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The map label for this gene is ypdF [H]

Identifier: 161526193

GI number: 161526193

Start: 3304502

End: 3306352

Strand: Reverse

Name: ypdF [H]

Synonym: Bmul_3024

Alternate gene names: 161526193

Gene position: 3306352-3304502 (Counterclockwise)

Preceding gene: 161526195

Following gene: 161526189

Centisome position: 95.88

GC content: 69.26

Gene sequence:

>1851_bases
ATGATCGATCGACTGACATACAGCTTTTCCAGCCTCTCGCCGTATCAAGCTTCCGTTGCCGACACGCAGGCCGCGCTGTC
GCGCACACTCGACACGCTGCAGCTCGACGCGCTCGTCGTCACGTCGCAGGACGAATACGTGACCGAGTATCTGCCGCGCC
ACAACAATCCGCGCTACGCGCTGTCGGGCTTCGACGGCTCGGCCGGCTGCGGTGTGTTTCTCGGCGAAGCGGCCGCGCGT
GCGCTCGGCATGCCGCCGTTCGTGCTGTTCGTCGACGGTCGCTATCACCTGCAGGCCGAGCAGCAGTGCGATCCCGCGCG
CGTGCGCGTCGAGAAGCTCGGCCTCGATCGGACGATCTGGGCCGCGATCGCGGACTGGCTGGTCGCGCACGCGGCCCACG
TGCCGCGCATCGGCTACGATGGCTGGCGCGTCAGCGTCGGCCAGCGCGAGCGCCTGTTCGCCGCGACGCGCGACGCGGCG
TTGACGTGGACGAGCGTCGCGGATCGCGCCGTCGATCGCACGATCGCGCTGCCCGGCTGGCACGTCGAGCGGCCGATCTT
CGAGCTGCCGGAGTCGATGACGGGTGCGCGCGTCGCCGAGCACGTCGCGGCGCTGAACCGGCGGCTCGCCGCGCGGACCG
GCGCGGCCGACGGCAAGACCGCATTCGTCACCTGCGCGTCCGACGATCTCGCCTATCTGCTGAACAGCCGCGGCTACCAT
CTGCCGAACGCGTCGTCGCATCTGGGCTTCCTGTTCGTGATCGGCGAGCAGATCGTGCTGTTCCTGCCGGAAGGCTGCGA
TCGCTGTCCGGTCGAACTCGCGTCGTATCCGGCGCTGCACGTGATCCGGCGCGACTTCGGCGCACTCGAGCGCTTCGTTG
CGCAGTTCGCGGTCGAGCACGTCTGCTACGGCTTCGACGCGGTGAACTGCGCGCTCGCCGACAGCGTGCGCCGCGTCTGG
CCGCATGCGGCGCACATCGACTTCAATCCGGTCGAAGCGATGCGAGCCGCGAAGACGCCGGCCGTGCTCGACCGATTCCG
CGATGCGTTCGCGCGCAGTTCGGCGGCGATCGCCGAGACGATGCGCTGGGCGAAGGCCGGCGAGCCCGGCCGGCGGCACA
CCGAATACGATCTCGCGCGCGCGATCAACGACGCGTACGGCGCGCGCTCGGCCGTCGCGCTGACGTTTCCGTCGATCGCG
GCGAACGGCGCGAACAGCGCGCACGCGCATTACACGGCCGCGAGCGCCGACGTCGAACTGACCGAAGGCGAACTCGTGCT
GCTCGACAGCGGCGCGTACTACGAAGCGGGGTTCGCGACCGACTGCACGCGCGTCGTTCTGCGCCGCACGCGTGCGGACA
CGGTCGCGCAGCCGTGGCAGCGCGAGATCTACACGGTCGCGCTGAAGGCGTGCATCAAGGGGCTCGTCACGCATTACCCG
AAAGACGCGACGGGCGGCGACGTCGACGCGCTCGTGCGTCAGGTCTGCCGCGATCACGGCTACGACTACGGGCACGGCAC
CGGACACGGCGTCGGCATCCACGTGCACGAAGGCGGCGTGCGTTTCGCGCCGGGCGCGCCCTACGGGCTCGTACCGAACG
CCGTGATTTCGGTGGAGCCCGGCATCTACGTGCCGGGCAAGGGCGGCGTGCGGATCGAGAACATCGTCATCATCCGCCCG
AGCGAGCGCGAGCCGGACAAGGTGCGCTTCGAGAATCTCGTTGCGGTCGGCTACGACTGGGACCTGATCGATCTGGCGCT
GCTCGACGACGACGAGCGTGCGTATCTGCGCGACTACGAGCGGATGTGCGTGGAGCGCGGCACGCAGGTGACGGCGTGTC
CGTTGCTGTAA

Upstream 100 bases:

>100_bases
TGCATGCACGACGCCCGCCCGCCAGCCGGTTTCGCCGCATGCGAGCACAACGCGCACGCCGCAGCACGCGTGGCGATAAC
GACGACAGGACGACCCTTCG

Downstream 100 bases:

>100_bases
GTTTGTCGGGGTGCGGCTCGGCGCAGCCGCCGCGCGCGACGCGGCGCTCGCCGGCCGTCTCGGTGCATCAGCGCATCAGC
GCCGACACGCGTCCGTCCGG

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MIDRLTYSFSSLSPYQASVADTQAALSRTLDTLQLDALVVTSQDEYVTEYLPRHNNPRYALSGFDGSAGCGVFLGEAAAR
ALGMPPFVLFVDGRYHLQAEQQCDPARVRVEKLGLDRTIWAAIADWLVAHAAHVPRIGYDGWRVSVGQRERLFAATRDAA
LTWTSVADRAVDRTIALPGWHVERPIFELPESMTGARVAEHVAALNRRLAARTGAADGKTAFVTCASDDLAYLLNSRGYH
LPNASSHLGFLFVIGEQIVLFLPEGCDRCPVELASYPALHVIRRDFGALERFVAQFAVEHVCYGFDAVNCALADSVRRVW
PHAAHIDFNPVEAMRAAKTPAVLDRFRDAFARSSAAIAETMRWAKAGEPGRRHTEYDLARAINDAYGARSAVALTFPSIA
ANGANSAHAHYTAASADVELTEGELVLLDSGAYYEAGFATDCTRVVLRRTRADTVAQPWQREIYTVALKACIKGLVTHYP
KDATGGDVDALVRQVCRDHGYDYGHGTGHGVGIHVHEGGVRFAPGAPYGLVPNAVISVEPGIYVPGKGGVRIENIVIIRP
SEREPDKVRFENLVAVGYDWDLIDLALLDDDERAYLRDYERMCVERGTQVTACPLL

Sequences:

>Translated_616_residues
MIDRLTYSFSSLSPYQASVADTQAALSRTLDTLQLDALVVTSQDEYVTEYLPRHNNPRYALSGFDGSAGCGVFLGEAAAR
ALGMPPFVLFVDGRYHLQAEQQCDPARVRVEKLGLDRTIWAAIADWLVAHAAHVPRIGYDGWRVSVGQRERLFAATRDAA
LTWTSVADRAVDRTIALPGWHVERPIFELPESMTGARVAEHVAALNRRLAARTGAADGKTAFVTCASDDLAYLLNSRGYH
LPNASSHLGFLFVIGEQIVLFLPEGCDRCPVELASYPALHVIRRDFGALERFVAQFAVEHVCYGFDAVNCALADSVRRVW
PHAAHIDFNPVEAMRAAKTPAVLDRFRDAFARSSAAIAETMRWAKAGEPGRRHTEYDLARAINDAYGARSAVALTFPSIA
ANGANSAHAHYTAASADVELTEGELVLLDSGAYYEAGFATDCTRVVLRRTRADTVAQPWQREIYTVALKACIKGLVTHYP
KDATGGDVDALVRQVCRDHGYDYGHGTGHGVGIHVHEGGVRFAPGAPYGLVPNAVISVEPGIYVPGKGGVRIENIVIIRP
SEREPDKVRFENLVAVGYDWDLIDLALLDDDERAYLRDYERMCVERGTQVTACPLL
>Mature_616_residues
MIDRLTYSFSSLSPYQASVADTQAALSRTLDTLQLDALVVTSQDEYVTEYLPRHNNPRYALSGFDGSAGCGVFLGEAAAR
ALGMPPFVLFVDGRYHLQAEQQCDPARVRVEKLGLDRTIWAAIADWLVAHAAHVPRIGYDGWRVSVGQRERLFAATRDAA
LTWTSVADRAVDRTIALPGWHVERPIFELPESMTGARVAEHVAALNRRLAARTGAADGKTAFVTCASDDLAYLLNSRGYH
LPNASSHLGFLFVIGEQIVLFLPEGCDRCPVELASYPALHVIRRDFGALERFVAQFAVEHVCYGFDAVNCALADSVRRVW
PHAAHIDFNPVEAMRAAKTPAVLDRFRDAFARSSAAIAETMRWAKAGEPGRRHTEYDLARAINDAYGARSAVALTFPSIA
ANGANSAHAHYTAASADVELTEGELVLLDSGAYYEAGFATDCTRVVLRRTRADTVAQPWQREIYTVALKACIKGLVTHYP
KDATGGDVDALVRQVCRDHGYDYGHGTGHGVGIHVHEGGVRFAPGAPYGLVPNAVISVEPGIYVPGKGGVRIENIVIIRP
SEREPDKVRFENLVAVGYDWDLIDLALLDDDERAYLRDYERMCVERGTQVTACPLL

Specific function: Hydrolyzes the N-terminal methionine when the next amino acid is alanine, proline or serine. The substrate preference for methionyl aminopeptidase activity is Pro > Ala > Ser. Also able to hydrolyze the Xaa-Pro peptide bond when the first amino acid is al

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24 family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=603, Percent_Identity=27.363184079602, Blast_Score=186, Evalue=8e-47,
Organism=Homo sapiens, GI93141226, Length=603, Percent_Identity=25.8706467661692, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI264681565, Length=602, Percent_Identity=25.7475083056478, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1788728, Length=235, Percent_Identity=31.4893617021277, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17509539, Length=602, Percent_Identity=27.906976744186, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25149105, Length=610, Percent_Identity=23.4426229508197, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322999, Length=638, Percent_Identity=23.5109717868339, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17137632, Length=609, Percent_Identity=26.6009852216749, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI161078230, Length=620, Percent_Identity=23.8709677419355, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357287, Length=620, Percent_Identity=23.8709677419355, Blast_Score=102, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 67409; Mature: 67409

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRLTYSFSSLSPYQASVADTQAALSRTLDTLQLDALVVTSQDEYVTEYLPRHNNPRYA
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHCCCCCCCCEE
LSGFDGSAGCGVFLGEAAARALGMPPFVLFVDGRYHLQAEQQCDPARVRVEKLGLDRTIW
EECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEECHHCCCCHHHHHHHHHCCCHHHH
AAIADWLVAHAAHVPRIGYDGWRVSVGQRERLFAATRDAALTWTSVADRAVDRTIALPGW
HHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCCCCEEHHHHHHHHHHCEEECCCC
HVERPIFELPESMTGARVAEHVAALNRRLAARTGAADGKTAFVTCASDDLAYLLNSRGYH
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCC
LPNASSHLGFLFVIGEQIVLFLPEGCDRCPVELASYPALHVIRRDFGALERFVAQFAVEH
CCCCCCCCEEEEEEECEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VCYGFDAVNCALADSVRRVWPHAAHIDFNPVEAMRAAKTPAVLDRFRDAFARSSAAIAET
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MRWAKAGEPGRRHTEYDLARAINDAYGARSAVALTFPSIAANGANSAHAHYTAASADVEL
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCEEEECCCCEEE
TEGELVLLDSGAYYEAGFATDCTRVVLRRTRADTVAQPWQREIYTVALKACIKGLVTHYP
ECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
KDATGGDVDALVRQVCRDHGYDYGHGTGHGVGIHVHEGGVRFAPGAPYGLVPNAVISVEP
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEECC
GIYVPGKGGVRIENIVIIRPSEREPDKVRFENLVAVGYDWDLIDLALLDDDERAYLRDYE
CEEECCCCCEEEEEEEEEECCCCCCCCEEECCEEEECCCCCEEEEEEECCCCHHHHHHHH
RMCVERGTQVTACPLL
HHHHHCCCCEEECCCC
>Mature Secondary Structure
MIDRLTYSFSSLSPYQASVADTQAALSRTLDTLQLDALVVTSQDEYVTEYLPRHNNPRYA
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHCCCCCCCCEE
LSGFDGSAGCGVFLGEAAARALGMPPFVLFVDGRYHLQAEQQCDPARVRVEKLGLDRTIW
EECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEECHHCCCCHHHHHHHHHCCCHHHH
AAIADWLVAHAAHVPRIGYDGWRVSVGQRERLFAATRDAALTWTSVADRAVDRTIALPGW
HHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCCCCEEHHHHHHHHHHCEEECCCC
HVERPIFELPESMTGARVAEHVAALNRRLAARTGAADGKTAFVTCASDDLAYLLNSRGYH
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCC
LPNASSHLGFLFVIGEQIVLFLPEGCDRCPVELASYPALHVIRRDFGALERFVAQFAVEH
CCCCCCCCEEEEEEECEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VCYGFDAVNCALADSVRRVWPHAAHIDFNPVEAMRAAKTPAVLDRFRDAFARSSAAIAET
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MRWAKAGEPGRRHTEYDLARAINDAYGARSAVALTFPSIAANGANSAHAHYTAASADVEL
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCEEEECCCCEEE
TEGELVLLDSGAYYEAGFATDCTRVVLRRTRADTVAQPWQREIYTVALKACIKGLVTHYP
ECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
KDATGGDVDALVRQVCRDHGYDYGHGTGHGVGIHVHEGGVRFAPGAPYGLVPNAVISVEP
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEECC
GIYVPGKGGVRIENIVIIRPSEREPDKVRFENLVAVGYDWDLIDLALLDDDERAYLRDYE
CEEECCCCCEEEEEEEEEECCCCCCCCEEECCEEEECCCCCEEEEEEECCCCHHHHHHHH
RMCVERGTQVTACPLL
HHHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]