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The map label for this gene is hemA [H]

Identifier: 161526056

GI number: 161526056

Start: 3151861

End: 3153159

Strand: Direct

Name: hemA [H]

Synonym: Bmul_2887

Alternate gene names: 161526056

Gene position: 3151861-3153159 (Clockwise)

Preceding gene: 161526055

Following gene: 161526057

Centisome position: 91.4

GC content: 67.13

Gene sequence:

>1299_bases
ATGCAACTCCTCACGATCGGAATCAACCACCACACTGCGCCAGTCGCCTTGCGCGAACGCGTGGCGTTTCCGCTCGAGCA
GATCAAGCCGGCTCTCGTCACGTTCAAGAACGTGTTCCTCGGCCCGCAGGCGCCGAACGCGCCCGAAGCGGCGATCCTGT
CCACCTGCAACCGCACCGAGCTCTACTGCGCGACCGACGATCGCGCGGCGCGCGATGCCGCGATCCGCTGGCTGTCCGAC
TATCACCGGATTCCGGTCGATGAACTGGCGCCGCACGTCTATGCGCTGCCGCAATCCGAAGCGGTCCGGCACGCATTTCG
CGTCGCCTCGGGCCTCGATTCGATGGTGCTCGGCGAAACGCAGATCCTCGGCCAGATGAAGGATGCGGTGCGTACCGCGT
CCGAAGCCGGCGCGCTCGGCACCTACCTGAACCAGCTGTTCCAGCGCACGTTCGCGGTTGCGAAGGAAGTGCGCGGCACG
ACGGAAATCGGCGCGCAGTCGGTGTCGATGGCGGCCGCCGCGGTACGCCTCGCGCAGCGGATCTTCGAAAAGGTGTCGGA
CCAGCGCGTGCTGTTCATCGGCGCGGGCGAAATGATCGAGCTCTGCGCGACGCACTTCGCCGCGCAAGGCCCGCGCGAGC
TCGTCGTCGCGAACCGCACGGCCGAGCGCGGCCAGCGGCTCGCCGAACGCTTCAACGGCCGCGCGATGCCGCTGTCGGAC
CTGCCGGCGCGGATGCAGGAATTCGACATCATCGTGTCGTGCACGGCGTCGACGCTGCCGATCATCGGCCTCGGCGCGGT
CGAGCGTGCCGTGAAGGCGCGCCGCCACCGTCCGATCTTCATGGTCGATCTCGCCGTGCCGCGCGACATCGAGCCCGAAG
TCAGCAAGCTGAAGGACGTGTTCCTGTACACCGTCGACGATCTCGGCGCGATCGTGCGCGAAGGCAACGCATCGCGTCAG
GCGGCGGTCGCGCAGGCCGAAGCGATCATCGAGACGCGCGTGCAGAATTTCATGCAATGGCTCGATACGCGCAGCGTCGT
GCCCGTGATCCGTCATATGCACACGCAGGCCGACGCGCTGCGCCGCCTGGAAGTCGAGAAGGCGCAGAAAATGCTCGCTC
GCGGCGACGACCCGGCCGCCGTGCTCGAAGCGCTGTCGCAGGCGCTGACCAACAAGCTGATCCACGGCCCGACGAGTGCG
CTCAACCGCGTGAACGGCGCCGATCGCGATTCGCTGATCGAGCTGATGCGCGGTTTCTACCAGCACGCGCCGCGCTCCAA
CGATCAGTCCGGCCACTAG

Upstream 100 bases:

>100_bases
AGCCCCCAAATCGCCGCCCGCGCATCGCGGACGCCCGCTACAGCGCAGGTGAGCAATCCGCCGAGACGCTATAATATGCG
GCTAAACGATAGCCCTCGAT

Downstream 100 bases:

>100_bases
CGCCGGCCGATCGCACTGCCGCCGGCCGTCGGCCGGCCTATCCTTTCCGAATACTCCTTGCCCGGGAGCGCCGCTCCACA
CCATGAAGACGAGCATGCAA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNAPEAAILSTCNRTELYCATDDRAARDAAIRWLSD
YHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRGT
TEIGAQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLSD
LPARMQEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVSKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRLEVEKAQKMLARGDDPAAVLEALSQALTNKLIHGPTSA
LNRVNGADRDSLIELMRGFYQHAPRSNDQSGH

Sequences:

>Translated_432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNAPEAAILSTCNRTELYCATDDRAARDAAIRWLSD
YHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRGT
TEIGAQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLSD
LPARMQEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVSKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRLEVEKAQKMLARGDDPAAVLEALSQALTNKLIHGPTSA
LNRVNGADRDSLIELMRGFYQHAPRSNDQSGH
>Mature_432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNAPEAAILSTCNRTELYCATDDRAARDAAIRWLSD
YHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRGT
TEIGAQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLSD
LPARMQEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVSKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRLEVEKAQKMLARGDDPAAVLEALSQALTNKLIHGPTSA
LNRVNGADRDSLIELMRGFYQHAPRSNDQSGH

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=404, Percent_Identity=45.7920792079208, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 47499; Mature: 47499

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNAPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCE
LYCATDDRAARDAAIRWLSDYHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCEECCCHHHHHHHHHHHHCCHHHHHHHH
QILGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLSD
HHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHCCCCCCHHH
LPARMQEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVSKLKDV
HHHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
FLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RRLEVEKAQKMLARGDDPAAVLEALSQALTNKLIHGPTSALNRVNGADRDSLIELMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHH
QHAPRSNDQSGH
HHCCCCCCCCCC
>Mature Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNAPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCE
LYCATDDRAARDAAIRWLSDYHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCEECCCHHHHHHHHHHHHCCHHHHHHHH
QILGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLSD
HHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHCCCCCCHHH
LPARMQEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVSKLKDV
HHHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
FLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RRLEVEKAQKMLARGDDPAAVLEALSQALTNKLIHGPTSALNRVNGADRDSLIELMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHH
QHAPRSNDQSGH
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA