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The map label for this gene is lgrB [H]

Identifier: 161524770

GI number: 161524770

Start: 1752788

End: 1757764

Strand: Reverse

Name: lgrB [H]

Synonym: Bmul_1597

Alternate gene names: 161524770

Gene position: 1757764-1752788 (Counterclockwise)

Preceding gene: 161524771

Following gene: 161524769

Centisome position: 50.97

GC content: 73.24

Gene sequence:

>4977_bases
ATGACGAAGGTTCAACCCGACTGGCTCGCGCTCGCGACGCGGTTCGCGCAATTGCCGGACGCGCAGCGCGCGGTGTTCAT
CGACAAGCTCGGCGCGGCCGGCATCGATTTTCGCGTGCTGCCGATTCCGCCGCGCACGCCGCGCAGCGACCGCGTGCCGG
CGTCGTTCGCGCAGACGCGGTTGTGGCTGCACGCACGGCTGATCGATGCGCCGCAGGCGTATCACATCACCGAGCGGCTC
GCGCTGACGGGGCCGCTCGATCCGCACGCGCTGCGTGCGGCATGCGATGCGCTGATCGCACGTCACGAGGCGCTGCGCAC
GACGTTCGACGAAACGGCCGACGGCGTCGCACAGACGATTCATCCGCCATTGCGTTGCCCGTGGCGCGAAACCGATCTCG
AGGCGCTGCCGCCCGCGCAGCGCGACGCCCGTGCGCACGACGTCGCGGCGGCCGACGAAGCCGAACCGTTCGATCTCGGC
GCGGCACCGCTCGTGCGCGCGCATCTGCTGCGTTTCGATGCGACGCGGCACTGGCTCGCGCTGACCGTCCATCACATCGT
GTCCGACGGCTGGTCCTCCGGTGTGATGCTCGACGAACTCGCGGCGTTCTACCGCGCCTATGCGGACGACCGGCCGGTGT
CGCTCGCACCGCTGCCGATCCAGTATGCCGACTACGCGCTGTGGCAGCGCCGCTGGCTCGACGCCGGCGAGCGCGATCGT
CAGCTCGCGTTCTGGCGCGAACGGCTCGACGCGCAGCGCGGCGTACTGACATTGCCCGGCGCGCGCGCACGGCCGGCGCG
CCGCAGCGCGCTCGGCGCGCGGCATGCGTTCTCGCTCGACGCGCAGATCGGCGCGCAGCTGCGCGCGTTCGCGGCCGCGT
CGGGGGCGACGCCGTTCGCGGTGCTGCTCGCCGCACTCGACACGCTGCTCGCGCGCGCGACCGGCGAGGCGCGGATCTGC
GTCGGCGTGCCGGCCGCGAATCGCGAACGGGCGGAGACGGCCGGGCTGATCGGTTTTTTCGTCAACACGCTCGCGATCGA
CGTCGACGTGCCGGCCCATCGCGATTTCGCGTCGCTGGTCGCGCGCACGCAGCGCGCGCTCGTCGACGCGCAAATGCATC
AGGACGTGCCGTTCGAGCAGGTCGTCGACGCGCTCGGCGTGCCGCGCAGCGCGAGCCATCATCCGCTGTTCCAGGTGATG
GCCGCGTACGGCGAGCGCCGCGCGCTGCCGGCGTTCGGCGCCGCGTCGGCCGCGCTGCTGCCGTCCGGCACGCCGTCCGC
GAAATTCGACCTGACGCTCGCGATCGAAGCGACGCCGGACGGCTCGTTCGACGCGGCATTCGTCTATGCGCTGGACCTGT
TCGAGGCCGATGCGATCACGCGGCTCGCCGGCCGTTTCGTCACGCTGCTGCGCGATGCGCTCGCGCGGCCCGACACGCCG
GTCGGCGATCTCGACTGGCTGCCGACCGACGAGCGCGCGCAGCTTGCCGCGTGGAATGCGCCGGCCGGTGCGGCCGAGGC
CGAACCGTTCGTGCCCGTGCACGCGCGCATCGCCGCCCATGCACGGGCGCGGCCGCAGGCCCGCGGCGTCGCCGACATCG
ATCGTGCGCTGACGCGCGGTGAGGTCGACGCACGCGCCGCACGGCTCGCGCGCCACCTCGTCGCGGCCGGCGTGCGGCCC
GAAATGCGTGTCGGCGTCGCGCTGCAGCGCTCGGTCGATCTGCTCGTCGCGCTGATCGCGGTGCTGAAGTCGGGCGCCGC
GTTCGTGCCGCTCGATCCGGCGCATCCGCGCGAACGGCTTGCGCAGATCGTCGACGATGCGCGCATCGCGCACGTGCTGA
CCGACGGCGCGAGCGTCGCGTCGTTGCCCGAGGCGCCTGCGTTGCGCGTATGGCGCGCCGATCGCATCGACGCGCTCGAC
GAAGCGGCCGACGTCGCGCTGCCCGACGTGCTGCCCGGCCACGCGGCGTACGCGATCTACACGTCGGGGTCGACCGGCAA
GCCGAAGGGCGTGATCGTCGATCACGCGTCGTTCGCGCGCCATTGCGCGGCGATCGCCGAGCGCTACGGCGCCGGCGAGG
ACGACGTGTTCCTGCTGTTCCAGTCGGTCAACTTCGACGGCGCGCATGAAGGCTGGTTTTCGCAGTACATGTCGGGCGCG
GCGGTGTCGGTGACGGCCGACGTGCTGTGGCCGCCCGCGCAGACCTGCGCGATGATGAACCGCGACGGCGTGACGATGAC
CTACGTGCCGCCCGGCTGCGCGGCGCAGCTCGCCGAATGGGCGCTCGCGCACGGTGCGCCGCCCACACTGCGTTCGCTGA
CGGTCGGCGGCGAGGCGACCTCGCGCGAAGCATTCGCGATGCTGCGCCGCGCGCTGCCGAACGTGCGCGTCGTCAACGGC
TACGGGCCGACCGAGACGGTGATCACGCCGACGCTCTGGATGTTCCGTCCCGGCGACGATCTCGCGAAGCTCGGCGACGC
CGCCTATCTGCCGATCGGCACGCTGGTCGGCGCGCGCACCGCGCACGTGCTCGACGCGCGGCTGCATCCGCTGCCGGTCG
GCGTGATCGGCGAGCTCTATCTCGGCGGCGAAGGGATCGGCGTCGCGCGCGGCTATCTCGACCGGCCCGCGCTGACGGCC
GAGCGCTTCGTGCCCGATCCGTACGGCGCGCCGGGCGCGCGGCTGTATCGTACGGGCGACCTCGTGCGGCGCCGCGCGGA
CGGCGTGTTCGACTTCATCGGCCGCGTCGACCATCAGGTGAAGCTGCGCGGGCTGCGGATCGAACTCGGCGAGATCGAGG
CGCAGCTGGCCGCACACGACGCGGTCCGCGAAGCGTGCGCGGTCGTGCACGGGCAGGGCGCGCAGGCGCAGCTCGTCGCT
TACGTCGAACTGACGGCCGAGGCGCGCGCGGCTGCACAGCCCGTCGACGCCGCGACGCTCGACGCGCATCTGCGCCGCAC
GCTGCCCGATTACATGGTGCCCGCGCAGCTGATCGTGCTCGACACACTGCCGCGCAACGCGAACAGCAAGGTCGACCGCG
CGCGGCTGCCGGCGCCGGTGCGCGTCGAGCGTGCGTACGAAGCGCCGCACGACGGCGACGAAGCCGCGCTTGCGGCGATC
TGGCGCGACGTGCTCAACGTCGAACGCGTCGGCCGCGGCGATCATTTCTTCGAACTCGGCGGGCATTCGCTCGCGGCCGT
GCGCGTCGCGACGCGCGTGGCCGAACGGCTCGGCCGCGACGTGCCGGTGCGTGCGCTGTTCGAGGCGCCGCTGCTCGCGC
AATACGCACGGCAGGTCGCCGCCGCGCCGCGTGCCGCACACGCGGATGCCGCGGCTTCGCGCGTCGCGGTCGCGCAAGCC
GATGCGCACGGCGTATGGCCGCTGTCGCCAGCCCAGCTCGCGCTGTGGTTCCTCTGGCGCGCGCAGCCGGATAGCGCCGC
CTACAACATTCCGGTCGCGCTGCGCGTGCGCGGCCCGCTCGACGTCGACGCGCTGCGCGCGGCGTTGTCCGACGCGGCAG
CCGTTCATCCGGCGCTGCGTGTGCGCATCGTGCCGCGCGCGCACGCGCTGCCGGGGCAGCGAATCGTCGACGCGACGCCG
TTCGCGCTGCCGATCGTCGATCTGTCCGGGCACGACGACGCACATGCACGCGCGGTGGCGCTGACCGACGACGATGCGCT
CGCGCCGTTCGATCTCGCGGCCGATGCGCCGCTCTGGCGCGCGCGCGTGTTGCGGCTCGGCGCCGACGATCACGTGTTGT
CGATCGCGATTCATCACATCGTGTCCGACGGCGAATCGATCGAGCTGTGGCTCGACGCGGTGCGCACGCGCTACATCGCG
CACGTGCGCGGCAACGCTGCGCCGACCGGCGAGGCGGCACCGTTCGTGTTGCCGGCCCCGGCTGCAGCAGGGCGCGTCGA
CGACTGGCGCCACGCGCTCGCCGGCCTGCCGGCACGCATCCTGCCGCAGCGTGCGGACGCGCCGGCGGTTCCGCAATGGC
GCGCCGCGCGCCTCGCATTCGAATTCGATGGCGCGCTGATCCGCGCGGCGCGCGACGCGGCATCGGCCGCGCACGCGACG
CTGCCGATGCTGCTGCACGCGGCGCTGAACGCCGCGCTGTTCCGCGTGACGGGCGCGGGCGACCAGCCGGCCGGCGTGCT
CGCGTCGACGCGCGAGCTGACCGGCGACGCGGCGCGCGACGCGCTCGGGCTGTTCATCAATGCGGTGGTCGTGCGGACGC
GGCTTGATGCGACCGCGCGCCGCGCGGACGTGCTCGTGCAGGTGCGCGACACCGCGCTGGCCGCCTATGCGCGTGCCGAC
GTGCCGTTTGCCGACGTGGTCGCCGCGCTGCGCGCGCCGCGCGCGGCCGATGCGAATCCGCTGTTCCAGGTGATGTTCAA
CTATCTGCGCCCGACCGGTGCGGCCGCACGCGACTGGGCCGGGCTGTCGGTCGCTGCGTTCAACGACGTGCGGCATCGCG
TCGTGTTCACGCTCGAACTGGACGTCGTCGAGCATCCGGACGGGCGCGTCGGCGCGGCGTTCTCGTATGCCGACGAATTG
CTCGACGGCCGCTTCGTCGAGGCACTCGTCGCGCGCTATCACGACGAAGTCGCACGTTTCGCGCAGGCGGCCGACACGGT
ACTCGGCGCGCCCGACGCGCACGTCGCTGCGGCGCCCGTACGCGCCGCGAGAGGCGACGACGCCGATCCACGGGCGCGCG
CATCGCGCACGGCCGCCGCGCTCGCCGCGCTGTGGTTCGACACGTTCGCGACCGCCGCGCCGGCGCCCGACGCGGACCTG
TTCGAGGCGGGCGCGACGTCGTTCGACGTCGTGCGTTTCGTCGATGCCGCGTGCCGCGCGGGCCACGCGCTGACGATCGA
CGACGTGTTCGCCGTGCCGACGCTCGCCGCGCTCGGCGCGCGGCTCGACGCACGCGCGCACGCCGACGCATATCGGGAGG
CTCGCCATGCTGGCTGA

Upstream 100 bases:

>100_bases
CGCGGCGATCGACGAGGCCTGCGCGGCACGCGGCGCGACCGACGCGGCGAGCACGATCGACGCGCTGCTCGGCGAACTCG
AAACCCAATAAGGACGACGG

Downstream 100 bases:

>100_bases
AGTGCGCCCGGACGGATACACGGTGCCCGATACCTGCCGGCTGACGTTCGCGAACGACCTGTGCGCGGCACGCGACGGTG
CCGAGATTCGCGTCTCGCAC

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1658; Mature: 1657

Protein sequence:

>1658_residues
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPQAYHITERL
ALTGPLDPHALRAACDALIARHEALRTTFDETADGVAQTIHPPLRCPWRETDLEALPPAQRDARAHDVAAADEAEPFDLG
AAPLVRAHLLRFDATRHWLALTVHHIVSDGWSSGVMLDELAAFYRAYADDRPVSLAPLPIQYADYALWQRRWLDAGERDR
QLAFWRERLDAQRGVLTLPGARARPARRSALGARHAFSLDAQIGAQLRAFAAASGATPFAVLLAALDTLLARATGEARIC
VGVPAANRERAETAGLIGFFVNTLAIDVDVPAHRDFASLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVM
AAYGERRALPAFGAASAALLPSGTPSAKFDLTLAIEATPDGSFDAAFVYALDLFEADAITRLAGRFVTLLRDALARPDTP
VGDLDWLPTDERAQLAAWNAPAGAAEAEPFVPVHARIAAHARARPQARGVADIDRALTRGEVDARAARLARHLVAAGVRP
EMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVDDARIAHVLTDGASVASLPEAPALRVWRADRIDALD
EAADVALPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFARHCAAIAERYGAGEDDVFLLFQSVNFDGAHEGWFSQYMSGA
AVSVTADVLWPPAQTCAMMNRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNG
YGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGARTAHVLDARLHPLPVGVIGELYLGGEGIGVARGYLDRPALTA
ERFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGAQAQLVA
YVELTAEARAAAQPVDAATLDAHLRRTLPDYMVPAQLIVLDTLPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAI
WRDVLNVERVGRGDHFFELGGHSLAAVRVATRVAERLGRDVPVRALFEAPLLAQYARQVAAAPRAAHADAAASRVAVAQA
DAHGVWPLSPAQLALWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAALSDAAAVHPALRVRIVPRAHALPGQRIVDATP
FALPIVDLSGHDDAHARAVALTDDDALAPFDLAADAPLWRARVLRLGADDHVLSIAIHHIVSDGESIELWLDAVRTRYIA
HVRGNAAPTGEAAPFVLPAPAAAGRVDDWRHALAGLPARILPQRADAPAVPQWRAARLAFEFDGALIRAARDAASAAHAT
LPMLLHAALNAALFRVTGAGDQPAGVLASTRELTGDAARDALGLFINAVVVRTRLDATARRADVLVQVRDTALAAYARAD
VPFADVVAALRAPRAADANPLFQVMFNYLRPTGAAARDWAGLSVAAFNDVRHRVVFTLELDVVEHPDGRVGAAFSYADEL
LDGRFVEALVARYHDEVARFAQAADTVLGAPDAHVAAAPVRAARGDDADPRARASRTAAALAALWFDTFATAAPAPDADL
FEAGATSFDVVRFVDAACRAGHALTIDDVFAVPTLAALGARLDARAHADAYREARHAG

Sequences:

>Translated_1658_residues
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPQAYHITERL
ALTGPLDPHALRAACDALIARHEALRTTFDETADGVAQTIHPPLRCPWRETDLEALPPAQRDARAHDVAAADEAEPFDLG
AAPLVRAHLLRFDATRHWLALTVHHIVSDGWSSGVMLDELAAFYRAYADDRPVSLAPLPIQYADYALWQRRWLDAGERDR
QLAFWRERLDAQRGVLTLPGARARPARRSALGARHAFSLDAQIGAQLRAFAAASGATPFAVLLAALDTLLARATGEARIC
VGVPAANRERAETAGLIGFFVNTLAIDVDVPAHRDFASLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVM
AAYGERRALPAFGAASAALLPSGTPSAKFDLTLAIEATPDGSFDAAFVYALDLFEADAITRLAGRFVTLLRDALARPDTP
VGDLDWLPTDERAQLAAWNAPAGAAEAEPFVPVHARIAAHARARPQARGVADIDRALTRGEVDARAARLARHLVAAGVRP
EMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVDDARIAHVLTDGASVASLPEAPALRVWRADRIDALD
EAADVALPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFARHCAAIAERYGAGEDDVFLLFQSVNFDGAHEGWFSQYMSGA
AVSVTADVLWPPAQTCAMMNRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNG
YGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGARTAHVLDARLHPLPVGVIGELYLGGEGIGVARGYLDRPALTA
ERFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGAQAQLVA
YVELTAEARAAAQPVDAATLDAHLRRTLPDYMVPAQLIVLDTLPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAI
WRDVLNVERVGRGDHFFELGGHSLAAVRVATRVAERLGRDVPVRALFEAPLLAQYARQVAAAPRAAHADAAASRVAVAQA
DAHGVWPLSPAQLALWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAALSDAAAVHPALRVRIVPRAHALPGQRIVDATP
FALPIVDLSGHDDAHARAVALTDDDALAPFDLAADAPLWRARVLRLGADDHVLSIAIHHIVSDGESIELWLDAVRTRYIA
HVRGNAAPTGEAAPFVLPAPAAAGRVDDWRHALAGLPARILPQRADAPAVPQWRAARLAFEFDGALIRAARDAASAAHAT
LPMLLHAALNAALFRVTGAGDQPAGVLASTRELTGDAARDALGLFINAVVVRTRLDATARRADVLVQVRDTALAAYARAD
VPFADVVAALRAPRAADANPLFQVMFNYLRPTGAAARDWAGLSVAAFNDVRHRVVFTLELDVVEHPDGRVGAAFSYADEL
LDGRFVEALVARYHDEVARFAQAADTVLGAPDAHVAAAPVRAARGDDADPRARASRTAAALAALWFDTFATAAPAPDADL
FEAGATSFDVVRFVDAACRAGHALTIDDVFAVPTLAALGARLDARAHADAYREARHAG
>Mature_1657_residues
TKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPQAYHITERLA
LTGPLDPHALRAACDALIARHEALRTTFDETADGVAQTIHPPLRCPWRETDLEALPPAQRDARAHDVAAADEAEPFDLGA
APLVRAHLLRFDATRHWLALTVHHIVSDGWSSGVMLDELAAFYRAYADDRPVSLAPLPIQYADYALWQRRWLDAGERDRQ
LAFWRERLDAQRGVLTLPGARARPARRSALGARHAFSLDAQIGAQLRAFAAASGATPFAVLLAALDTLLARATGEARICV
GVPAANRERAETAGLIGFFVNTLAIDVDVPAHRDFASLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMA
AYGERRALPAFGAASAALLPSGTPSAKFDLTLAIEATPDGSFDAAFVYALDLFEADAITRLAGRFVTLLRDALARPDTPV
GDLDWLPTDERAQLAAWNAPAGAAEAEPFVPVHARIAAHARARPQARGVADIDRALTRGEVDARAARLARHLVAAGVRPE
MRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVDDARIAHVLTDGASVASLPEAPALRVWRADRIDALDE
AADVALPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFARHCAAIAERYGAGEDDVFLLFQSVNFDGAHEGWFSQYMSGAA
VSVTADVLWPPAQTCAMMNRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNGY
GPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGARTAHVLDARLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAE
RFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGAQAQLVAY
VELTAEARAAAQPVDAATLDAHLRRTLPDYMVPAQLIVLDTLPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAIW
RDVLNVERVGRGDHFFELGGHSLAAVRVATRVAERLGRDVPVRALFEAPLLAQYARQVAAAPRAAHADAAASRVAVAQAD
AHGVWPLSPAQLALWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAALSDAAAVHPALRVRIVPRAHALPGQRIVDATPF
ALPIVDLSGHDDAHARAVALTDDDALAPFDLAADAPLWRARVLRLGADDHVLSIAIHHIVSDGESIELWLDAVRTRYIAH
VRGNAAPTGEAAPFVLPAPAAAGRVDDWRHALAGLPARILPQRADAPAVPQWRAARLAFEFDGALIRAARDAASAAHATL
PMLLHAALNAALFRVTGAGDQPAGVLASTRELTGDAARDALGLFINAVVVRTRLDATARRADVLVQVRDTALAAYARADV
PFADVVAALRAPRAADANPLFQVMFNYLRPTGAAARDWAGLSVAAFNDVRHRVVFTLELDVVEHPDGRVGAAFSYADELL
DGRFVEALVARYHDEVARFAQAADTVLGAPDAHVAAAPVRAARGDDADPRARASRTAAALAALWFDTFATAAPAPDADLF
EAGATSFDVVRFVDAACRAGHALTIDDVFAVPTLAALGARLDARAHADAYREARHAG

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=612, Percent_Identity=22.8758169934641, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI42544132, Length=368, Percent_Identity=22.2826086956522, Blast_Score=75, Evalue=7e-13,
Organism=Homo sapiens, GI28416953, Length=588, Percent_Identity=23.9795918367347, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI58082049, Length=496, Percent_Identity=22.9838709677419, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI157311624, Length=498, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI157311622, Length=498, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1786801, Length=1053, Percent_Identity=29.8195631528965, Blast_Score=312, Evalue=1e-85,
Organism=Escherichia coli, GI1790505, Length=432, Percent_Identity=26.1574074074074, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI145693145, Length=524, Percent_Identity=24.236641221374, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786810, Length=526, Percent_Identity=25.6653992395437, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI221142682, Length=514, Percent_Identity=22.568093385214, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17556356, Length=962, Percent_Identity=21.9334719334719, Blast_Score=131, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=1064, Percent_Identity=20.0187969924812, Blast_Score=127, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32563687, Length=510, Percent_Identity=23.921568627451, Blast_Score=92, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319591, Length=758, Percent_Identity=25.5936675461741, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24648676, Length=625, Percent_Identity=27.36, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24581924, Length=370, Percent_Identity=26.2162162162162, Blast_Score=80, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 177289; Mature: 177158

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTR
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LWLHARLIDAPQAYHITERLALTGPLDPHALRAACDALIARHEALRTTFDETADGVAQTI
HHHHHHHHCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPPLRCPWRETDLEALPPAQRDARAHDVAAADEAEPFDLGAAPLVRAHLLRFDATRHWLA
CCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
LTVHHIVSDGWSSGVMLDELAAFYRAYADDRPVSLAPLPIQYADYALWQRRWLDAGERDR
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCH
QLAFWRERLDAQRGVLTLPGARARPARRSALGARHAFSLDAQIGAQLRAFAAASGATPFA
HHHHHHHHHHHHCCEEECCCCCCCCHHHHHHCCHHHEECCHHHHHHHHHHHHCCCCCHHH
VLLAALDTLLARATGEARICVGVPAANRERAETAGLIGFFVNTLAIDVDVPAHRDFASLV
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHH
ARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMAAYGERRALPAFGAASAALL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHCC
PSGTPSAKFDLTLAIEATPDGSFDAAFVYALDLFEADAITRLAGRFVTLLRDALARPDTP
CCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGDLDWLPTDERAQLAAWNAPAGAAEAEPFVPVHARIAAHARARPQARGVADIDRALTRG
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCC
EVDARAARLARHLVAAGVRPEMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHH
AQIVDDARIAHVLTDGASVASLPEAPALRVWRADRIDALDEAADVALPDVLPGHAAYAIY
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEEE
TSGSTGKPKGVIVDHASFARHCAAIAERYGAGEDDVFLLFQSVNFDGAHEGWFSQYMSGA
ECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
AVSVTADVLWPPAQTCAMMNRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEAT
EEEEEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCC
SREAFAMLRRALPNVRVVNGYGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGART
HHHHHHHHHHHCCCCEEEECCCCCCCEECCEEEEECCCHHHHHHCCCCCCCHHHHHHCHH
AHVLDARLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAERFVPDPYGAPGARLYRTGD
HHHHHCCCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCEEEHHHH
LVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGAQAQLVA
HHHHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
YVELTAEARAAAQPVDAATLDAHLRRTLPDYMVPAQLIVLDTLPRNANSKVDRARLPAPV
EEEEHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCHHHCCCCCE
RVERAYEAPHDGDEAALAAIWRDVLNVERVGRGDHFFELGGHSLAAVRVATRVAERLGRD
EEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
VPVRALFEAPLLAQYARQVAAAPRAAHADAAASRVAVAQADAHGVWPLSPAQLALWFLWR
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHEE
AQPDSAAYNIPVALRVRGPLDVDALRAALSDAAAVHPALRVRIVPRAHALPGQRIVDATP
CCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCC
FALPIVDLSGHDDAHARAVALTDDDALAPFDLAADAPLWRARVLRLGADDHVLSIAIHHI
CEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
VSDGESIELWLDAVRTRYIAHVRGNAAPTGEAAPFVLPAPAAAGRVDDWRHALAGLPARI
HCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCHHH
LPQRADAPAVPQWRAARLAFEFDGALIRAARDAASAAHATLPMLLHAALNAALFRVTGAG
CCCCCCCCCCCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
DQPAGVLASTRELTGDAARDALGLFINAVVVRTRLDATARRADVLVQVRDTALAAYARAD
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHCC
VPFADVVAALRAPRAADANPLFQVMFNYLRPTGAAARDWAGLSVAAFNDVRHRVVFTLEL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHCCCEEEEEEEEE
DVVEHPDGRVGAAFSYADELLDGRFVEALVARYHDEVARFAQAADTVLGAPDAHVAAAPV
EEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCH
RAARGDDADPRARASRTAAALAALWFDTFATAAPAPDADLFEAGATSFDVVRFVDAACRA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHC
GHALTIDDVFAVPTLAALGARLDARAHADAYREARHAG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LWLHARLIDAPQAYHITERLALTGPLDPHALRAACDALIARHEALRTTFDETADGVAQTI
HHHHHHHHCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPPLRCPWRETDLEALPPAQRDARAHDVAAADEAEPFDLGAAPLVRAHLLRFDATRHWLA
CCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
LTVHHIVSDGWSSGVMLDELAAFYRAYADDRPVSLAPLPIQYADYALWQRRWLDAGERDR
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCH
QLAFWRERLDAQRGVLTLPGARARPARRSALGARHAFSLDAQIGAQLRAFAAASGATPFA
HHHHHHHHHHHHCCEEECCCCCCCCHHHHHHCCHHHEECCHHHHHHHHHHHHCCCCCHHH
VLLAALDTLLARATGEARICVGVPAANRERAETAGLIGFFVNTLAIDVDVPAHRDFASLV
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHH
ARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMAAYGERRALPAFGAASAALL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHCC
PSGTPSAKFDLTLAIEATPDGSFDAAFVYALDLFEADAITRLAGRFVTLLRDALARPDTP
CCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGDLDWLPTDERAQLAAWNAPAGAAEAEPFVPVHARIAAHARARPQARGVADIDRALTRG
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCC
EVDARAARLARHLVAAGVRPEMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHH
AQIVDDARIAHVLTDGASVASLPEAPALRVWRADRIDALDEAADVALPDVLPGHAAYAIY
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEEE
TSGSTGKPKGVIVDHASFARHCAAIAERYGAGEDDVFLLFQSVNFDGAHEGWFSQYMSGA
ECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
AVSVTADVLWPPAQTCAMMNRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEAT
EEEEEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCC
SREAFAMLRRALPNVRVVNGYGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGART
HHHHHHHHHHHCCCCEEEECCCCCCCEECCEEEEECCCHHHHHHCCCCCCCHHHHHHCHH
AHVLDARLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAERFVPDPYGAPGARLYRTGD
HHHHHCCCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCEEEHHHH
LVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGAQAQLVA
HHHHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
YVELTAEARAAAQPVDAATLDAHLRRTLPDYMVPAQLIVLDTLPRNANSKVDRARLPAPV
EEEEHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCHHHCCCCCE
RVERAYEAPHDGDEAALAAIWRDVLNVERVGRGDHFFELGGHSLAAVRVATRVAERLGRD
EEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
VPVRALFEAPLLAQYARQVAAAPRAAHADAAASRVAVAQADAHGVWPLSPAQLALWFLWR
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHEE
AQPDSAAYNIPVALRVRGPLDVDALRAALSDAAAVHPALRVRIVPRAHALPGQRIVDATP
CCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCC
FALPIVDLSGHDDAHARAVALTDDDALAPFDLAADAPLWRARVLRLGADDHVLSIAIHHI
CEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
VSDGESIELWLDAVRTRYIAHVRGNAAPTGEAAPFVLPAPAAAGRVDDWRHALAGLPARI
HCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCHHH
LPQRADAPAVPQWRAARLAFEFDGALIRAARDAASAAHATLPMLLHAALNAALFRVTGAG
CCCCCCCCCCCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
DQPAGVLASTRELTGDAARDALGLFINAVVVRTRLDATARRADVLVQVRDTALAAYARAD
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHCC
VPFADVVAALRAPRAADANPLFQVMFNYLRPTGAAARDWAGLSVAAFNDVRHRVVFTLEL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHCCCEEEEEEEEE
DVVEHPDGRVGAAFSYADELLDGRFVEALVARYHDEVARFAQAADTVLGAPDAHVAAAPV
EEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCH
RAARGDDADPRARASRTAAALAALWFDTFATAAPAPDADLFEAGATSFDVVRFVDAACRA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHC
GHALTIDDVFAVPTLAALGARLDARAHADAYREARHAG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA