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The map label for this gene is trpC [H]

Identifier: 161526032

GI number: 161526032

Start: 3127648

End: 3128433

Strand: Direct

Name: trpC [H]

Synonym: Bmul_2863

Alternate gene names: 161526032

Gene position: 3127648-3128433 (Clockwise)

Preceding gene: 161526031

Following gene: 161526033

Centisome position: 90.7

GC content: 67.18

Gene sequence:

>786_bases
ATGAGCGACATTCTCGACCGAATCATCGCCGTCAAGCGCGAAGAAGTAGCCGCCGCCATGCGCAGCACGCCGCTCGAGGC
GCTGAAGCTGGAAGCGTCCGCACGCGACCGGCGCGACTTCGTCGGCGCGCTGCGCGCCAAGCATGCGGCCGGCCAGCCGG
CCGTGATCGCCGAAATCAAGAAGGCGAGCCCGTCGAAGGGCGTGCTGCGCGAGCATTTCGTGCCGGCCGACATCGCGCGC
TCGTACGCGGCGCACGGCGCCGCGTGCCTGTCGGTGCTGACCGACGAGCAGTTCTTCCAGGGCAGCGTCCGCTATCTCGA
GGAAGCGCGCGCCGCGTGCGACCTGCCGGTGCTGCGCAAGGACTTCATCGTCGACGCGTACCAGATCCTCGAAGCGCGCG
CGATGGGCGCGGACGCGATCCTGCTGATCGCCGCCGCGCTCGACACGCCGCTGATGCAGGAGCTCGAAGCGTATGCGCAC
TCGCTCGATCTCGCGGTGCTCGTCGAAGTGCACGACCGCAACGAAATGGAGCAGGCGCTGACGCTCAAGACGCCGCTGCT
CGGCATCAACAACCGCAACCTGCGCACGTTCGAAACCTCGATCCGGGCGACGCTCGACATGCTCGACATGATTCCGCAGG
ACCGCATCGTCGTGACCGAATCGGGGATCCTGTCGCGCGCGGACGTCGATACGATGCGCGCGGCGAACGTCAACACGTTC
CTCGTCGGCGAGGCGTTCATGCGTGCCGACCAGCCGGGCGAGGAACTCGCACGGATGTTCTTCTGA

Upstream 100 bases:

>100_bases
GCGATCGCGAGCGGCAAGGCCCGTGCGAAAGTCGACGAACTCGTGCGCTTCACGCAGCAGTTCAAGCGCTGACCCCGTTA
CGAATCAAGCAGGAACCCAC

Downstream 100 bases:

>100_bases
TGGCGATCGAAAAGGAAATCAAGCTCGCACTGCCGGCCGGTCACGCGCCGGCCGCGCACCGCTTCTTCGAGACGCTGACC
GGCGAGCGCGGCCGCGAGAT

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSDILDRIIAVKREEVAAAMRSTPLEALKLEASARDRRDFVGALRAKHAAGQPAVIAEIKKASPSKGVLREHFVPADIAR
SYAAHGAACLSVLTDEQFFQGSVRYLEEARAACDLPVLRKDFIVDAYQILEARAMGADAILLIAAALDTPLMQELEAYAH
SLDLAVLVEVHDRNEMEQALTLKTPLLGINNRNLRTFETSIRATLDMLDMIPQDRIVVTESGILSRADVDTMRAANVNTF
LVGEAFMRADQPGEELARMFF

Sequences:

>Translated_261_residues
MSDILDRIIAVKREEVAAAMRSTPLEALKLEASARDRRDFVGALRAKHAAGQPAVIAEIKKASPSKGVLREHFVPADIAR
SYAAHGAACLSVLTDEQFFQGSVRYLEEARAACDLPVLRKDFIVDAYQILEARAMGADAILLIAAALDTPLMQELEAYAH
SLDLAVLVEVHDRNEMEQALTLKTPLLGINNRNLRTFETSIRATLDMLDMIPQDRIVVTESGILSRADVDTMRAANVNTF
LVGEAFMRADQPGEELARMFF
>Mature_260_residues
SDILDRIIAVKREEVAAAMRSTPLEALKLEASARDRRDFVGALRAKHAAGQPAVIAEIKKASPSKGVLREHFVPADIARS
YAAHGAACLSVLTDEQFFQGSVRYLEEARAACDLPVLRKDFIVDAYQILEARAMGADAILLIAAALDTPLMQELEAYAHS
LDLAVLVEVHDRNEMEQALTLKTPLLGINNRNLRTFETSIRATLDMLDMIPQDRIVVTESGILSRADVDTMRAANVNTFL
VGEAFMRADQPGEELARMFF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=250, Percent_Identity=40.4, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322638, Length=261, Percent_Identity=37.1647509578544, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 28750; Mature: 28619

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILDRIIAVKREEVAAAMRSTPLEALKLEASARDRRDFVGALRAKHAAGQPAVIAEIK
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KASPSKGVLREHFVPADIARSYAAHGAACLSVLTDEQFFQGSVRYLEEARAACDLPVLRK
HCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DFIVDAYQILEARAMGADAILLIAAALDTPLMQELEAYAHSLDLAVLVEVHDRNEMEQAL
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHH
TLKTPLLGINNRNLRTFETSIRATLDMLDMIPQDRIVVTESGILSRADVDTMRAANVNTF
HHHCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHCCCCEE
LVGEAFMRADQPGEELARMFF
EHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
SDILDRIIAVKREEVAAAMRSTPLEALKLEASARDRRDFVGALRAKHAAGQPAVIAEIK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KASPSKGVLREHFVPADIARSYAAHGAACLSVLTDEQFFQGSVRYLEEARAACDLPVLRK
HCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DFIVDAYQILEARAMGADAILLIAAALDTPLMQELEAYAHSLDLAVLVEVHDRNEMEQAL
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHH
TLKTPLLGINNRNLRTFETSIRATLDMLDMIPQDRIVVTESGILSRADVDTMRAANVNTF
HHHCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHCCCCEE
LVGEAFMRADQPGEELARMFF
EHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA