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The map label for this gene is glmS [H]

Identifier: 161525672

GI number: 161525672

Start: 2718656

End: 2720473

Strand: Direct

Name: glmS [H]

Synonym: Bmul_2503

Alternate gene names: 161525672

Gene position: 2718656-2720473 (Clockwise)

Preceding gene: 161525671

Following gene: 161525677

Centisome position: 78.84

GC content: 67.16

Gene sequence:

>1818_bases
ATGTGCGGCATTGTCGGCGCAGTTGCGCAGCGTAATATCGTTCCGGTGCTGATCGAAGGATTGCGGCGCCTCGAATACCG
TGGCTACGATTCGTGCGGCGTCGCCGTGCTCGAAGCGGATGCGCCCAAGCGCGCGCGCAGCGTCGCGCGCGTCGCCGATC
TCGACGCGCAGGTGCGCGACTCGCACCTCGAAGGCACGACCGGCATCGCGCATACGCGCTGGGCGACGCACGGCGCGCCC
GTCACGCACAACGCGCATCCGATCTTCTCGTCCGGCGCGCTCGCGCTCGTGCACAACGGCATCATCGAAAACTTCGAGCC
GCTGCGCGACGCACTGCGCGCGAAGGGCTACGAGTTCGTGTCGCAAACCGACACCGAAGTGATCGCGCACCTCGTGCATA
GCCTCTACCGCGGCGATCTGTTCGACGCCGTGCGCGAAGCGGTGCAGCAGCTGCATGGCGCTTATGCGATCGCGGTGATC
CACAAGGATCAGCCGCATACGGTCGTCGGCGCGCGTCAGGGCTCGCCGCTCGTGGTCGGCCACGGCGACGGCGAGAACTT
CGTCGCGTCGGACGCGCTCGCGCTCGCCGGCAGCACCGACCGCTTCACGTTCCTCGAGGAAGGCGACGTCTGCGAGCTAT
CGCTCGACGGCGTGAAGATCGTCGATCGCCACGGCGCGCTCGCGCAGCGCGAGATCCGCGTGGTCAGCGCCTACGGCGGC
GCGGTCGAACTCGGCCCGTATCGCCACTTTATGCAGAAGGAAATCTTCGAGCAGCCGCGCGCGATCGGCGACACGGTGCC
GCAGACGGACGCATTCGACGCGACGCTGTTCGGCGACGCCGCGCCCGCCGCGTTCGCGCAGATCGACAGCCTGCTGATCC
TCGCGTGCGGCACGAGCTACTACTCGGGGCTGACGGCGAAATACTGGCTCGAGTCGATCGCGAAGATCCCGACGCAGGTC
GAGATCGCGAGCGAATACCGTTATCGCGACTCGGTGCCGAACCCGCGTCAGCTCGTGCTGGTGATCTCGCAGTCGGGTGA
AACGGCCGACACGCTCGCCGCGCTCAAGCACGCGCAGGCGCTCGGCCACACGCACACGCTCGCGATCTGCAACGTCGCGA
CGAGCGCGATGGTGCGCCTGACCGGCATGCAGTTCCTCACGCACGCGGGCACCGAGATCGGCGTCGCGTCGACGAAGGCG
TTCACGACGCAGCTCGTCGCGCTGTTCGTGCTTGCCGCGACGCTCGGCAAGCTGCGCGGGCACGTCGACGCCGCGCAGGA
AACGGAATATCTGAAGCAGCTGCGCCATCTGCCGGCTGCGCTGAACAGCGTGCTCGCGCTCGAGCCGCAGATCATCGCGT
GGGCCGACGAATTCGCACGCAAGGAAAACGCGCTGTTCCTCGGCCGCGGGCTGCACTACCCGATCGCGCTCGAAGGCGCG
CTGAAGCTGAAGGAAATCTCGTACATCCACGCGGAGGCGTACCCGGCCGGCGAGCTGAAGCACGGCCCGCTCGCGCTCGT
CACCGAAGCGATGCCGGTGATTACCGTTGCGCCGAACGACACGCTGCTCGAGAAGCTGAAGTCGAACATGCAGGAAGTGC
GCGCGCGCGGCGGCGAGCTCTACGTGTTCGCCGATGCGGACACGCAGATCGTCAACGGCGACGGCCTGCACGTGATCCGG
ATGCCCGAGCACTACGGGCAGTTGTCCCCGGTTCTGCACGTGGTGCCGCTGCAGCTGCTCGCGTATCACACCGCGTGCGC
GCGCGGCACCGATGTTGACAAGCCGCGCAATCTGGCGAAATCGGTGACGGTCGAATAA

Upstream 100 bases:

>100_bases
AAGTACGGGCCGAAACGAGCGGCTATAAGTTAGCTGGGTAAAAACTCAACATCATGCGAGTGCCGTACGGCGCCCGCTTC
CCATAGAAGGTAGATTTTTC

Downstream 100 bases:

>100_bases
TTCTGATGAGTACCGGGACGGTTGCGTCGCACCGTCCCGGTAGGTATAGAGTCGCGCAGTTGGAAATTCGCGGATGGCAT
GACATCTCTCGACATGCCTC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEADAPKRARSVARVADLDAQVRDSHLEGTTGIAHTRWATHGAP
VTHNAHPIFSSGALALVHNGIIENFEPLRDALRAKGYEFVSQTDTEVIAHLVHSLYRGDLFDAVREAVQQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFVASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFAQIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRDSVPNPRQLVLVISQSGETADTLAALKHAQALGHTHTLAICNVATSAMVRLTGMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQETEYLKQLRHLPAALNSVLALEPQIIAWADEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNGDGLHVIR
MPEHYGQLSPVLHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEADAPKRARSVARVADLDAQVRDSHLEGTTGIAHTRWATHGAP
VTHNAHPIFSSGALALVHNGIIENFEPLRDALRAKGYEFVSQTDTEVIAHLVHSLYRGDLFDAVREAVQQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFVASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFAQIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRDSVPNPRQLVLVISQSGETADTLAALKHAQALGHTHTLAICNVATSAMVRLTGMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQETEYLKQLRHLPAALNSVLALEPQIIAWADEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNGDGLHVIR
MPEHYGQLSPVLHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEADAPKRARSVARVADLDAQVRDSHLEGTTGIAHTRWATHGAP
VTHNAHPIFSSGALALVHNGIIENFEPLRDALRAKGYEFVSQTDTEVIAHLVHSLYRGDLFDAVREAVQQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFVASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFAQIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRDSVPNPRQLVLVISQSGETADTLAALKHAQALGHTHTLAICNVATSAMVRLTGMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQETEYLKQLRHLPAALNSVLALEPQIIAWADEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNGDGLHVIR
MPEHYGQLSPVLHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=36.6959064327485, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=35.9124087591241, Blast_Score=375, Evalue=1e-104,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=55.1554828150573, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=229, Percent_Identity=29.2576419213974, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=431, Percent_Identity=38.2830626450116, Blast_Score=275, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI17532899, Length=441, Percent_Identity=37.18820861678, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17532897, Length=441, Percent_Identity=37.18820861678, Blast_Score=269, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=37.4164810690423, Blast_Score=262, Evalue=9e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=29.1666666666667, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=35.7843137254902, Blast_Score=113, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=36.2043795620438, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI28573187, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24659598, Length=257, Percent_Identity=28.0155642023346, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24659604, Length=233, Percent_Identity=27.0386266094421, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65347; Mature: 65347

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEADAPKRARSVARVADLDAQVRD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHH
SHLEGTTGIAHTRWATHGAPVTHNAHPIFSSGALALVHNGIIENFEPLRDALRAKGYEFV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGDLFDAVREAVQQLHGAYAIAVIHKDQPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFVASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
CCCCCCCCCCCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCHHHHHEEEEEECCC
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFAQIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHEEEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRDSVPNPRQLVLVISQSGETADTLAALKHAQA
HCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAICNVATSAMVRLTGMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQETEYLKQLRHLPAALNSVLALEPQIIAWADEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNGDGLHVIRMPEHYGQLSPVLHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEADAPKRARSVARVADLDAQVRD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHH
SHLEGTTGIAHTRWATHGAPVTHNAHPIFSSGALALVHNGIIENFEPLRDALRAKGYEFV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGDLFDAVREAVQQLHGAYAIAVIHKDQPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFVASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
CCCCCCCCCCCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCHHHHHEEEEEECCC
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFAQIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHEEEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRDSVPNPRQLVLVISQSGETADTLAALKHAQA
HCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAICNVATSAMVRLTGMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQETEYLKQLRHLPAALNSVLALEPQIIAWADEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNGDGLHVIRMPEHYGQLSPVLHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]