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The map label for this gene is fmt [H]

Identifier: 161526292

GI number: 161526292

Start: 3410639

End: 3411622

Strand: Reverse

Name: fmt [H]

Synonym: Bmul_3123

Alternate gene names: 161526292

Gene position: 3411622-3410639 (Counterclockwise)

Preceding gene: 161526293

Following gene: 161526291

Centisome position: 98.93

GC content: 73.88

Gene sequence:

>984_bases
ATGACCCATACGTTGCGCGTGATTTTTGCCGGCACGCCGGAATTCGCCGCGGCCGCGCTGGCCGCGATCCACGACGCCGG
TTTCGCGGCGCCGCTCGTGCTCACGCAGCCCGACCGGCCCGCCGGGCGCGGCATGAAGCTGCAGGCGAGCGCCGTGAAGC
GCTACGCGCTCGAGCACGGGCTGCCCGTCGCGCAGCCGCCGTCGCTGCGCCGCGCCGGCAAGTATCCGGCCGAGGCTGCC
GAGGCGATTGAGCTGCTGCGCGCGACGCCGCACGACGTGATGGTCGTCGCCGCATACGGGCTGCTGCTGCCGCAGGAAGT
GCTCGACATTCCGCGCCACGGCTGCATCAACATCCATGCGTCGCTGCTGCCGCGCTGGCGCGGCGCCGCGCCGATCCACC
GTGCGATCGAGGCCGGCGATGCCGAAACGGGTGTCACGCTGATGCAGATGGACGCCGGGCTCGACACGGGCGCGATGATC
CAGGCATCGCGCATCGCGATTGCGCCCGACGATACGACGGCGACGCTGCACGACCGGCTCGCGGCCGACGGCGCGCGGCT
CATCGTCGACGCGCTCGCGCGGCTCGAACGCGACGGCACGCTCGCGGCGACGCCGCAGCCGGCCGACGGCGTGACCTACG
CAGAAAAGATCGGCAAGCACGAAGCCGCGCTCGACTGGCGCAAGCCCGCGGACGTGCTGGCGCGCCAGGTGCGCGCGTTC
GATCCGTTCCCCGGCGGCGTCGCGACGCTCGACGGCGCCGCGATCAAGATCTGGGCGGCCGAGCCCGCCACCGGGCGCGG
CGACGCGGCGCCCGGCACGATCGTCGAAGCGGCGCCGGACGGCGTCATCGTGGCGTGCGGCACCGGCGCGCTGCGCGTGA
CGCAGTTGCAGAAGCCGGGCGGCAAGCGGCTGCCGGCACGCGAATTCCTCGCCGGCTCGCCGCTCGCCGCAGGCCAGCGG
TTCGCATTGCCCGACGCGGGCTGA

Upstream 100 bases:

>100_bases
TACCTGTCGCCGCTCAAACAGAGCCGGATCAAGACGAAGATGAAGAAACTCGAACGCGCGATGTGACGCGCGTTCGCCGA
GACCGACCCCGAACGCTGTC

Downstream 100 bases:

>100_bases
GCGGCCGGCCAGACGCCATTCGACACGCTGCGCGGACCGCGCGCAATCGGCCGAACGGCCGAGTCGCGCGGCCTGTCCGG
CGCGCGTAGAATTTCCCGGC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTHTLRVIFAGTPEFAAAALAAIHDAGFAAPLVLTQPDRPAGRGMKLQASAVKRYALEHGLPVAQPPSLRRAGKYPAEAA
EAIELLRATPHDVMVVAAYGLLLPQEVLDIPRHGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMI
QASRIAIAPDDTTATLHDRLAADGARLIVDALARLERDGTLAATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
DPFPGGVATLDGAAIKIWAAEPATGRGDAAPGTIVEAAPDGVIVACGTGALRVTQLQKPGGKRLPAREFLAGSPLAAGQR
FALPDAG

Sequences:

>Translated_327_residues
MTHTLRVIFAGTPEFAAAALAAIHDAGFAAPLVLTQPDRPAGRGMKLQASAVKRYALEHGLPVAQPPSLRRAGKYPAEAA
EAIELLRATPHDVMVVAAYGLLLPQEVLDIPRHGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMI
QASRIAIAPDDTTATLHDRLAADGARLIVDALARLERDGTLAATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
DPFPGGVATLDGAAIKIWAAEPATGRGDAAPGTIVEAAPDGVIVACGTGALRVTQLQKPGGKRLPAREFLAGSPLAAGQR
FALPDAG
>Mature_326_residues
THTLRVIFAGTPEFAAAALAAIHDAGFAAPLVLTQPDRPAGRGMKLQASAVKRYALEHGLPVAQPPSLRRAGKYPAEAAE
AIELLRATPHDVMVVAAYGLLLPQEVLDIPRHGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMIQ
ASRIAIAPDDTTATLHDRLAADGARLIVDALARLERDGTLAATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAFD
PFPGGVATLDGAAIKIWAAEPATGRGDAAPGTIVEAAPDGVIVACGTGALRVTQLQKPGGKRLPAREFLAGSPLAAGQRF
ALPDAG

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=323, Percent_Identity=28.4829721362229, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI21614513, Length=321, Percent_Identity=27.1028037383178, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI164663775, Length=245, Percent_Identity=32.2448979591837, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1789683, Length=310, Percent_Identity=50.3225806451613, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1788589, Length=316, Percent_Identity=30.379746835443, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=327, Percent_Identity=26.2996941896024, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550868, Length=316, Percent_Identity=29.746835443038, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28571984, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585660, Length=256, Percent_Identity=28.125, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 33992; Mature: 33861

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTLRVIFAGTPEFAAAALAAIHDAGFAAPLVLTQPDRPAGRGMKLQASAVKRYALEHG
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEHHHHHHHHHHHHC
LPVAQPPSLRRAGKYPAEAAEAIELLRATPHDVMVVAAYGLLLPQEVLDIPRHGCINIHA
CCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHCCCCCEEEEHH
SLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMIQASRIAIAPDDTTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEECEEEECCCCCHHHHHHHH
AADGARLIVDALARLERDGTLAATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
HCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHC
DPFPGGVATLDGAAIKIWAAEPATGRGDAAPGTIVEAAPDGVIVACGTGALRVTQLQKPG
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCC
GKRLPAREFLAGSPLAAGQRFALPDAG
CCCCCHHHHHCCCCCCCCCEECCCCCC
>Mature Secondary Structure 
THTLRVIFAGTPEFAAAALAAIHDAGFAAPLVLTQPDRPAGRGMKLQASAVKRYALEHG
CCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEHHHHHHHHHHHHC
LPVAQPPSLRRAGKYPAEAAEAIELLRATPHDVMVVAAYGLLLPQEVLDIPRHGCINIHA
CCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHCCCCCEEEEHH
SLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMIQASRIAIAPDDTTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEECEEEECCCCCHHHHHHHH
AADGARLIVDALARLERDGTLAATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
HCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHC
DPFPGGVATLDGAAIKIWAAEPATGRGDAAPGTIVEAAPDGVIVACGTGALRVTQLQKPG
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCC
GKRLPAREFLAGSPLAAGQRFALPDAG
CCCCCHHHHHCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA