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The map label for this gene is yjcC [H]

Identifier: 161526135

GI number: 161526135

Start: 3246965

End: 3248806

Strand: Direct

Name: yjcC [H]

Synonym: Bmul_2966

Alternate gene names: 161526135

Gene position: 3246965-3248806 (Clockwise)

Preceding gene: 161526134

Following gene: 161526136

Centisome position: 94.16

GC content: 70.58

Gene sequence:

>1842_bases
ATGCCCGCGCCCCCTCCCGCTTCCGCTGCCGCCGGCAGCACCTCGCGCCTGATCGCGGATCGCGCGCTCGCCGCCGTGTT
CCAGCCGATCGTCGACCTCGGCTCGGGCACCGTCATCGGCTACGAGGGGCTGATCCGCGGGCCGCACGGCACCGAGCTCG
AGCCGCCTGCCGCGTTGTTCGCGCAGGCCGCGCGCGAGGGCGAGACGCTCGCGCTCGAACAGGCGGCCGCGCTCACCTGC
CTCGACGCATTCGCGGCGCTCGGCTGCGACGGCAAGCTGTTCCTCAATTTCAGCGCGGGCACGATCCTGCAGCTCGCGCG
CGAACGCGAGCGCGCCCGCATGCTGCTCGGCCGCGCGCGGGTCGGCGCCGAGCGCATCGTGATCGAGCTGACCGAGCAGA
ACGCGACGACCGACGTCGCGCACATCGTGCCGGCGATCGCGTCGCTGCGCGATGCGGGCATCCAGTTCGCGCTCGACGAC
TACGGCACCGCGAACGCGAGCATGAACCTCTGGCTGCGCCTGCACCCGGACGTCGTGAAGATCGACCGCTTCTTCATCCA
CGACATCGCGCGCGACCCGCTCAAGTTCGAAGCCGTGAAGGCGATGCAGCATTTCGCACATGCGAGCGGCGCGAAACTGA
TCGCCGAAGGCATCGAGAACGAATGCGACCTGATCGTCGTACGCGACATGGGCATCTGCTGCGTGCAGGGCTTCCTGCTC
GGCCGCCCGAACGCGCGGCCTTCGCGCGTCGTCGCGGCGGCCGCGCGCGAAGCGATCCGCACGCCGCACATCGCCGTGTT
CCCCGGCGCGACGCGCATCGCGCGGCCGGCCGGCACGATCGCCTCGAAGATGCTCGTGCCGGCGCCGGCACTGCCGCGCG
ACGCGACCAGCAACGACGTGCTGGACCTGTTCAACCGGATGCCCGACCTGCACGCGGTCGCGCTCGTCGAGCGCGGGCGG
CCCGTCGCGCTGGTCAACCGCCGCGGCTTCATCGACCGCTTCGCGCTGCCGTACCACCGCGAGGTGTTCGGCAAGAAGCC
GTGCCTGCAGTTCGCGAACGACGCGCCGCTGATGATCGAGAACTCGACCACCTTCGAGCAGCTCGCGATGCTGCTCGCGA
GCCATGATCAGCGCTATCTGGCGGACGGCTTCGTGATCACCGAGCACGGCCGCTACGTCGGGCTCGGCACGGGCGAAAGC
CTCGTGCGCGCGGTGACCGAGATGCGCATCGAGGCCGCACGCTACGCGAACCCGTTGACGTTCCTGCCCGGCAACATCCC
GATCAGCGCGCACATCGACCGCCTGCTTGCGCGCGACGCCGGCTTTCACGCGTGCTACGTCGACCTGAACCAATTCAAGC
CCTTCAACGACCAGTACGGCTACTGGCAAGGCGACGAGGTGCTGAAGTTCGCCGCGACGGTGCTGGCCGGCGTCTGCGAT
CCGCAGCGCGACTTTCTCGGGCACGTCGGCGGCGACGATTTCCTCGTGCTGTTCCAGCGCGACGACTGGCGATCGCGCGC
GCTCGCCGCGATCGAGCGCTTCAATCAGGGCGCGCAGCTGTTCTATACGCAGGCCGACCGGCAGGCAGGCGGCCTGCGCG
GCGAGGATCGCCACGGCAACCCTGCGTTCTTCGGTTTCGTGACGATGGCGATCGGCGCAGTCAGCGTACCGGCCGGCGCA
CACGGCGCGAAGCGCTATGGCAGCGACGAGATCGCGTCGGTCGCCGCGCTCGCGAAACGGCGGGCGAAACAACAGCCGGG
CGGGCTGGCGGTGGTCGACCTCGATGCGGGCCGCGCGGCGCTGCGGGAGCGCGGCGAGCCGCCCGGCGCGAGCGCGGGCT
GA

Upstream 100 bases:

>100_bases
CAATGCACCAACATCGCGCGTCGCGTCACACAATCTTCATTCAACTCTGCGCGCGCGCTGCCGTTAAGTCGTGGGTCCCG
TCGCTTCGGCTGCCACGCTC

Downstream 100 bases:

>100_bases
ATCGCGCGGGGCGAGGGCTCGGGTACGTGTCGGCCTGGCGCCTGCTGCGTTGCCGGCTTGTCTGGCCGCTCTCCGGATCG
CGCTACGCAGGCGACCTTCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MPAPPPASAAAGSTSRLIADRALAAVFQPIVDLGSGTVIGYEGLIRGPHGTELEPPAALFAQAAREGETLALEQAAALTC
LDAFAALGCDGKLFLNFSAGTILQLARERERARMLLGRARVGAERIVIELTEQNATTDVAHIVPAIASLRDAGIQFALDD
YGTANASMNLWLRLHPDVVKIDRFFIHDIARDPLKFEAVKAMQHFAHASGAKLIAEGIENECDLIVVRDMGICCVQGFLL
GRPNARPSRVVAAAAREAIRTPHIAVFPGATRIARPAGTIASKMLVPAPALPRDATSNDVLDLFNRMPDLHAVALVERGR
PVALVNRRGFIDRFALPYHREVFGKKPCLQFANDAPLMIENSTTFEQLAMLLASHDQRYLADGFVITEHGRYVGLGTGES
LVRAVTEMRIEAARYANPLTFLPGNIPISAHIDRLLARDAGFHACYVDLNQFKPFNDQYGYWQGDEVLKFAATVLAGVCD
PQRDFLGHVGGDDFLVLFQRDDWRSRALAAIERFNQGAQLFYTQADRQAGGLRGEDRHGNPAFFGFVTMAIGAVSVPAGA
HGAKRYGSDEIASVAALAKRRAKQQPGGLAVVDLDAGRAALRERGEPPGASAG

Sequences:

>Translated_613_residues
MPAPPPASAAAGSTSRLIADRALAAVFQPIVDLGSGTVIGYEGLIRGPHGTELEPPAALFAQAAREGETLALEQAAALTC
LDAFAALGCDGKLFLNFSAGTILQLARERERARMLLGRARVGAERIVIELTEQNATTDVAHIVPAIASLRDAGIQFALDD
YGTANASMNLWLRLHPDVVKIDRFFIHDIARDPLKFEAVKAMQHFAHASGAKLIAEGIENECDLIVVRDMGICCVQGFLL
GRPNARPSRVVAAAAREAIRTPHIAVFPGATRIARPAGTIASKMLVPAPALPRDATSNDVLDLFNRMPDLHAVALVERGR
PVALVNRRGFIDRFALPYHREVFGKKPCLQFANDAPLMIENSTTFEQLAMLLASHDQRYLADGFVITEHGRYVGLGTGES
LVRAVTEMRIEAARYANPLTFLPGNIPISAHIDRLLARDAGFHACYVDLNQFKPFNDQYGYWQGDEVLKFAATVLAGVCD
PQRDFLGHVGGDDFLVLFQRDDWRSRALAAIERFNQGAQLFYTQADRQAGGLRGEDRHGNPAFFGFVTMAIGAVSVPAGA
HGAKRYGSDEIASVAALAKRRAKQQPGGLAVVDLDAGRAALRERGEPPGASAG
>Mature_612_residues
PAPPPASAAAGSTSRLIADRALAAVFQPIVDLGSGTVIGYEGLIRGPHGTELEPPAALFAQAAREGETLALEQAAALTCL
DAFAALGCDGKLFLNFSAGTILQLARERERARMLLGRARVGAERIVIELTEQNATTDVAHIVPAIASLRDAGIQFALDDY
GTANASMNLWLRLHPDVVKIDRFFIHDIARDPLKFEAVKAMQHFAHASGAKLIAEGIENECDLIVVRDMGICCVQGFLLG
RPNARPSRVVAAAAREAIRTPHIAVFPGATRIARPAGTIASKMLVPAPALPRDATSNDVLDLFNRMPDLHAVALVERGRP
VALVNRRGFIDRFALPYHREVFGKKPCLQFANDAPLMIENSTTFEQLAMLLASHDQRYLADGFVITEHGRYVGLGTGESL
VRAVTEMRIEAARYANPLTFLPGNIPISAHIDRLLARDAGFHACYVDLNQFKPFNDQYGYWQGDEVLKFAATVLAGVCDP
QRDFLGHVGGDDFLVLFQRDDWRSRALAAIERFNQGAQLFYTQADRQAGGLRGEDRHGNPAFFGFVTMAIGAVSVPAGAH
GAKRYGSDEIASVAALAKRRAKQQPGGLAVVDLDAGRAALRERGEPPGASAG

Specific function: Overexpression reduces biofilm formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=243, Percent_Identity=27.9835390946502, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788849, Length=149, Percent_Identity=32.8859060402685, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082096, Length=209, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081743, Length=235, Percent_Identity=28.0851063829787, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786507, Length=225, Percent_Identity=28, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI226510982, Length=238, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081845, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081980, Length=120, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787055, Length=228, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787541, Length=223, Percent_Identity=27.3542600896861, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788502, Length=222, Percent_Identity=26.5765765765766, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 66030; Mature: 65899

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPPPASAAAGSTSRLIADRALAAVFQPIVDLGSGTVIGYEGLIRGPHGTELEPPAALF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCCHHHHH
AQAAREGETLALEQAAALTCLDAFAALGCDGKLFLNFSAGTILQLARERERARMLLGRAR
HHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
VGAERIVIELTEQNATTDVAHIVPAIASLRDAGIQFALDDYGTANASMNLWLRLHPDVVK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCHHH
IDRFFIHDIARDPLKFEAVKAMQHFAHASGAKLIAEGIENECDLIVVRDMGICCVQGFLL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
GRPNARPSRVVAAAAREAIRTPHIAVFPGATRIARPAGTIASKMLVPAPALPRDATSNDV
CCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHCCCHHHHHHHHCCCCCCCCCCCCCHHH
LDLFNRMPDLHAVALVERGRPVALVNRRGFIDRFALPYHREVFGKKPCLQFANDAPLMIE
HHHHHCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHCCCCHHHHCCCCCEEEE
NSTTFEQLAMLLASHDQRYLADGFVITEHGRYVGLGTGESLVRAVTEMRIEAARYANPLT
CCCCHHHHHHHHHHCCCCEECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCCCE
FLPGNIPISAHIDRLLARDAGFHACYVDLNQFKPFNDQYGYWQGDEVLKFAATVLAGVCD
ECCCCCCHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PQRDFLGHVGGDDFLVLFQRDDWRSRALAAIERFNQGAQLFYTQADRQAGGLRGEDRHGN
CCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
PAFFGFVTMAIGAVSVPAGAHGAKRYGSDEIASVAALAKRRAKQQPGGLAVVDLDAGRAA
CHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
LRERGEPPGASAG
HHHCCCCCCCCCC
>Mature Secondary Structure 
PAPPPASAAAGSTSRLIADRALAAVFQPIVDLGSGTVIGYEGLIRGPHGTELEPPAALF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCCHHHHH
AQAAREGETLALEQAAALTCLDAFAALGCDGKLFLNFSAGTILQLARERERARMLLGRAR
HHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
VGAERIVIELTEQNATTDVAHIVPAIASLRDAGIQFALDDYGTANASMNLWLRLHPDVVK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCHHH
IDRFFIHDIARDPLKFEAVKAMQHFAHASGAKLIAEGIENECDLIVVRDMGICCVQGFLL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
GRPNARPSRVVAAAAREAIRTPHIAVFPGATRIARPAGTIASKMLVPAPALPRDATSNDV
CCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHCCCHHHHHHHHCCCCCCCCCCCCCHHH
LDLFNRMPDLHAVALVERGRPVALVNRRGFIDRFALPYHREVFGKKPCLQFANDAPLMIE
HHHHHCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHCCCCHHHHCCCCCEEEE
NSTTFEQLAMLLASHDQRYLADGFVITEHGRYVGLGTGESLVRAVTEMRIEAARYANPLT
CCCCHHHHHHHHHHCCCCEECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCCCE
FLPGNIPISAHIDRLLARDAGFHACYVDLNQFKPFNDQYGYWQGDEVLKFAATVLAGVCD
ECCCCCCHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PQRDFLGHVGGDDFLVLFQRDDWRSRALAAIERFNQGAQLFYTQADRQAGGLRGEDRHGN
CCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
PAFFGFVTMAIGAVSVPAGAHGAKRYGSDEIASVAALAKRRAKQQPGGLAVVDLDAGRAA
CHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
LRERGEPPGASAG
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]