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The map label for this gene is argC

Identifier: 161579522

GI number: 161579522

Start: 1035848

End: 1036873

Strand: Reverse

Name: argC

Synonym: MJ1096

Alternate gene names: 161579522

Gene position: 1036873-1035848 (Counterclockwise)

Preceding gene: 15669285

Following gene: 15669283

Centisome position: 62.28

GC content: 33.82

Gene sequence:

>1026_bases
ATGAAAGAAGTTGCTATAATTGGGGCTACTGGCTATACTGGGGCAGAGTTATTGAGATTATTAGCAAATCATGAAAAAGT
TAATGTAACATATATAACCTCAAGAAAAGAAGCTGGAAAGCATGTTTTTAAAGTTCATCCTCATTTAAAAGGTATTGAAA
AGTATAAAAACCTATGTTTTACTGGAGATATTGATAAGGTTGATGCTTATTTGGTATTTACTGCAACTCCACACGGAGCT
TCAATGGATATAGTTCCAGATTTTATTGAGAGAGGGATGAAAGTTATTGACTTAAGTGGAGATTATAGATTTGAGGATTT
AAGCTTGTATGAAAAATACTATAAGATAAAACATAAAGGATTACCTGATGTAAAAATTGCTTATGGATTGCCAGAATTAC
ATAGAGAGGAAATAAAAGAAGCTCAACTTGTAGCAAATCCTGGATGTTTCCCAACTGGAGCTATTTTGGCAGTAGCTCCA
TTAGTTAAAGAGAATATTATAGAGGAAAGGATTATATTTGATTCAAAAACGGGAGTTAGTGGAGCTGGAATAAAGCCAAC
GGAAACAACCCACTTCCCAAATGTAAATGAAAATATAAACCCATACAAAATAACAACCCACAGACACACTCCAGAGATTG
AGAAGGAGTTAAAAAAGCTTGGAAAGGCTAAGGTTTCATTCACTCCTCACTTAGCTCCAATAACAAGAGGAATTTTAACA
ACTGCACACACATTCTTAGCTAAAGATGTTGATAGAGAGGAGATAATTAAGATTTATGAAAAATTCTATGGGAGTGAGGT
TTTTGTTAGGATATTTTCAGAAGAGATTCCAAAATTAACATGGGTTAGAGGAACAAACTTCTGTGATATCGGAGGATTTG
AGATTGATGAGCATGGTAGATTGGTAGTTATCTCAGCAATAGATAATTTAGTTAAAGGAGCGAGTGGGCAAGCAATACAA
AACATGAATATAATGTTTGGATTTGATGAAAAAGAGGGGTTATTTGATGTAGGGTTAAATCCATAA

Upstream 100 bases:

>100_bases
GAGAATTATAATTAAGTTAAGTCTGGAAATATTATTAATATTAATTAGGATATTTATTCCCAAAGAAAATCCTAATAATA
AAAAGAAAATTGGTGAAAGG

Downstream 100 bases:

>100_bases
TTATTTTTAATATTTTTTGGCGATGTATTAAGTATATTTTATCTTCAATATTAAGAAAATAACTCCTATTTTATAATTGC
TACCACTACAACAAGTTTCC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKEVAIIGATGYTGAELLRLLANHEKVNVTYITSRKEAGKHVFKVHPHLKGIEKYKNLCFTGDIDKVDAYLVFTATPHGA
SMDIVPDFIERGMKVIDLSGDYRFEDLSLYEKYYKIKHKGLPDVKIAYGLPELHREEIKEAQLVANPGCFPTGAILAVAP
LVKENIIEERIIFDSKTGVSGAGIKPTETTHFPNVNENINPYKITTHRHTPEIEKELKKLGKAKVSFTPHLAPITRGILT
TAHTFLAKDVDREEIIKIYEKFYGSEVFVRIFSEEIPKLTWVRGTNFCDIGGFEIDEHGRLVVISAIDNLVKGASGQAIQ
NMNIMFGFDEKEGLFDVGLNP

Sequences:

