100_bases
TAATCATTTATCTTAATGATTTCATTCAAAGGGTTTAGATAAAAATTTATCTAAACCCTTTTTTATTTAAAGTGCCTCTA
ATTCATCAAAATTTACTAAG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MAAVTPALIKELRERTGVGMGKCKEALEEANGDMELAIANLRKAGMASAVKKEGRETKEGMIGTAENEKTIAIVEVNAET
DFVVKNERFKEFLENIAREVANTNPSSLDAFLQQKYSKESSLTVDQYRATIVQTIGENIQIKRIMTLQKSPERSFGIYSH
LGGKIVTMVEITGSNQEEALAKDIAMHIAATAPDYLSPEKIPQEIITSEKDIAKGQIQGKPANIVDKIVEGKINAFYDTN
CLVRQKYIKDDSLSITDLVNQRSKVVGKELAVTNFIRWNVGQ

Sequences:

>Translated_282_residues
MAAVTPALIKELRERTGVGMGKCKEALEEANGDMELAIANLRKAGMASAVKKEGRETKEGMIGTAENEKTIAIVEVNAET
DFVVKNERFKEFLENIAREVANTNPSSLDAFLQQKYSKESSLTVDQYRATIVQTIGENIQIKRIMTLQKSPERSFGIYSH
LGGKIVTMVEITGSNQEEALAKDIAMHIAATAPDYLSPEKIPQEIITSEKDIAKGQIQGKPANIVDKIVEGKINAFYDTN
CLVRQKYIKDDSLSITDLVNQRSKVVGKELAVTNFIRWNVGQ
>Mature_281_residues
AAVTPALIKELRERTGVGMGKCKEALEEANGDMELAIANLRKAGMASAVKKEGRETKEGMIGTAENEKTIAIVEVNAETD
FVVKNERFKEFLENIAREVANTNPSSLDAFLQQKYSKESSLTVDQYRATIVQTIGENIQIKRIMTLQKSPERSFGIYSHL
GGKIVTMVEITGSNQEEALAKDIAMHIAATAPDYLSPEKIPQEIITSEKDIAKGQIQGKPANIVDKIVEGKINAFYDTNC
LVRQKYIKDDSLSITDLVNQRSKVVGKELAVTNFIRWNVGQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=225, Percent_Identity=29.7777777777778, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=40, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=40, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI291084500, Length=100, Percent_Identity=40, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786366, Length=288, Percent_Identity=37.5, Blast_Score=169, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17561440, Length=213, Percent_Identity=29.1079812206573, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19921466, Length=253, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PARUW (Q6MEY8)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007136.2
- ProteinModelPortal:   Q6MEY8
- SMR:   Q6MEY8
- STRING:   Q6MEY8
- GeneID:   2781312
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0137
- NMPDR:   fig|264201.1.peg.137
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q6MEY8
- ProtClustDB:   PRK09377
- BioCyc:   CPRO264201:PC0137-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31152; Mature: 31021

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVTPALIKELRERTGVGMGKCKEALEEANGDMELAIANLRKAGMASAVKKEGRETKEG
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCHHHCC
MIGTAENEKTIAIVEVNAETDFVVKNERFKEFLENIAREVANTNPSSLDAFLQQKYSKES
CCCCCCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
SLTVDQYRATIVQTIGENIQIKRIMTLQKSPERSFGIYSHLGGKIVTMVEITGSNQEEAL
CCCHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCHHHHCCCEEEEEEEEECCCHHHHH
AKDIAMHIAATAPDYLSPEKIPQEIITSEKDIAKGQIQGKPANIVDKIVEGKINAFYDTN
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCEEECCC
CLVRQKYIKDDSLSITDLVNQRSKVVGKELAVTNFIRWNVGQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
AAVTPALIKELRERTGVGMGKCKEALEEANGDMELAIANLRKAGMASAVKKEGRETKEG
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCHHHCC
MIGTAENEKTIAIVEVNAETDFVVKNERFKEFLENIAREVANTNPSSLDAFLQQKYSKES
CCCCCCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
SLTVDQYRATIVQTIGENIQIKRIMTLQKSPERSFGIYSHLGGKIVTMVEITGSNQEEAL
CCCHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCHHHHCCCEEEEEEEEECCCHHHHH
AKDIAMHIAATAPDYLSPEKIPQEIITSEKDIAKGQIQGKPANIVDKIVEGKINAFYDTN
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCEEECCC
CLVRQKYIKDDSLSITDLVNQRSKVVGKELAVTNFIRWNVGQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA