| Definition | Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010084 |
| Length | 3,448,466 |
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The map label for this gene is slt [H]
Identifier: 161526198
GI number: 161526198
Start: 3310848
End: 3312800
Strand: Reverse
Name: slt [H]
Synonym: Bmul_3029
Alternate gene names: 161526198
Gene position: 3312800-3310848 (Counterclockwise)
Preceding gene: 161526200
Following gene: 161526197
Centisome position: 96.07
GC content: 67.33
Gene sequence:
>1953_bases ATGTCGAACAGCCTTTTCCGAGTATATCGTGCGGTCGCGCTCGCGCTGTCGGCCGCCGCGCTCGTCGCGGGCACGGCCGC CTGTGCCGCCCCGAACGACGACACGCTGGCCGGGGACGACCAGATCTTCGTGCAGCTTCGCGAAGCGGCGCGCCGCAACG ACGCAGCGAAGGCTGCGCAGCTCGCCGCGATGATTCCGAACTATCCGGTGCCGTCGTACGTCGAGTATTTCCAGATCAAG CCGCAGCTGTTCGACTCGACGGGCCGCGCGCGCGTCGATGCGCCCGACGCGCCCGTGGTGTCGTTCCTGCAGCGCTACGA CGGGCAGGCGATCGCCGATCGCATGCGCAACGATTATCTGCTCGTGCTCGGCGCGCGCCACGACTGGCGCAATTTCGACG AGCAGTACAAGCGCTTCGTGCTCGACGACGACACGCAGGTCAAGTGCTATGCGCTCGAGTCGCGCGCGGCGCGCGGCGAG AACGTCGCCGATGCGGCGCGCGCGCTGCTCGTCGAGCCGAAGTATTACGGCGACGCGTGCGTCGATCTCATCACCGCGCT CGCGGTCAATCAGCAGTTCACGAGCGACGACGTGTGGCAGCAGGCGCGCTTCGCGTACGAGCAGAACTACACGTCGCTCG GCGGCAAGATCGTCGACGCGCTCGGCGCGCGCCCGGTCGGCTTCGATCAGGCGACGAGCGCGCCGCCGCTGTACCTCGCG CGCGGCGTCGGCGCCGACGCGGCCTCGCATCAGCTCGCGCTGATCGCGCTCGGCCGGATGGCGCGCAACGATCCGGACTC GGCGGCCGCGATGCTGACGTCGATCGCGCCGTCGCTGACGAAGCAGGAACAGGCGATCGCGTGGGGCGCAATCGGCTATC AGGGCGCGCTGAAGCGCTCGCCGCTCGCGTCGGTCTGGTATGCGAAGTCCGCGAACGCGCCGCTGTCGAATTCCGGCTAC GAATGGCGCACGCGCGCGGCGCTGCTCGCCGGCAACTGGCCGATGGTGCGCTGGTCGATCGAGCAGATGCCGCCGTCGCT GCGCGAAGATCCGGCATGGATCTACTGGCATGCGCGCGCGCTGAAGCAAAGCGGCGACACGCTGCAGGCGAATCAGGAAT TCGAGCAGGTCGCGGGCCAGTTCAACTTCTACGGGCAGCTCGCCGGCGAGGAGCTCGGCCAGCGCACGACGATTCCGCCG CGCACGCGCGTCAGCGACGCGGAGATCGACGCGATGAGCAAGGTGCCGGGCTTCGCGCTCGCGCAGCGCTTCTATTCGCT GAACCTGCGGCTCGAAGGCAATCGCGAATGGAACTGGCCGCTGCGCGGCATGACCGACCGTCAGTTGCTGGCAGCCGCCG AATACGGCAAGCGCATCGGGCTGCTCGACCGCACGGTCAATACGGCCGATCGCACGAAGGCCGAGCACGATTTCACGCTG CGCTATCCGTCGCCGTATCGCGACATCGTCGAGCGCTACGCGCAATCGACCGGCCTCGACATCGAATGGGCGTACGGGCT GATCCGTCAGGAATCGCGTTTCATCACGAGCGCGCGCTCGTCGGCGGGCGCCGGCGGGCTGATGCAGCTGATGCCGGCCA CGGCGCAGCTCGTCGCGAAGAAGCTCGGCATGGGCACGATCACGCGTGCGCAGATGCACGACATCGACACCAATATCCAG CTCGGCACCTGGTATCTGGCCGACATCTACAACAACTTCGACAGCTCGCCGGTGCTCGCGACGGCCGGCTACAACGCGGG CCCCGGCCGCCCGCGCCAATGGCGGCAGGTATTGACGCAGCCCGTCGAAGGCGCGATCTTCGCGGAAACGATCCCGTTCA ACGAGACGCGCGACTACGTGAAGAACGTGTTGTCGAACACCGTGTATTACGCGGCGTTGTTCGAGGGCAAACCGCAGTCG TTGAAGAAACGGCTGGGCATGATCTCGCCCTGA
Upstream 100 bases:
>100_bases TCGCGACGCGCGCCGGACAGCGTTTTGCGAAGCGCAACCTTCGGGTTCGGCACAGGGTTGCGTGCTATGCTTTCGCTCAA TTCGTGCTCCATTCAAAACG
Downstream 100 bases:
>100_bases TCCGCAACCTTCACACTGCCGCGCACGACGCGGCAGTGTCCTTTTTGAGGTTCCGACCATGGATGGCCAGACCGTCGCGC TGCTGGGCGGCACCGGCTTT
Product: lytic transglycosylase catalytic
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 650; Mature: 649
Protein sequence:
>650_residues MSNSLFRVYRAVALALSAAALVAGTAACAAPNDDTLAGDDQIFVQLREAARRNDAAKAAQLAAMIPNYPVPSYVEYFQIK PQLFDSTGRARVDAPDAPVVSFLQRYDGQAIADRMRNDYLLVLGARHDWRNFDEQYKRFVLDDDTQVKCYALESRAARGE NVADAARALLVEPKYYGDACVDLITALAVNQQFTSDDVWQQARFAYEQNYTSLGGKIVDALGARPVGFDQATSAPPLYLA RGVGADAASHQLALIALGRMARNDPDSAAAMLTSIAPSLTKQEQAIAWGAIGYQGALKRSPLASVWYAKSANAPLSNSGY EWRTRAALLAGNWPMVRWSIEQMPPSLREDPAWIYWHARALKQSGDTLQANQEFEQVAGQFNFYGQLAGEELGQRTTIPP RTRVSDAEIDAMSKVPGFALAQRFYSLNLRLEGNREWNWPLRGMTDRQLLAAAEYGKRIGLLDRTVNTADRTKAEHDFTL RYPSPYRDIVERYAQSTGLDIEWAYGLIRQESRFITSARSSAGAGGLMQLMPATAQLVAKKLGMGTITRAQMHDIDTNIQ LGTWYLADIYNNFDSSPVLATAGYNAGPGRPRQWRQVLTQPVEGAIFAETIPFNETRDYVKNVLSNTVYYAALFEGKPQS LKKRLGMISP
Sequences:
>Translated_650_residues MSNSLFRVYRAVALALSAAALVAGTAACAAPNDDTLAGDDQIFVQLREAARRNDAAKAAQLAAMIPNYPVPSYVEYFQIK PQLFDSTGRARVDAPDAPVVSFLQRYDGQAIADRMRNDYLLVLGARHDWRNFDEQYKRFVLDDDTQVKCYALESRAARGE NVADAARALLVEPKYYGDACVDLITALAVNQQFTSDDVWQQARFAYEQNYTSLGGKIVDALGARPVGFDQATSAPPLYLA RGVGADAASHQLALIALGRMARNDPDSAAAMLTSIAPSLTKQEQAIAWGAIGYQGALKRSPLASVWYAKSANAPLSNSGY EWRTRAALLAGNWPMVRWSIEQMPPSLREDPAWIYWHARALKQSGDTLQANQEFEQVAGQFNFYGQLAGEELGQRTTIPP RTRVSDAEIDAMSKVPGFALAQRFYSLNLRLEGNREWNWPLRGMTDRQLLAAAEYGKRIGLLDRTVNTADRTKAEHDFTL RYPSPYRDIVERYAQSTGLDIEWAYGLIRQESRFITSARSSAGAGGLMQLMPATAQLVAKKLGMGTITRAQMHDIDTNIQ LGTWYLADIYNNFDSSPVLATAGYNAGPGRPRQWRQVLTQPVEGAIFAETIPFNETRDYVKNVLSNTVYYAALFEGKPQS LKKRLGMISP >Mature_649_residues SNSLFRVYRAVALALSAAALVAGTAACAAPNDDTLAGDDQIFVQLREAARRNDAAKAAQLAAMIPNYPVPSYVEYFQIKP QLFDSTGRARVDAPDAPVVSFLQRYDGQAIADRMRNDYLLVLGARHDWRNFDEQYKRFVLDDDTQVKCYALESRAARGEN VADAARALLVEPKYYGDACVDLITALAVNQQFTSDDVWQQARFAYEQNYTSLGGKIVDALGARPVGFDQATSAPPLYLAR GVGADAASHQLALIALGRMARNDPDSAAAMLTSIAPSLTKQEQAIAWGAIGYQGALKRSPLASVWYAKSANAPLSNSGYE WRTRAALLAGNWPMVRWSIEQMPPSLREDPAWIYWHARALKQSGDTLQANQEFEQVAGQFNFYGQLAGEELGQRTTIPPR TRVSDAEIDAMSKVPGFALAQRFYSLNLRLEGNREWNWPLRGMTDRQLLAAAEYGKRIGLLDRTVNTADRTKAEHDFTLR YPSPYRDIVERYAQSTGLDIEWAYGLIRQESRFITSARSSAGAGGLMQLMPATAQLVAKKLGMGTITRAQMHDIDTNIQL GTWYLADIYNNFDSSPVLATAGYNAGPGRPRQWRQVLTQPVEGAIFAETIPFNETRDYVKNVLSNTVYYAALFEGKPQSL KKRLGMISP
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=647, Percent_Identity=25.5023183925811, Blast_Score=182, Evalue=6e-47,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 71924; Mature: 71793
Theoretical pI: Translated: 7.99; Mature: 7.99
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNSLFRVYRAVALALSAAALVAGTAACAAPNDDTLAGDDQIFVQLREAARRNDAAKAAQ CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH LAAMIPNYPVPSYVEYFQIKPQLFDSTGRARVDAPDAPVVSFLQRYDGQAIADRMRNDYL HHHHCCCCCCCHHHHHHCCCHHHHCCCCCEECCCCCCHHHHHHHHHCCHHHHHHHCCCEE LVLGARHDWRNFDEQYKRFVLDDDTQVKCYALESRAARGENVADAARALLVEPKYYGDAC EEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHH VDLITALAVNQQFTSDDVWQQARFAYEQNYTSLGGKIVDALGARPVGFDQATSAPPLYLA HHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE RGVGADAASHQLALIALGRMARNDPDSAAAMLTSIAPSLTKQEQAIAWGAIGYQGALKRS CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC PLASVWYAKSANAPLSNSGYEWRTRAALLAGNWPMVRWSIEQMPPSLREDPAWIYWHARA CCHHHEEECCCCCCCCCCCCCHHHEEEEEECCCCEEEEEHHHCCCCCCCCCCEEEEEHHH LKQSGDTLQANQEFEQVAGQFNFYGQLAGEELGQRTTIPPRTRVSDAEIDAMSKVPGFAL HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHH AQRFYSLNLRLEGNREWNWPLRGMTDRQLLAAAEYGKRIGLLDRTVNTADRTKAEHDFTL HHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHCCCCCCEEE RYPSPYRDIVERYAQSTGLDIEWAYGLIRQESRFITSARSSAGAGGLMQLMPATAQLVAK ECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH KLGMGTITRAQMHDIDTNIQLGTWYLADIYNNFDSSPVLATAGYNAGPGRPRQWRQVLTQ HHCCCCCCHHHHHCCCCCEEECCEEHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHC PVEGAIFAETIPFNETRDYVKNVLSNTVYYAALFEGKPQSLKKRLGMISP CCCCCEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCCCC >Mature Secondary Structure SNSLFRVYRAVALALSAAALVAGTAACAAPNDDTLAGDDQIFVQLREAARRNDAAKAAQ CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH LAAMIPNYPVPSYVEYFQIKPQLFDSTGRARVDAPDAPVVSFLQRYDGQAIADRMRNDYL HHHHCCCCCCCHHHHHHCCCHHHHCCCCCEECCCCCCHHHHHHHHHCCHHHHHHHCCCEE LVLGARHDWRNFDEQYKRFVLDDDTQVKCYALESRAARGENVADAARALLVEPKYYGDAC EEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHH VDLITALAVNQQFTSDDVWQQARFAYEQNYTSLGGKIVDALGARPVGFDQATSAPPLYLA HHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE RGVGADAASHQLALIALGRMARNDPDSAAAMLTSIAPSLTKQEQAIAWGAIGYQGALKRS CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC PLASVWYAKSANAPLSNSGYEWRTRAALLAGNWPMVRWSIEQMPPSLREDPAWIYWHARA CCHHHEEECCCCCCCCCCCCCHHHEEEEEECCCCEEEEEHHHCCCCCCCCCCEEEEEHHH LKQSGDTLQANQEFEQVAGQFNFYGQLAGEELGQRTTIPPRTRVSDAEIDAMSKVPGFAL HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHH AQRFYSLNLRLEGNREWNWPLRGMTDRQLLAAAEYGKRIGLLDRTVNTADRTKAEHDFTL HHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHCCCCCCEEE RYPSPYRDIVERYAQSTGLDIEWAYGLIRQESRFITSARSSAGAGGLMQLMPATAQLVAK ECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH KLGMGTITRAQMHDIDTNIQLGTWYLADIYNNFDSSPVLATAGYNAGPGRPRQWRQVLTQ HHCCCCCCHHHHHCCCCCEEECCEEHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHC PVEGAIFAETIPFNETRDYVKNVLSNTVYYAALFEGKPQSLKKRLGMISP CCCCCEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]