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The map label for this gene is dapA [H]

Identifier: 161526110

GI number: 161526110

Start: 3218785

End: 3219684

Strand: Direct

Name: dapA [H]

Synonym: Bmul_2941

Alternate gene names: 161526110

Gene position: 3218785-3219684 (Clockwise)

Preceding gene: 161526106

Following gene: 161526112

Centisome position: 93.34

GC content: 72.89

Gene sequence:

>900_bases
ATGCACACATCACCCCGTTTTGAAGGTATCTGGCTGCCGATCGTCACGCCGTTTCACCGCGGCGACGTCGATCATCGCGC
GCTCGCGCGCCTGGCGCGGCACTATGCGGCCGCCGGCATCGCAGGCTTCGTCGCGGGCGCGACGACCGGCGAAGGCGTGC
TGCTCGATGCACGCGAGCAGGACGCCGTGTTCGCGACGCTGCGCGACGCGGTGCCGGACCGGCCGATCGTCGTCGGGCTG
ACCGCGAGCGCAACGCACGCTGCGGCCGCGCGCGCCCGCGAACTGGCGGCGCTGCGCCCGGACGGCCTGCTCGTCACGCC
GCCCGTCTACGTGCGGCCGACGCAGGACGGCATTCGGCGCCACGTCGAAGCGATCGTCGAGGCGGCCGACCTGCCGGTGC
TCGTCTACAACATTCCGTACCGCACCGGCGTGAACGTCGAACTCGACACGCTGCAGGCGCTCGCGCGCGATGCGCGCGTG
GCCGGCATCAAGGAATGCGGCTGCACGCTCGAGCGGATGAGCCGGCTCGTGCACGAGACGCCGCTCGCGGTGCTGTCCGG
CGACGACAACCAGAACTTCGCCGCGCTCTGCGCGGGCGCGCACGGGACGATCGCGAGCAGCGCGCACGTGCTGCCCGAAT
GGCATGTGCGGATGCACGCGCTGCTGCGCGACGGCCGTCTCGCCGACGCGCGGCGTATCGCGGTCGCGTTGCAGCCGCTC
GTCGCCGCGCTGTTCGCCGAGCCGAATCCGGCGCCCGTGAAGGCCGTGCTGGCCGCGCAAGGCTGGTGCGACGACGGCTT
GCGTCTGCCGTTCGTGCCGGCGAGCGACGCGCTGTGCGCGCGGCTGCGCACGCTGTGCGCGGAACTCGACGCGCATGCGC
CGGCGAGCGCGATGGCGTAG

Upstream 100 bases:

>100_bases
GATGCCCGCAGGTCGTTTCTTTTCCTTGCTCGCACGCCTCGCACCGGCATGGCGCCGGCGGAACGGTTGTCTCCCTCCCG
TTCTCACCATGAGGCTTTGC

Downstream 100 bases:

>100_bases
CGCGGCGCGGCGCGCATCGAATCGGCGAGGCGCCGTGCGCGCTCGCCGCTGCACGCTACGCGGCGAGTGCGGCCGCCGCC
GGATGTGTCGCTTCGCGCAC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MHTSPRFEGIWLPIVTPFHRGDVDHRALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAVPDRPIVVGL
TASATHAAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVEAADLPVLVYNIPYRTGVNVELDTLQALARDARV
AGIKECGCTLERMSRLVHETPLAVLSGDDNQNFAALCAGAHGTIASSAHVLPEWHVRMHALLRDGRLADARRIAVALQPL
VAALFAEPNPAPVKAVLAAQGWCDDGLRLPFVPASDALCARLRTLCAELDAHAPASAMA

Sequences:

>Translated_299_residues
MHTSPRFEGIWLPIVTPFHRGDVDHRALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAVPDRPIVVGL
TASATHAAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVEAADLPVLVYNIPYRTGVNVELDTLQALARDARV
AGIKECGCTLERMSRLVHETPLAVLSGDDNQNFAALCAGAHGTIASSAHVLPEWHVRMHALLRDGRLADARRIAVALQPL
VAALFAEPNPAPVKAVLAAQGWCDDGLRLPFVPASDALCARLRTLCAELDAHAPASAMA
>Mature_299_residues
MHTSPRFEGIWLPIVTPFHRGDVDHRALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAVPDRPIVVGL
TASATHAAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVEAADLPVLVYNIPYRTGVNVELDTLQALARDARV
AGIKECGCTLERMSRLVHETPLAVLSGDDNQNFAALCAGAHGTIASSAHVLPEWHVRMHALLRDGRLADARRIAVALQPL
VAALFAEPNPAPVKAVLAAQGWCDDGLRLPFVPASDALCARLRTLCAELDAHAPASAMA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=232, Percent_Identity=25.8620689655172, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1788823, Length=276, Percent_Identity=35.5072463768116, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789620, Length=297, Percent_Identity=26.2626262626263, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082415, Length=253, Percent_Identity=25.6916996047431, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786463, Length=238, Percent_Identity=26.890756302521, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31787; Mature: 31787

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSPRFEGIWLPIVTPFHRGDVDHRALARLARHYAAAGIAGFVAGATTGEGVLLDAREQ
CCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
DAVFATLRDAVPDRPIVVGLTASATHAAAARARELAALRPDGLLVTPPVYVRPTQDGIRR
CHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHH
HVEAIVEAADLPVLVYNIPYRTGVNVELDTLQALARDARVAGIKECGCTLERMSRLVHET
HHHHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHC
PLAVLSGDDNQNFAALCAGAHGTIASSAHVLPEWHVRMHALLRDGRLADARRIAVALQPL
CEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VAALFAEPNPAPVKAVLAAQGWCDDGLRLPFVPASDALCARLRTLCAELDAHAPASAMA
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MHTSPRFEGIWLPIVTPFHRGDVDHRALARLARHYAAAGIAGFVAGATTGEGVLLDAREQ
CCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
DAVFATLRDAVPDRPIVVGLTASATHAAAARARELAALRPDGLLVTPPVYVRPTQDGIRR
CHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHH
HVEAIVEAADLPVLVYNIPYRTGVNVELDTLQALARDARVAGIKECGCTLERMSRLVHET
HHHHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHC
PLAVLSGDDNQNFAALCAGAHGTIASSAHVLPEWHVRMHALLRDGRLADARRIAVALQPL
CEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VAALFAEPNPAPVKAVLAAQGWCDDGLRLPFVPASDALCARLRTLCAELDAHAPASAMA
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA