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The map label for this gene is pheS [H]

Identifier: 161524948

GI number: 161524948

Start: 1964158

End: 1965195

Strand: Reverse

Name: pheS [H]

Synonym: Bmul_1775

Alternate gene names: 161524948

Gene position: 1965195-1964158 (Counterclockwise)

Preceding gene: 161524949

Following gene: 161524947

Centisome position: 56.99

GC content: 63.68

Gene sequence:

>1038_bases
ATGACGTTGGAAATGATGGGATCTATGGATCTGGACCAGATTGTCGCCGACGCGCAGCAGTCCTTCGAACGGGCTGCCGA
CATCACCACGCTCGAAAACGAGAAAGCACGATTTCTCGGCAAGTCGGGCGCGCTGACCGAGTTGCTGAAGGGCCTCGGCA
AGCTCGATCCCGAAGCACGCAAGACCGAAGGCGCACGCATCAACGTCGCGAAGCAGCAGGTTGAAGCCGCGCTGACCGCA
CGCCGTCAGGCGCTTGCCGACGCGCTGCTGAACCAGCGCCTCGCCGCCGAAGCGATCGACGTCACGCTGCCCGGCCGCGG
TGCGGGCACCGGCACGCTGCACCCCGTGATGCGCACGTGGGAGCGCGTCGAACAGATTTTCCGCTCGATCGGTTTCGATG
TGGCCGACGGCCCCGAGATCGAGACCGACTGGTACAACTTCACGTCGCTGAACAGCCCGGAAAACCATCCGGCCCGGTCG
ATGCAGGACACCTTCTACGTCGAAGGCAAGGACGCCGACGGCCGCCCGCTGCTGCTGCGCACGCACACGAGCCCGATGCA
GGTGCGCTACGCGCGGATGAACCGTCCGCCGATCAAGGTGATCGCGCCGGGCCGCACGTACCGCGTCGACAGCGACGCGA
CGCATTCGCCGATGTTCAACCAGGTCGAAGGGCTGTGGATCGACGAGAACATCAGCTTTGCCGACCTCAAGGGCGTCTAT
ACCGACTTCCTGAAAAAATTCTTCGAGCGCGACGACATCCTCGTGCGCTTCCGTCCGTCGTACTTCCCGTTCACGGAACC
GTCGGCCGAGATCGACATGATGTTCGAGCACGGCAAGAACGCCGGCAAGTGGCTCGAGATCTCTGGCTCGGGGCAGGTGC
ATCCGACCGTGATCCGCAACATGGGCCTCGATCCCGAGCGCTACATCGGCTTCGCGTTCGGCAGCGGCCTCGAGCGTCTG
ACGATGCTGCGCTACGGCGTGCAGGATCTGCGCCTGTTCTTCGAGAACGATCTGCGCTTCCTGCGCCAGTTCGCGTAA

Upstream 100 bases:

>100_bases
CTGGGCCGCCCGAAGCGGGCCGAGCGCCCGGCGGGCAGCGAACGAAGCGTGCGTGAGGGCCGTTTTCTGTTGGCCGGACG
AATTCGCCGGTCAAGACCGA

Downstream 100 bases:

>100_bases
CGCGCGCCGCGCCGACATGTGCCCGCGCCGCTCCGACGATGGAGCGCCGGGCGTCGATCTAACCCGTTTCGAACGTAGAC
ATCCATGCAATTCCCTGAAT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTLEMMGSMDLDQIVADAQQSFERAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGARINVAKQQVEAALTA
RRQALADALLNQRLAAEAIDVTLPGRGAGTGTLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTSLNSPENHPARS
MQDTFYVEGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVY
TDFLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERL
TMLRYGVQDLRLFFENDLRFLRQFA

Sequences:

>Translated_345_residues
MTLEMMGSMDLDQIVADAQQSFERAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGARINVAKQQVEAALTA
RRQALADALLNQRLAAEAIDVTLPGRGAGTGTLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTSLNSPENHPARS
MQDTFYVEGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVY
TDFLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERL
TMLRYGVQDLRLFFENDLRFLRQFA
>Mature_344_residues
TLEMMGSMDLDQIVADAQQSFERAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGARINVAKQQVEAALTAR
RQALADALLNQRLAAEAIDVTLPGRGAGTGTLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTSLNSPENHPARSM
QDTFYVEGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYT
DFLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLT
MLRYGVQDLRLFFENDLRFLRQFA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=263, Percent_Identity=31.9391634980989, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI5729820, Length=290, Percent_Identity=31.0344827586207, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1788007, Length=334, Percent_Identity=57.185628742515, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI32563657, Length=264, Percent_Identity=32.9545454545455, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17508957, Length=265, Percent_Identity=32.8301886792453, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32566635, Length=275, Percent_Identity=32.3636363636364, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6321087, Length=267, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6325304, Length=94, Percent_Identity=40.4255319148936, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18858079, Length=300, Percent_Identity=30.3333333333333, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17137424, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 39050; Mature: 38919

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEMMGSMDLDQIVADAQQSFERAADITTLENEKARFLGKSGALTELLKGLGKLDPEAR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHCCCCCHHHHHHHHHCCCCHHH
KTEGARINVAKQQVEAALTARRQALADALLNQRLAAEAIDVTLPGRGAGTGTLHPVMRTW
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHH
ERVEQIFRSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTFYVEGKDADGRPLLLR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
THTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVY
ECCCCHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHCCCCEEEECCCCHHHHHHHH
TDFLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRN
HHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
MGLDPERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
CCCCHHHHEEEHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLEMMGSMDLDQIVADAQQSFERAADITTLENEKARFLGKSGALTELLKGLGKLDPEAR
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHCCCCCHHHHHHHHHCCCCHHH
KTEGARINVAKQQVEAALTARRQALADALLNQRLAAEAIDVTLPGRGAGTGTLHPVMRTW
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHH
ERVEQIFRSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTFYVEGKDADGRPLLLR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
THTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVY
ECCCCHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHCCCCEEEECCCCHHHHHHHH
TDFLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRN
HHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
MGLDPERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
CCCCHHHHEEEHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA