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The map label for this gene is ribE [H]

Identifier: 161525608

GI number: 161525608

Start: 2654029

End: 2654658

Strand: Direct

Name: ribE [H]

Synonym: Bmul_2438

Alternate gene names: 161525608

Gene position: 2654029-2654658 (Clockwise)

Preceding gene: 161525607

Following gene: 161525609

Centisome position: 76.96

GC content: 67.3

Gene sequence:

>630_bases
ATGTTTACCGGAATTGTCGCGGCAGTCGGCCGCATCGAATCGATCAATCCGCTCGGCGCGTCGCCGGACGCCGGCGTGCG
GCTGACCGTGAATGCCGGCGGCCTCGACCTCGCGGACGTCGCGCTCGGCGACAGCATCGCGATCCAGGGCGCCTGCATGA
CGGTGATCGCCAAGACCGACACGACCTTCGACGTCGACGTGTCGCGCGAAAGCCTGAACCGCACGGTCGGGCTCGCGCAG
CCGGGCGACGTGAATCTCGAGAAGGCGCTGCGCGCGCACGACCGGCTCGGCGGCCATATCGTGTCGGGCCACGTCGACGG
GCTCGGCACCGTGTCGCGCTTCGCGCCGGTCGGCGAATCGCACGAGCTGCGGATCGTCGCGCCGCGCGAACTCGGCCGCT
ATCTCGCGTACAAGGGTTCGATCACGGTGAACGGCGTGAGCCTGACCGTCAACGCGGTCGAGGATCGCCCGGACGGCTCC
GAGTTCTCGATCAACCTGATTCCCCATACGGTCGAGGTGACGACGCTGCGCCACCTGAAGGCCGGCGACCGGGTCAATCT
CGAAGTCGACATGATTGCGCGCTATGTGGAGCGGATGTTGACGATGTCGCAGGGCGTGAGCCAGGACTGA

Upstream 100 bases:

>100_bases
CGCGGCTCGTGTTCCACCATATCGAGCGGATCGGCGACGATCTGCGGATCCTGGCGCGTATCGCGCCGCCCCCCGCCACT
CATTGAACGGAATCGTCACG

Downstream 100 bases:

>100_bases
CGACGGCGCGACGCGATGCGCCCGCCGCCCGTGGGTGGCGGCCGTCGCGAGCCGCATCCGGAACTCGCGGCCGCTGCGTG
TGGCCTACCGGCTCCCGGCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MFTGIVAAVGRIESINPLGASPDAGVRLTVNAGGLDLADVALGDSIAIQGACMTVIAKTDTTFDVDVSRESLNRTVGLAQ
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFAPVGESHELRIVAPRELGRYLAYKGSITVNGVSLTVNAVEDRPDGS
EFSINLIPHTVEVTTLRHLKAGDRVNLEVDMIARYVERMLTMSQGVSQD

Sequences:

>Translated_209_residues
MFTGIVAAVGRIESINPLGASPDAGVRLTVNAGGLDLADVALGDSIAIQGACMTVIAKTDTTFDVDVSRESLNRTVGLAQ
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFAPVGESHELRIVAPRELGRYLAYKGSITVNGVSLTVNAVEDRPDGS
EFSINLIPHTVEVTTLRHLKAGDRVNLEVDMIARYVERMLTMSQGVSQD
>Mature_209_residues
MFTGIVAAVGRIESINPLGASPDAGVRLTVNAGGLDLADVALGDSIAIQGACMTVIAKTDTTFDVDVSRESLNRTVGLAQ
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFAPVGESHELRIVAPRELGRYLAYKGSITVNGVSLTVNAVEDRPDGS
EFSINLIPHTVEVTTLRHLKAGDRVNLEVDMIARYVERMLTMSQGVSQD

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=212, Percent_Identity=33.4905660377358, Blast_Score=93, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319733, Length=218, Percent_Identity=35.7798165137615, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22125; Mature: 22125

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVAAVGRIESINPLGASPDAGVRLTVNAGGLDLADVALGDSIAIQGACMTVIAKTD
CCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHCCCCEEECCEEEEEEEECC
TTFDVDVSRESLNRTVGLAQPGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFAPVGES
CEEEEECCHHHHHHEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHCCCCCC
HELRIVAPRELGRYLAYKGSITVNGVSLTVNAVEDRPDGSEFSINLIPHTVEVTTLRHLK
CCEEEECHHHHCCCEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCEEEEEEEEECC
AGDRVNLEVDMIARYVERMLTMSQGVSQD
CCCEEEEEHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFTGIVAAVGRIESINPLGASPDAGVRLTVNAGGLDLADVALGDSIAIQGACMTVIAKTD
CCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHCCCCEEECCEEEEEEEECC
TTFDVDVSRESLNRTVGLAQPGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFAPVGES
CEEEEECCHHHHHHEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHCCCCCC
HELRIVAPRELGRYLAYKGSITVNGVSLTVNAVEDRPDGSEFSINLIPHTVEVTTLRHLK
CCEEEECHHHHCCCEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCEEEEEEEEECC
AGDRVNLEVDMIARYVERMLTMSQGVSQD
CCCEEEEEHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]