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The map label for this gene is galE [H]

Identifier: 161525675

GI number: 161525675

Start: 2723571

End: 2724536

Strand: Reverse

Name: galE [H]

Synonym: Bmul_2506

Alternate gene names: 161525675

Gene position: 2724536-2723571 (Counterclockwise)

Preceding gene: 161525676

Following gene: 161525674

Centisome position: 79.01

GC content: 66.87

Gene sequence:

>966_bases
GTGACTCATATCGTCGTAACGGGCGCAAACGGTTTCGTCGGCCGCGCGGTGTGCCGCCGCGCGCTGGCGGCGGGACACAC
CGTGACCGCGCTTGTGCGACGACCAGGAGAATGCGTCGGAGGCGTGCGTGAATGGGTGCACGCCGAGGTCGATTTCGATG
GGCTCAATGCCGCGTGGCCGACTGATCTCGGCCCCGACTGCGTGATCCATCTCGCCGCACGTGTGCATGTGATGCGCGAC
GAGTCCCCCGATCCTGACGTCGCGTTCGACGTGACCAACGTCGCAGGCACCCTGCGTCTCGCCGAGGCCGCCCGCAAACA
TGGCGTGCGCCGAATCGTGTTCGCGAGCAGCATCAAAGCGGTAGGTGAGGGTGACGGCGGAATGCCGCTGTCGGAACGGG
CATCACCGGACCCACGGGATGCCTACGGGCGCTCCAAGCTGCGCGCGGAGCGGGAGCTTGCGTGGTTCGGTACAGCCAAC
GGGCTCGATGTCGTGATTGTGCGCCCGCCACTCGTCTACGGTCCGGGCGTTCGCGCCAACTTCCTGCGCATGATGGATAC
GGTCGCGCGCGGGATGCCGCTACCGCTCGGTTCCATTGCGGCACGCCGCAGCATCGTCTATGTCGACAACCTCGCCGACG
CACTGCTGCATTGCGCGGTGGATCCGCGTGCCGCAGGCGAATGTTTCCACGTTGCCGACGACGATGCGCCGTCGGTCACT
GATCTGTTACGACTGCTCGGCGACGCACTCGGGAAGCCAGCCCGCCTGATTCGGGTTCCGTCCGCTGTGCTGCGGGCGCT
CGGTACGCTGACCGGCCGCCGAGCGGCAATCGACCGCCTCACCGGTAGCCTTCAGCTCGATACGGGCCGGATCAAGCGCG
TCCTCGGCTGGCACCCGCCTTACACGACGCGCCAGGGCCTCGAAGCCACCGCCGCATGGTATCGTTCGCGCGATACACGA
CAATAG

Upstream 100 bases:

>100_bases
TCCACCACGGCGGCGGCGCGTCTCGCAAGGGCTTTGCGCACATACGCATGTTCGCCGCGTCGGCGTTTAAGTTCTACAAC
CGCTTCGGCTGGAGGTTTTC

Downstream 100 bases:

>100_bases
CCGACATGCATCTCCCGATACCCGCCTGGCTTGCCGCGACCGCGGTGGCCCTGGTTGCTGCCGTCGCGTCGACGGCGATC
TTGCGCGTTCTGCTCGCGAC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTHIVVTGANGFVGRAVCRRALAAGHTVTALVRRPGECVGGVREWVHAEVDFDGLNAAWPTDLGPDCVIHLAARVHVMRD
ESPDPDVAFDVTNVAGTLRLAEAARKHGVRRIVFASSIKAVGEGDGGMPLSERASPDPRDAYGRSKLRAERELAWFGTAN
GLDVVIVRPPLVYGPGVRANFLRMMDTVARGMPLPLGSIAARRSIVYVDNLADALLHCAVDPRAAGECFHVADDDAPSVT
DLLRLLGDALGKPARLIRVPSAVLRALGTLTGRRAAIDRLTGSLQLDTGRIKRVLGWHPPYTTRQGLEATAAWYRSRDTR
Q

Sequences:

>Translated_321_residues
MTHIVVTGANGFVGRAVCRRALAAGHTVTALVRRPGECVGGVREWVHAEVDFDGLNAAWPTDLGPDCVIHLAARVHVMRD
ESPDPDVAFDVTNVAGTLRLAEAARKHGVRRIVFASSIKAVGEGDGGMPLSERASPDPRDAYGRSKLRAERELAWFGTAN
GLDVVIVRPPLVYGPGVRANFLRMMDTVARGMPLPLGSIAARRSIVYVDNLADALLHCAVDPRAAGECFHVADDDAPSVT
DLLRLLGDALGKPARLIRVPSAVLRALGTLTGRRAAIDRLTGSLQLDTGRIKRVLGWHPPYTTRQGLEATAAWYRSRDTR
Q
>Mature_320_residues
THIVVTGANGFVGRAVCRRALAAGHTVTALVRRPGECVGGVREWVHAEVDFDGLNAAWPTDLGPDCVIHLAARVHVMRDE
SPDPDVAFDVTNVAGTLRLAEAARKHGVRRIVFASSIKAVGEGDGGMPLSERASPDPRDAYGRSKLRAERELAWFGTANG
LDVVIVRPPLVYGPGVRANFLRMMDTVARGMPLPLGSIAARRSIVYVDNLADALLHCAVDPRAAGECFHVADDDAPSVTD
LLRLLGDALGKPARLIRVPSAVLRALGTLTGRRAAIDRLTGSLQLDTGRIKRVLGWHPPYTTRQGLEATAAWYRSRDTRQ

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994969, Length=343, Percent_Identity=27.1137026239067, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081792, Length=338, Percent_Identity=26.0355029585799, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34563; Mature: 34432

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIVVTGANGFVGRAVCRRALAAGHTVTALVRRPGECVGGVREWVHAEVDFDGLNAAWP
CCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC
TDLGPDCVIHLAARVHVMRDESPDPDVAFDVTNVAGTLRLAEAARKHGVRRIVFASSIKA
CCCCHHHHHHHHHHHHEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
VGEGDGGMPLSERASPDPRDAYGRSKLRAERELAWFGTANGLDVVIVRPPLVYGPGVRAN
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCEEECCCCHHH
FLRMMDTVARGMPLPLGSIAARRSIVYVDNLADALLHCAVDPRAAGECFHVADDDAPSVT
HHHHHHHHHCCCCCCHHHHHHHCEEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHH
DLLRLLGDALGKPARLIRVPSAVLRALGTLTGRRAAIDRLTGSLQLDTGRIKRVLGWHPP
HHHHHHHHHHCCCHHEEECCHHHHHHHHHHCCHHHHHHHHCCCEEECHHHHHHHHCCCCC
YTTRQGLEATAAWYRSRDTRQ
CCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
THIVVTGANGFVGRAVCRRALAAGHTVTALVRRPGECVGGVREWVHAEVDFDGLNAAWP
CEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC
TDLGPDCVIHLAARVHVMRDESPDPDVAFDVTNVAGTLRLAEAARKHGVRRIVFASSIKA
CCCCHHHHHHHHHHHHEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
VGEGDGGMPLSERASPDPRDAYGRSKLRAERELAWFGTANGLDVVIVRPPLVYGPGVRAN
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCEEECCCCHHH
FLRMMDTVARGMPLPLGSIAARRSIVYVDNLADALLHCAVDPRAAGECFHVADDDAPSVT
HHHHHHHHHCCCCCCHHHHHHHCEEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHH
DLLRLLGDALGKPARLIRVPSAVLRALGTLTGRRAAIDRLTGSLQLDTGRIKRVLGWHPP
HHHHHHHHHHCCCHHEEECCHHHHHHHHHHCCHHHHHHHHCCCEEECHHHHHHHHCCCCC
YTTRQGLEATAAWYRSRDTRQ
CCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]