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The map label for this gene is argB [H]

Identifier: 161526261

GI number: 161526261

Start: 3374655

End: 3375620

Strand: Direct

Name: argB [H]

Synonym: Bmul_3092

Alternate gene names: 161526261

Gene position: 3374655-3375620 (Clockwise)

Preceding gene: 161526257

Following gene: 161526262

Centisome position: 97.86

GC content: 63.04

Gene sequence:

>966_bases
ATGCTGCGCTGCGCCACTCCTGTACAATTCGCCCTGTTTCAACCGTTCCCAGCCAGAGCCGCCGCCATGTCCGAGCCCCT
CGACCTCTCGCAGATCGCCCCTACGCTGAAAGCAGAAATCCTTGCCGAGGCGCTGCCGTATATCCGCCGCTATCACGGCA
AGACCGTGGTCATCAAATACGGCGGCAATGCGATGACGGAAGAACGGCTCAAGCAGGGCTTCGCGCGCGACGTGATCCTG
CTGAAGCTGGTCGGCATCAATCCGGTGATCGTCCACGGCGGCGGTCCGCAGATCGATCACGCGCTGAAGAAGATCGGCAA
GGCGGGCACGTTCATCCAGGGCATGCGCGTGACCGACGAAGAGACGATGGAAGTCGTCGAATGGGTGCTGGGCGGTGAAG
TGCAGCAGGACATCGTGATGCTGATCAATCACTTCGGCGGCCATGCGGTCGGCCTGACCGGCAAGGACGGCGGCCTGATC
CATGCGCGCAAGCTGCTGATGCCGGACCGCGACAACCCGGGCGAGTACATCGACATCGGCCAGGTCGGCGAAGTCGAGGC
GATCAACCCGGCCGTCGTGAAGGCGCTGCAGGACGACGCGTTCATCCCCGTGATCTCGCCGATCGGCTTCGGCGAAGACG
GCCTGTCGTACAACATCAACGCGGATCTCGTCGCCGGCAAGCTGGCGACGGTGCTGAACGCCGAAAAGCTCGTGATGATG
ACCAACATCCCGGGCGTGATGGACAAGGAAGGCAACCTGCTGACCGATCTGTCCGCGCGCGAGATCGACGCGCTGTTCGA
GGACGGCACGATTTCCGGCGGCATGCTGCCGAAGATCTCGTCGGCGCTCGACGCAGCGAAGAGCGGCGTGAAGTCGGTCC
ATATCGTCGACGGCCGCATCGAGCATTCGGTGCTGCTCGAAATCCTGACCGAGCAGCCGTTCGGCACGATGATCCGCTCG
CATTGA

Upstream 100 bases:

>100_bases
CACGTCCAGCGCCGCGCGCAGGCCGCTCGGCCATGACTGGCGGGGCACCGCGCGTTCGGCGCGGCGCTCGGCACCGGCGG
TTCGGCCGACCCAAAAACCG

Downstream 100 bases:

>100_bases
GCGCGCGCCGCCCACCCTCCGGTATCGATCTGCCGGCGTCGCTGCGCCGCCGGCGCGTGTCTCGCAGCCGGCCGCGCGCC
GGCGCGCCGGTCTGGCTGTT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLRCATPVQFALFQPFPARAAAMSEPLDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVIL
LKLVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLI
HARKLLMPDRDNPGEYIDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLVMM
TNIPGVMDKEGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRS
H

Sequences:

>Translated_321_residues
MLRCATPVQFALFQPFPARAAAMSEPLDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVIL
LKLVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLI
HARKLLMPDRDNPGEYIDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLVMM
TNIPGVMDKEGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRS
H
>Mature_321_residues
MLRCATPVQFALFQPFPARAAAMSEPLDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVIL
LKLVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLI
HARKLLMPDRDNPGEYIDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLVMM
TNIPGVMDKEGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRS
H

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=283, Percent_Identity=27.9151943462898, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI145693208, Length=264, Percent_Identity=29.1666666666667, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=270, Percent_Identity=27.4074074074074, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 34501; Mature: 34501

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRCATPVQFALFQPFPARAAAMSEPLDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKY
CCCCCCCHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDE
CCCCCCHHHHHHHHHHHEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCEEECEECCCH
ETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGEYIDIG
HHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEHCCCCCCCCCCCEEECC
QVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLVMM
CCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHCCCEEEEE
TNIPGVMDKEGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRI
ECCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCH
EHSVLLEILTEQPFGTMIRSH
HHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MLRCATPVQFALFQPFPARAAAMSEPLDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKY
CCCCCCCHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDE
CCCCCCHHHHHHHHHHHEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCEEECEECCCH
ETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGEYIDIG
HHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEHCCCCCCCCCCCEEECC
QVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLVMM
CCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHCCCEEEEE
TNIPGVMDKEGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRI
ECCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCH
EHSVLLEILTEQPFGTMIRSH
HHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA