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The map label for this gene is argM [C]

Identifier: 161526158

GI number: 161526158

Start: 3268833

End: 3270260

Strand: Direct

Name: argM [C]

Synonym: Bmul_2989

Alternate gene names: 161526158

Gene position: 3268833-3270260 (Clockwise)

Preceding gene: 161526157

Following gene: 161526159

Centisome position: 94.79

GC content: 66.04

Gene sequence:

>1428_bases
ATGACCTATCGCAACGAATCCGCGTGGATCCAGCCCGCCGCACCGGCGGCCCGCTCGACGCAGGCGCGCTCGACCGCCGA
ATACCGCGCGCTCGACGCCGCGCACCACATCCATCCGTTCTCCGACATGGGTGCGCTGAATCGCGCGGGCAGCCGCGTGA
TCGTGAAGGCCGACGGCGTCTATCTGTGGGACTCCGACGGCAACAAGATCATCGACGGCATGGCCGGGCTCTGGTGCGTG
AACGTCGGCTACGGCCGCAAGGAGCTGGCCGACGCCGCCTATCGCCAGTTGCAGGAACTGCCGTTCTACAACACGTTCTT
CAAGACCACGCATCCGCCCGTGATCGAACTCTCGGCAATGCTGGCCGAAGTCACGCCGCCCGGCTTCAACCACTTCTTCT
ATTGCAACAGCGGCTCGGAAGGCAACGATACCGTGCTGCGCGTCGTGCATCAGTACTGGCGCGTGCAGGGCAAGCCGCAG
AAGAAGTACGTGATCTCGCGCAAGAACGGCTATCACGGCTCGACGATCGCGGGCGGCACGCTCGGTGGCATGGGCTACAT
GCACGAGCAGATGCCGTCGAAGGTCGAGCACATCGTCCATATCGATCAGCCGTATTTCTTCGGCGAAGCGCAGCCGGGCG
AGACGCCCGAAGCGTTCGGCCTCGCGCGTGCGCAGCAGCTCGAGGCGAAGATTCTCGAGCTCGGCGCGGAGAACGTCGCG
GCATTCATCGGCGAGCCGTTCCAGGGCGCGGGCGGCGTGATCTTTCCGCCGTCGACGTACTGGCCGGAAATCCAGCGGAT
CTGCCGCAAGTACGACATCCTGCTCGTCGCCGACGAAGTGATCGGCGGCTTCGGCCGTACCGGCGAATGGTTCGCGCATC
AGCACTTCGGCTTCGAACCCGATCTGATCACGATGGCCAAGGGGCTCACGTCGGGCTACGTGCCGATGGGCGCGGTCGGC
ATTCACGAGCGCGTCGCACGGCCGATCATCGACAACGGCGAATTCAATCACGGGCTCACGTACTCGGGGCATCCGGTCGC
CGCGGCGGTGGCGGTCGCGAACCTGAAGCTGCTGCGCGACGAGGGGATCGTCGAGCGCGTGAAGCGCGACACAGGCCCGT
ACTTCCAGGCACTGATGCGCGAGACGTTCGCGCGTCATCCGATCGTCGGCGAAGTGCACGGCCACGGGCTCGTCGCGAGC
CTGCAGCTCGCCGAGGCGCCGGCCGAACGCCGCCGCTTCGCGAACGGCGGCGACGTCGGCACGATCTGCCGCGACTTCTG
CTTCAACGGCAACCTGATCATGCGCGCGACCGGCGACCGGATGCTGCTGTCGCCGCCGCTCGTGATCTCGCGGCAGGAAA
TCGATGAACTCGTGTCGAAGGCGAAGCGGGCCGTCGATGCGACCGCCCAGCAGCTGGGCCTTTCGTAA

Upstream 100 bases:

>100_bases
GAGACCGAATACGAAGCGTTCTTCCGCGTGATCAGCTCGTGGGAACGCCGTCATCTGCTGCTGCACGTGTAAGCGCGCAC
AACCGCAATCCGGAGGAAAC

Downstream 100 bases:

>100_bases
CGGCTTTGCCTACAGGTGTGCGGCGGGCGCCGCACGCCGCCACAACCAGGGGAACTCCACCATGCGTGCTCGCTTTCTTC
GTCAAGCCTGCTCCGCCGCT

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTYRNESAWIQPAAPAARSTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKIIDGMAGLWCV
NVGYGRKELADAAYRQLQELPFYNTFFKTTHPPVIELSAMLAEVTPPGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGKPQ
KKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQPGETPEAFGLARAQQLEAKILELGAENVA
AFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAVG
IHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKRDTGPYFQALMRETFARHPIVGEVHGHGLVAS
LQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKRAVDATAQQLGLS

Sequences:

>Translated_475_residues
MTYRNESAWIQPAAPAARSTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKIIDGMAGLWCV
NVGYGRKELADAAYRQLQELPFYNTFFKTTHPPVIELSAMLAEVTPPGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGKPQ
KKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQPGETPEAFGLARAQQLEAKILELGAENVA
AFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAVG
IHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKRDTGPYFQALMRETFARHPIVGEVHGHGLVAS
LQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKRAVDATAQQLGLS
>Mature_474_residues
TYRNESAWIQPAAPAARSTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKIIDGMAGLWCVN
VGYGRKELADAAYRQLQELPFYNTFFKTTHPPVIELSAMLAEVTPPGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGKPQK
KYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQPGETPEAFGLARAQQLEAKILELGAENVAA
FIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAVGI
HERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKRDTGPYFQALMRETFARHPIVGEVHGHGLVASL
QLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKRAVDATAQQLGLS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=439, Percent_Identity=26.4236902050114, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI24119277, Length=362, Percent_Identity=29.2817679558011, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI37574042, Length=379, Percent_Identity=28.4960422163588, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=376, Percent_Identity=28.7234042553192, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=26.463700234192, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI226442709, Length=332, Percent_Identity=28.3132530120482, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI284507298, Length=261, Percent_Identity=29.8850574712644, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI188536080, Length=430, Percent_Identity=23.7209302325581, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI38679950, Length=430, Percent_Identity=23.7209302325581, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI38679946, Length=430, Percent_Identity=23.7209302325581, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1788044, Length=403, Percent_Identity=28.287841191067, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=26.3414634146341, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1786991, Length=453, Percent_Identity=29.1390728476821, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789759, Length=415, Percent_Identity=26.5060240963855, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789016, Length=362, Percent_Identity=26.2430939226519, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787560, Length=363, Percent_Identity=28.9256198347107, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=427, Percent_Identity=26.6978922716628, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=371, Percent_Identity=26.9541778975741, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=28.5714285714286, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25144274, Length=267, Percent_Identity=31.0861423220974, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=432, Percent_Identity=24.7685185185185, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=456, Percent_Identity=26.9736842105263, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324386, Length=477, Percent_Identity=26.6247379454927, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=26.046511627907, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357415, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.9655172413793, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=28.5035629453682, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=25.5172413793103, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI281366494, Length=351, Percent_Identity=23.9316239316239, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24667139, Length=351, Percent_Identity=23.9316239316239, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24667143, Length=351, Percent_Identity=23.9316239316239, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 52195; Mature: 52064

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRNESAWIQPAAPAARSTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGV
CCCCCCCCEECCCCCCHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCE
YLWDSDGNKIIDGMAGLWCVNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPVIELSAM
EEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHH
LAEVTPPGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGKPQKKYVISRKNGYHGSTIAGGT
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCC
LGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQPGETPEAFGLARAQQLEAKILELGAENVA
CCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
AFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEP
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCC
DLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRD
CHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EGIVERVKRDTGPYFQALMRETFARHPIVGEVHGHGLVASLQLAEAPAERRRFANGGDVG
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHCCHHHHHCCCCCCHH
TICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKRAVDATAQQLGLS
HHHHHHHCCCCEEEEECCCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYRNESAWIQPAAPAARSTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGV
CCCCCCCEECCCCCCHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCE
YLWDSDGNKIIDGMAGLWCVNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPVIELSAM
EEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHH
LAEVTPPGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGKPQKKYVISRKNGYHGSTIAGGT
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCC
LGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQPGETPEAFGLARAQQLEAKILELGAENVA
CCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
AFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEP
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCC
DLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRD
CHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EGIVERVKRDTGPYFQALMRETFARHPIVGEVHGHGLVASLQLAEAPAERRRFANGGDVG
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHCCHHHHHCCCCCCHH
TICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKRAVDATAQQLGLS
HHHHHHHCCCCEEEEECCCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]