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The map label for this gene is dgk [H]

Identifier: 161525798

GI number: 161525798

Start: 2864228

End: 2864914

Strand: Direct

Name: dgk [H]

Synonym: Bmul_2629

Alternate gene names: 161525798

Gene position: 2864228-2864914 (Clockwise)

Preceding gene: 161525797

Following gene: 161525799

Centisome position: 83.06

GC content: 66.23

Gene sequence:

>687_bases
ATGAACCCGACACCGCTGACCGTCACCGCGCCCGATCTGCGCGCCCCGCATCGCTATCTCGTGATCGAAGGGCCGATCGG
CGTCGGCAAGACGACGCTCGCACGGCTGCTGGCCGAACGCTGGTCGATGCAGACGCTGCTCGAGCGGCCGCAGGACAATC
CGTTTCTCGAACGCTTCTATCGCGACACCGCGCGCTATGCGCTGCCGACGCAGCTGTCGTTCGCGCTGCAGCGCGCGCAG
CAGTCAGCCGAGCTGATCGGCGCACTCGATACGGGGCGGCCCGTTGTCGCCGATTTCATGCCGCAGAAGAACGACATCTT
CGCGCGGCTGAACCTGCCCGAGGACGAATGGCAGCTGTACCGGTCGATCGCCGCGCATCTCGAAGCGCCGCGCGCGCCGG
CGCCCGATCTCGTCGTCTATCTGCAGGCGAGCCCCGAAGTGCTGTTCGCGCGGATCCAGAAGCGCGGGCTGCCGATGGAG
CTGCAGATCAGCGATGCGTACCTGCGCGCGCTCGTCGACGCCTACAACGAATTCTTCTATCACTACGACCGCACGCCCGT
GCTGACGGTCGCCGCGGAACACCTGAACCCGCTGGATTCCCCCGAAGACTTCGCGCTGCTGGTCGAGCGCATCGAAACGA
TGCGCGGCCGCAAGGAATTCTTCGTCAAGGGCGAGACGACGCGCTGA

Upstream 100 bases:

>100_bases
TCGCTGCGGTCGCGCACCAGCGCATCGAGAAGGTGCAGACCTGTCAGTGCCTGATGAAGGCGCTCGCCGCCGGCGACGGC
GCCGACAAGAACCGCTGCCG

Downstream 100 bases:

>100_bases
CGCGCGCCTCGCCCGTCGTTTTTCACTCATCGAACCGGATTTCCCCATGACCTATCTCCAGGAATCGAGCCGGCCTGCCG
TGACGGTGCCGAAGCTGCAG

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNPTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLAERWSMQTLLERPQDNPFLERFYRDTARYALPTQLSFALQRAQ
QSAELIGALDTGRPVVADFMPQKNDIFARLNLPEDEWQLYRSIAAHLEAPRAPAPDLVVYLQASPEVLFARIQKRGLPME
LQISDAYLRALVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPEDFALLVERIETMRGRKEFFVKGETTR

Sequences:

>Translated_228_residues
MNPTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLAERWSMQTLLERPQDNPFLERFYRDTARYALPTQLSFALQRAQ
QSAELIGALDTGRPVVADFMPQKNDIFARLNLPEDEWQLYRSIAAHLEAPRAPAPDLVVYLQASPEVLFARIQKRGLPME
LQISDAYLRALVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPEDFALLVERIETMRGRKEFFVKGETTR
>Mature_228_residues
MNPTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLAERWSMQTLLERPQDNPFLERFYRDTARYALPTQLSFALQRAQ
QSAELIGALDTGRPVVADFMPQKNDIFARLNLPEDEWQLYRSIAAHLEAPRAPAPDLVVYLQASPEVLFARIQKRGLPME
LQISDAYLRALVDAYNEFFYHYDRTPVLTVAAEHLNPLDSPEDFALLVERIETMRGRKEFFVKGETTR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 26081; Mature: 26081

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLAERWSMQTLLERPQDNPFLERFY
CCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RDTARYALPTQLSFALQRAQQSAELIGALDTGRPVVADFMPQKNDIFARLNLPEDEWQLY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
RSIAAHLEAPRAPAPDLVVYLQASPEVLFARIQKRGLPMELQISDAYLRALVDAYNEFFY
HHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHH
HYDRTPVLTVAAEHLNPLDSPEDFALLVERIETMRGRKEFFVKGETTR
HCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCC
>Mature Secondary Structure
MNPTPLTVTAPDLRAPHRYLVIEGPIGVGKTTLARLLAERWSMQTLLERPQDNPFLERFY
CCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RDTARYALPTQLSFALQRAQQSAELIGALDTGRPVVADFMPQKNDIFARLNLPEDEWQLY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
RSIAAHLEAPRAPAPDLVVYLQASPEVLFARIQKRGLPMELQISDAYLRALVDAYNEFFY
HHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHH
HYDRTPVLTVAAEHLNPLDSPEDFALLVERIETMRGRKEFFVKGETTR
HCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]