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The map label for this gene is exuR [H]

Identifier: 161525910

GI number: 161525910

Start: 2993056

End: 2993778

Strand: Direct

Name: exuR [H]

Synonym: Bmul_2741

Alternate gene names: 161525910

Gene position: 2993056-2993778 (Clockwise)

Preceding gene: 161525906

Following gene: 161525912

Centisome position: 86.79

GC content: 66.8

Gene sequence:

>723_bases
ATGCCGGTCAGACCGGCCATCGTTCACCTCATGAAAAACGTTCCGCATACCGTGACCGACGCCGCCATCGCGACGATCCG
CGACCGGATCGAGGCAGGCGTGTATCCGGTCGGCAGCCTGCTGCCGGCCCAGCGGCAGCTCTCCGAGGAGCTGGAGATCA
GTCGCGCGTCGTTGCGCGAGGCGCTGTCGACGCTCGAAGCGCTCGGCATGCTGCGCATTCGCGCCGGCAAGGGCGTGTAT
GTCGAAAGCGCGCGCGCGACCACCGCGCATGCGTGGCAGTTCGCCGAACAGTCGTCGCCGCCCGACACGTATCAGATGCG
CTACGCGCTCGAAGGCTTCGCCGCGCGGATGGCCGCGCGCGTCGTCAGCGACGACGACATCGCGTGGTTCGAAGACAATC
TCGCCGATCTGCACGTCGCGCTGACGGAGAACGCGCTCGAGGACGCGTCGCAGCTCGACTTCGACTTCCACATGCGCATC
ATCCATCTGGCCGGCAATGCGGCGATCGAATCGGTCCTGCGCAGCAGCGCGGACATCATGAAGGAAAGCCAGCGCATGCC
GTTCTACCGGCGCGAGCTGCTGCTGTCGACCTGGCACGAGCATCGCGCGATCGTCGATGCGCTCAGTGCACGCGACGCGG
CCGCAGCCGGCACCGCGATCGAAACGCACATCTCGAATGCCGCGCAGCGCGCGGGCATCTTTTTCCCGACACCGGGCGCG
TAA

Upstream 100 bases:

>100_bases
AGGGATTTCCCGCCCCGCGGCCGGGTTGGTGCGGCGCGGAAAACCGGCCGTGTCGTGGGTTTCCCGTAGCCGCGGATGCG
CGGGGCGGGCGCGGTTTACA

Downstream 100 bases:

>100_bases
GCGCTGCTACGTCCTCGACGCCGCCGACGGCACGCGATACGCGAGCGCGCACTCGATGAATGCGCGCGCCGCGACGCTGC
GATAGGCGCCCTTGCGCGTG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MPVRPAIVHLMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVY
VESARATTAHAWQFAEQSSPPDTYQMRYALEGFAARMAARVVSDDDIAWFEDNLADLHVALTENALEDASQLDFDFHMRI
IHLAGNAAIESVLRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALSARDAAAAGTAIETHISNAAQRAGIFFPTPGA

Sequences:

>Translated_240_residues
MPVRPAIVHLMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVY
VESARATTAHAWQFAEQSSPPDTYQMRYALEGFAARMAARVVSDDDIAWFEDNLADLHVALTENALEDASQLDFDFHMRI
IHLAGNAAIESVLRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALSARDAAAAGTAIETHISNAAQRAGIFFPTPGA
>Mature_239_residues
PVRPAIVHLMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYV
ESARATTAHAWQFAEQSSPPDTYQMRYALEGFAARMAARVVSDDDIAWFEDNLADLHVALTENALEDASQLDFDFHMRII
HLAGNAAIESVLRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALSARDAAAAGTAIETHISNAAQRAGIFFPTPGA

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=223, Percent_Identity=28.2511210762332, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790780, Length=220, Percent_Identity=29.5454545454545, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790032, Length=228, Percent_Identity=28.5087719298246, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786303, Length=210, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789353, Length=185, Percent_Identity=29.7297297297297, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26389; Mature: 26258

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRPAIVHLMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLRE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHH
ALSTLEALGMLRIRAGKGVYVESARATTAHAWQFAEQSSPPDTYQMRYALEGFAARMAAR
HHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VVSDDDIAWFEDNLADLHVALTENALEDASQLDFDFHMRIIHLAGNAAIESVLRSSADIM
HHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCHHHHHHHHHHHHHHH
KESQRMPFYRRELLLSTWHEHRAIVDALSARDAAAAGTAIETHISNAAQRAGIFFPTPGA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PVRPAIVHLMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLRE
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHH
ALSTLEALGMLRIRAGKGVYVESARATTAHAWQFAEQSSPPDTYQMRYALEGFAARMAAR
HHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VVSDDDIAWFEDNLADLHVALTENALEDASQLDFDFHMRIIHLAGNAAIESVLRSSADIM
HHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCHHHHHHHHHHHHHHH
KESQRMPFYRRELLLSTWHEHRAIVDALSARDAAAAGTAIETHISNAAQRAGIFFPTPGA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA