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The map label for this gene is ychM [C]

Identifier: 161524888

GI number: 161524888

Start: 1894816

End: 1896540

Strand: Reverse

Name: ychM [C]

Synonym: Bmul_1715

Alternate gene names: 161524888

Gene position: 1896540-1894816 (Counterclockwise)

Preceding gene: 161524889

Following gene: 161524882

Centisome position: 55.0

GC content: 69.91

Gene sequence:

>1725_bases
ATGACCACTGCGCCGATTCGTCCCGACGCCGGCCCGCAGCGCGCCGAGCATTTCGCCACGGCGCAGGCGTCGCCGTCGCG
CGCGCGCCGCTTCGCGCTCGATGCGCTGGCCGGCATATCGATCGCGGGCCTGCTGATTCCGGAGGCCGTCGCATATGCGG
GGCTCGCGAATCTGCCGCCGCAGGCGGGCCTGATCGCGCTGTTGTCGGGGCTCGTCGTCTATGCGCTCACGGGCAGCAGC
CGCTTCGCGATCGTCTCCTCGACATCGTCGTCGGCCGCGGTGCTTGCGGCCACCGTGTTCGCCGAATCGGGCGTCGCGCC
GGCTGCGCAGCTCGCGCTGGCCGCCGCACTCGTCGCGATGACGGGCGTGCTGTTGATACTCGCCGGCGCCGCGCGGCTCG
GCGGCATGTCGGATTTCGTCGCGCGGCCCGTGTTGCGCGGCTTCACGTTCGGACTCGCGCTGACGATCGTGCTCAAGCAG
TTGCCGAAAATGCTCGCGATTCCGGTGTCGCACAGCGATGCGCCGCGCGTCGCGCTCGATCTCGTCGCCGGCGTGCCGCA
CGCGAACGTTGCAAGCGTCGCGCTCGGCGCGGCCGCGCTCGCGCTGCTGTTCGTGCTCGGTCGCCGCTCGCGCGTGCCGG
CGACGCTCGTCGTGATCGTGTTGTCGATCGTGGCCGGCTATGTCGTCGACTGGCACCGCTACGGCATCGCAGTCGTCGGC
CATATCGATCTGAGCCGCGTCGCATTCGGATTGCCGCATCTCGACCGCAATGCGTGGACGCAGACGATCGAACTCGCGTT
CGCGCTGATGCTGATCCTGTATGCGGAATCGTACGGGTCGATCCGCGCCTTCGCGCTGAAGTACGGCGACAGCATTGCGC
CGAACCGCGACCTCGTCGCGCTCGGCTGCGCGAATCTGGTGTCGGGCCTGCTGCACGGCATGCCGGTCGGCGCCGGTTAT
TCGGCGACCTCGGCCAACGAGGCGGCCGGCGCGCAGACGCGCTTCGCCGGCCTGTGGGCGGCCGCCGTCGTCGCGCTGAT
CGTATGGCTACTGCTGCCGCAGCTCGCGCGCACGCCGGAGCCGGTGCTCGCGGCGATCGTGATCTTCGCGGTCAGCCATT
CGCTGCATCCGGCCGTGTTTCGGCCGTACTGGGCCTGGCATCGCGACCGGCTCGTCGTGATCGCCGCGCTGCTCGCGGTG
CTCGTGCTCGGCGTGCTGCAGGGGCTGCTCGCCGCGATCGGCGTGAGCCTGCTGCTGACGCTGCGCAAGCTGTCGGAGCC
GAACGTCAGCGTGCTCGGCAGGCTGCGCGACAGCCACGATTTCGTCGACATCGCGAGTCATGCGGATGCGCGGCCCGTGC
CCGGCGTGCTGATCGTGCGGCCGGAAGCGCAGTTGTTCTTCGCGAACGCAGACCGGATGCTCAATCGCGTCCGCGCCCTG
CTGAAAACGGCGCCTGACGTGCAGACGGTGATGCTGAGCCTCGAGGAAACGCCCGACGTCGACGGGACGACGATCGAGTC
GCTGCGCACGTTCGCGGCCGAATGCGCCGCGCACGGGCTGCGGTTCACGATCGTGCGGCTGAAGCTGCACGCGCTGCATG
CGTTGCGCCGCGCGGCCGACGATACGCTGCGCGACGATGCGTTGTCCGAGTTGAGCGTCGACGAGAGCCTGCAGCTCTGG
CAGGCACACGGTGCGGACGGTACGGAGGGCACCGCCCCGCGATGA

Upstream 100 bases:

>100_bases
ATCGCGCTGCGGCATGCGCACGATCAGGACGCGCGCTATCTGCCCGGCTGGTCGGGCGTGATCGCCGTCAAGCCGTGAGC
GGCGCACGCGCCGACCGACC

Downstream 100 bases:

>100_bases
GCCGCGGCGGCGCGGCCGCGACGCTCAGCCCGACAGCGCTGCGTCGGCTGCTGCGGCCGTGTCCGTATGCGCGGCGGTGC
GCACCAGTGCGTCGACCTCG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MTTAPIRPDAGPQRAEHFATAQASPSRARRFALDALAGISIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGSS
RFAIVSSTSSSAAVLAATVFAESGVAPAAQLALAAALVAMTGVLLILAGAARLGGMSDFVARPVLRGFTFGLALTIVLKQ
LPKMLAIPVSHSDAPRVALDLVAGVPHANVASVALGAAALALLFVLGRRSRVPATLVVIVLSIVAGYVVDWHRYGIAVVG
HIDLSRVAFGLPHLDRNAWTQTIELAFALMLILYAESYGSIRAFALKYGDSIAPNRDLVALGCANLVSGLLHGMPVGAGY
SATSANEAAGAQTRFAGLWAAAVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWAWHRDRLVVIAALLAV
LVLGVLQGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDIASHADARPVPGVLIVRPEAQLFFANADRMLNRVRAL
LKTAPDVQTVMLSLEETPDVDGTTIESLRTFAAECAAHGLRFTIVRLKLHALHALRRAADDTLRDDALSELSVDESLQLW
QAHGADGTEGTAPR

Sequences:

>Translated_574_residues
MTTAPIRPDAGPQRAEHFATAQASPSRARRFALDALAGISIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGSS
RFAIVSSTSSSAAVLAATVFAESGVAPAAQLALAAALVAMTGVLLILAGAARLGGMSDFVARPVLRGFTFGLALTIVLKQ
LPKMLAIPVSHSDAPRVALDLVAGVPHANVASVALGAAALALLFVLGRRSRVPATLVVIVLSIVAGYVVDWHRYGIAVVG
HIDLSRVAFGLPHLDRNAWTQTIELAFALMLILYAESYGSIRAFALKYGDSIAPNRDLVALGCANLVSGLLHGMPVGAGY
SATSANEAAGAQTRFAGLWAAAVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWAWHRDRLVVIAALLAV
LVLGVLQGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDIASHADARPVPGVLIVRPEAQLFFANADRMLNRVRAL
LKTAPDVQTVMLSLEETPDVDGTTIESLRTFAAECAAHGLRFTIVRLKLHALHALRRAADDTLRDDALSELSVDESLQLW
QAHGADGTEGTAPR
>Mature_573_residues
TTAPIRPDAGPQRAEHFATAQASPSRARRFALDALAGISIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGSSR
FAIVSSTSSSAAVLAATVFAESGVAPAAQLALAAALVAMTGVLLILAGAARLGGMSDFVARPVLRGFTFGLALTIVLKQL
PKMLAIPVSHSDAPRVALDLVAGVPHANVASVALGAAALALLFVLGRRSRVPATLVVIVLSIVAGYVVDWHRYGIAVVGH
IDLSRVAFGLPHLDRNAWTQTIELAFALMLILYAESYGSIRAFALKYGDSIAPNRDLVALGCANLVSGLLHGMPVGAGYS
ATSANEAAGAQTRFAGLWAAAVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPAVFRPYWAWHRDRLVVIAALLAVL
VLGVLQGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDIASHADARPVPGVLIVRPEAQLFFANADRMLNRVRALL
KTAPDVQTVMLSLEETPDVDGTTIESLRTFAAECAAHGLRFTIVRLKLHALHALRRAADDTLRDDALSELSVDESLQLWQ
AHGADGTEGTAPR

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721259, Length=458, Percent_Identity=26.8558951965066, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI94721255, Length=458, Percent_Identity=26.8558951965066, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI94721253, Length=458, Percent_Identity=26.8558951965066, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI94721257, Length=458, Percent_Identity=26.8558951965066, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI39752683, Length=487, Percent_Identity=24.2299794661191, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI45827800, Length=487, Percent_Identity=24.2299794661191, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI217272867, Length=506, Percent_Identity=22.7272727272727, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI16418413, Length=506, Percent_Identity=22.7272727272727, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI47131207, Length=505, Percent_Identity=26.5346534653465, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI20336272, Length=505, Percent_Identity=26.5346534653465, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI269784651, Length=484, Percent_Identity=23.9669421487603, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4557535, Length=509, Percent_Identity=24.950884086444, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI45827802, Length=445, Percent_Identity=23.5955056179775, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI100913030, Length=521, Percent_Identity=21.3051823416507, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4505697, Length=485, Percent_Identity=21.4432989690722, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI20336282, Length=493, Percent_Identity=22.920892494929, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI16306483, Length=493, Percent_Identity=22.920892494929, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI262206105, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206075, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206069, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206063, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI65506789, Length=371, Percent_Identity=28.0323450134771, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI16418457, Length=509, Percent_Identity=21.4145383104126, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI301601599, Length=509, Percent_Identity=21.4145383104126, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081859, Length=196, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551690, Length=520, Percent_Identity=24.8076923076923, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI86564876, Length=531, Percent_Identity=22.2222222222222, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI86564196, Length=499, Percent_Identity=23.4468937875752, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17566848, Length=573, Percent_Identity=24.4328097731239, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI86565215, Length=503, Percent_Identity=23.4592445328032, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193203292, Length=495, Percent_Identity=23.030303030303, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562578, Length=482, Percent_Identity=24.4813278008299, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325260, Length=494, Percent_Identity=23.0769230769231, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323121, Length=481, Percent_Identity=21.4137214137214, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24651449, Length=446, Percent_Identity=26.9058295964126, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24649801, Length=488, Percent_Identity=24.5901639344262, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666186, Length=406, Percent_Identity=25.615763546798, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21358229, Length=454, Percent_Identity=25.9911894273128, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24663084, Length=445, Percent_Identity=25.3932584269663, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357695, Length=445, Percent_Identity=25.3932584269663, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19922482, Length=567, Percent_Identity=21.6931216931217, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI85815873, Length=427, Percent_Identity=24.824355971897, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21358633, Length=574, Percent_Identity=22.9965156794425, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647160, Length=242, Percent_Identity=21.900826446281, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355087, Length=242, Percent_Identity=21.900826446281, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60198; Mature: 60067

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPIRPDAGPQRAEHFATAQASPSRARRFALDALAGISIAGLLIPEAVAYAGLANLPP
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVFAESGVAPAAQLALAAALVAM
CCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TGVLLILAGAARLGGMSDFVARPVLRGFTFGLALTIVLKQLPKMLAIPVSHSDAPRVALD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHH
LVAGVPHANVASVALGAAALALLFVLGRRSRVPATLVVIVLSIVAGYVVDWHRYGIAVVG
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
HIDLSRVAFGLPHLDRNAWTQTIELAFALMLILYAESYGSIRAFALKYGDSIAPNRDLVA
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCCCHH
LGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRFAGLWAAAVVALIVWLLLPQLARTPE
HHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
PVLAAIVIFAVSHSLHPAVFRPYWAWHRDRLVVIAALLAVLVLGVLQGLLAAIGVSLLLT
HHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRKLSEPNVSVLGRLRDSHDFVDIASHADARPVPGVLIVRPEAQLFFANADRMLNRVRAL
HHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHH
LKTAPDVQTVMLSLEETPDVDGTTIESLRTFAAECAAHGLRFTIVRLKLHALHALRRAAD
HHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DTLRDDALSELSVDESLQLWQAHGADGTEGTAPR
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTAPIRPDAGPQRAEHFATAQASPSRARRFALDALAGISIAGLLIPEAVAYAGLANLPP
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVFAESGVAPAAQLALAAALVAM
CCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TGVLLILAGAARLGGMSDFVARPVLRGFTFGLALTIVLKQLPKMLAIPVSHSDAPRVALD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHH
LVAGVPHANVASVALGAAALALLFVLGRRSRVPATLVVIVLSIVAGYVVDWHRYGIAVVG
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
HIDLSRVAFGLPHLDRNAWTQTIELAFALMLILYAESYGSIRAFALKYGDSIAPNRDLVA
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCCCHH
LGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRFAGLWAAAVVALIVWLLLPQLARTPE
HHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
PVLAAIVIFAVSHSLHPAVFRPYWAWHRDRLVVIAALLAVLVLGVLQGLLAAIGVSLLLT
HHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRKLSEPNVSVLGRLRDSHDFVDIASHADARPVPGVLIVRPEAQLFFANADRMLNRVRAL
HHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHH
LKTAPDVQTVMLSLEETPDVDGTTIESLRTFAAECAAHGLRFTIVRLKLHALHALRRAAD
HHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DTLRDDALSELSVDESLQLWQAHGADGTEGTAPR
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]