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The map label for this gene is xdhA [H]

Identifier: 161525720

GI number: 161525720

Start: 2774110

End: 2776464

Strand: Reverse

Name: xdhA [H]

Synonym: Bmul_2551

Alternate gene names: 161525720

Gene position: 2776464-2774110 (Counterclockwise)

Preceding gene: 161525721

Following gene: 161525719

Centisome position: 80.51

GC content: 68.41

Gene sequence:

>2355_bases
ATGAACCAGCAAGCAGAACCGTTCCTCAGCACCCTCGATCCGCAAGCCGACGCCGCGCAGGTGCACGTGTCGCGTGCGCA
CGAGTCCGCGCATCTGCACGTGAGCGGGCGCGCGACCTACACCGACGACATTCCGCTCGTCGCGGGCACGCTGCACGCGG
CGCTCGGGTTGTCCGCGAAGCCGCACGCAAGGATCGTATCGATGAATTTCGACGCGGTGCGCGCGACGCCGGGCGTGGTC
GCGGTGTTCACCGCCGACGACATTCCGGGCGTCAACGACTGCGGCCCGATCGTCCACGACGATCCGGTGCTCGCGCAGGG
CGTCGTGCAGTACGTCGGCCAGCCGATGTTCATCGTCGTCGCGACGTCGCACGATGTCGCGCGGCTCGCCGCGCGGCGCG
CGCAGGTCGAATACGAGGAGCTGCCGGCGATCCTGACCGCGCAGGAAGCGCGCAAGGCCGAGTCGTACGTGATTCCGCCG
CTGAAGCTCGCGCGCGGCGACGCGGCGGCACGGATCGCCGCTGCGCCGCATCGCGAGTCGGGCGAGATGCTGCTCGGCGG
CCAGGAGCAGTTTTATCTGGAAGGGCAGATCGCATACGCGGTGCCGAAGGACGACGACGGCATGCACGTGTACTGCTCGA
CGCAGCACCCGAGCGAGATGCAGCATCTGGTCGCGCACGTGCTCGGCGTCGCGTCGCACAACGTGCTCGTCGAGTGCCGC
CGGATGGGCGGCGGGTTCGGCGGCAAGGAATCGCAGTCGGGGCTGTTCGCGTGCTGCGCGGCGCTCGCCGCCTGGAAGCT
GCTGTGTCCGGTGAAGCTGCGTCCGGACCGCGACGACGACATGATGATCACCGGCAAGCGGCACGACTTCCATTACCGCT
TCGACGTCGGCTACGACGACGACGGCCGCATCGACGGCGTGTCGCTCGACATGACCTCGCGCTGCGGTTTCTCGGCCGAT
TTGTCGGGCCCCGTGATGACACGCGCGGTCTGCCACTTCGACAACGCATACTGGCTGTCCGACGTCGCGATCGCCGGCTA
CTGCGGCAAGACCAACACGCAGTCGAACACTGCGTTTCGCGGTTTCGGCGGCCCGCAGGGCGCGTTCGCGATCGAGTACA
TCCTCGACGACATCGCGCGCACGCTCGGCCGCGATCCGCTCGACGTCCGCTACGCGAACCTGTACGGCAAGACCGAGCGC
AACGTCACGCCGTACGGCCAGACCGTCGAGGACAACGTGCTGCACGAACTGCTCGCCGAACTCGAGGCGACGAGCGACTA
TCGCGCGCGGCGCGACGGCGTGCGCGCGTTCAACGCCCGCAACGCGGTGCTGAAGAAGGGCATCGCGCTGACGCCGGTGA
AGTTCGGGATCGCGTTCAACGTCACGCACTTCAACCAGGCCGGCGCGCTCGTGCATATCTATACGGACGGCTCGGTGCTC
GTGAACCACGGCGGCACGGAGATGGGGCAGGGGCTGAACACGAAGGTCGCGCAGGTCGTCGCGCACGAGCTCGGGATCCG
TTTCGGCCGCATCCGCGTGACCGCGACCGATACGAGCAAGGTCGCCAATACGTCGGCGACCGCCGCGTCGACCGGTTCGG
ATCTGAACGGCAAGGCCGCGCAGGACGCCGCGCGCCAGCTGCGCGAGCGGCTCGCCGTGTTCGCGGCGAAGCAGTACGGC
GAGGGCCGGGTCGAGGCGGCCGACGTGAAGTTCGCCAACGACTGCGTGTGGATCGGCACGACGGCCGTGCCGTTCGGCGA
CGTGATCGCGAAGGCGTATCTCGCGCGCGTGCAGCTCTGGTCCGACGGCTTCTATGCGACGCCGAAGCTGCACTGGGACC
AGTCGAAGCTGCAGGGGCGGCCGTTCTACTACTACTCGTACGGCGCGGCCGTGTCGGAAGTCGTGATCGACACGCTGACG
GGCGAGATGCGCACGCTGCGCGTCGACGCGCTGCACGACGTCGGCGCATCGCTGAACCCGGCGCTCGACATCGGTCAGGT
CGAAGGCGCGTTCATCCAGGGGATGGGCTGGCTGACGACCGAGGAGCTGTGGTGGAACGCGGGCGGCAAGCTGATGACGC
ACGCGCCCTCGACGTACAAGATTCCGACCGTCAACGACACGCCGCCCGAATTCAACGTGCGGCTGTTCAAGAACCGCAAC
GTCGAGGACAGCATTCACCGCTCGAAGGCCGTCGGCGAGCCGCCGCTGCTGCTGCCGTTCTCGGTGTTCTTCGCCGTGCG
CGACGCGATCGCGGCGGTCGGCGACTATCGCGTGAATCCGCCGCTCGACGCACCGGCGACCGGCGAGTCGATCCTGCGTG
CGGTGCAGGCCGTGCGCGCGGCGCGGGCAGCCTGA

Upstream 100 bases:

>100_bases
GCTGGAGACGCGTCCGCACGATCCGCTGCCGCCGCAAGCCCTGAACGTGCGCGAAGTGCCCGCCGAAGCGGCGCGTGTCT
GACGACGGAGAACACCGAAC

Downstream 100 bases:

>100_bases
CATGCGTGCGCCGGCCCGTTCGCTGCATTCGCCTGCACGCGCGGTCTCGCCCGACGCGGCCGCGTTTCCGCGCGGCACCG
GCACCCGCAATCGCGCGACA

Product: xanthine dehydrogenase, molybdopterin binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHARIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIVHDDPVLAQGVVQYVGQPMFIVVATSHDVARLAARRAQVEYEELPAILTAQEARKAESYVIPP
LKLARGDAAARIAAAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDDDGRIDGVSLDMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLSDVAIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARTLGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLHELLAELEATSDYRARRDGVRAFNARNAVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQYG
EGRVEAADVKFANDCVWIGTTAVPFGDVIAKAYLARVQLWSDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFKNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYRVNPPLDAPATGESILRAVQAVRAARAA

Sequences:

>Translated_784_residues
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHARIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIVHDDPVLAQGVVQYVGQPMFIVVATSHDVARLAARRAQVEYEELPAILTAQEARKAESYVIPP
LKLARGDAAARIAAAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDDDGRIDGVSLDMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLSDVAIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARTLGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLHELLAELEATSDYRARRDGVRAFNARNAVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQYG
EGRVEAADVKFANDCVWIGTTAVPFGDVIAKAYLARVQLWSDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFKNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYRVNPPLDAPATGESILRAVQAVRAARAA
>Mature_784_residues
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHARIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIVHDDPVLAQGVVQYVGQPMFIVVATSHDVARLAARRAQVEYEELPAILTAQEARKAESYVIPP
LKLARGDAAARIAAAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDDDGRIDGVSLDMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLSDVAIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARTLGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLHELLAELEATSDYRARRDGVRAFNARNAVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQYG
EGRVEAADVKFANDCVWIGTTAVPFGDVIAKAYLARVQLWSDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFKNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYRVNPPLDAPATGESILRAVQAVRAARAA

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=771, Percent_Identity=42.8015564202335, Blast_Score=584, Evalue=1e-166,
Organism=Homo sapiens, GI71773480, Length=755, Percent_Identity=38.0132450331126, Blast_Score=478, Evalue=1e-134,
Organism=Escherichia coli, GI1789230, Length=752, Percent_Identity=27.6595744680851, Blast_Score=206, Evalue=7e-54,
Organism=Escherichia coli, GI1789246, Length=736, Percent_Identity=26.6304347826087, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1786478, Length=727, Percent_Identity=24.3466299862448, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=764, Percent_Identity=40.5759162303665, Blast_Score=507, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI32566215, Length=708, Percent_Identity=32.0621468926554, Blast_Score=336, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17539860, Length=722, Percent_Identity=31.994459833795, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI17737937, Length=764, Percent_Identity=43.1937172774869, Blast_Score=579, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24647199, Length=762, Percent_Identity=31.3648293963255, Blast_Score=328, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24647193, Length=779, Percent_Identity=32.0924261874198, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24647201, Length=762, Percent_Identity=31.6272965879265, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24647195, Length=775, Percent_Identity=30.5806451612903, Blast_Score=295, Evalue=6e-80,
Organism=Drosophila melanogaster, GI24647197, Length=775, Percent_Identity=30.5806451612903, Blast_Score=295, Evalue=9e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 84805; Mature: 84805

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAK
CCCCCCCHHHHCCCCCCHHHEEHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHCCCCC
PHARIVSMNFDAVRATPGVVAVFTADDIPGVNDCGPIVHDDPVLAQGVVQYVGQPMFIVV
CCEEEEEECCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEE
ATSHDVARLAARRAQVEYEELPAILTAQEARKAESYVIPPLKLARGDAAARIAAAPHRES
ECCCHHHHHHHHHHCCCHHHCCHHEEHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCCC
GEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
CCEEECCCCEEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHH
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCEEEEEECCCCC
DGRIDGVSLDMTSRCGFSADLSGPVMTRAVCHFDNAYWLSDVAIAGYCGKTNTQSNTAFR
CCCEEEEEEEHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCEEEEEECCCCCCCCCCEEE
GFGGPQGAFAIEYILDDIARTLGRDPLDVRYANLYGKTERNVTPYGQTVEDNVLHELLAE
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LEATSDYRARRDGVRAFNARNAVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
HHCCCHHHHHHHCHHHHHHHHHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEEE
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAA
EECCCHHHCCCCCHHHHHHHHHHHCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHHH
QDAARQLRERLAVFAAKQYGEGRVEAADVKFANDCVWIGTTAVPFGDVIAKAYLARVQLW
HHHHHHHHHHHHHHHHHHCCCCCEEEECEEECCCEEEECCCCCCHHHHHHHHHHHHHEEE
SDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRTLRVDALHDVGASLNP
CCCEEECCEEECCHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
ALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFKNRN
CCCCCCCCCHHCCCCCCCCHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCEEEEEECCC
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYRVNPPLDAPATGESILRAVQAVRA
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
ARAA
HHCC
>Mature Secondary Structure
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAK
CCCCCCCHHHHCCCCCCHHHEEHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHCCCCC
PHARIVSMNFDAVRATPGVVAVFTADDIPGVNDCGPIVHDDPVLAQGVVQYVGQPMFIVV
CCEEEEEECCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEE
ATSHDVARLAARRAQVEYEELPAILTAQEARKAESYVIPPLKLARGDAAARIAAAPHRES
ECCCHHHHHHHHHHCCCHHHCCHHEEHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCCC
GEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
CCEEECCCCEEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHH
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCEEEEEECCCCC
DGRIDGVSLDMTSRCGFSADLSGPVMTRAVCHFDNAYWLSDVAIAGYCGKTNTQSNTAFR
CCCEEEEEEEHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCEEEEEECCCCCCCCCCEEE
GFGGPQGAFAIEYILDDIARTLGRDPLDVRYANLYGKTERNVTPYGQTVEDNVLHELLAE
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LEATSDYRARRDGVRAFNARNAVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
HHCCCHHHHHHHCHHHHHHHHHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEEE
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAA
EECCCHHHCCCCCHHHHHHHHHHHCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHHH
QDAARQLRERLAVFAAKQYGEGRVEAADVKFANDCVWIGTTAVPFGDVIAKAYLARVQLW
HHHHHHHHHHHHHHHHHHCCCCCEEEECEEECCCEEEECCCCCCHHHHHHHHHHHHHEEE
SDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRTLRVDALHDVGASLNP
CCCEEECCEEECCHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
ALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFKNRN
CCCCCCCCCHHCCCCCCCCHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCEEEEEECCC
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYRVNPPLDAPATGESILRAVQAVRA
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
ARAA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]