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The map label for this gene is arnA [H]

Identifier: 161524584

GI number: 161524584

Start: 1553502

End: 1554557

Strand: Reverse

Name: arnA [H]

Synonym: Bmul_1411

Alternate gene names: 161524584

Gene position: 1554557-1553502 (Counterclockwise)

Preceding gene: 161524585

Following gene: 161524583

Centisome position: 45.08

GC content: 61.46

Gene sequence:

>1056_bases
ATGAAAGCAAAAAAAGTCCTGATCCTGGGTGTGAACGGCTTCATCGGCCACCACCTGTCGAAGCGCATTCTTGAAACCAC
CGATTGGGAAGTGTTCGGCATGGACATGCAGACCGATCGGCTCGGCGATCTCGTCAAGCACGAGCGGATGCATTTCTTCG
AAGGCGACATCACGATCAACAAGGAGTGGGTCGAGTATCACGTGAAGAAGTGCGACGTGATCCTGCCGCTCGTCGCGATC
GCGACGCCCGCGACCTACGTCCAGCAGCCGCTGCGCGTGTTCGAACTCGACTTCGAGGCGAACCTGCCGATCGTGCGTTC
GGCCGTCAAGTACGGCAAGCACCTCGTGTTCCCGTCGACGTCGGAAGTCTACGGCATGTGCTCGGACGAGCAGTTCGACC
CGGACGCGTCCGCCCTCACCTACGGCCCGATCAACAAGCCGCGCTGGATCTACGCCTGCTCGAAGCAGCTGATGGATCGC
GTGATCTGGGGCTACGGGATGGAAGGCCTGAACTTCACGCTGTTCCGTCCGTTCAACTGGATCGGCCCGGGCCTCGACTC
GATCTACACGCCGAAGGAAGGCAGCTCGCGCGTCGTTACGCAGTTCCTCGGCCACATCGTGCGCGGCGAGAACATCAGCC
TCGTCGACGGCGGCTCGCAGAAGCGCGCGTTCACCGACATCGACGACGGCATCAGCGCGCTGATGAAGATCATCGAGAAT
CCGAACGGCATCGCCTCGGGCAAGATCTACAACATCGGGAATCCGAACAACAACTTCTCGGTGCGCGAACTCGCGAACAA
GATGCTCGAGCTCGCCGCCGAATTCCCCGAGTATGCGGATTCGGCCAAGCAGGTGCGGCTCGTCGAGACCACCTCGGGCG
CGTACTACGGCAACGGCTATCAGGACGTGCAGAACCGCGTGCCGAAGATCGACAACACGATGCAGGAGCTCGGCTGGGCG
CCGCAATCGACGTTCGACGACGCGCTGCGCAAGATCTTCGAAGCGTATCGCGGCCATGTCGCCGACGCGCGCGCACTCGT
CGAGCAACAAGGCTGA

Upstream 100 bases:

>100_bases
GCGCGCTATCCATTCTCGAACTGCGGCAACAGCGCGACGGCCGCGAAACCGTCGTGACGCCCGCGGAATTCGCGCAGTTC
ATTCATTCTTCCCGTCATTC

Downstream 100 bases:

>100_bases
CGGGACGCTCGCTTGGCTCGCATCGTTCTCAAGATCGACGTCGACACGCTGCGCGGCACGCGTGAAGGCGTGCCGAATCT
CGCGCGCATCTTCGACCGCT

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAI
ATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDR
VIWGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTDIDDGISALMKIIEN
PNGIASGKIYNIGNPNNNFSVRELANKMLELAAEFPEYADSAKQVRLVETTSGAYYGNGYQDVQNRVPKIDNTMQELGWA
PQSTFDDALRKIFEAYRGHVADARALVEQQG

Sequences:

>Translated_351_residues
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAI
ATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDR
VIWGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTDIDDGISALMKIIEN
PNGIASGKIYNIGNPNNNFSVRELANKMLELAAEFPEYADSAKQVRLVETTSGAYYGNGYQDVQNRVPKIDNTMQELGWA
PQSTFDDALRKIFEAYRGHVADARALVEQQG
>Mature_351_residues
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAI
ATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDR
VIWGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTDIDDGISALMKIIEN
PNGIASGKIYNIGNPNNNFSVRELANKMLELAAEFPEYADSAKQVRLVETTSGAYYGNGYQDVQNRVPKIDNTMQELGWA
PQSTFDDALRKIFEAYRGHVADARALVEQQG

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=341, Percent_Identity=25.8064516129032, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI7657641, Length=349, Percent_Identity=23.4957020057307, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788589, Length=339, Percent_Identity=55.7522123893805, Blast_Score=384, Evalue=1e-108,
Organism=Drosophila melanogaster, GI21356223, Length=349, Percent_Identity=24.3553008595989, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 39527; Mature: 39527

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITIN
CCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCEEEC
KEWVEYHVKKCDVILPLVAIATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPST
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCC
SEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNW
HHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
IGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTDIDDGISALMKIIEN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCC
PNGIASGKIYNIGNPNNNFSVRELANKMLELAAEFPEYADSAKQVRLVETTSGAYYGNGY
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHCCCHHEEEEEEECCCCCCCCCH
QDVQNRVPKIDNTMQELGWAPQSTFDDALRKIFEAYRGHVADARALVEQQG
HHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITIN
CCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCEEEC
KEWVEYHVKKCDVILPLVAIATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPST
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCC
SEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNW
HHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
IGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTDIDDGISALMKIIEN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCC
PNGIASGKIYNIGNPNNNFSVRELANKMLELAAEFPEYADSAKQVRLVETTSGAYYGNGY
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHCCCHHEEEEEEECCCCCCCCCH
QDVQNRVPKIDNTMQELGWAPQSTFDDALRKIFEAYRGHVADARALVEQQG
HHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA