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The map label for this gene is murC [H]

Identifier: 161526004

GI number: 161526004

Start: 3088304

End: 3089701

Strand: Reverse

Name: murC [H]

Synonym: Bmul_2835

Alternate gene names: 161526004

Gene position: 3089701-3088304 (Counterclockwise)

Preceding gene: 161526005

Following gene: 161526003

Centisome position: 89.6

GC content: 67.95

Gene sequence:

>1398_bases
ATGAAACACATCGTCAAACACATTCATTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCGGAAGTGCTCGTCAA
TCTCGGCTATCAGGTCAGCGGCTCGGATCTCGCGCGCAACGCGGTGACCGATCGCCTGGCTGCGCTCGGTGCGCGGATCG
CGATCGGCCACGACGCGGCGAACATCGAAGGCGCGAACGCGGTCGTCGTGTCGACGGCCGTGCGCTCGGACAACCCGGAA
GTGCTGGCCGCGCGCGCCCAGCGCGTGCCCATCGTGCAGCGCGCGGTGATGCTCGCGGAACTGATGCGCCTGAAGCAGGG
GATCGCGATCGCCGGCACGCACGGCAAGACCACGACGACGAGCCTCGTCGCGAGCGTGCTCGCGGCCGGCGGCCTCGACC
CGACCTTCGTGATCGGCGGCCGGCTGATCAGCGCCGGCGCGAACGCGCGGCTCGGCACCGGCGACTTCATCGTCGCGGAG
GCCGACGAATCCGACGCGTCGTTCCTGAACCTGTATCCGGTGATCGAAGTGATCACGAATATCGACGCCGATCACATGGA
TACGTACGGCCACGATTTCGCGCGGCTCAAGCAGGCGTTCATCGAATTCACGCAGCGCTTGCCGTTCTACGGCAGCGCGG
TGGTGTGCGTCGACGATCCGAACGTGCGGCAGATCATTCCGTTCATTTCGAAGCCGGTCGTGCGCTACGGCCTGTCGCCC
GACGCGCAGGTGCGCGCGGAGGACATCGACGCGCGCGACGGCCGCATGCATTTCACGGTGATCCGCGAAGGGCGCGCGCC
GCTCGCGGTCGTGCTGAACCTGCCGGGCCTTCACAACGTGCAGAACGCGCTCGCGGCGATCGCGATCGCGACCGATCTCG
GCGTGTCGGACGACGCGATCCAGCAGGCGCTGGCCGAATTCAACGGCGTCGGGCGGCGCTTCCAGCGCTACGGCGACGTG
CCGACCGCCGACGGCGGCCGCTACACGCTGATCGACGACTACGGTCATCACCCGGTCGAGATGGCCGCGACGATCGCGGC
CGCACGCGGTGCGTTTCCCGGCCGGCGGCTCGTACTCGCGTTTCAGCCGCACCGCTATACGCGTACGCGCGACTGCTTCG
ACGATTTCGTCAACGTGCTGTCGACGGTCGATGCGCTGGTGCTGACCGAAGTGTATGCGGCGGGCGAGGCGGCGATCGCG
ACGGCCAACGGCGACGCGCTGTCGCGCGCGCTGCGCGCGGCAGGCAAGGTCGAACCGGTGTTCGTCGAGACGGTCGACGC
GTTGCCGGAGGCACTGGCGAAGGTCGCGCAGGACGGCGACGTAGTAATCACGATGGGCGCGGGTTCGATCGGCGGCGTGC
CGGCGAAGATCGTGCAGAACACGCAACAGAAGGGATGA

Upstream 100 bases:

>100_bases
CGATGGCGGAGCGTTCGCGCTCGCTGGCAAAGCCCGAGGCTACCGACGAAGTCGCGCGCGTGTGCGCGACGGTAGCCGGC
GCGAACCTGGAATCATTGCA

Downstream 100 bases:

>100_bases
CATGAGCGGGATCGATCCGAAACGTTTCGGCAAGGTGGCGGTGTTGTTCGGCGGCGAATCCGCCGAGCGCGAGGTGTCGC
TCACCTCGGGCCGCCTCGTG

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTDRLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPE
VLAARAQRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGDV
PTADGGRYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIA
TANGDALSRALRAAGKVEPVFVETVDALPEALAKVAQDGDVVITMGAGSIGGVPAKIVQNTQQKG

Sequences:

>Translated_465_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTDRLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPE
VLAARAQRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGDV
PTADGGRYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIA
TANGDALSRALRAAGKVEPVFVETVDALPEALAKVAQDGDVVITMGAGSIGGVPAKIVQNTQQKG
>Mature_465_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTDRLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPE
VLAARAQRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGDV
PTADGGRYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIA
TANGDALSRALRAAGKVEPVFVETVDALPEALAKVAQDGDVVITMGAGSIGGVPAKIVQNTQQKG

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=453, Percent_Identity=54.3046357615894, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1790680, Length=473, Percent_Identity=29.8097251585624, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49025; Mature: 49025

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTDRLAALGARIAIGHDAA
CCCHHHHEEEEEECCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHCCEEEECCCCC
NIEGANAVVVSTAVRSDNPEVLAARAQRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHCCCC
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAI
CCCEECCCCCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHH
QQALAEFNGVGRRFQRYGDVPTADGGRYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIATANGDALSRALRAAGKVEPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCHH
FVETVDALPEALAKVAQDGDVVITMGAGSIGGVPAKIVQNTQQKG
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTDRLAALGARIAIGHDAA
CCCHHHHEEEEEECCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHCCEEEECCCCC
NIEGANAVVVSTAVRSDNPEVLAARAQRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHCCCC
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAI
CCCEECCCCCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHH
QQALAEFNGVGRRFQRYGDVPTADGGRYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIATANGDALSRALRAAGKVEPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCHH
FVETVDALPEALAKVAQDGDVVITMGAGSIGGVPAKIVQNTQQKG
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA