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The map label for this gene is yycG [H]

Identifier: 161525049

GI number: 161525049

Start: 2051350

End: 2053734

Strand: Reverse

Name: yycG [H]

Synonym: Bmul_1877

Alternate gene names: 161525049

Gene position: 2053734-2051350 (Counterclockwise)

Preceding gene: 161525050

Following gene: 161525048

Centisome position: 59.56

GC content: 69.85

Gene sequence:

>2385_bases
ATGAAAGCCGATTCCGTTTCTCCGCGGCGGCAGCTCGGGCGCCGCTTCCTGCTCGAATGGATCGCGATCGGCTGTCTCGG
GATCGCGGTGATCTGCGCATGCGCGCTCGGCCGCGCATCGTCGAGCGTCGACGGGCTGATCTACGACCGGCTGCTGATGC
TGCGCAGCCTGCCGCTGTCGCCGGACGTCGTGGTCGTCGACATCGACAACCAGAGCGTGTCCGCGCTCGGCCGCTGGCCG
TGGTCGCGCAACGTGCACGCGCGGCTGCTCGACACGCTCGCGCGTGCGCAGCCGGCGGCCGTGGTCTACGACGTGCTGTT
TACCGAGCCGTCTCCCGACGATCGCGCGTTCGCCGACGCGATGGCGCGCGTGCCGACCTTCCTGCCGGTGCTGCTGAGCC
CCGAGCAGGACGGCAAGCGCGCGCTCGATCCGCCGGTCGCGGCGCTCGCCGCGCGCGCAATGGGGCTCGGGCATATCAAT
CTCGAAGTCGATCCGGACGGCATCGTGCGCAGCGTCGCGCTGTTCGAGGACGACGGCCGCACGCGCTGGCCGCAGCTGAT
GGTGCCCGTCTATCGCGCGATCACGGCCGGCACGCTGCATCCGGCCGGCGGCGCGCCGGGCCCGCGCGCGCACGACCTCT
CGCGCGACGCGACCGGCGAAGGCCGCTATCTGATTCCGTTCAGCCGCAATACGCCCGCGTATCCGACGCTGTCGTTCGAC
GACGTGCTCGAAGGGCGCGTGAAGCCCGATGCGCTGCGCGGCAAGATCGTCGTCGTCGGCGTGACCGCGTCGGGGCTCTA
CGACCGCTTCGCGACGCCCGTGTCCGGCGATTTCGGCCCGCTCGCCGGCGTCTACATCCACGCGAGCGTGCTCGACATGC
TGACGACCGGCTCCGCGATTTCGCCGGTCTCGCGACCGGTGCTGTTCGCCGCGTCGCTCTTGCCGCTCGCGGCGCTGCTC
GGCGGTTTCCTGATGCTGTCGCCGTGGCGCGCGCTGCTGCTGACGCTGAGCCTCGCGGCGCTCGCGGTGATCGCGAGCAT
CGCGCTGCTGTTCGAGGCGCGCGTCTGGCTGTCGCCGGCGCCGGCCGTGTTCGGGCTGATCGCCGTGTATCCGATCTGGA
ACTGGCGGCGCCTCGAGATGACGATGTCGTACCTGCGCCGCGAGCTGCAGCGCCTTGCCGACGAACCGCATCTGCTGCCC
GAGGCGCCGCGCGCGCGCAGCGTCGGCGGCGACGTGCTCGAGCGGCAGATGGCGCTGATGGCACAGGCCGCGCAGCGTGT
GCAGGACATGAAGCGCTTCGTGTGGGACAGCCTCGACAGCATGCCGGAACCGATCTTCGTGACCGACCTGGCCGGCACCG
TGCTGATCGCGAACCACGCGGCCAAGCGCTACGGCTCGCGGCTTGCGCTGCCGCTGCCGGAAGGGCGGCCGCTGCGCGCG
GCGCTCGGCGAGCTGACCTTCGTGAAGACCGTCGACGGCAACGCGGAGCACGACGTCGCGATCCGCGACAGCTGGCCGGC
CGCGCTCGACCCGACGCTCGCGGCCGAGCAGGACGTGATGGCGCGCGGCATCGAGGTGCGCGATCGCGACGGGCTCGACC
ATCTGCTACGCTACGCAGCGTGTACGAACGCGCAGGGTCACGTGACGGGCTGGATCGCGGGCCTCGTCGACGTCACCGAG
CTGCACGCGGCCGAGCGGCAGCGCGAGGAAGCGCTGCATCTGCTGTCGCACGACATGCGCTCGCCGCAGTCGTCGATTCT
CGCGCTCGTCGAGATCGAGCGCGACCGCGTCGAGTCCGACACGATGCGTGCGCTGCTCGCGCGGATCGAACGCTATGCGC
ACCGTGCGCTGTCGCTTGCCGACGAGTTCGTGCAGCTCGCGCGCGCCGAGTCGCAGGCCTATCAGCTCGAGACGACGAGC
CTCGTCGACGTGCTGATCGACGCGAGCGACGAAGTGTGGCCGCAGGCGCAGGCGAAGCGCATCCGCATCGATACCGACGT
CGGCACGGACATGTGCTGGGTCAGGGCGGACCGCTCGCTGATCACGCGCGCGTTCGTCAACGTGCTGAACAACGCGGTCA
AATATAGTCCGTCCGACACGACGATCACGTGTACGCTGACGGTCGAACACGCGTCGAAACGGATGTTCTGTACGATTCGC
GACCAGGGGTACGGCATTGCGCCGGAAGATCAGCGACATCTGTTCGAGCGTTTCAAACGATTCCATGCGGGCGAGCGGCC
CGAGATCTCGGGCTCCGGGCTCGGCATGGCATTCGTGAAGACGGTCGTCACGCGCCACGGCGGCAGCGTGTCGGTCGACA
GCGAAGTGGGCGTCGGCACCGCGGTGACGGTGTCGCTGCCCGCGATCGACGAGCCGTCCGCCTGA

Upstream 100 bases:

>100_bases
TATTTCTGGGCCGTGACGGTCGAGGAGTTCTCGGGCGGCAAGTTCTACGAGAAGACGAGCCCGGTCGGTGCGTTTACGTT
GTCGCGTTGATCCGCGGCAG

Downstream 100 bases:

>100_bases
CAGGGCCGGGCACGACGGCAGGCATTGGGGGAAGTCATGAGAAAGCAATGGGCAGCGACCGCGCTGGCGGCGTCGCTGTT
GACGGGTTGCGCCGGCGTCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MKADSVSPRRQLGRRFLLEWIAIGCLGIAVICACALGRASSSVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WSRNVHARLLDTLARAQPAAVVYDVLFTEPSPDDRAFADAMARVPTFLPVLLSPEQDGKRALDPPVAALAARAMGLGHIN
LEVDPDGIVRSVALFEDDGRTRWPQLMVPVYRAITAGTLHPAGGAPGPRAHDLSRDATGEGRYLIPFSRNTPAYPTLSFD
DVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGDFGPLAGVYIHASVLDMLTTGSAISPVSRPVLFAASLLPLAALL
GGFLMLSPWRALLLTLSLAALAVIASIALLFEARVWLSPAPAVFGLIAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLP
EAPRARSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLRA
ALGELTFVKTVDGNAEHDVAIRDSWPAALDPTLAAEQDVMARGIEVRDRDGLDHLLRYAACTNAQGHVTGWIAGLVDVTE
LHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESDTMRALLARIERYAHRALSLADEFVQLARAESQAYQLETTS
LVDVLIDASDEVWPQAQAKRIRIDTDVGTDMCWVRADRSLITRAFVNVLNNAVKYSPSDTTITCTLTVEHASKRMFCTIR
DQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA

Sequences:

>Translated_794_residues
MKADSVSPRRQLGRRFLLEWIAIGCLGIAVICACALGRASSSVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WSRNVHARLLDTLARAQPAAVVYDVLFTEPSPDDRAFADAMARVPTFLPVLLSPEQDGKRALDPPVAALAARAMGLGHIN
LEVDPDGIVRSVALFEDDGRTRWPQLMVPVYRAITAGTLHPAGGAPGPRAHDLSRDATGEGRYLIPFSRNTPAYPTLSFD
DVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGDFGPLAGVYIHASVLDMLTTGSAISPVSRPVLFAASLLPLAALL
GGFLMLSPWRALLLTLSLAALAVIASIALLFEARVWLSPAPAVFGLIAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLP
EAPRARSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLRA
ALGELTFVKTVDGNAEHDVAIRDSWPAALDPTLAAEQDVMARGIEVRDRDGLDHLLRYAACTNAQGHVTGWIAGLVDVTE
LHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESDTMRALLARIERYAHRALSLADEFVQLARAESQAYQLETTS
LVDVLIDASDEVWPQAQAKRIRIDTDVGTDMCWVRADRSLITRAFVNVLNNAVKYSPSDTTITCTLTVEHASKRMFCTIR
DQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA
>Mature_794_residues
MKADSVSPRRQLGRRFLLEWIAIGCLGIAVICACALGRASSSVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WSRNVHARLLDTLARAQPAAVVYDVLFTEPSPDDRAFADAMARVPTFLPVLLSPEQDGKRALDPPVAALAARAMGLGHIN
LEVDPDGIVRSVALFEDDGRTRWPQLMVPVYRAITAGTLHPAGGAPGPRAHDLSRDATGEGRYLIPFSRNTPAYPTLSFD
DVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGDFGPLAGVYIHASVLDMLTTGSAISPVSRPVLFAASLLPLAALL
GGFLMLSPWRALLLTLSLAALAVIASIALLFEARVWLSPAPAVFGLIAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLP
EAPRARSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLRA
ALGELTFVKTVDGNAEHDVAIRDSWPAALDPTLAAEQDVMARGIEVRDRDGLDHLLRYAACTNAQGHVTGWIAGLVDVTE
LHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESDTMRALLARIERYAHRALSLADEFVQLARAESQAYQLETTS
LVDVLIDASDEVWPQAQAKRIRIDTDVGTDMCWVRADRSLITRAFVNVLNNAVKYSPSDTTITCTLTVEHASKRMFCTIR
DQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=384, Percent_Identity=26.0416666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=28.3783783783784, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=27.5423728813559, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=26.1603375527426, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=23.7354085603113, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=244, Percent_Identity=28.2786885245902, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=27.2340425531915, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=227, Percent_Identity=21.5859030837004, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=23.0088495575221, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=25.1046025104602, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=26.2910798122066, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86611; Mature: 86611

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADSVSPRRQLGRRFLLEWIAIGCLGIAVICACALGRASSSVDGLIYDRLLMLRSLPLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PDVVVVDIDNQSVSALGRWPWSRNVHARLLDTLARAQPAAVVYDVLFTEPSPDDRAFADA
CCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHCCCHHEEEEEHCCCCCCCHHHHHHH
MARVPTFLPVLLSPEQDGKRALDPPVAALAARAMGLGHINLEVDPDGIVRSVALFEDDGR
HHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHEEHEEECCCC
TRWPQLMVPVYRAITAGTLHPAGGAPGPRAHDLSRDATGEGRYLIPFSRNTPAYPTLSFD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHH
DVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGDFGPLAGVYIHASVLDMLTTGSAI
HHHCCCCCCHHHCCEEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
SPVSRPVLFAASLLPLAALLGGFLMLSPWRALLLTLSLAALAVIASIALLFEARVWLSPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PAVFGLIAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLPEAPRARSVGGDVLERQMALM
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLRA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHHCCEEEEECCCCCCHHH
ALGELTFVKTVDGNAEHDVAIRDSWPAALDPTLAAEQDVMARGIEVRDRDGLDHLLRYAA
HHCCEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
CTNAQGHVTGWIAGLVDVTELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHCCHH
TMRALLARIERYAHRALSLADEFVQLARAESQAYQLETTSLVDVLIDASDEVWPQAQAKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCCCCCE
IRIDTDVGTDMCWVRADRSLITRAFVNVLNNAVKYSPSDTTITCTLTVEHASKRMFCTIR
EEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEE
DQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCE
AVTVSLPAIDEPSA
EEEEEECCCCCCCC
>Mature Secondary Structure
MKADSVSPRRQLGRRFLLEWIAIGCLGIAVICACALGRASSSVDGLIYDRLLMLRSLPLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PDVVVVDIDNQSVSALGRWPWSRNVHARLLDTLARAQPAAVVYDVLFTEPSPDDRAFADA
CCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHCCCHHEEEEEHCCCCCCCHHHHHHH
MARVPTFLPVLLSPEQDGKRALDPPVAALAARAMGLGHINLEVDPDGIVRSVALFEDDGR
HHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHEEHEEECCCC
TRWPQLMVPVYRAITAGTLHPAGGAPGPRAHDLSRDATGEGRYLIPFSRNTPAYPTLSFD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHH
DVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGDFGPLAGVYIHASVLDMLTTGSAI
HHHCCCCCCHHHCCEEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
SPVSRPVLFAASLLPLAALLGGFLMLSPWRALLLTLSLAALAVIASIALLFEARVWLSPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PAVFGLIAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLPEAPRARSVGGDVLERQMALM
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLRA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHHCCEEEEECCCCCCHHH
ALGELTFVKTVDGNAEHDVAIRDSWPAALDPTLAAEQDVMARGIEVRDRDGLDHLLRYAA
HHCCEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
CTNAQGHVTGWIAGLVDVTELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHCCHH
TMRALLARIERYAHRALSLADEFVQLARAESQAYQLETTSLVDVLIDASDEVWPQAQAKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCCCCCE
IRIDTDVGTDMCWVRADRSLITRAFVNVLNNAVKYSPSDTTITCTLTVEHASKRMFCTIR
EEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEE
DQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCE
AVTVSLPAIDEPSA
EEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]