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The map label for this gene is atoC [H]

Identifier: 161526286

GI number: 161526286

Start: 3403606

End: 3404307

Strand: Reverse

Name: atoC [H]

Synonym: Bmul_3117

Alternate gene names: 161526286

Gene position: 3404307-3403606 (Counterclockwise)

Preceding gene: 161526287

Following gene: 161526285

Centisome position: 98.72

GC content: 68.38

Gene sequence:

>702_bases
ATGGCAACCATCCTGGTGGTAGATGATGAAATGGGCATCCGGGAATTGCTCTCGGAGATCCTCAGCGACGAAGGACACGT
CGTCGAGGCGGCGGAGAACGCGCAGGCTGCGCGGGAATACCGGCTGAATCAGGCGCCCGATCTCGTGCTGCTCGATATCT
GGATGCCGGATACCGACGGCGTCACGCTGCTCAAGGAATGGGCGGCTCAGGGCCTGCTGACGATGCCGGTCATCATGATG
TCCGGGCACGCGACGATCGACACGGCCGTCGAGGCGACGAAGATCGGCGCGCTCGATTTCCTCGAGAAGCCGATCGCGCT
GCAGAAGCTGCTGAAGGCCGTCGAGCACGGGCTCGCGCGCGGCGCGGCGCCGGTGTCCGCGAATGCGGCGGCGAAGGCCG
GCGCGGGGCAGGCGGCGGGGCCCGCGGCGGTCGCGTCGGCGGCCGCGCTGCCGACGCTCGGCGACGACGTCGCAGCGGCG
CTCGGCCTCGCGGGCCAGACGGCGGCGATTCCGTTCGACATTCCGCTGCGCGAAGCGCGCGATGCGTTCGAACGCGCGTA
CTTCGAATACCACCTCGCGCGCGAGAACGGCAGCATGACGCGCGTCGCGGAAAAGACGGGCCTCGAACGCACGCACCTGT
ATCGCAAGCTCAAGCAGCTCGGCGTCGAACTCGGCAAGAAGCCGTCCGAAGGCGCGGCGTAA

Upstream 100 bases:

>100_bases
CGGAGCGGCGCCCGCGGCGGCGTCGGCCGCCGGCAAGCCGGCCGCCGGACGGTCGGCCTCGACGAAGACAAAAGCAAGTG
AGCAGACAAAGGCAGCGTAA

Downstream 100 bases:

>100_bases
AAAATTTCACGAAAAGGGCTTGTACAGTTCAAAAGAGGTCGCTATACTCTCGTTTCTTCGTTGGCCCGGTAGCTCAGTTG
GTAGAGCAGCGGATTGAAAA

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MATILVVDDEMGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQGLLTMPVIMM
SGHATIDTAVEATKIGALDFLEKPIALQKLLKAVEHGLARGAAPVSANAAAKAGAGQAAGPAAVASAAALPTLGDDVAAA
LGLAGQTAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAA

Sequences:

>Translated_233_residues
MATILVVDDEMGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQGLLTMPVIMM
SGHATIDTAVEATKIGALDFLEKPIALQKLLKAVEHGLARGAAPVSANAAAKAGAGQAAGPAAVASAAALPTLGDDVAAA
LGLAGQTAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAA
>Mature_232_residues
ATILVVDDEMGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQGLLTMPVIMMS
GHATIDTAVEATKIGALDFLEKPIALQKLLKAVEHGLARGAAPVSANAAAKAGAGQAAGPAAVASAAALPTLGDDVAAAL
GLAGQTAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=40, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=39.6551724137931, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=36.2068965517241, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786784, Length=125, Percent_Identity=35.2, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786911, Length=135, Percent_Identity=31.1111111111111, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=31.0924369747899, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787229, Length=154, Percent_Identity=26.6233766233766, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24544; Mature: 24413

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILVVDDEMGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDG
CEEEEEECCCCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCC
VTLLKEWAAQGLLTMPVIMMSGHATIDTAVEATKIGALDFLEKPIALQKLLKAVEHGLAR
HHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GAAPVSANAAAKAGAGQAAGPAAVASAAALPTLGDDVAAALGLAGQTAAIPFDIPLREAR
CCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHH
DAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAA
HHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATILVVDDEMGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDG
EEEEEECCCCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCC
VTLLKEWAAQGLLTMPVIMMSGHATIDTAVEATKIGALDFLEKPIALQKLLKAVEHGLAR
HHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GAAPVSANAAAKAGAGQAAGPAAVASAAALPTLGDDVAAALGLAGQTAAIPFDIPLREAR
CCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHH
DAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAA
HHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]