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The map label for this gene is kgd [H]

Identifier: 161598675

GI number: 161598675

Start: 970254

End: 973967

Strand: Reverse

Name: kgd [H]

Synonym: DIP1002

Alternate gene names: 161598675

Gene position: 973967-970254 (Counterclockwise)

Preceding gene: 38233598

Following gene: 38233594

Centisome position: 39.14

GC content: 57.4

Gene sequence:

>3714_bases
GTGAGCAGCGCTAGTACTTTCGGCCAGAACGATTGGCTGGTAGACGAGATGTTCCAGCAGTTCCAAAAGGATCCGCAGTC
CGTAGATAAGGAATGGCGCGACCTTTTCGAGAAGCAGGGTGCCCCGAGCACACCGGGAACTGAGGCTAAGAACACCTCCC
CACAGCCAGCCGCCCCCGCAAAGAAGCAACCAGCACCGGCCAAGAAGCCAGCACCAACTACGGCTTCTGCCCCAGCTTCC
ACCGAAGCTAAGGCTGCACCAAAGCCAGAGAACAAGAAGCCTGCCAAAAAACAGCAGCCTTCCCCACTCGAGCGCACAGG
CGAGCTGCCCGCAGCTGGTTCCTCCGCAATCAAGGGCATTTACAAGGCAATTGCTAAGAACATGGACGAGTCGCTCGAGG
TTCCTACCGCGACCACCGTTCGCGATATGCCAGTAAAGCTGATGTGGGAGAACCGCTCCATTATCAACGAGCACCTCAAG
CGCACCACCGGTGGCAAAGTCTCCTTTACCCACATCATCGGCTACGCAGTGGTCAAAGCAACCATGGCCCACCCCGATAT
GAACAACTACTACGAAGTTGTTGACGGCAAGCCAACTCTCAACACCCCAGAGCACATCAACATGGGTTTGGCTATCGACG
TCCAGCAAAAGTCCGGTGCCCGCGCACTGGTCGTTGCTGCCATTAAAGAAGCCGAAACGCTTTCCTTCGCCGAGTTCGTC
GCTAAGTACGAGGACATCGTGGCACGCTCCCGTGTGGGCAAGCTCACGATGGATGATTACTCCGGTGTGACCATCTCTTT
GACCAACCCAGGTGGCATTGGTACCCGTCACTCCGTACCTCGTCTTACCAAGGGCCAAGGCGCCATCATCGGCGTTGGTT
CCATGGATTACCCAGCTGAATTCGCAGGTGCATCCGCAGACCGCCTCGCAGAGCTAGGTGTTGGCCGCTTGGTCACCATC
ACCTCTACGTACGATCACCGCATCATTCAGGGTGCGGAATCCGGTGAATTCCTGCGCACCATGAGCCAGCTATTTATCGA
TGATGCCTTCTGGGATGAGATCTTCGAATCCATCGGTATCCCTTACGCACCGATGCGCTGGGCTTCTGATCTTTCTAACA
CGGGAATCGATAAGAACACCCGCGTGATGCAACTCATCGAGGCATACCGCTCCCGTGGACACCTCATTGCAGACACAAAC
CCATTGCGCTGGCACCAGCCAGGCATGCCAGTCCCAGACCACCGCGATCTAGACATCGCCACGCACGGTCTTACCCTGTG
GGACCTTGATCGATCTTTCAACGTTGGTGGCTTCGGCGGCAAGGAAACCATGACACTGCGCGAGGTGCTCGGTCGCCTCC
GCGCCGCCTACACCCTCAAAGTGGGCTCGGAATACACCCACATTCTCGACCGCGATGAACGCCTCTGGTTGCAAGATCGC
ATCGAAGCGGGCATGCCGAAGCCTTCCTACGCTGAGCAGAAGTACATCCTGCAGAAACTCAACGCGGCACAGGCTTTCGA
GGACTTCCTCCAAACCAAGTACGTTGGCCAAAAACGTTTCTCCCTAGAAGGCGCCGAGGCACTGATCCCGCTGATGGACT
CTGCCATCGACACCGCCGCAGGCCAAGGCCTCGACGAAGTTGTTATCGGTATGCCACACCGCGGCCGCCTCAATGTGCTG
GTCAACATCGTGGGCAAGCCACTTGCAACCGTATTCACCGAATTCGAAGGCCACATCGAGCCAAAGGCTGCCGGTGGATC
TGGCGACGTGAAGTACCACCTCGGTGCTGAGGGCACTCACATCCAGATGTTCGGCGACAACGAAATCAAGGTTTCGCTTG
CCGCTAACCCATCTCACCTCGAAGCAGTCGACCCCGTTATGGAAGGTATTGCCCGCGCAAAGCAAGACCTCCTCAACAAG
GGTGACTCCACTGACGGCTACTCCGTTGTTCCTATGATGTTGCACGGCGACGCTGCATTCGCAGGACTTGGCATCGTTCA
AGAAACCTTGAACCTCGCCCAGCTGCGTGGCTACACCGTCGGCGGCACCATTCACATCATCGTGAACAACCAGATCGGCT
TCACCACCACCCCAGACTCCGGCCGCTCTAGCCACTATGCCACCGACCTTGCCAAGGCCTACGGCTGCCCTGTCTTCCAC
GTCAACGGTGACGATCCAGAAGCAGTGGTATGGGTTGGACGCCTCGCTACCGAGTACCGTCGCCAATTCGGCAAAGACGT
CTTCATCGACATGATCTCCTACCGTCGTCGCGGCCACAACGAAGCCGATGACCCATCGATGACGCAGCCAGAGATGTACA
AGCTGATCGACGCCCGCAACACCGTGCGCGAACAGTACAAGGAAGACCTCCTAGGCCGTGGCGAGCTGACCACCGAGGAC
GCCGAAAAGGTACAGCGCGATTTCCACGACCAGATGGAATCCATCTTCAACGATGTCAAGGAAACCGAAAAGAAGCCATT
CGAGGCACAAGCTGGCATCACTTCCTCCCAAGAAGTTCCACACGGCCTTGAAACCAACATCACCCGTGAAGAACTCGTAG
AAATCGGTCAGGCCTACGCCACAGCACCAGAAAACTTCGAGTTCCACCAGCGCGTAGCACCAGTAGCAAAGAAGCGCCTC
GAGGCAGCTCAAAACGGTGGCATTGACTGGGGTTGGGGCGAGCTCATCGCCTTCGGCTCCCTCGCAGCAGGCGGCAAGTT
CGTTCGCCTCGCAGGTGAAGATTCCCGACGCGGCACCTTCACCCAGCGCCACGCAGTGGTCTACGATCCACGCACCGGTG
AAGAGTTCAACGGCCTCAACGACCTTGCTGAGCGCAAGGGCAACGGCGGTAAGTTCCTCGTGTACAACTCCGCCCTGACC
GAATACGCTGGCATGGGCTTCGAATACGGCTACTCCGTAGGTAACGAAGATGCCGTCGTCGCATGGGAAGCACAGTTCGG
TGACTTTGCCAACGGCGCCCAGACCATCATCGACGAATACATCTCGTCCGGTGAGGCCAAGTGGGGCCAGACGTCCTCCG
TGATCCTTCTTCTGCCACACGGCTATGAAGGACAGGGCCCTGACCACTCCTCCGCACGTATTGAGCGCTACCTGCAGCTC
TGCGCTGAAGGAACCATGACCGTGGCACAGCCGACCACCCCAGCCAACTACTTCCACCTCCTACGCCGCCACGTACTCGG
CGGACTGAAGCGACCACTCGTCGTATTCACGCCAAAGTCCATGCTGCGTATGAAGGCTGCAACCTCAAGCGTGGAAGACT
TCACCCAGATGAAGAAGTTCCAGTCCGTCATCAACGACCCACGCTTCGTTAACGGCGGATTGGACAAGAACAAGGTCAAG
AAGATCATGCTGGTTTCCGGCAAGCTCTACTACGACCTTGCTAAGCGAGCACAAAAAGACAAGCGTGACGACGTAGCCAT
CGTCCGCATCGAAATGCTCCACCCAATCCCATTCAACCGTCTCAAAGAAGCCTTCGACTTCTACCCGAACGCCGAAGAAA
TCCGCTTCTGCCAAGACGAACCAGCAAACCAAGGCCCATGGCCATTCATGCACGAGCACCTACCAGAGCTCATCCCAGGC
ATGCTGCCAATGAAGCGCGTCTCCCGTCGCGCACAGGCCTCCACCGCCACCGGCCTATCCAAGGTCCACGCAGTGGAACA
GCAGCACTTGCTCGACGAAGCATTCGCTGACTAA

Upstream 100 bases:

>100_bases
AGTTCACAGTTGGAGGAAGAAAACCGATAGCCTGTAGTGAAGCTATTACAGTGTGAATAGACGTTAGAAATCTCACAAAG
AAATGAGGCGAGCACCTGCA

Downstream 100 bases:

>100_bases
GAATTGAAAGGGCGGCCCCTCCTAGAGGGGCCGCCCTTTTGTTTGCTGTGCTTTCTACTCATCAAATAGTTTGTCATTGA
CAGCCGTTGCTGCACTGCCA

Product: alpha-ketoglutarate decarboxylase

Products: NA

Alternate protein names: Alpha-ketoglutarate dehydrogenase [H]

Number of amino acids: Translated: 1237; Mature: 1236

Protein sequence:

>1237_residues
MSSASTFGQNDWLVDEMFQQFQKDPQSVDKEWRDLFEKQGAPSTPGTEAKNTSPQPAAPAKKQPAPAKKPAPTTASAPAS
TEAKAAPKPENKKPAKKQQPSPLERTGELPAAGSSAIKGIYKAIAKNMDESLEVPTATTVRDMPVKLMWENRSIINEHLK
RTTGGKVSFTHIIGYAVVKATMAHPDMNNYYEVVDGKPTLNTPEHINMGLAIDVQQKSGARALVVAAIKEAETLSFAEFV
AKYEDIVARSRVGKLTMDDYSGVTISLTNPGGIGTRHSVPRLTKGQGAIIGVGSMDYPAEFAGASADRLAELGVGRLVTI
TSTYDHRIIQGAESGEFLRTMSQLFIDDAFWDEIFESIGIPYAPMRWASDLSNTGIDKNTRVMQLIEAYRSRGHLIADTN
PLRWHQPGMPVPDHRDLDIATHGLTLWDLDRSFNVGGFGGKETMTLREVLGRLRAAYTLKVGSEYTHILDRDERLWLQDR
IEAGMPKPSYAEQKYILQKLNAAQAFEDFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVL
VNIVGKPLATVFTEFEGHIEPKAAGGSGDVKYHLGAEGTHIQMFGDNEIKVSLAANPSHLEAVDPVMEGIARAKQDLLNK
GDSTDGYSVVPMMLHGDAAFAGLGIVQETLNLAQLRGYTVGGTIHIIVNNQIGFTTTPDSGRSSHYATDLAKAYGCPVFH
VNGDDPEAVVWVGRLATEYRRQFGKDVFIDMISYRRRGHNEADDPSMTQPEMYKLIDARNTVREQYKEDLLGRGELTTED
AEKVQRDFHDQMESIFNDVKETEKKPFEAQAGITSSQEVPHGLETNITREELVEIGQAYATAPENFEFHQRVAPVAKKRL
EAAQNGGIDWGWGELIAFGSLAAGGKFVRLAGEDSRRGTFTQRHAVVYDPRTGEEFNGLNDLAERKGNGGKFLVYNSALT
EYAGMGFEYGYSVGNEDAVVAWEAQFGDFANGAQTIIDEYISSGEAKWGQTSSVILLLPHGYEGQGPDHSSARIERYLQL
CAEGTMTVAQPTTPANYFHLLRRHVLGGLKRPLVVFTPKSMLRMKAATSSVEDFTQMKKFQSVINDPRFVNGGLDKNKVK
KIMLVSGKLYYDLAKRAQKDKRDDVAIVRIEMLHPIPFNRLKEAFDFYPNAEEIRFCQDEPANQGPWPFMHEHLPELIPG
MLPMKRVSRRAQASTATGLSKVHAVEQQHLLDEAFAD

Sequences:

>Translated_1237_residues
MSSASTFGQNDWLVDEMFQQFQKDPQSVDKEWRDLFEKQGAPSTPGTEAKNTSPQPAAPAKKQPAPAKKPAPTTASAPAS
TEAKAAPKPENKKPAKKQQPSPLERTGELPAAGSSAIKGIYKAIAKNMDESLEVPTATTVRDMPVKLMWENRSIINEHLK
RTTGGKVSFTHIIGYAVVKATMAHPDMNNYYEVVDGKPTLNTPEHINMGLAIDVQQKSGARALVVAAIKEAETLSFAEFV
AKYEDIVARSRVGKLTMDDYSGVTISLTNPGGIGTRHSVPRLTKGQGAIIGVGSMDYPAEFAGASADRLAELGVGRLVTI
TSTYDHRIIQGAESGEFLRTMSQLFIDDAFWDEIFESIGIPYAPMRWASDLSNTGIDKNTRVMQLIEAYRSRGHLIADTN
PLRWHQPGMPVPDHRDLDIATHGLTLWDLDRSFNVGGFGGKETMTLREVLGRLRAAYTLKVGSEYTHILDRDERLWLQDR
IEAGMPKPSYAEQKYILQKLNAAQAFEDFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVL
VNIVGKPLATVFTEFEGHIEPKAAGGSGDVKYHLGAEGTHIQMFGDNEIKVSLAANPSHLEAVDPVMEGIARAKQDLLNK
GDSTDGYSVVPMMLHGDAAFAGLGIVQETLNLAQLRGYTVGGTIHIIVNNQIGFTTTPDSGRSSHYATDLAKAYGCPVFH
VNGDDPEAVVWVGRLATEYRRQFGKDVFIDMISYRRRGHNEADDPSMTQPEMYKLIDARNTVREQYKEDLLGRGELTTED
AEKVQRDFHDQMESIFNDVKETEKKPFEAQAGITSSQEVPHGLETNITREELVEIGQAYATAPENFEFHQRVAPVAKKRL
EAAQNGGIDWGWGELIAFGSLAAGGKFVRLAGEDSRRGTFTQRHAVVYDPRTGEEFNGLNDLAERKGNGGKFLVYNSALT
EYAGMGFEYGYSVGNEDAVVAWEAQFGDFANGAQTIIDEYISSGEAKWGQTSSVILLLPHGYEGQGPDHSSARIERYLQL
CAEGTMTVAQPTTPANYFHLLRRHVLGGLKRPLVVFTPKSMLRMKAATSSVEDFTQMKKFQSVINDPRFVNGGLDKNKVK
KIMLVSGKLYYDLAKRAQKDKRDDVAIVRIEMLHPIPFNRLKEAFDFYPNAEEIRFCQDEPANQGPWPFMHEHLPELIPG
MLPMKRVSRRAQASTATGLSKVHAVEQQHLLDEAFAD
>Mature_1236_residues
SSASTFGQNDWLVDEMFQQFQKDPQSVDKEWRDLFEKQGAPSTPGTEAKNTSPQPAAPAKKQPAPAKKPAPTTASAPAST
EAKAAPKPENKKPAKKQQPSPLERTGELPAAGSSAIKGIYKAIAKNMDESLEVPTATTVRDMPVKLMWENRSIINEHLKR
TTGGKVSFTHIIGYAVVKATMAHPDMNNYYEVVDGKPTLNTPEHINMGLAIDVQQKSGARALVVAAIKEAETLSFAEFVA
KYEDIVARSRVGKLTMDDYSGVTISLTNPGGIGTRHSVPRLTKGQGAIIGVGSMDYPAEFAGASADRLAELGVGRLVTIT
STYDHRIIQGAESGEFLRTMSQLFIDDAFWDEIFESIGIPYAPMRWASDLSNTGIDKNTRVMQLIEAYRSRGHLIADTNP
LRWHQPGMPVPDHRDLDIATHGLTLWDLDRSFNVGGFGGKETMTLREVLGRLRAAYTLKVGSEYTHILDRDERLWLQDRI
EAGMPKPSYAEQKYILQKLNAAQAFEDFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLV
NIVGKPLATVFTEFEGHIEPKAAGGSGDVKYHLGAEGTHIQMFGDNEIKVSLAANPSHLEAVDPVMEGIARAKQDLLNKG
DSTDGYSVVPMMLHGDAAFAGLGIVQETLNLAQLRGYTVGGTIHIIVNNQIGFTTTPDSGRSSHYATDLAKAYGCPVFHV
NGDDPEAVVWVGRLATEYRRQFGKDVFIDMISYRRRGHNEADDPSMTQPEMYKLIDARNTVREQYKEDLLGRGELTTEDA
EKVQRDFHDQMESIFNDVKETEKKPFEAQAGITSSQEVPHGLETNITREELVEIGQAYATAPENFEFHQRVAPVAKKRLE
AAQNGGIDWGWGELIAFGSLAAGGKFVRLAGEDSRRGTFTQRHAVVYDPRTGEEFNGLNDLAERKGNGGKFLVYNSALTE
YAGMGFEYGYSVGNEDAVVAWEAQFGDFANGAQTIIDEYISSGEAKWGQTSSVILLLPHGYEGQGPDHSSARIERYLQLC
AEGTMTVAQPTTPANYFHLLRRHVLGGLKRPLVVFTPKSMLRMKAATSSVEDFTQMKKFQSVINDPRFVNGGLDKNKVKK
IMLVSGKLYYDLAKRAQKDKRDDVAIVRIEMLHPIPFNRLKEAFDFYPNAEEIRFCQDEPANQGPWPFMHEHLPELIPGM
LPMKRVSRRAQASTATGLSKVHAVEQQHLLDEAFAD

Specific function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components:2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2)

COG id: COG0567

COG function: function code C; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-ketoglutarate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI259013553, Length=908, Percent_Identity=40.5286343612335, Blast_Score=648, Evalue=0.0,
Organism=Homo sapiens, GI51873036, Length=907, Percent_Identity=40.4630650496141, Blast_Score=645, Evalue=0.0,
Organism=Homo sapiens, GI221316661, Length=903, Percent_Identity=38.8704318936877, Blast_Score=632, Evalue=0.0,
Organism=Homo sapiens, GI221316665, Length=891, Percent_Identity=38.8327721661055, Blast_Score=623, Evalue=1e-178,
Organism=Homo sapiens, GI221316669, Length=802, Percent_Identity=39.9002493765586, Blast_Score=594, Evalue=1e-169,
Organism=Homo sapiens, GI38788380, Length=881, Percent_Identity=37.0034052213394, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI51873038, Length=286, Percent_Identity=39.5104895104895, Blast_Score=192, Evalue=2e-48,
Organism=Escherichia coli, GI1786945, Length=883, Percent_Identity=44.2808607021518, Blast_Score=709, Evalue=0.0,
Organism=Escherichia coli, GI1786946, Length=211, Percent_Identity=27.0142180094787, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17542494, Length=923, Percent_Identity=40.9534127843987, Blast_Score=665, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72001668, Length=893, Percent_Identity=37.4020156774916, Blast_Score=557, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6322066, Length=978, Percent_Identity=39.0593047034765, Blast_Score=647, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320352, Length=321, Percent_Identity=23.98753894081, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665669, Length=896, Percent_Identity=39.5089285714286, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665673, Length=896, Percent_Identity=39.5089285714286, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665677, Length=896, Percent_Identity=39.5089285714286, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574592, Length=896, Percent_Identity=39.5089285714286, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574590, Length=906, Percent_Identity=39.2935982339956, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI161084450, Length=906, Percent_Identity=39.2935982339956, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI161084461, Length=850, Percent_Identity=40.1176470588235, Blast_Score=628, Evalue=1e-179,
Organism=Drosophila melanogaster, GI78706592, Length=911, Percent_Identity=37.7607025246981, Blast_Score=601, Evalue=1e-171,
Organism=Drosophila melanogaster, GI78706596, Length=911, Percent_Identity=37.7607025246981, Blast_Score=601, Evalue=1e-171,
Organism=Drosophila melanogaster, GI281365454, Length=911, Percent_Identity=37.7607025246981, Blast_Score=601, Evalue=1e-171,
Organism=Drosophila melanogaster, GI281365452, Length=911, Percent_Identity=37.7607025246981, Blast_Score=601, Evalue=1e-171,
Organism=Drosophila melanogaster, GI78706594, Length=933, Percent_Identity=36.8703108252948, Blast_Score=588, Evalue=1e-168,
Organism=Drosophila melanogaster, GI78706598, Length=933, Percent_Identity=36.8703108252948, Blast_Score=588, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24651589, Length=884, Percent_Identity=36.9909502262443, Blast_Score=536, Evalue=1e-152,
Organism=Drosophila melanogaster, GI161079314, Length=749, Percent_Identity=39.5193591455274, Blast_Score=508, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24651591, Length=749, Percent_Identity=39.5193591455274, Blast_Score=508, Evalue=1e-144,
Organism=Drosophila melanogaster, GI18859875, Length=243, Percent_Identity=24.6913580246914, Blast_Score=69, Evalue=3e-11,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001078
- InterPro:   IPR011603
- InterPro:   IPR023213
- InterPro:   IPR001017
- InterPro:   IPR005475 [H]

Pfam domain/function: PF00198 2-oxoacid_dh; PF00676 E1_dh; PF02779 Transket_pyr [H]

EC number: =1.2.4.2 [H]

Molecular weight: Translated: 136497; Mature: 136366

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASTFGQNDWLVDEMFQQFQKDPQSVDKEWRDLFEKQGAPSTPGTEAKNTSPQPAAPA
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
KKQPAPAKKPAPTTASAPASTEAKAAPKPENKKPAKKQQPSPLERTGELPAAGSSAIKGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHH
YKAIAKNMDESLEVPTATTVRDMPVKLMWENRSIINEHLKRTTGGKVSFTHIIGYAVVKA
HHHHHHCCHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
TMAHPDMNNYYEVVDGKPTLNTPEHINMGLAIDVQQKSGARALVVAAIKEAETLSFAEFV
HHCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHH
AKYEDIVARSRVGKLTMDDYSGVTISLTNPGGIGTRHSVPRLTKGQGAIIGVGSMDYPAE
HHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCHH
FAGASADRLAELGVGRLVTITSTYDHRIIQGAESGEFLRTMSQLFIDDAFWDEIFESIGI
HCCCCHHHHHHCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PYAPMRWASDLSNTGIDKNTRVMQLIEAYRSRGHLIADTNPLRWHQPGMPVPDHRDLDIA
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEE
THGLTLWDLDRSFNVGGFGGKETMTLREVLGRLRAAYTLKVGSEYTHILDRDERLWLQDR
ECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCHHHHHHCCCCHHHHHHH
IEAGMPKPSYAEQKYILQKLNAAQAFEDFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHH
GQGLDEVVIGMPHRGRLNVLVNIVGKPLATVFTEFEGHIEPKAAGGSGDVKYHLGAEGTH
CCCHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCE
IQMFGDNEIKVSLAANPSHLEAVDPVMEGIARAKQDLLNKGDSTDGYSVVPMMLHGDAAF
EEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHH
AGLGIVQETLNLAQLRGYTVGGTIHIIVNNQIGFTTTPDSGRSSHYATDLAKAYGCPVFH
HHHHHHHHHHHHHHHCCEEECCEEEEEEECCCCCEECCCCCCCCHHHHHHHHHHCCCEEE
VNGDDPEAVVWVGRLATEYRRQFGKDVFIDMISYRRRGHNEADDPSMTQPEMYKLIDARN
ECCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TVREQYKEDLLGRGELTTEDAEKVQRDFHDQMESIFNDVKETEKKPFEAQAGITSSQEVP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCC
HGLETNITREELVEIGQAYATAPENFEFHQRVAPVAKKRLEAAQNGGIDWGWGELIAFGS
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
LAAGGKFVRLAGEDSRRGTFTQRHAVVYDPRTGEEFNGLNDLAERKGNGGKFLVYNSALT
CCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCEEEEECCHHH
EYAGMGFEYGYSVGNEDAVVAWEAQFGDFANGAQTIIDEYISSGEAKWGQTSSVILLLPH
HHHCCCCHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECC
GYEGQGPDHSSARIERYLQLCAEGTMTVAQPTTPANYFHLLRRHVLGGLKRPLVVFTPKS
CCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHH
MLRMKAATSSVEDFTQMKKFQSVINDPRFVNGGLDKNKVKKIMLVSGKLYYDLAKRAQKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHEEEEECCHHHHHHHHHHHHC
KRDDVAIVRIEMLHPIPFNRLKEAFDFYPNAEEIRFCQDEPANQGPWPFMHEHLPELIPG
CCCCEEEEEEEEECCCCHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCHHHHHHHHHCCC
MLPMKRVSRRAQASTATGLSKVHAVEQQHLLDEAFAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSASTFGQNDWLVDEMFQQFQKDPQSVDKEWRDLFEKQGAPSTPGTEAKNTSPQPAAPA
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
KKQPAPAKKPAPTTASAPASTEAKAAPKPENKKPAKKQQPSPLERTGELPAAGSSAIKGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHH
YKAIAKNMDESLEVPTATTVRDMPVKLMWENRSIINEHLKRTTGGKVSFTHIIGYAVVKA
HHHHHHCCHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
TMAHPDMNNYYEVVDGKPTLNTPEHINMGLAIDVQQKSGARALVVAAIKEAETLSFAEFV
HHCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHH
AKYEDIVARSRVGKLTMDDYSGVTISLTNPGGIGTRHSVPRLTKGQGAIIGVGSMDYPAE
HHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCHH
FAGASADRLAELGVGRLVTITSTYDHRIIQGAESGEFLRTMSQLFIDDAFWDEIFESIGI
HCCCCHHHHHHCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PYAPMRWASDLSNTGIDKNTRVMQLIEAYRSRGHLIADTNPLRWHQPGMPVPDHRDLDIA
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEE
THGLTLWDLDRSFNVGGFGGKETMTLREVLGRLRAAYTLKVGSEYTHILDRDERLWLQDR
ECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCHHHHHHCCCCHHHHHHH
IEAGMPKPSYAEQKYILQKLNAAQAFEDFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHH
GQGLDEVVIGMPHRGRLNVLVNIVGKPLATVFTEFEGHIEPKAAGGSGDVKYHLGAEGTH
CCCHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCE
IQMFGDNEIKVSLAANPSHLEAVDPVMEGIARAKQDLLNKGDSTDGYSVVPMMLHGDAAF
EEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHH
AGLGIVQETLNLAQLRGYTVGGTIHIIVNNQIGFTTTPDSGRSSHYATDLAKAYGCPVFH
HHHHHHHHHHHHHHHCCEEECCEEEEEEECCCCCEECCCCCCCCHHHHHHHHHHCCCEEE
VNGDDPEAVVWVGRLATEYRRQFGKDVFIDMISYRRRGHNEADDPSMTQPEMYKLIDARN
ECCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TVREQYKEDLLGRGELTTEDAEKVQRDFHDQMESIFNDVKETEKKPFEAQAGITSSQEVP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCC
HGLETNITREELVEIGQAYATAPENFEFHQRVAPVAKKRLEAAQNGGIDWGWGELIAFGS
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
LAAGGKFVRLAGEDSRRGTFTQRHAVVYDPRTGEEFNGLNDLAERKGNGGKFLVYNSALT
CCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCEEEEECCHHH
EYAGMGFEYGYSVGNEDAVVAWEAQFGDFANGAQTIIDEYISSGEAKWGQTSSVILLLPH
HHHCCCCHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECC
GYEGQGPDHSSARIERYLQLCAEGTMTVAQPTTPANYFHLLRRHVLGGLKRPLVVFTPKS
CCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHH
MLRMKAATSSVEDFTQMKKFQSVINDPRFVNGGLDKNKVKKIMLVSGKLYYDLAKRAQKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHEEEEECCHHHHHHHHHHHHC
KRDDVAIVRIEMLHPIPFNRLKEAFDFYPNAEEIRFCQDEPANQGPWPFMHEHLPELIPG
CCCCEEEEEEEEECCCCHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCHHHHHHHHHCCC
MLPMKRVSRRAQASTATGLSKVHAVEQQHLLDEAFAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004499; 12948626 [H]