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The map label for this gene is ubiA [H]

Identifier: 161525826

GI number: 161525826

Start: 2899888

End: 2900751

Strand: Reverse

Name: ubiA [H]

Synonym: Bmul_2657

Alternate gene names: 161525826

Gene position: 2900751-2899888 (Counterclockwise)

Preceding gene: 161525827

Following gene: 161525819

Centisome position: 84.12

GC content: 66.55

Gene sequence:

>864_bases
ATGCTTGCCCGCTTTCCCCTGTACCTGCGCCTTGTCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTGTGGCCGAC
GCTGAACGCGCTGTGGATCGCGTCGGACGGCCATCCGCGCTGGCCGCTGATCGTGATCTTCGCGCTCGGCACGCTGCTGA
TGCGCTCGGCCGGCTGCGCGATGAACGACTACGCGGACCGCGATTTCGACCGGCACGTGAAGCGCACGGCCGACCGGCCG
CTGACGTCGGGCAAGATCCGCGCGTGGGAGGCCGTCGCGATCGCCGTCGGCCTGTCGTTCGTGGCGTTCCTGCTGATCCT
GCCGCTCAATACGCTGACGAAAGAGCTGTCGGTCGTCGCGCTGTTCGTCGCGGGCACCTATCCGTTCATGAAGCGCTTCT
TCGCGATTCCGCAGGCGTATCTCGGGATCGCGTTCGGCTTCGGGATTCCGATGGCGTTCGCGGCCGTGCAGAACACGGTG
CCGCCGCTCGCGTGGGTGATGCTGATCGCGAACGTGTTCTGGTCGATCGCGTACGACACCGAATACGCGATGGTCGACCG
CGACGACGACATCAAGATCGGCATTCGCACGTCGGCGCTGACGTTCGGCCGTTTCGACGTGGCCGCCGTCATGGCGTGCT
ATGCGGTCACGCTCGGGATCTACGTGTGGATCGGCATCGCGCTCGGCTTCGGTGCGGCGTACTGGGTCGGCTGGGCCGCC
GCGGCCGGCTGCGCGGTCTATCACTACACGCTGATCAAGGGCCGCGAACGGATGCCGTGCTTCGCGGCATTCCGCCACAA
CAACTGGCTCGGCGGCGTGCTGTTCGCCGGCATTGCCGCGCATTACCTGATGGCGGGGAGCTGA

Upstream 100 bases:

>100_bases
ACCGATCCGTTCCCCTCGGCCGCGCATCGCGCCGGCCGCACCATGACGCAAACGGCCGTTGGGCTCTAAAATGCCGGGAT
CGTCTTTCCGGTGCTTCGCC

Downstream 100 bases:

>100_bases
GCGGCGGCCCGCGTGGCTTCGTGCCGTGCGCGGCGTGCTGAAGCAGAAAACGAAAAAGCGGCCGAGGCCGCTTTTTTGTT
GCTGCTGCCGGATGATGGCG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLIVIFALGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVGLSFVAFLLILPLNTLTKELSVVALFVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQNTV
PPLAWVMLIANVFWSIAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAVTLGIYVWIGIALGFGAAYWVGWAA
AAGCAVYHYTLIKGRERMPCFAAFRHNNWLGGVLFAGIAAHYLMAGS

Sequences:

>Translated_287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLIVIFALGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVGLSFVAFLLILPLNTLTKELSVVALFVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQNTV
PPLAWVMLIANVFWSIAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAVTLGIYVWIGIALGFGAAYWVGWAA
AAGCAVYHYTLIKGRERMPCFAAFRHNNWLGGVLFAGIAAHYLMAGS
>Mature_287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLIVIFALGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVGLSFVAFLLILPLNTLTKELSVVALFVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQNTV
PPLAWVMLIANVFWSIAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAVTLGIYVWIGIALGFGAAYWVGWAA
AAGCAVYHYTLIKGRERMPCFAAFRHNNWLGGVLFAGIAAHYLMAGS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=274, Percent_Identity=32.8467153284672, Blast_Score=151, Evalue=5e-37,
Organism=Escherichia coli, GI1790473, Length=273, Percent_Identity=52.3809523809524, Blast_Score=271, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17553718, Length=282, Percent_Identity=33.6879432624113, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI32565247, Length=285, Percent_Identity=31.9298245614035, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17553720, Length=338, Percent_Identity=28.698224852071, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=37.956204379562, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=37.593984962406, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324370, Length=201, Percent_Identity=32.3383084577114, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355567, Length=274, Percent_Identity=32.8467153284672, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31676; Mature: 31676

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLIVIFALGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVGLSFVAFLLILPLNTLTKELSVVA
CCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQNTVPPLAWVMLIANVFWSIAYDT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAVTLGIYVWIGIALGFGAAYWVGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGCAVYHYTLIKGRERMPCFAAFRHNNWLGGVLFAGIAAHYLMAGS
HHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLIVIFALGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVGLSFVAFLLILPLNTLTKELSVVA
CCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQNTVPPLAWVMLIANVFWSIAYDT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAVTLGIYVWIGIALGFGAAYWVGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGCAVYHYTLIKGRERMPCFAAFRHNNWLGGVLFAGIAAHYLMAGS
HHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA