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The map label for this gene is argD [H]

Identifier: 161594055

GI number: 161594055

Start: 1599716

End: 1600930

Strand: Direct

Name: argD [H]

Synonym: CV_1496

Alternate gene names: 161594055

Gene position: 1599716-1600930 (Clockwise)

Preceding gene: 34496950

Following gene: 34496952

Centisome position: 33.67

GC content: 64.77

Gene sequence:

>1215_bases
ATGAGCAATTCGGTAACCCGCGCTGATTTCGACCAGGTCATGGTCCCCAACTACGGCCCGGCCGGCTTCATCCCGGTGCG
CGGCGAAGGCTCCCGCATCTGGGACCAGGACGGCCGCGAATTCGTCGATCTGGCCGGCGGCATCGCCGTCAACTCGCTGG
GCCATTGCCATCCGGAATTGGTGGCCGCGCTGACCGAGCAGGCGAACAAGCTGTGGCACGTGTCCAACGTGTTCACCAAT
GAGCCGGCGCTGAAGCTGGCCAGCCTGCTGGTGGAAAAGACCTTCGCCGAGCGCGTGTTCTTCTGCAACTCCGGCGCCGA
GGCCAACGAGGCCGCGTTCAAGCTGGCGCGCAAATACGCTCATGACAACTTCGGCGCGGACAAGAACCAGATCCTGTCCT
GCGTCAATTCCTTCCATGGCCGCACCCTGTTCACCGTCAGCGTGGGCGGCCAGCCCAAATACACCGAAGGCTTCGGCCCG
GTGCCGGGCGGCATCGATCATTTCGAATTCAACAATATCGAATCGCTGAAAGCAGCCATTTCCGACCGCACTTGCGCGGT
GGTGATCGAGCCCATCCAGGGCGAGAGCGGCGTGCTGCCGGCCGATCCGGCTTTCCTGAAGGCCGCGCGCGAGCTGTGCG
ACCAGCACAACGCGCTGCTGATCTTTGACGAAGTGCAAAGCGGCATGGGCCGCACCGGCGCACTGTACGCCTACCAGCAG
TACGGCGTGACGCCCGACATCCTGTCCTCGGCCAAGGGCATCGGCGGCGGCTTCCCGATCGGCGCGATGCTGACCACCGA
GAAAGTGGCCAAGAGCTTCGGCATCGGCAGCCACGGCTCCACTTACGGCGGCAACCCGCTGGCCTGTGCGGTGGCCCACA
AAGTGGTGTCCATCGTTAGCTCCCCCGAGGTGCTCGCCGGCGTCGAGGCGCGCCACAAGCGCCTGGTGGCCGGCCTGGAG
GCGATCAACGCCAAATACAAGGTGTTCAAGCAGGTGCGCGGCAAGGGCCTGTTGATCGGTTGCGTGCTGACCGACGAATA
CAACGGCCGCGCGCGCGAATTCCTGAAGGCTGCCGAGAAGCAGCAGCTGATGATTCTGGTGGCGGGCCTGAGCGTGCTGC
GCCTGGCGCCGTCGCTGGTGATCAGCGATGCGGACATCGCCGAGGGCCTGAAGCGCCTCGACGCCGCCATCGCCGATCTG
CAATCCGCCAAGTAA

Upstream 100 bases:

>100_bases
GTGACTTCTCGTCCGCTTCCTTTAGAATCGATCGAGCATGTAAAAACAGCCGCGCGCAAAAAGCGTTGGCGCACGACAGA
ACAAGGAAGGAAAACCATCA

Downstream 100 bases:

>100_bases
GCCCAGCAAGGCCGCGCCGCATGGCTCGCCATGCGGCTTCCCCGACCAAGACGCAAACGCCACGACCCCGCTCCGGCCGG
GTCGCGGCTGCGGCTGCGCC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSNSVTRADFDQVMVPNYGPAGFIPVRGEGSRIWDQDGREFVDLAGGIAVNSLGHCHPELVAALTEQANKLWHVSNVFTN
EPALKLASLLVEKTFAERVFFCNSGAEANEAAFKLARKYAHDNFGADKNQILSCVNSFHGRTLFTVSVGGQPKYTEGFGP
VPGGIDHFEFNNIESLKAAISDRTCAVVIEPIQGESGVLPADPAFLKAARELCDQHNALLIFDEVQSGMGRTGALYAYQQ
YGVTPDILSSAKGIGGGFPIGAMLTTEKVAKSFGIGSHGSTYGGNPLACAVAHKVVSIVSSPEVLAGVEARHKRLVAGLE
AINAKYKVFKQVRGKGLLIGCVLTDEYNGRAREFLKAAEKQQLMILVAGLSVLRLAPSLVISDADIAEGLKRLDAAIADL
QSAK

Sequences:

