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The map label for this gene is hmp [H]

Identifier: 161525818

GI number: 161525818

Start: 2890285

End: 2891493

Strand: Reverse

Name: hmp [H]

Synonym: Bmul_2649

Alternate gene names: 161525818

Gene position: 2891493-2890285 (Counterclockwise)

Preceding gene: 161525819

Following gene: 161525811

Centisome position: 83.85

GC content: 67.49

Gene sequence:

>1209_bases
ATGACCCAGATCACCGCCGATCAGATGGCACGCGTGAAGGCGACCGCTCCCGTCCTCGCCGAACACGGCGCGACGATTAC
GAAGCACTTCTACCAGCGCATGTTCGCGCGCCATCCGGAGTTGAAGAACCTGTTCAACCAGACGCATCAGAAGACGGGCG
CGCAGCCCGAGACGCTCGCGAAGGCCGTCTATGCGTATGCGGCGAACATCGACAATCTGGGCGCGCTCGGCGGTGCGGTG
TCGCGGATTTCGCACAAGCACGCGAGCCTGAACATTCGTCCCGAGCACTATCCGATCGTCGGCGAGAATCTGCTTGCGTC
GATCGTCGAGGTGCTCGGCGACGCGGTCGACGCGGATACGCTCGAAGCGTGGCGCGTCGCCTACGGCCAGCTCGCGCAAA
TCCTGATCGGCGCGGAGGCCGACCTGTACGCGGGTGCCGCCTGGAGCGGATTCCGTCCGTTCAAGGTCGCGCGCAAGGTG
CGCGAAAGCGACGAGATCACGTCGTTCTACCTGGTGCCCGCGGACGGCGGCGCGGCGCCGTCGTTCGAGCCGGGCCAGTA
CGTGACGGTGAAGCGCTTCGTCGGCGATCTCGGCGTCGATCAGCCGCGCCAGTACAGCCTGTCCGACGCGCCGAACGGCA
AGTGGCTGCGCATCTCGGTGAAGCGCGAGTCGGGCGACGCGGAGGCGATTCCGGCCGGCAAGGTGTCGACGCTGATGCAC
GACGGCGTCGAAGCGGGCTCGATCGTCGAGGTGACGGCGCCGATGGGCGATTTCTCGCTGCGGCGCGACGCCGATACGCC
CGTCGTGCTGATCTCGGGCGGCGTCGGCATCACGCCGATGATGTCGATGCTGTCGACGCTCGTCGCCGAAGGCAGCCGGC
GCGACGTGCGGTTCGTCCACGCATGCCGGTCGGGCGCGGTGCACGCGTTCCGCGACTGGCTGAACGACACGGTGCGCGAG
CACGCGAACGTGAAGCGTACGGTGCTGTACGAGCGGGTCGGGCCGAACGACCGCGTCGGCATCGATCACGACCTCGAAGG
GCGTCTGACGCCCGAGCGCCTGAAGCAGTACGCGCTGGAGCCGGACGCCGACTACTACATCTGCGGCCCGATCGCGTTCA
TGAAGGCGCAGCGCGATGCGCTGCTCGCGCTGGGCGTCGCGCCGGAGCGCGTGAATACGGAGATTTTCGGTTCGGGGGCG
CTCGAGTAA

Upstream 100 bases:

>100_bases
GGTAACGCAGCCGGCGCCTTTTTCCGCACTGCGACAATTTGTCCGCCTGGCCTGCGATTTTAAAGAGGTATCGTATCCGC
ATGTTTAACGGAGAACGAAC

Downstream 100 bases:

>100_bases
CGCGTCGCGCAGGCACTCGCGGCTGCGCGTGAAAAAGCCCGGCGTATGCCGGGCTTTGATTTCGTTGCGTGCAGGACGTC
AGGCGCGCAGCACGAGCGTG

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTQITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGAQPETLAKAVYAYAANIDNLGALGGAV
SRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRVAYGQLAQILIGAEADLYAGAAWSGFRPFKVARKV
RESDEITSFYLVPADGGAAPSFEPGQYVTVKRFVGDLGVDQPRQYSLSDAPNGKWLRISVKRESGDAEAIPAGKVSTLMH
DGVEAGSIVEVTAPMGDFSLRRDADTPVVLISGGVGITPMMSMLSTLVAEGSRRDVRFVHACRSGAVHAFRDWLNDTVRE
HANVKRTVLYERVGPNDRVGIDHDLEGRLTPERLKQYALEPDADYYICGPIAFMKAQRDALLALGVAPERVNTEIFGSGA
LE

Sequences:

>Translated_402_residues
MTQITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGAQPETLAKAVYAYAANIDNLGALGGAV
SRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRVAYGQLAQILIGAEADLYAGAAWSGFRPFKVARKV
RESDEITSFYLVPADGGAAPSFEPGQYVTVKRFVGDLGVDQPRQYSLSDAPNGKWLRISVKRESGDAEAIPAGKVSTLMH
DGVEAGSIVEVTAPMGDFSLRRDADTPVVLISGGVGITPMMSMLSTLVAEGSRRDVRFVHACRSGAVHAFRDWLNDTVRE
HANVKRTVLYERVGPNDRVGIDHDLEGRLTPERLKQYALEPDADYYICGPIAFMKAQRDALLALGVAPERVNTEIFGSGA
LE
>Mature_401_residues
TQITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGAQPETLAKAVYAYAANIDNLGALGGAVS
RISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRVAYGQLAQILIGAEADLYAGAAWSGFRPFKVARKVR
ESDEITSFYLVPADGGAAPSFEPGQYVTVKRFVGDLGVDQPRQYSLSDAPNGKWLRISVKRESGDAEAIPAGKVSTLMHD
GVEAGSIVEVTAPMGDFSLRRDADTPVVLISGGVGITPMMSMLSTLVAEGSRRDVRFVHACRSGAVHAFRDWLNDTVREH
ANVKRTVLYERVGPNDRVGIDHDLEGRLTPERLKQYALEPDADYYICGPIAFMKAQRDALLALGVAPERVNTEIFGSGAL
E

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=399, Percent_Identity=41.1027568922306, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1787658, Length=264, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788104, Length=254, Percent_Identity=27.1653543307087, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321673, Length=396, Percent_Identity=37.1212121212121, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43735; Mature: 43604

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGAQPETLA
CCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADT
HHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHH
LEAWRVAYGQLAQILIGAEADLYAGAAWSGFRPFKVARKVRESDEITSFYLVPADGGAAP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCC
SFEPGQYVTVKRFVGDLGVDQPRQYSLSDAPNGKWLRISVKRESGDAEAIPAGKVSTLMH
CCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHH
DGVEAGSIVEVTAPMGDFSLRRDADTPVVLISGGVGITPMMSMLSTLVAEGSRRDVRFVH
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHH
ACRSGAVHAFRDWLNDTVREHANVKRTVLYERVGPNDRVGIDHDLEGRLTPERLKQYALE
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCC
PDADYYICGPIAFMKAQRDALLALGVAPERVNTEIFGSGALE
CCCCEEEECHHHHHHHHCCCEEEECCCCHHCCCEECCCCCCC
>Mature Secondary Structure 
TQITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGAQPETLA
CCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADT
HHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHH
LEAWRVAYGQLAQILIGAEADLYAGAAWSGFRPFKVARKVRESDEITSFYLVPADGGAAP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCC
SFEPGQYVTVKRFVGDLGVDQPRQYSLSDAPNGKWLRISVKRESGDAEAIPAGKVSTLMH
CCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHH
DGVEAGSIVEVTAPMGDFSLRRDADTPVVLISGGVGITPMMSMLSTLVAEGSRRDVRFVH
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHH
ACRSGAVHAFRDWLNDTVREHANVKRTVLYERVGPNDRVGIDHDLEGRLTPERLKQYALE
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCC
PDADYYICGPIAFMKAQRDALLALGVAPERVNTEIFGSGALE
CCCCEEEECHHHHHHHHCCCEEEECCCCHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]