>Translated_341_residues
MKEVAIIGATGYTGAELLRLLANHEKVNVTYITSRKEAGKHVFKVHPHLKGIEKYKNLCFTGDIDKVDAYLVFTATPHGA
SMDIVPDFIERGMKVIDLSGDYRFEDLSLYEKYYKIKHKGLPDVKIAYGLPELHREEIKEAQLVANPGCFPTGAILAVAP
LVKENIIEERIIFDSKTGVSGAGIKPTETTHFPNVNENINPYKITTHRHTPEIEKELKKLGKAKVSFTPHLAPITRGILT
TAHTFLAKDVDREEIIKIYEKFYGSEVFVRIFSEEIPKLTWVRGTNFCDIGGFEIDEHGRLVVISAIDNLVKGASGQAIQ
NMNIMFGFDEKEGLFDVGLNP
>Mature_341_residues
MKEVAIIGATGYTGAELLRLLANHEKVNVTYITSRKEAGKHVFKVHPHLKGIEKYKNLCFTGDIDKVDAYLVFTATPHGA
SMDIVPDFIERGMKVIDLSGDYRFEDLSLYEKYYKIKHKGLPDVKIAYGLPELHREEIKEAQLVANPGCFPTGAILAVAP
LVKENIIEERIIFDSKTGVSGAGIKPTETTHFPNVNENINPYKITTHRHTPEIEKELKKLGKAKVSFTPHLAPITRGILT
TAHTFLAKDVDREEIIKIYEKFYGSEVFVRIFSEEIPKLTWVRGTNFCDIGGFEIDEHGRLVVISAIDNLVKGASGQAIQ
NMNIMFGFDEKEGLFDVGLNP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=39.4202898550725, Blast_Score=219, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6320913, Length=341, Percent_Identity=33.1378299120235, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_METJA (Q58496)

Other databases:

- EMBL:   L77117
- PIR:   G64436
- RefSeq:   NP_248089.2
- ProteinModelPortal:   Q58496
- SMR:   Q58496
- GeneID:   1451992
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1096
- NMPDR:   fig|243232.1.peg.1126
- TIGR:   MJ1096
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   MJAN243232:MJ_1096-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38172; Mature: 38172

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVAIIGATGYTGAELLRLLANHEKVNVTYITSRKEAGKHVFKVHPHLKGIEKYKNLCF
CCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEECCCHHHHHHHHCCEE
TGDIDKVDAYLVFTATPHGASMDIVPDFIERGMKVIDLSGDYRFEDLSLYEKYYKIKHKG
ECCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCC
LPDVKIAYGLPELHREEIKEAQLVANPGCFPTGAILAVAPLVKENIIEERIIFDSKTGVS
CCCEEEECCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
GAGIKPTETTHFPNVNENINPYKITTHRHTPEIEKELKKLGKAKVSFTPHLAPITRGILT
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHH
TAHTFLAKDVDREEIIKIYEKFYGSEVFVRIFSEEIPKLTWVRGTNFCDIGGFEIDEHGR
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCEEECCCEEECCCCC
LVVISAIDNLVKGASGQAIQNMNIMFGFDEKEGLFDVGLNP
EEEEHHHHHHHCCCCCCEEECCEEEEEECCCCCEEECCCCC
>Mature Secondary Structure
MKEVAIIGATGYTGAELLRLLANHEKVNVTYITSRKEAGKHVFKVHPHLKGIEKYKNLCF
CCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEECCCHHHHHHHHCCEE
TGDIDKVDAYLVFTATPHGASMDIVPDFIERGMKVIDLSGDYRFEDLSLYEKYYKIKHKG
ECCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCC
LPDVKIAYGLPELHREEIKEAQLVANPGCFPTGAILAVAPLVKENIIEERIIFDSKTGVS
CCCEEEECCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
GAGIKPTETTHFPNVNENINPYKITTHRHTPEIEKELKKLGKAKVSFTPHLAPITRGILT
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHH
TAHTFLAKDVDREEIIKIYEKFYGSEVFVRIFSEEIPKLTWVRGTNFCDIGGFEIDEHGR
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCEEECCCEEECCCCC
LVVISAIDNLVKGASGQAIQNMNIMFGFDEKEGLFDVGLNP
EEEEHHHHHHHCCCCCCEEECCEEEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087