>Translated_404_residues
MSNSVTRADFDQVMVPNYGPAGFIPVRGEGSRIWDQDGREFVDLAGGIAVNSLGHCHPELVAALTEQANKLWHVSNVFTN
EPALKLASLLVEKTFAERVFFCNSGAEANEAAFKLARKYAHDNFGADKNQILSCVNSFHGRTLFTVSVGGQPKYTEGFGP
VPGGIDHFEFNNIESLKAAISDRTCAVVIEPIQGESGVLPADPAFLKAARELCDQHNALLIFDEVQSGMGRTGALYAYQQ
YGVTPDILSSAKGIGGGFPIGAMLTTEKVAKSFGIGSHGSTYGGNPLACAVAHKVVSIVSSPEVLAGVEARHKRLVAGLE
AINAKYKVFKQVRGKGLLIGCVLTDEYNGRAREFLKAAEKQQLMILVAGLSVLRLAPSLVISDADIAEGLKRLDAAIADL
QSAK
>Mature_403_residues
SNSVTRADFDQVMVPNYGPAGFIPVRGEGSRIWDQDGREFVDLAGGIAVNSLGHCHPELVAALTEQANKLWHVSNVFTNE
PALKLASLLVEKTFAERVFFCNSGAEANEAAFKLARKYAHDNFGADKNQILSCVNSFHGRTLFTVSVGGQPKYTEGFGPV
PGGIDHFEFNNIESLKAAISDRTCAVVIEPIQGESGVLPADPAFLKAARELCDQHNALLIFDEVQSGMGRTGALYAYQQY
GVTPDILSSAKGIGGGFPIGAMLTTEKVAKSFGIGSHGSTYGGNPLACAVAHKVVSIVSSPEVLAGVEARHKRLVAGLEA
INAKYKVFKQVRGKGLLIGCVLTDEYNGRAREFLKAAEKQQLMILVAGLSVLRLAPSLVISDADIAEGLKRLDAAIADLQ
SAK

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=34.2857142857143, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI13994255, Length=426, Percent_Identity=29.5774647887324, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.4515050167224, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=25.1798561151079, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=25.7831325301205, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=25.3846153846154, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=24.3436754176611, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI188536080, Length=436, Percent_Identity=22.9357798165138, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI38679950, Length=436, Percent_Identity=22.9357798165138, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI38679946, Length=436, Percent_Identity=22.9357798165138, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1789759, Length=402, Percent_Identity=60.9452736318408, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1788044, Length=396, Percent_Identity=59.3434343434343, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=35.6234096692112, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI145693181, Length=371, Percent_Identity=35.0404312668464, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=32.7586206896552, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786991, Length=301, Percent_Identity=34.8837209302326, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1786349, Length=333, Percent_Identity=29.1291291291291, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=34.7043701799486, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=415, Percent_Identity=31.3253012048193, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=267, Percent_Identity=34.8314606741573, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=433, Percent_Identity=28.6374133949192, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71981843, Length=170, Percent_Identity=32.3529411764706, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17541228, Length=434, Percent_Identity=23.7327188940092, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=38.1679389312977, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.8308457711443, Blast_Score=209, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=321, Percent_Identity=30.8411214953271, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=36.7609254498715, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=29.3144208037825, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=28.978622327791, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI21356575, Length=407, Percent_Identity=26.7813267813268, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=23.444976076555, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=23.444976076555, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=23.444976076555, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43034; Mature: 42902

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSVTRADFDQVMVPNYGPAGFIPVRGEGSRIWDQDGREFVDLAGGIAVNSLGHCHPEL
CCCCCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCHHH
VAALTEQANKLWHVSNVFTNEPALKLASLLVEKTFAERVFFCNSGAEANEAAFKLARKYA
HHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDNFGADKNQILSCVNSFHGRTLFTVSVGGQPKYTEGFGPVPGGIDHFEFNNIESLKAAI
CCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SDRTCAVVIEPIQGESGVLPADPAFLKAARELCDQHNALLIFDEVQSGMGRTGALYAYQQ
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCEEEEHHH
YGVTPDILSSAKGIGGGFPIGAMLTTEKVAKSFGIGSHGSTYGGNPLACAVAHKVVSIVS
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
SPEVLAGVEARHKRLVAGLEAINAKYKVFKQVRGKGLLIGCVLTDEYNGRAREFLKAAEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHH
QQLMILVAGLSVLRLAPSLVISDADIAEGLKRLDAAIADLQSAK
HHEEHHHHHHHHHHHCHHHEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNSVTRADFDQVMVPNYGPAGFIPVRGEGSRIWDQDGREFVDLAGGIAVNSLGHCHPEL
CCCCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCHHH
VAALTEQANKLWHVSNVFTNEPALKLASLLVEKTFAERVFFCNSGAEANEAAFKLARKYA
HHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDNFGADKNQILSCVNSFHGRTLFTVSVGGQPKYTEGFGPVPGGIDHFEFNNIESLKAAI
CCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SDRTCAVVIEPIQGESGVLPADPAFLKAARELCDQHNALLIFDEVQSGMGRTGALYAYQQ
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCEEEEHHH
YGVTPDILSSAKGIGGGFPIGAMLTTEKVAKSFGIGSHGSTYGGNPLACAVAHKVVSIVS
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
SPEVLAGVEARHKRLVAGLEAINAKYKVFKQVRGKGLLIGCVLTDEYNGRAREFLKAAEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHH
QQLMILVAGLSVLRLAPSLVISDADIAEGLKRLDAAIADLQSAK
HHEEHHHHHHHHHHHCHHHEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]