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The map label for this gene is ftsK2 [H]

Identifier: 161525593

GI number: 161525593

Start: 2635175

End: 2637514

Strand: Reverse

Name: ftsK2 [H]

Synonym: Bmul_2423

Alternate gene names: 161525593

Gene position: 2637514-2635175 (Counterclockwise)

Preceding gene: 161525597

Following gene: 161525592

Centisome position: 76.48

GC content: 66.97

Gene sequence:

>2340_bases
ATGCGCGGCCCGTTCTCTTTATACGGATTCATGGCAAAAGCTCCTTATTCCGCCCAGGCACAGGCGTTGCCGCACCGGAT
GTCGAAGCTCCTCATGGAGATCCGCTGGATTCTCCAGGTCGCGCTCTGCGCATTTCTCGTGATGGCGCTGCTCAGCTATA
GCCGGCGCGATCCCAGCTGGACGCACGCCGCGCAGGTCGACCACATCTCGAACTGGGCCGGCCGCGTCGGCGCGTGGACG
GCCGACATCGTGCTGCTGCTGTTCGGCCTGTCCGCGTACTGGCTGATCGTGCCGCTCGCGCGGCGCATCGCGGTCAACTA
TCGGCGCATCACGCGCCACGACGCGCTTGCCGACGAGCCCGAGCGGCCGATCGGCTGGCTCACCGAGATCTTCGCGTTCG
TGCTCGTGGTGCTCGCATGCGACGGCATCGAGGCGCTGCGCATGTGGTCGCTGAAAGTGCAGCTGCCGCGCGCGCCGGGC
GGCGTCGTCGGCGAGGCCGTCGCGGGCGCGATGTCGCATGCGTTCGGCTTCACGGGCGGCACGCTGCTGCTGCTGATCGC
GCTCGCGATCGGCCTGTCGCTGTATTTCCGCTTTTCGTGGCTGGCCGTCGCCGAGCGCGTCGGCGGTGCGATCCTGTCCG
CAGTCAACGTCGCGAAGCTGCGCCGCGAGGCCGAGCGCGACCGCAAGCTCGGCGAAGCCGCGGCGGTGCGCCGCGAGGGC
AAGGTCGAGGAAGAGCGCGTGCGCATCGAGGATCACGAGCCGGTGACGATCGTGCCGCCGGTCGTCACGCCGGCCAAGTC
CGAGCGCGTCGAGCGCGAGCGTCAGGTGCCGCTGTTTACCGACCTGCCCGGCGATTCGACGCTGCCGCCCGTGTCGCTGC
TCGATCCCGCGCCGAAGACGCAGGAATCGATCTCCGCCGATACGCTCGAATTCACGTCGCGGCTGATCGAGAAGAAGCTG
AAGGACTTCGGCGTAGAGGCGAGCGTCGTCGCCGCGTATCCGGGCCCGGTCGTCACGCGCTACGAGATCGAACCGGCCAC
CGGCGTGAAGGGCAGCCAGATCGTGAACCTCGCGAAGGATCTCGCGCGTTCGCTGTCGCTCGTGTCGATCCGCGTCGTCG
AGACGATTCCGGGCAAGAACTACATGGCGCTCGAACTGCCGAACCAGCGCCGCCAGACGGTGTACCTGTCCGAGATCATC
GGCTCCGAGGTCTATGCGGCCGCGCCGTCCGCGCTGACGCTGAGCCTCGGCAAGGACATCAGCGGCAAGCCGGTGTGCGC
CGATCTCGCGAAGATGCCGCACCTGCTGGTCGCCGGCACGACGGGTTCGGGCAAGTCGGTCGGCATCAACGCGATGATCC
TGTCGCTGCTGTACAAGGCCACCGCCGAGCAGGTGCGGCTGATCCTGATCGATCCGAAGATGCTCGAAATGAGCGTCTAC
GAAGGCATTCCGCATCTGCTGTGTCCGGTCGTCACGGACATGCGTCAGGCGGGCCATGCGCTGAACTGGACCGTCGCCGA
GATGGAGCGCCGCTACAAGCTGATGAGCAAGCTCGGCGTGCGCAATCTCGCGGGCTACAACAACAAGATCGACGAGGCGG
CCAAGCGCGAGGAAAAGATTCCGAATCCGTTCAGCCTGACGCCCGAGGATCCGGAGCCGCTCGGCCGGCTGCCGAACATC
GTCGTCGTGATCGACGAGCTCGCCGATCTGATGATGGTCGTCGGCAAGAAGGTCGAGGAGTTGATCGCGCGGATCGCGCA
GAAGGCGCGCGCGGCCGGCATCCATCTGATCCTCGCGACGCAGCGTCCGTCGGTCGACGTGATCACCGGCCTGATCAAGG
CGAACGTGCCGACGCGGATCGCGTTCCAGGTGTCGTCGAAGATCGACTCGCGCACGATTCTCGACCAGATGGGCGCCGAG
TCGCTGCTCGGGATGGGCGACATGCTGTACCTGCCGCCGGGCACCGGGCTGCCGGTGCGCGTGCACGGCGCGTTCGTCGC
CGACGACGAAGTGCATCGCGTCGTCGAGAAGCTCAAGGAGCAGGGCGAGCCGAATTACGTCGAGGGCCTGCTCGAAGGCG
GCACCGCCGACGGCGACGAGGGCTCGGCGGGCGCGGGAACCGGCGAAGCGGGCGCGGAGTCTGATCCGCTGTACGACCAG
GCGGTCGAGATCGTGATCAAGAACCGCCGCGCATCGATCTCGCTCGTGCAGCGTCATCTGCGGATCGGCTACAACCGCGC
GGCACGGCTGCTCGAACAGATGGAGCAGTCGGGGCTCGTGTCGGCGATGTCGTCGAGCGGCAACCGCGAAATTCTTGTGC
CGGTACGCGACGCGGAATGA

Upstream 100 bases:

>100_bases
GCTTCGGCATCCGGCCCGCCGATGTAACCGTCATTTACACTTGGGCGCCCGATGCAGCGTTTACAATAAGCGGGATCGAA
CGACAGGCGGGACGCGCGGC

Downstream 100 bases:

>100_bases
AGTCTGCGGCGCCCGCGGCGCCGGCCACCCACGGAGAAAACCGCATCATGCAGCAACTTTCGTTCGTCCCTTCCCTTCGT
TCGACGCGCCGCTGGCTCGG

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MRGPFSLYGFMAKAPYSAQAQALPHRMSKLLMEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHISNWAGRVGAWT
ADIVLLLFGLSAYWLIVPLARRIAVNYRRITRHDALADEPERPIGWLTEIFAFVLVVLACDGIEALRMWSLKVQLPRAPG
GVVGEAVAGAMSHAFGFTGGTLLLLIALAIGLSLYFRFSWLAVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREG
KVEEERVRIEDHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPPVSLLDPAPKTQESISADTLEFTSRLIEKKL
KDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNYMALELPNQRRQTVYLSEII
GSEVYAAAPSALTLSLGKDISGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVY
EGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKIPNPFSLTPEDPEPLGRLPNI
VVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAE
SLLGMGDMLYLPPGTGLPVRVHGAFVADDEVHRVVEKLKEQGEPNYVEGLLEGGTADGDEGSAGAGTGEAGAESDPLYDQ
AVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPVRDAE

Sequences:

>Translated_779_residues
MRGPFSLYGFMAKAPYSAQAQALPHRMSKLLMEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHISNWAGRVGAWT
ADIVLLLFGLSAYWLIVPLARRIAVNYRRITRHDALADEPERPIGWLTEIFAFVLVVLACDGIEALRMWSLKVQLPRAPG
GVVGEAVAGAMSHAFGFTGGTLLLLIALAIGLSLYFRFSWLAVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREG
KVEEERVRIEDHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPPVSLLDPAPKTQESISADTLEFTSRLIEKKL
KDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNYMALELPNQRRQTVYLSEII
GSEVYAAAPSALTLSLGKDISGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVY
EGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKIPNPFSLTPEDPEPLGRLPNI
VVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAE
SLLGMGDMLYLPPGTGLPVRVHGAFVADDEVHRVVEKLKEQGEPNYVEGLLEGGTADGDEGSAGAGTGEAGAESDPLYDQ
AVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPVRDAE
>Mature_779_residues
MRGPFSLYGFMAKAPYSAQAQALPHRMSKLLMEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHISNWAGRVGAWT
ADIVLLLFGLSAYWLIVPLARRIAVNYRRITRHDALADEPERPIGWLTEIFAFVLVVLACDGIEALRMWSLKVQLPRAPG
GVVGEAVAGAMSHAFGFTGGTLLLLIALAIGLSLYFRFSWLAVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREG
KVEEERVRIEDHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPPVSLLDPAPKTQESISADTLEFTSRLIEKKL
KDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNYMALELPNQRRQTVYLSEII
GSEVYAAAPSALTLSLGKDISGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVY
EGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKIPNPFSLTPEDPEPLGRLPNI
VVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAE
SLLGMGDMLYLPPGTGLPVRVHGAFVADDEVHRVVEKLKEQGEPNYVEGLLEGGTADGDEGSAGAGTGEAGAESDPLYDQ
AVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPVRDAE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=494, Percent_Identity=64.17004048583, Blast_Score=614, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 84861; Mature: 84861

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGPFSLYGFMAKAPYSAQAQALPHRMSKLLMEIRWILQVALCAFLVMALLSYSRRDPSW
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
THAAQVDHISNWAGRVGAWTADIVLLLFGLSAYWLIVPLARRIAVNYRRITRHDALADEP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ERPIGWLTEIFAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGAMSHAFGFTGG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHH
TLLLLIALAIGLSLYFRFSWLAVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KVEEERVRIEDHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPPVSLLDPAPKT
CCCHHHEEECCCCCEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCCCCC
QESISADTLEFTSRLIEKKLKDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHH
LARSLSLVSIRVVETIPGKNYMALELPNQRRQTVYLSEIIGSEVYAAAPSALTLSLGKDI
HHHHHHHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCHHHHCCCCEEEEECCCCC
SGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVY
CCCCHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHH
EGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKI
HCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHCC
PNPFSLTPEDPEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILAT
CCCCCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
QRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLYLPPGTGLPVR
CCCCHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCCEE
VHGAFVADDEVHRVVEKLKEQGEPNYVEGLLEGGTADGDEGSAGAGTGEAGAESDPLYDQ
EEEEEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPVRDAE
HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEECCCC
>Mature Secondary Structure
MRGPFSLYGFMAKAPYSAQAQALPHRMSKLLMEIRWILQVALCAFLVMALLSYSRRDPSW
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
THAAQVDHISNWAGRVGAWTADIVLLLFGLSAYWLIVPLARRIAVNYRRITRHDALADEP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ERPIGWLTEIFAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGAMSHAFGFTGG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHH
TLLLLIALAIGLSLYFRFSWLAVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KVEEERVRIEDHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPPVSLLDPAPKT
CCCHHHEEECCCCCEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCCCCC
QESISADTLEFTSRLIEKKLKDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHH
LARSLSLVSIRVVETIPGKNYMALELPNQRRQTVYLSEIIGSEVYAAAPSALTLSLGKDI
HHHHHHHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCHHHHCCCCEEEEECCCCC
SGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVY
CCCCHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHH
EGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKI
HCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHCC
PNPFSLTPEDPEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILAT
CCCCCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
QRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLYLPPGTGLPVR
CCCCHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCCEE
VHGAFVADDEVHRVVEKLKEQGEPNYVEGLLEGGTADGDEGSAGAGTGEAGAESDPLYDQ
EEEEEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPVRDAE
HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]