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The map label for this gene is kbl [C]

Identifier: 161525770

GI number: 161525770

Start: 2829934

End: 2831286

Strand: Direct

Name: kbl [C]

Synonym: Bmul_2601

Alternate gene names: 161525770

Gene position: 2829934-2831286 (Clockwise)

Preceding gene: 161525769

Following gene: 161525771

Centisome position: 82.06

GC content: 63.93

Gene sequence:

>1353_bases
ATGAGCAAGACCAAAACCCCCGGCCTGCCGGGCCTGACCTCGGCCCTGAAGAACAAGCTCATCCAGCAGGCACTCGAGCG
CAAGCTGCGCGAAGCCGGGCGTGACCAGCCCACGGCTTCGCCCGTCGCCGGCCGAAAAACGGCCTCGTCGGTGCCCGAGG
CGTACACGCGCTTCGACCAGTATCCGGGCTACCGCCAGCTGCGCATCATGAACGACGGCGCCGCCCGGCTCGGCGTGCGC
AGCCCGTTCTTTAAGCTGCACGAAGGCACCGCCGGCGCGCAGACCGAAATCGCAGGCAATACGTATATCAATTACGCGAG
CTACAACTACCTCGACATGTCGGGCGACCCGGTTGTCTCGCAGGCGGCCAAGGACGCGATCGACCGATACGGCACATCGG
TATCTGCCAGCCGCCTGGTCTCGGGCGAACGCCCGATTCACCGCGAACTAGAGCGCACCCTCGCCGATCTGTACGGCGTG
GACGACGCGATCACATTCGTGAGCGGCCATGCGGCCAACGTGACCACGATCGGTTATCTGTTCGGGCCGCGCGATCTGGT
GATCCACGACGAGCTAATCCACAACAGCGTGCTCCAGGGGATCCAGCTTTCCGGCGCGAAGCGCTTTTCGTTCGCGCACA
ACGACGCTGATGCGCTTGAACGGTTACTGACCGAGCAGCGGCACCAGTTCGAACGCGTGCTGATCGTGTTGGAAGGCATC
TACAGCATGGACGGCGACTACCCCGACCTGCCGCGTTTCGTCGACATTAAGCGCCGCCATCGGGCATTTCTGATGGTGGA
CGAAGCGCATTCGATGGGCGTGATGGGCAAGACGGGGCGCGGGATTCGCGAGCACTTTGGCCTCGCCGGCGATGCCGTCG
ATATCTGGATGGGTACGCTGAGCAAATCGCTGGCCGGCTGCGGCGGTTATATCGCCGGCGAGACGGCGCTCGTCGAGCAT
CTGAAGTTTCTCGCGCCGGGGTTCCTGTACAGCGTGGGCATGCCGCCGCCGGTGGCCGCGGCGTCCCTCGCGGCGCTGCG
GCGCATGCTGGAGTTGCCAGAGCGCGTGGCGACGCTGCAGGCGCGCGGACAGTATTTTCTTGCCCAGGCCAAGGCCGCGG
GGATCGATACGGGCAGCAGTGCGGGGATAGCGGTCATTCCGGCGATTCTGGGCAGTTCGCTGCGGGCCACCAAGTGGTCG
GAGGCGCTGTTCCAGCAGGGTATCAATGTGCAGCCGATTCTGTATCCGGCCGTGCCGGAACAGTCGGCGCGGTTGCGGTT
CTTCATCTCCTGCGCCCACAGTGAAACGGAGATTGATAAAGTCATTGCTTGCATGCGACGATTGAAGGATTAG

Upstream 100 bases:

>100_bases
GAGGACGTTTCCAGCGAAGCGCTCGCCGAGTTCACCGACGAAATCAAGGCCGCACAAGAAGCGGGCCACAAGCCGCAACG
CATGATCCGATAAGCGCGAC

Downstream 100 bases:

>100_bases
AGCCCAGCCGCCAATCACTATACGAAATGGCAGATCGACAAACATACTCAAGAGCGTGGTCATTTTCCACGTTCCAACCT
CATATCACAATAAGACACCG

Product: glycine C-acetyltransferase

Products: NA

Alternate protein names: AONS/AKB ligase; 7-keto-8-amino-pelargonic acid synthase; 7-KAP synthase; KAPA synthase; 8-amino-7-ketopelargonate synthase; Alpha-oxoamine synthase; L-alanine--pimeloyl-CoA ligase [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSKTKTPGLPGLTSALKNKLIQQALERKLREAGRDQPTASPVAGRKTASSVPEAYTRFDQYPGYRQLRIMNDGAARLGVR
SPFFKLHEGTAGAQTEIAGNTYINYASYNYLDMSGDPVVSQAAKDAIDRYGTSVSASRLVSGERPIHRELERTLADLYGV
DDAITFVSGHAANVTTIGYLFGPRDLVIHDELIHNSVLQGIQLSGAKRFSFAHNDADALERLLTEQRHQFERVLIVLEGI
YSMDGDYPDLPRFVDIKRRHRAFLMVDEAHSMGVMGKTGRGIREHFGLAGDAVDIWMGTLSKSLAGCGGYIAGETALVEH
LKFLAPGFLYSVGMPPPVAAASLAALRRMLELPERVATLQARGQYFLAQAKAAGIDTGSSAGIAVIPAILGSSLRATKWS
EALFQQGINVQPILYPAVPEQSARLRFFISCAHSETEIDKVIACMRRLKD

Sequences:

>Translated_450_residues
MSKTKTPGLPGLTSALKNKLIQQALERKLREAGRDQPTASPVAGRKTASSVPEAYTRFDQYPGYRQLRIMNDGAARLGVR
SPFFKLHEGTAGAQTEIAGNTYINYASYNYLDMSGDPVVSQAAKDAIDRYGTSVSASRLVSGERPIHRELERTLADLYGV
DDAITFVSGHAANVTTIGYLFGPRDLVIHDELIHNSVLQGIQLSGAKRFSFAHNDADALERLLTEQRHQFERVLIVLEGI
YSMDGDYPDLPRFVDIKRRHRAFLMVDEAHSMGVMGKTGRGIREHFGLAGDAVDIWMGTLSKSLAGCGGYIAGETALVEH
LKFLAPGFLYSVGMPPPVAAASLAALRRMLELPERVATLQARGQYFLAQAKAAGIDTGSSAGIAVIPAILGSSLRATKWS
EALFQQGINVQPILYPAVPEQSARLRFFISCAHSETEIDKVIACMRRLKD
>Mature_449_residues
SKTKTPGLPGLTSALKNKLIQQALERKLREAGRDQPTASPVAGRKTASSVPEAYTRFDQYPGYRQLRIMNDGAARLGVRS
PFFKLHEGTAGAQTEIAGNTYINYASYNYLDMSGDPVVSQAAKDAIDRYGTSVSASRLVSGERPIHRELERTLADLYGVD
DAITFVSGHAANVTTIGYLFGPRDLVIHDELIHNSVLQGIQLSGAKRFSFAHNDADALERLLTEQRHQFERVLIVLEGIY
SMDGDYPDLPRFVDIKRRHRAFLMVDEAHSMGVMGKTGRGIREHFGLAGDAVDIWMGTLSKSLAGCGGYIAGETALVEHL
KFLAPGFLYSVGMPPPVAAASLAALRRMLELPERVATLQARGQYFLAQAKAAGIDTGSSAGIAVIPAILGSSLRATKWSE
ALFQQGINVQPILYPAVPEQSARLRFFISCAHSETEIDKVIACMRRLKD

Specific function: Catalyzes the decarboxylative condensation of pimeloyl- CoA and L-alanine to produce 8-amino-7-oxononanoate (AON), coenzyme A and/or converts 2-amino-3-ketobutyrate to glycine and acetyl-CoA [H]

COG id: COG0156

COG function: function code H; 7-keto-8-aminopelargonate synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI119220554, Length=363, Percent_Identity=33.8842975206612, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI4758668, Length=355, Percent_Identity=32.9577464788732, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI7657118, Length=342, Percent_Identity=35.3801169590643, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI284448556, Length=342, Percent_Identity=35.3801169590643, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI83977444, Length=356, Percent_Identity=32.0224719101124, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI83977442, Length=356, Percent_Identity=32.3033707865169, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI83977440, Length=356, Percent_Identity=32.0224719101124, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI5454084, Length=288, Percent_Identity=30.9027777777778, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4502025, Length=329, Percent_Identity=31.306990881459, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI40316939, Length=329, Percent_Identity=31.306990881459, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1790046, Length=364, Percent_Identity=35.7142857142857, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1786993, Length=347, Percent_Identity=32.8530259365994, Blast_Score=156, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI32566772, Length=373, Percent_Identity=32.4396782841823, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17560912, Length=378, Percent_Identity=33.0687830687831, Blast_Score=211, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17560914, Length=378, Percent_Identity=33.0687830687831, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71994529, Length=359, Percent_Identity=32.8690807799443, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71982617, Length=281, Percent_Identity=32.7402135231317, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71982625, Length=284, Percent_Identity=32.3943661971831, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6320267, Length=355, Percent_Identity=32.112676056338, Blast_Score=200, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6320438, Length=362, Percent_Identity=30.3867403314917, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323954, Length=267, Percent_Identity=29.2134831460674, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24662918, Length=341, Percent_Identity=33.7243401759531, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI17136286, Length=366, Percent_Identity=30.8743169398907, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17137420, Length=349, Percent_Identity=30.0859598853868, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24653280, Length=286, Percent_Identity=28.6713286713287, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24653276, Length=286, Percent_Identity=28.6713286713287, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24653278, Length=286, Percent_Identity=28.6713286713287, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR004723
- InterPro:   IPR010962
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.3.1.29; =2.3.1.47 [H]

Molecular weight: Translated: 49081; Mature: 48950

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTKTPGLPGLTSALKNKLIQQALERKLREAGRDQPTASPVAGRKTASSVPEAYTRFDQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
YPGYRQLRIMNDGAARLGVRSPFFKLHEGTAGAQTEIAGNTYINYASYNYLDMSGDPVVS
CCCCEEEEEECCCCHHCCCCCCCHHHCCCCCCCCEEECCCCEEEECEEEEEECCCCHHHH
QAAKDAIDRYGTSVSASRLVSGERPIHRELERTLADLYGVDDAITFVSGHAANVTTIGYL
HHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEE
FGPRDLVIHDELIHNSVLQGIQLSGAKRFSFAHNDADALERLLTEQRHQFERVLIVLEGI
ECCCEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YSMDGDYPDLPRFVDIKRRHRAFLMVDEAHSMGVMGKTGRGIREHFGLAGDAVDIWMGTL
HHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
SKSLAGCGGYIAGETALVEHLKFLAPGFLYSVGMPPPVAAASLAALRRMLELPERVATLQ
HHHHHCCCCCCCCHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARGQYFLAQAKAAGIDTGSSAGIAVIPAILGSSLRATKWSEALFQQGINVQPILYPAVPE
HCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCC
QSARLRFFISCAHSETEIDKVIACMRRLKD
CCCCEEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKTKTPGLPGLTSALKNKLIQQALERKLREAGRDQPTASPVAGRKTASSVPEAYTRFDQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
YPGYRQLRIMNDGAARLGVRSPFFKLHEGTAGAQTEIAGNTYINYASYNYLDMSGDPVVS
CCCCEEEEEECCCCHHCCCCCCCHHHCCCCCCCCEEECCCCEEEECEEEEEECCCCHHHH
QAAKDAIDRYGTSVSASRLVSGERPIHRELERTLADLYGVDDAITFVSGHAANVTTIGYL
HHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEE
FGPRDLVIHDELIHNSVLQGIQLSGAKRFSFAHNDADALERLLTEQRHQFERVLIVLEGI
ECCCEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YSMDGDYPDLPRFVDIKRRHRAFLMVDEAHSMGVMGKTGRGIREHFGLAGDAVDIWMGTL
HHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
SKSLAGCGGYIAGETALVEHLKFLAPGFLYSVGMPPPVAAASLAALRRMLELPERVATLQ
HHHHHCCCCCCCCHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARGQYFLAQAKAAGIDTGSSAGIAVIPAILGSSLRATKWSEALFQQGINVQPILYPAVPE
HCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCC
QSARLRFFISCAHSETEIDKVIACMRRLKD
CCCCEEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA