Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 161524429

GI number: 161524429

Start: 1385468

End: 1386283

Strand: Reverse

Name: map [H]

Synonym: Bmul_1256

Alternate gene names: 161524429

Gene position: 1386283-1385468 (Counterclockwise)

Preceding gene: 161524446

Following gene: 161524428

Centisome position: 40.2

GC content: 64.58

Gene sequence:

>816_bases
ATGGCTATTACGCTCAAAAACGAACACGACATCGCCCAGATGCGCATCGCCTGCCGTCTGGCGAGCGAAGTGCTCGATTT
CATCACGCCGCACGTCGTCGCAGGGATCACGACCGCCGAACTCGACCGCCTCTGCCACGAATACATGGTCAACGAGCAAG
GCACGATCCCCGCGCCGCTGAACTATCAGCCGCCCGGCTATCCGCCGTACCCGAAGGCCACCTGCATCTCGGTCAACGAC
GTGATCTGCCACGGCATTCCCGGCGAGAAGGTGCTCAAGAACGGCGACGCGCTGAACATCGACATCACCGTGATCAAGAA
CGGCTATTTCGGCGACACGAGCCGGATGTTCATCGTCGGCGAGGGTTCGATCCTCGCGAAGCGCCTCGTGCAGACCACCT
ACGAGTGCATGTGGCTCGGCATCGACCAGGTCAAGCCCGGCGCGCATCTCGGCGACATTGGCCATGCGATCCAGAAGCAT
GCGGAAGCGCAGGGCTACAGCGTCGTGCGCGAATACTGCGGGCACGGCATCGGCACGGTGTTCCACGAGGAGCCGCAGGT
CGTCCATTACGGCCGGCCGGGCACCGGCATCGAGCTGAAGCCGGGGATGATCTTCACGATCGAGCCGATGATCAACGCCG
GCAAGCGCGACATCCGCACGATGCCCGACCAGTGGACGGTCAAGACGCGCGATCGCAGCCTCTCCGCGCAGTGGGAGCAC
ACGGTGCTCGTCACCGAAACCGGCTACGAAGTGCTGACCGTGTCGGCCGGCACGCCCGCGCGGCCTGTGTTCGCGCAGCC
GGCCGCCGCGGTCTGA

Upstream 100 bases:

>100_bases
ACAATCGGCGAAAACCCGCATCGGCGCGGCCGCAAGGGGCTGCGACGGCCGCCATAAGGTGCGATAATCCGTCAATTCAC
CGCATTCCAGGCTCACCTCG

Downstream 100 bases:

>100_bases
GCGCCGCGTCCCGCGCCCCCGCCCCACCCTCGTCCGAACGGCCGCTCATGAGCGCTCACGCCGCCCCCGCCCCCGAAGCG
CTGTCGCAGCGCGCCGCATT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAITLKNEHDIAQMRIACRLASEVLDFITPHVVAGITTAELDRLCHEYMVNEQGTIPAPLNYQPPGYPPYPKATCISVND
VICHGIPGEKVLKNGDALNIDITVIKNGYFGDTSRMFIVGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKH
AEAQGYSVVREYCGHGIGTVFHEEPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TVLVTETGYEVLTVSAGTPARPVFAQPAAAV

Sequences:

>Translated_271_residues
MAITLKNEHDIAQMRIACRLASEVLDFITPHVVAGITTAELDRLCHEYMVNEQGTIPAPLNYQPPGYPPYPKATCISVND
VICHGIPGEKVLKNGDALNIDITVIKNGYFGDTSRMFIVGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKH
AEAQGYSVVREYCGHGIGTVFHEEPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TVLVTETGYEVLTVSAGTPARPVFAQPAAAV
>Mature_270_residues
AITLKNEHDIAQMRIACRLASEVLDFITPHVVAGITTAELDRLCHEYMVNEQGTIPAPLNYQPPGYPPYPKATCISVNDV
ICHGIPGEKVLKNGDALNIDITVIKNGYFGDTSRMFIVGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKHA
EAQGYSVVREYCGHGIGTVFHEEPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEHT
VLVTETGYEVLTVSAGTPARPVFAQPAAAV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=262, Percent_Identity=49.236641221374, Blast_Score=245, Evalue=3e-65,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=39.2857142857143, Blast_Score=188, Evalue=4e-48,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=59.6078431372549, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1788728, Length=254, Percent_Identity=24.8031496062992, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=46.031746031746, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=46.2450592885375, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI21355531, Length=262, Percent_Identity=46.5648854961832, Blast_Score=225, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=38.1526104417671, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29702; Mature: 29571

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITLKNEHDIAQMRIACRLASEVLDFITPHVVAGITTAELDRLCHEYMVNEQGTIPAPL
CEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
NYQPPGYPPYPKATCISVNDVICHGIPGEKVLKNGDALNIDITVIKNGYFGDTSRMFIVG
CCCCCCCCCCCCEEEEEECCEEEECCCCHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCE
FHEEPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
ECCCCCEEEECCCCCCEEECCCEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TVLVTETGYEVLTVSAGTPARPVFAQPAAAV
EEEEEECCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AITLKNEHDIAQMRIACRLASEVLDFITPHVVAGITTAELDRLCHEYMVNEQGTIPAPL
EEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
NYQPPGYPPYPKATCISVNDVICHGIPGEKVLKNGDALNIDITVIKNGYFGDTSRMFIVG
CCCCCCCCCCCCEEEEEECCEEEECCCCHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCE
FHEEPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
ECCCCCEEEECCCCCCEEECCCEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TVLVTETGYEVLTVSAGTPARPVFAQPAAAV
EEEEEECCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]