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The map label for this gene is ribB [H]

Identifier: 161525610

GI number: 161525610

Start: 2655634

End: 2656776

Strand: Direct

Name: ribB [H]

Synonym: Bmul_2440

Alternate gene names: 161525610

Gene position: 2655634-2656776 (Clockwise)

Preceding gene: 161525609

Following gene: 161525611

Centisome position: 77.01

GC content: 67.98

Gene sequence:

>1143_bases
ATGACGCTCGCCTCCACGCCCGACATCATCGCCGAGCTGAAAGCCGGCCGGATGGTGATCCTCGTCGACGAAGAAGACCG
CGAAAACGAAGGCGACCTCGTGATTGCCGCCGAATTCGTCACGCCGGAAGCGATCAACTTCATGGCCAAGTACGGCCGCG
GCCTCATTTGTCTGACGTTGACGCAGGAACGCTGCAAGCAGCTGCAACTGCCGCTGATGACGTACCGCAACGGCACGCAG
TACGGCACCGCATTCACGGTCAGCATCGAAGCCGCCGAAGGCGTGACGACCGGGATCTCGGCAGCCGACCGCGCGCATAC
GATCGCGACCGCGGTCGCGCACGACGCGCGTCCCGAGCAGATCGTGCAGCCGGGCCACGTGTTCCCGATCATGGCGCAGC
CGGGCGGCGTGCTCGTGCGCGCCGGGCACACCGAGGCGGGCTGCGACCTGACCGCGCTCGCGGGCCTCACGCCGGCCGCG
GTGATCTGCGAGGTCATCAAGGACGACGGGACGATGGCGCGCCTGCCCGACCTGATCGAGTTCGCGCAGCAGCACGGTCT
GAAGATCGGCACGATCGCCGACCTGATCCATTACCGCAGCCGCACCGAATCGATCATCGAGCGCGTCGCCGAGCGCACGA
TGCAGACCGCGCACGGCGCGTTCCGCGCGGTGCTCTACCGCGACCAGCCGACCGGCTCGCCGCACATCGCACTCGTGCGC
GGCCAGCCGTCGCCGGACGCCGACACGCCGGTGCGCGTGCACGAGCCGCTGTCGGTGCTCGATCTGCTCGAAACGGGCGT
GTCGACCCACTCGTGGACGCTCGACGCCGCGATGCGCGAGATCGCGCAGCGCGACCTCGGCGTCGTCGTGCTGCTCAACT
GCGGCGATACGAAGGAACATCTCGTCGACGTCTTCAAGGCGTTCGACGAGGAAGAGAAGGCGGCCGCGCTGAAGCGCCGG
CCGGTCGATTTCAAGACGTTCGGCATCGGCGCGCAGATTCTGCGCGATGTCGGCGTCGGCAAGATGCAGGTGCTGTCGAA
TCCGCGCAAGCTGGGCAGCATGTCCGGCTACGGTCTCGAAGTGACGGGTTTCGTTCCGATGCCCGGCGGCGAGGCCAAGC
CCTGCCCGGCGCCGCACGCGTGA

Upstream 100 bases:

>100_bases
GCACCGCGTTCCGGCCCGTTCGCGGGCCGTGCGCGGGCGCGCCGGCCGAAACGCGGCGCGGCTAGCGTAAAATACGCACT
TTCCTCTTTCTCGCCCCCTT

Downstream 100 bases:

>100_bases
CCCGCCACGGCGCTTTCGCCCAATAACCGTTCATCCAACCACGGACAGATCATGGAAATCGGACAATACCAACCGAATCT
CGAAGGCGACGGCCTGCGTA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMAKYGRGLICLTLTQERCKQLQLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRAHTIATAVAHDARPEQIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEVIKDDGTMARLPDLIEFAQQHGLKIGTIADLIHYRSRTESIIERVAERTMQTAHGAFRAVLYRDQPTGSPHIALVR
GQPSPDADTPVRVHEPLSVLDLLETGVSTHSWTLDAAMREIAQRDLGVVVLLNCGDTKEHLVDVFKAFDEEEKAAALKRR
PVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLEVTGFVPMPGGEAKPCPAPHA

Sequences:

>Translated_380_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMAKYGRGLICLTLTQERCKQLQLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRAHTIATAVAHDARPEQIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEVIKDDGTMARLPDLIEFAQQHGLKIGTIADLIHYRSRTESIIERVAERTMQTAHGAFRAVLYRDQPTGSPHIALVR
GQPSPDADTPVRVHEPLSVLDLLETGVSTHSWTLDAAMREIAQRDLGVVVLLNCGDTKEHLVDVFKAFDEEEKAAALKRR
PVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLEVTGFVPMPGGEAKPCPAPHA
>Mature_379_residues
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMAKYGRGLICLTLTQERCKQLQLPLMTYRNGTQY
GTAFTVSIEAAEGVTTGISAADRAHTIATAVAHDARPEQIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAV
ICEVIKDDGTMARLPDLIEFAQQHGLKIGTIADLIHYRSRTESIIERVAERTMQTAHGAFRAVLYRDQPTGSPHIALVRG
QPSPDADTPVRVHEPLSVLDLLETGVSTHSWTLDAAMREIAQRDLGVVVLLNCGDTKEHLVDVFKAFDEEEKAAALKRRP
VDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLEVTGFVPMPGGEAKPCPAPHA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=196, Percent_Identity=53.5714285714286, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=41.0891089108911, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40884; Mature: 40753

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMAKYGRGLICLTL
CCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKQLQLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRAHTIATAVAHDARPEQ
CHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEVIKDDGTMARLPDLIE
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FAQQHGLKIGTIADLIHYRSRTESIIERVAERTMQTAHGAFRAVLYRDQPTGSPHIALVR
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEE
GQPSPDADTPVRVHEPLSVLDLLETGVSTHSWTLDAAMREIAQRDLGVVVLLNCGDTKEH
CCCCCCCCCCEEECCCHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEEEEECCCCHHH
LVDVFKAFDEEEKAAALKRRPVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLE
HHHHHHHHCCHHHHHHHHCCCCCEEEECCHHHHHHHCCCCHHHHHCCCHHHCCCCCCCEE
VTGFVPMPGGEAKPCPAPHA
EEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMAKYGRGLICLTL
CCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKQLQLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRAHTIATAVAHDARPEQ
CHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEVIKDDGTMARLPDLIE
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FAQQHGLKIGTIADLIHYRSRTESIIERVAERTMQTAHGAFRAVLYRDQPTGSPHIALVR
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEE
GQPSPDADTPVRVHEPLSVLDLLETGVSTHSWTLDAAMREIAQRDLGVVVLLNCGDTKEH
CCCCCCCCCCEEECCCHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEEEEECCCCHHH
LVDVFKAFDEEEKAAALKRRPVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLE
HHHHHHHHCCHHHHHHHHCCCCCEEEECCHHHHHHHCCCCHHHHHCCCHHHCCCCCCCEE
VTGFVPMPGGEAKPCPAPHA
EEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]