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The map label for this gene is ychM [C]

Identifier: 161524878

GI number: 161524878

Start: 1881044

End: 1882789

Strand: Reverse

Name: ychM [C]

Synonym: Bmul_1705

Alternate gene names: 161524878

Gene position: 1882789-1881044 (Counterclockwise)

Preceding gene: 161524880

Following gene: 161524875

Centisome position: 54.6

GC content: 68.21

Gene sequence:

>1746_bases
GTGGCTAAGGTCGGCATCGTACGGCTAGGCAGCGACATCGCGCGCTACGTGCCCGGTATCGCATGGATCCGCACGTACCG
GATCGCGTGGCTACCGGGCGACGCAATCGCGGGCGCGGCCCTCAGCGCCGTCTTGGTGCCGGCCGGCATGGCCTACGCGA
TCGCGTCCGGGCTTTCCGCCGCGTCGGGACTCTATGCGTCGATTGCCGCACTGGTCGCCTACGCCGTGTTCGGGCCGAGC
CGCGTCCTCGTGCTCGGGCCCGATTCCGCGCTGATTGCATTGATCGCGGCGAGCGTCGTGCCGCTCGCGCACGGCAATGC
CGCGCATGCCGCCGCGCTCGCAGGCGCGCTGGCGCTGCTCTCCGGCACGCTCTGTCTGGCCGTCGGCCTGTTCCGGCTCG
GCTTCGTCACCGATCTGCTCTCCATGCCGATCCGCTACGGCTATCTGAACGGTATCGTCGTCACGATCATCGTCAGCCAG
CTGCCGAAGCTGCTCGGCCTGAAGGTGCACGAAGCGGCGATTCCGCAGCAACTGCGCGAGCTGGCAACGGCCGTCGCTGC
CGGAAAAACGAATCTCGCGGCCTTGTCGATCGGCGTCCTGTCGCTTGCCGTGATCCTCGCGTTCAAACGCTGGATGCCGA
AAATGCCGGGCGTGCTGGTTGCCGTGGTCGTCGCGACCGTCGCGGCTGCCTATTTCGATTTGGCGGCGCGGGCCGGTGTC
GGCGTGGTAGGCACCTTGCCGCGCGGGCTGCCGGTGCCCGAATTTCCGGCGCTGGCGGCGAAGGAATGGCTTGCACTACC
GGCAAGTGCCGCCGCCATCGCGCTGGTGTCGTTGACGGACCTCAGCATGCTGTCGCAGATATACGGGCTGCGCAGCGGGC
AGGGCGTCGACCGCAATCGCGAATGCGTGGCGCTCGGCGTCGCGAATGTCGCGGCCGGTCTGTTCCAGGGCTTTGCGGTC
GCGGCCAGCGGATCGCGCACGCCCGTCGCGGAGGACGCGGGCGCGAAGAGTCAGGCGTGCGGCCTGATTGCCGCACTCAT
CGTCGCGGCGTTGCTGCTTTCCGTCCCGCAGGCGTTGCGCGATACGCCGCAAGCCACGCTCGGCGCCGTGGTCGTCGCCG
CGTCGCTGTCGTTGATCGAAATCACGGGGCTGCGGCGGCTTTACCGGCTGCGTCGTCCGGAATTCGTGCAGTCGCTCGCG
TGCTTTGTCGGCGTCGTAGTGTGGGGTGTCGTGACCGGCGTGGGGATCGCACTCGGGCTGGCCGTGCTGGCGTTCCTGTG
GCGCGCGTGGCGCCCTTACTCAGCGGTGCTCGGCCGGCGCGACGGCGTGAAGGGCTATCACGACATCGCGCGGCATCCGG
ACGCGCGGCGCGTCCCCGGGCTGGTTCTGCTGCGCTGGGATGCGCCGTTGTTCTTCGCGAATGCGGAAATCTTTCACGAA
CGCGTGTTGACGGCGGCGCGCGAGGCGCCCACGCGCACGCGGTGGGTTGCGATCGCGGCCGAGCCGGTGACGGATATCGA
CGTCACCGCAGCCGACATGCTCGCGAGGCTCGACGACGAACTCCACGATGCGGACGTGCAGCTCTGCTTCGCCGAGCTCA
AGGGGCCCGTCAAGGACAGCCTGAAGCGATATGGGTTGTACGAGCGAATCGGCGAAGACCACTTCCTGCCGACGCTCGGC
GAAACGGTGTCGGCGTATCTGAAATCGCATCCGGTGGACTGGCACGATTGGGAAGGCGGAGGGTGA

Upstream 100 bases:

>100_bases
GGACTTGCTGCGCAGGGACGTCCGGAATGACCGCTCGCCGCCATGGAACCACGAGATCCGAAAGCCCACGACCGTGCCGC
GTTCCTCGGGAGCAAGACGT

Downstream 100 bases:

>100_bases
GTGATCGCAACCGGACGGCGGCGACGCGTTGCTGGCAGCGTAGCATCATGCGTCGCGTCGATAGTGGACGACTGCGCCGG
TGTTCGGCGCGACGGGATTG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MAKVGIVRLGSDIARYVPGIAWIRTYRIAWLPGDAIAGAALSAVLVPAGMAYAIASGLSAASGLYASIAALVAYAVFGPS
RVLVLGPDSALIALIAASVVPLAHGNAAHAAALAGALALLSGTLCLAVGLFRLGFVTDLLSMPIRYGYLNGIVVTIIVSQ
LPKLLGLKVHEAAIPQQLRELATAVAAGKTNLAALSIGVLSLAVILAFKRWMPKMPGVLVAVVVATVAAAYFDLAARAGV
GVVGTLPRGLPVPEFPALAAKEWLALPASAAAIALVSLTDLSMLSQIYGLRSGQGVDRNRECVALGVANVAAGLFQGFAV
AASGSRTPVAEDAGAKSQACGLIAALIVAALLLSVPQALRDTPQATLGAVVVAASLSLIEITGLRRLYRLRRPEFVQSLA
CFVGVVVWGVVTGVGIALGLAVLAFLWRAWRPYSAVLGRRDGVKGYHDIARHPDARRVPGLVLLRWDAPLFFANAEIFHE
RVLTAAREAPTRTRWVAIAAEPVTDIDVTAADMLARLDDELHDADVQLCFAELKGPVKDSLKRYGLYERIGEDHFLPTLG
ETVSAYLKSHPVDWHDWEGGG

Sequences:

>Translated_581_residues
MAKVGIVRLGSDIARYVPGIAWIRTYRIAWLPGDAIAGAALSAVLVPAGMAYAIASGLSAASGLYASIAALVAYAVFGPS
RVLVLGPDSALIALIAASVVPLAHGNAAHAAALAGALALLSGTLCLAVGLFRLGFVTDLLSMPIRYGYLNGIVVTIIVSQ
LPKLLGLKVHEAAIPQQLRELATAVAAGKTNLAALSIGVLSLAVILAFKRWMPKMPGVLVAVVVATVAAAYFDLAARAGV
GVVGTLPRGLPVPEFPALAAKEWLALPASAAAIALVSLTDLSMLSQIYGLRSGQGVDRNRECVALGVANVAAGLFQGFAV
AASGSRTPVAEDAGAKSQACGLIAALIVAALLLSVPQALRDTPQATLGAVVVAASLSLIEITGLRRLYRLRRPEFVQSLA
CFVGVVVWGVVTGVGIALGLAVLAFLWRAWRPYSAVLGRRDGVKGYHDIARHPDARRVPGLVLLRWDAPLFFANAEIFHE
RVLTAAREAPTRTRWVAIAAEPVTDIDVTAADMLARLDDELHDADVQLCFAELKGPVKDSLKRYGLYERIGEDHFLPTLG
ETVSAYLKSHPVDWHDWEGGG
>Mature_580_residues
AKVGIVRLGSDIARYVPGIAWIRTYRIAWLPGDAIAGAALSAVLVPAGMAYAIASGLSAASGLYASIAALVAYAVFGPSR
VLVLGPDSALIALIAASVVPLAHGNAAHAAALAGALALLSGTLCLAVGLFRLGFVTDLLSMPIRYGYLNGIVVTIIVSQL
PKLLGLKVHEAAIPQQLRELATAVAAGKTNLAALSIGVLSLAVILAFKRWMPKMPGVLVAVVVATVAAAYFDLAARAGVG
VVGTLPRGLPVPEFPALAAKEWLALPASAAAIALVSLTDLSMLSQIYGLRSGQGVDRNRECVALGVANVAAGLFQGFAVA
ASGSRTPVAEDAGAKSQACGLIAALIVAALLLSVPQALRDTPQATLGAVVVAASLSLIEITGLRRLYRLRRPEFVQSLAC
FVGVVVWGVVTGVGIALGLAVLAFLWRAWRPYSAVLGRRDGVKGYHDIARHPDARRVPGLVLLRWDAPLFFANAEIFHER
VLTAAREAPTRTRWVAIAAEPVTDIDVTAADMLARLDDELHDADVQLCFAELKGPVKDSLKRYGLYERIGEDHFLPTLGE
TVSAYLKSHPVDWHDWEGGG

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=579, Percent_Identity=26.2521588946459, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI39752683, Length=579, Percent_Identity=26.2521588946459, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI94721259, Length=489, Percent_Identity=28.6298568507157, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI94721257, Length=489, Percent_Identity=28.6298568507157, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI94721255, Length=489, Percent_Identity=28.6298568507157, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI94721253, Length=489, Percent_Identity=28.6298568507157, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI269784651, Length=578, Percent_Identity=26.2975778546713, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI4557535, Length=510, Percent_Identity=27.0588235294118, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4505697, Length=501, Percent_Identity=26.9461077844311, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI45827802, Length=463, Percent_Identity=27.8617710583153, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI16418413, Length=517, Percent_Identity=25.1450676982592, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI217272867, Length=517, Percent_Identity=25.1450676982592, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI47131207, Length=510, Percent_Identity=27.843137254902, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI20336272, Length=510, Percent_Identity=27.843137254902, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI262206105, Length=560, Percent_Identity=26.4285714285714, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI262206075, Length=560, Percent_Identity=26.4285714285714, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI262206069, Length=560, Percent_Identity=26.4285714285714, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI262206063, Length=560, Percent_Identity=26.4285714285714, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI100913030, Length=509, Percent_Identity=24.1650294695481, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI20336282, Length=544, Percent_Identity=22.4264705882353, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI16306483, Length=543, Percent_Identity=22.0994475138122, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI16418457, Length=549, Percent_Identity=20.2185792349727, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI301601599, Length=549, Percent_Identity=20.2185792349727, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI65506789, Length=544, Percent_Identity=25.5514705882353, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI45827804, Length=270, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87081859, Length=566, Percent_Identity=24.2049469964664, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551690, Length=625, Percent_Identity=26.08, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17566848, Length=544, Percent_Identity=27.5735294117647, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI86564196, Length=623, Percent_Identity=23.916532905297, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI86565215, Length=579, Percent_Identity=23.6614853195164, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17562578, Length=631, Percent_Identity=23.9302694136292, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI86564876, Length=576, Percent_Identity=24.3055555555556, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193203292, Length=556, Percent_Identity=23.7410071942446, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI86565213, Length=268, Percent_Identity=27.9850746268657, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI86565209, Length=241, Percent_Identity=26.5560165975104, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI86565211, Length=241, Percent_Identity=26.5560165975104, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6325260, Length=562, Percent_Identity=19.7508896797153, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323121, Length=468, Percent_Identity=24.7863247863248, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319771, Length=480, Percent_Identity=24.1666666666667, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24666186, Length=538, Percent_Identity=24.3494423791822, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21358633, Length=539, Percent_Identity=24.4897959183673, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24649801, Length=560, Percent_Identity=24.2857142857143, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI19922482, Length=534, Percent_Identity=22.4719101123595, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24651449, Length=566, Percent_Identity=21.5547703180212, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI85815873, Length=542, Percent_Identity=22.8782287822878, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24663084, Length=557, Percent_Identity=24.4165170556553, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357695, Length=557, Percent_Identity=24.4165170556553, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21358229, Length=581, Percent_Identity=21.8588640275387, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647160, Length=158, Percent_Identity=28.4810126582279, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355087, Length=158, Percent_Identity=28.4810126582279, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60748; Mature: 60617

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVGIVRLGSDIARYVPGIAWIRTYRIAWLPGDAIAGAALSAVLVPAGMAYAIASGLSA
CCCCEEEECCHHHHHHCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGLYASIAALVAYAVFGPSRVLVLGPDSALIALIAASVVPLAHGNAAHAAALAGALALL
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SGTLCLAVGLFRLGFVTDLLSMPIRYGYLNGIVVTIIVSQLPKLLGLKVHEAAIPQQLRE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LATAVAAGKTNLAALSIGVLSLAVILAFKRWMPKMPGVLVAVVVATVAAAYFDLAARAGV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GVVGTLPRGLPVPEFPALAAKEWLALPASAAAIALVSLTDLSMLSQIYGLRSGQGVDRNR
CEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ECVALGVANVAAGLFQGFAVAASGSRTPVAEDAGAKSQACGLIAALIVAALLLSVPQALR
CEEEEHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTPQATLGAVVVAASLSLIEITGLRRLYRLRRPEFVQSLACFVGVVVWGVVTGVGIALGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLAFLWRAWRPYSAVLGRRDGVKGYHDIARHPDARRVPGLVLLRWDAPLFFANAEIFHE
HHHHHHHHCCCCHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCEEEHHHHHHHH
RVLTAAREAPTRTRWVAIAAEPVTDIDVTAADMLARLDDELHDADVQLCFAELKGPVKDS
HHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LKRYGLYERIGEDHFLPTLGETVSAYLKSHPVDWHDWEGGG
HHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKVGIVRLGSDIARYVPGIAWIRTYRIAWLPGDAIAGAALSAVLVPAGMAYAIASGLSA
CCCEEEECCHHHHHHCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGLYASIAALVAYAVFGPSRVLVLGPDSALIALIAASVVPLAHGNAAHAAALAGALALL
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SGTLCLAVGLFRLGFVTDLLSMPIRYGYLNGIVVTIIVSQLPKLLGLKVHEAAIPQQLRE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LATAVAAGKTNLAALSIGVLSLAVILAFKRWMPKMPGVLVAVVVATVAAAYFDLAARAGV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GVVGTLPRGLPVPEFPALAAKEWLALPASAAAIALVSLTDLSMLSQIYGLRSGQGVDRNR
CEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ECVALGVANVAAGLFQGFAVAASGSRTPVAEDAGAKSQACGLIAALIVAALLLSVPQALR
CEEEEHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTPQATLGAVVVAASLSLIEITGLRRLYRLRRPEFVQSLACFVGVVVWGVVTGVGIALGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLAFLWRAWRPYSAVLGRRDGVKGYHDIARHPDARRVPGLVLLRWDAPLFFANAEIFHE
HHHHHHHHCCCCHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCEEEHHHHHHHH
RVLTAAREAPTRTRWVAIAAEPVTDIDVTAADMLARLDDELHDADVQLCFAELKGPVKDS
HHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LKRYGLYERIGEDHFLPTLGETVSAYLKSHPVDWHDWEGGG
HHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]