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The map label for this gene is mraW [H]

Identifier: 161526013

GI number: 161526013

Start: 3099930

End: 3100871

Strand: Reverse

Name: mraW [H]

Synonym: Bmul_2844

Alternate gene names: 161526013

Gene position: 3100871-3099930 (Counterclockwise)

Preceding gene: 161526014

Following gene: 161526012

Centisome position: 89.92

GC content: 65.07

Gene sequence:

>942_bases
ATGGGAAACGAATTGCAGCATCGGACGGTGCTGTTGGACGAAGCGGTCGAATCGCTCGTGACGCGTCCGGACGGCATCTA
CGTCGACGGCACGTTCGGGCGCGGCGGTCACAGCCGCGCGGTGCTCGCGCGGCTCGGGCCGGCCGGGCGGCTGATCGCGT
TCGACAAGGATCCGAGGGCGATCGAGACGGCGCAGGGCATCGGCGATGCGCGCTTCTCGATCGTGCATGACAGCTTTGCC
TCGATGCGCGACGCGCTTGCGGCGCGCGGCATCGAGAAGGTGTCGGGTGTGTTGCTGGACCTGGGCGTGTCCTCGCCGCA
GGTGGACGATCCGGCGCGCGGCTTCAGCTTCCGCGCCGATGGTCCGCTGGACATGCGTATGGATCCGACGCGCGGCGAAT
CGGCGGCGGAATGGCTCGCGCGGGCTTCGCTGCAGGAACTGACGGAGGTGATACGAGATTATGGGGAAGAACGGTTTGCT
TTTCAGATTGCAAAGGCGCTTGTTGCTCGCCGGGCAGAGTCCGACCGTCTCGGGCCTCTCGACAGCACGGGCGAGCTTGC
CCAAATCGTGGGTCACGTCGTCAAAACCCGTGAGAAGGGCAAGGATCCGGCAACCCGCACCTTTCAGGCTATACGGATTC
ACGTCAATCAAGAGCTTGCGGACCTGCAAGTCGTACTAGACGCGGCATTGTCGTTGCTGGAGCAAGGGGGGCGGCTGGTG
GTCATCAGCTTTCATTCACTCGAGGACCGGATCGTCAAGCGATTCATGCAGGCGCACGCCAGTGCGCCTGCGGTCGATCG
TCGCCTGCCGATCCGCGCCGTCGACCTCCCGAGCCCGCCGCTCAAGATCATCGGTCGCCAGTTCCCGAGTGAAGCGGAAG
TGGCTGCCAACCCGCGTGCCCGTTCGGCCGTGATGCGCATTGCGGAGCGCCTCACGCCATGA

Upstream 100 bases:

>100_bases
CGCAGACCTACATCGCGAAGGAGCAGGCAGCGATGGCGCAGGGCATGCCCGACGCGCTGAAGAACTTCACGTTCTGATTG
CGGTGACGGAGACGCCCGCG

Downstream 100 bases:

>100_bases
GCCGCTTCAACATCTTCCTGTTGATCATCGTGATGGGCTGTGCGCTGTCCGTCGTCAACTCGACGAACCAGCAGCGGCAG
ATCTTCATCCAGTTGCAGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLGPAGRLIAFDKDPRAIETAQGIGDARFSIVHDSFA
SMRDALAARGIEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASLQELTEVIRDYGEERFA
FQIAKALVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIIGRQFPSEAEVAANPRARSAVMRIAERLTP

Sequences:

>Translated_313_residues
MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLGPAGRLIAFDKDPRAIETAQGIGDARFSIVHDSFA
SMRDALAARGIEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASLQELTEVIRDYGEERFA
FQIAKALVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIIGRQFPSEAEVAANPRARSAVMRIAERLTP
>Mature_312_residues
GNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLGPAGRLIAFDKDPRAIETAQGIGDARFSIVHDSFAS
MRDALAARGIEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASLQELTEVIRDYGEERFAF
QIAKALVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLVV
ISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIIGRQFPSEAEVAANPRARSAVMRIAERLTP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=341, Percent_Identity=36.6568914956012, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI165377202, Length=198, Percent_Identity=37.3737373737374, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786270, Length=314, Percent_Identity=55.0955414012739, Blast_Score=332, Evalue=2e-92,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=37.4622356495468, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=37.4622356495468, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34116; Mature: 33985

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLGPAGRLIAFDKDPRA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEECCCCCH
IETAQGIGDARFSIVHDSFASMRDALAARGIEKVSGVLLDLGVSSPQVDDPARGFSFRAD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GPLDMRMDPTRGESAAEWLARASLQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIIGRQFPSEAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCHHCCCHH
RSAVMRIAERLTP
HHHHHHHHHHCCC
>Mature Secondary Structure 
GNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLGPAGRLIAFDKDPRA
CCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEECCCCCH
IETAQGIGDARFSIVHDSFASMRDALAARGIEKVSGVLLDLGVSSPQVDDPARGFSFRAD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GPLDMRMDPTRGESAAEWLARASLQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIIGRQFPSEAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCHHCCCHH
RSAVMRIAERLTP
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA