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The map label for this gene is iorA [H]

Identifier: 161524865

GI number: 161524865

Start: 1864980

End: 1865420

Strand: Reverse

Name: iorA [H]

Synonym: Bmul_1692

Alternate gene names: 161524865

Gene position: 1865420-1864980 (Counterclockwise)

Preceding gene: 161524868

Following gene: 161524864

Centisome position: 54.09

GC content: 67.35

Gene sequence:

>441_bases
GTGAACATCGATTGCGACCCGTCCACGCCGTTGCTGTGGGTGCTGCGCGACCACTTGAACCTGACCGGGACGAAGTTCGG
CTGCGGCGTTGCAGCTTGCGGCGCGTGTACCGTGCATCTGGATGGTGCGGCGGTGCGATCTTGCGTCCTCCCGGTGGCAG
CGGTCGCGGGCAAGCGCATCACCACGATCGAAGGGCTGGCCGAATCGCCGGGCAAGCGCCATGCGTTGCAGCAGGCCTGG
ATCGACGAACAGGTACCGCAATGCGGCTATTGCCAGTCGGGCATGCTGATGGCGGCGGCAGACCTGTTGGCAAGGCAACC
GGACCCGACCGACGCCGATATCGACGCGGCCATCACCAACCTGTGTCGCTGTGGGACGTACCCGCGCGTGCGCACGGCCA
TCAAGCGTGCGGCGAAGGCGCTGCGGGAGGGCCGCGCGTGA

Upstream 100 bases:

>100_bases
ATTCAACCTTGGTTCAACCTTAAGGTGCCGATAGTCGGTTGGGCCATTGCGATACGAGGTAAGGAAGCAATACATGAATC
TTGACGTCAACCGCCAAGCG

Downstream 100 bases:

>100_bases
GCGTCGACGCGACGAATGTGCGGCGCGGCCGGCGCCGGTTTCTGCTAGGCGCGCTTGGCGTTGGCGGTGCGCTTGTGGTC
GGCTGGGGCGTGATGCCGCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MNIDCDPSTPLLWVLRDHLNLTGTKFGCGVAACGACTVHLDGAAVRSCVLPVAAVAGKRITTIEGLAESPGKRHALQQAW
IDEQVPQCGYCQSGMLMAAADLLARQPDPTDADIDAAITNLCRCGTYPRVRTAIKRAAKALREGRA

Sequences:

>Translated_146_residues
MNIDCDPSTPLLWVLRDHLNLTGTKFGCGVAACGACTVHLDGAAVRSCVLPVAAVAGKRITTIEGLAESPGKRHALQQAW
IDEQVPQCGYCQSGMLMAAADLLARQPDPTDADIDAAITNLCRCGTYPRVRTAIKRAAKALREGRA
>Mature_146_residues
MNIDCDPSTPLLWVLRDHLNLTGTKFGCGVAACGACTVHLDGAAVRSCVLPVAAVAGKRITTIEGLAESPGKRHALQQAW
IDEQVPQCGYCQSGMLMAAADLLARQPDPTDADIDAAITNLCRCGTYPRVRTAIKRAAKALREGRA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=34.6938775510204, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI71773480, Length=94, Percent_Identity=35.1063829787234, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786480, Length=156, Percent_Identity=35.8974358974359, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789232, Length=131, Percent_Identity=40.4580152671756, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=134, Percent_Identity=41.044776119403, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=142, Percent_Identity=37.3239436619718, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=142, Percent_Identity=37.3239436619718, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17737937, Length=151, Percent_Identity=33.112582781457, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647193, Length=136, Percent_Identity=33.0882352941176, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647195, Length=147, Percent_Identity=31.9727891156463, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647197, Length=147, Percent_Identity=31.9727891156463, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647199, Length=138, Percent_Identity=32.6086956521739, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15459; Mature: 15459

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDCDPSTPLLWVLRDHLNLTGTKFGCGVAACGACTVHLDGAAVRSCVLPVAAVAGKRI
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECHHHHHHHHHHHHHHCCCCH
TTIEGLAESPGKRHALQQAWIDEQVPQCGYCQSGMLMAAADLLARQPDPTDADIDAAITN
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
LCRCGTYPRVRTAIKRAAKALREGRA
HHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIDCDPSTPLLWVLRDHLNLTGTKFGCGVAACGACTVHLDGAAVRSCVLPVAAVAGKRI
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECHHHHHHHHHHHHHHCCCCH
TTIEGLAESPGKRHALQQAWIDEQVPQCGYCQSGMLMAAADLLARQPDPTDADIDAAITN
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
LCRCGTYPRVRTAIKRAAKALREGRA
HHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]