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The map label for this gene is arsC [H]

Identifier: 161525487

GI number: 161525487

Start: 2529040

End: 2529528

Strand: Reverse

Name: arsC [H]

Synonym: Bmul_2317

Alternate gene names: 161525487

Gene position: 2529528-2529040 (Counterclockwise)

Preceding gene: 161525488

Following gene: 161525486

Centisome position: 73.35

GC content: 63.8

Gene sequence:

>489_bases
ATGACCACCTACAACGCCTTGTTTATCTGCACGGGCAACTCTGCCCGCTCCATCCTTGCCGAAGGCTTGCTCAACGAGCT
AGGCCAAGGTCGCTTCCACGCCTATTCCGCCGGCAGTCACCCAAAGGGCGAGGTTCATCCGCTGGCGCTTGCCACGCTGG
AGCGGCTGCGCCTGCCGAAAACCGGCTACCGCAGCAAGAGCTGGGACGAGTTCATGAAACCCGATGCGCCGGTGTTCGAC
TTCATCTTCACCGTCTGCGACAACGCCGCCGGCGAGGCGTGTCCGCTGTGGCCGGGCAAGCCCGTGTCGGCCCACTGGGG
CGTACCCGACCCGGTTGCGGTCGAAGGCACCGATGAACAGCAGCGCAAAGCGTTCCTCGATGCAGCGATCACGCTGCGTC
GGCGCATCGAGCTATTCCTGTCGCTGCCATTGCAGCGTCTCGATGCCATGTCGTTGCAGCGCGAGCTGCGCGAAATTGGC
CGCCAGTGA

Upstream 100 bases:

>100_bases
GCCCGGATGAACGGTTTGCTCGGCTACATGACCGAGCACTGCTGCCAAGGCGGTGTCTGCGAGGTTTCCGACACAACCAC
CCGCTGCGACTGTTGACGCC

Downstream 100 bases:

>100_bases
GGCTCGCCCGATGACCGCAACCGATACCGCCGGCCCCGCGCCGGCCACCTCCGCCATGAGCGTCTTCGAGCGTTACCTGA
CGGTGTGGGTGGCGCTGTGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTTYNALFICTGNSARSILAEGLLNELGQGRFHAYSAGSHPKGEVHPLALATLERLRLPKTGYRSKSWDEFMKPDAPVFD
FIFTVCDNAAGEACPLWPGKPVSAHWGVPDPVAVEGTDEQQRKAFLDAAITLRRRIELFLSLPLQRLDAMSLQRELREIG
RQ

Sequences:

>Translated_162_residues
MTTYNALFICTGNSARSILAEGLLNELGQGRFHAYSAGSHPKGEVHPLALATLERLRLPKTGYRSKSWDEFMKPDAPVFD
FIFTVCDNAAGEACPLWPGKPVSAHWGVPDPVAVEGTDEQQRKAFLDAAITLRRRIELFLSLPLQRLDAMSLQRELREIG
RQ
>Mature_161_residues
TTYNALFICTGNSARSILAEGLLNELGQGRFHAYSAGSHPKGEVHPLALATLERLRLPKTGYRSKSWDEFMKPDAPVFDF
IFTVCDNAAGEACPLWPGKPVSAHWGVPDPVAVEGTDEQQRKAFLDAAITLRRRIELFLSLPLQRLDAMSLQRELREIGR
Q

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18051; Mature: 17920

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYNALFICTGNSARSILAEGLLNELGQGRFHAYSAGSHPKGEVHPLALATLERLRLPK
CCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCC
TGYRSKSWDEFMKPDAPVFDFIFTVCDNAAGEACPLWPGKPVSAHWGVPDPVAVEGTDEQ
CCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHH
QRKAFLDAAITLRRRIELFLSLPLQRLDAMSLQRELREIGRQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTYNALFICTGNSARSILAEGLLNELGQGRFHAYSAGSHPKGEVHPLALATLERLRLPK
CCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCC
TGYRSKSWDEFMKPDAPVFDFIFTVCDNAAGEACPLWPGKPVSAHWGVPDPVAVEGTDEQ
CCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHH
QRKAFLDAAITLRRRIELFLSLPLQRLDAMSLQRELREIGRQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]