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The map label for this gene is yedX [C]

Identifier: 161524485

GI number: 161524485

Start: 1441236

End: 1441856

Strand: Reverse

Name: yedX [C]

Synonym: Bmul_1312

Alternate gene names: 161524485

Gene position: 1441856-1441236 (Counterclockwise)

Preceding gene: 161524487

Following gene: 161524484

Centisome position: 41.81

GC content: 66.18

Gene sequence:

>621_bases
ATGGTACGCCGCGCAGCGGCCCCGCGCAGGGCCGCGCCCCCGTGCCGCAGGCCGCGCCGGCAAGGCGTCGACAGCCGGTC
ATGCGCGGCGCATTATCTTTGCTATCGCGCGCGTATTTGCCGCAGGAACCTTCTTACAATGCCTGCACGGCGCTCGCTTC
AACTTCGCCGACGGGTATGTAGCCACGTGACGTGGAGCCTCGATCCGCCGCACTGTCATTGGATCGAGCCGCCGCCGAAC
ATCGCATTCACACAAGGACAATTGCGAATGGGAAAGCTCACTACCCACGTACTCGATACGGCGAACGGTCGTCCGGGCGC
CGCACTCAAGGTGGACCTCTACGCGCTGGACGGCGACTCGCGCCGCGCGATCAAGACCGTGCTGACCAATAGCGACGGCC
GCTGCGACGAACCGCTGCTCGAAGGCGCCGCGCTGACCGCCGGCGAATACGAACTCGTGTTCCATGCCGGCGACTACTTC
GCGTCGCTCGGCGTGAAGGTGCCCGAACCCCGTTTCGTCGACCGCGTCGTGCTGCGTTTCGGCATCGCCGATCCGGGCGC
GCACTATCACGTGCCGCTGCTCGTGTCGCCGTGGTCGTACAGCACCTATCGCGGCAGCTGA

Upstream 100 bases:

>100_bases
TGCGGCGCCGGCCGTCGGCCGACGCGCACGGCGGGAGGATCGCCGATGCGCGCGCCGCGCACAATGCGCGATCACGAATA
CCGGGCTTCACGGTCGCGAT

Downstream 100 bases:

>100_bases
CACACGCATCGGCTGCCCGCATCAAGACAACGATCTGAGTCTGGAGGAGTTTCATGGAAGGCTTCATCACCGACTGGCTG
AACCTCGCGCTGCGATGGCT

Product: hydroxyisourate hydrolase

Products: NA

Alternate protein names: HIU hydrolase 2; HIUHase 2 [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MVRRAAAPRRAAPPCRRPRRQGVDSRSCAAHYLCYRARICRRNLLTMPARRSLQLRRRVCSHVTWSLDPPHCHWIEPPPN
IAFTQGQLRMGKLTTHVLDTANGRPGAALKVDLYALDGDSRRAIKTVLTNSDGRCDEPLLEGAALTAGEYELVFHAGDYF
ASLGVKVPEPRFVDRVVLRFGIADPGAHYHVPLLVSPWSYSTYRGS

Sequences:

>Translated_206_residues
MVRRAAAPRRAAPPCRRPRRQGVDSRSCAAHYLCYRARICRRNLLTMPARRSLQLRRRVCSHVTWSLDPPHCHWIEPPPN
IAFTQGQLRMGKLTTHVLDTANGRPGAALKVDLYALDGDSRRAIKTVLTNSDGRCDEPLLEGAALTAGEYELVFHAGDYF
ASLGVKVPEPRFVDRVVLRFGIADPGAHYHVPLLVSPWSYSTYRGS
>Mature_206_residues
MVRRAAAPRRAAPPCRRPRRQGVDSRSCAAHYLCYRARICRRNLLTMPARRSLQLRRRVCSHVTWSLDPPHCHWIEPPPN
IAFTQGQLRMGKLTTHVLDTANGRPGAALKVDLYALDGDSRRAIKTVLTNSDGRCDEPLLEGAALTAGEYELVFHAGDYF
ASLGVKVPEPRFVDRVVLRFGIADPGAHYHVPLLVSPWSYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=114, Percent_Identity=36.8421052631579, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115532922, Length=126, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115532920, Length=126, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534555, Length=115, Percent_Identity=33.9130434782609, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652571, Length=116, Percent_Identity=37.9310344827586, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 23069; Mature: 23069

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00768 TRANSTHYRETIN_1 ; PS00769 TRANSTHYRETIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRAAAPRRAAPPCRRPRRQGVDSRSCAAHYLCYRARICRRNLLTMPARRSLQLRRRVC
CCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SHVTWSLDPPHCHWIEPPPNIAFTQGQLRMGKLTTHVLDTANGRPGAALKVDLYALDGDS
HHCEECCCCCCCEECCCCCCEEEECCCEEHHHHHHHHHHCCCCCCCCEEEEEEEEECCCC
RRAIKTVLTNSDGRCDEPLLEGAALTAGEYELVFHAGDYFASLGVKVPEPRFVDRVVLRF
HHHHHHHHCCCCCCCCCHHHCCCEECCCCEEEEEECCCHHHHCCCCCCCCHHHHHHHHHH
GIADPGAHYHVPLLVSPWSYSTYRGS
CCCCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MVRRAAAPRRAAPPCRRPRRQGVDSRSCAAHYLCYRARICRRNLLTMPARRSLQLRRRVC
CCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SHVTWSLDPPHCHWIEPPPNIAFTQGQLRMGKLTTHVLDTANGRPGAALKVDLYALDGDS
HHCEECCCCCCCEECCCCCCEEEECCCEEHHHHHHHHHHCCCCCCCCEEEEEEEEECCCC
RRAIKTVLTNSDGRCDEPLLEGAALTAGEYELVFHAGDYFASLGVKVPEPRFVDRVVLRF
HHHHHHHHCCCCCCCCCHHHCCCEECCCCEEEEEECCCHHHHCCCCCCCCHHHHHHHHHH
GIADPGAHYHVPLLVSPWSYSTYRGS
CCCCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]