Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 161524242

GI number: 161524242

Start: 1165203

End: 1166402

Strand: Reverse

Name: aspC [H]

Synonym: Bmul_1066

Alternate gene names: 161524242

Gene position: 1166402-1165203 (Counterclockwise)

Preceding gene: 161524248

Following gene: 161524240

Centisome position: 33.82

GC content: 66.0

Gene sequence:

>1200_bases
ATGTCGCTCTTCTCCGCTGTCCAGCTTGCTCCCCGCGACCCGATCCTGGGCCTGAACGAAGCCTTCAACGCCGATACGCG
TCCGACCAAGGTCAATCTCGGCGTCGGCGTCTACACGAACGAAGACGGCAAGATTCCGCTGCTGCGCGCGGTCCGTGAAG
CGGAAAAGGCACGCGTCGACGCCGGCCTGCCGCGCGGCTATCTGCCGATCGACGGCATCGCGGCGTACGACGCGGCCGTG
CAGAAGCTGCTGCTCGGCAACGATTCGCCGCTGATCGCCGCGGGCCGCGTGGTCACCGCGCAGGCGCTGGGCGGCACGGG
CGCACTGAAGATCGGCGCCGATTTCCTGCGCACCGTGAACCCGAACGTGAAGGTCGCGATCAGCGATCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAAGCAGCCGGTTTCGAGGTCGTCGCGTATCCGTACTACGACGCGGCCACCAACGGCGTGAAC
TTCGAAGGCATGCTGTCGGCGCTGAACGGCTATGCGCCGGGCACGATCGTCGTGCTGCACGCGTGCTGCCACAACCCGAC
CGGCGTGGACCTGACCGAAGCGCAATGGCAGCAGGTCGTCGACGTCGTCAAGGCGCGCAACCTCGTGCCGTTCCTCGACA
TCGCGTATCAGGGCTTCGGCGAAAGCATCGAGGCCGATGCCGCGGCCGTGCGTCTGTTCGCGGCAACCGATCTGAACGCG
TTCGTCTCGTCGTCGTTCTCGAAGTCGTTCTCGCTGTACGGCGAGCGCGTCGGCGCGCTGTCGATCATCACGTCGAGCAA
GGACGAAGCCGCGCGCGTGCTGTCGCAGCTCAAGCGCGTGATCCGCACGAACTACTCGAACCCGCCGACGCATGGCGGTG
CCGTGGTTGCTGCAGTGCTCGCGTCGCCGGAACTGCACGCTGCGTGGGTGCAGGAACTCGGCGAAATGCGCGATCGCATC
CGCGCGATGCGCAACGGTCTCGTCGAGCGCCTGAAGGCGAGCGGCGTCGATCGCGACTTCAGCTTCATCAACGCACAGCG
CGGGATGTTCTCGTATTCGGGTCTGACCGCCGCGCAAGTCGATCGTCTGCGCGAAGAGTTCGGCATTTACGCCGTCGCAA
CGGGCCGGATCTGCGTCGCGGCGCTGAACACGCGTAACCTCGACGTCGTCGCGAATGCCGTCGCGGCCGTGCTGAAGTAA

Upstream 100 bases:

>100_bases
GCTGCTGCGCTTCCCGGCGTCGTGCCTGCCCATGCGGGCGCTGCAGCGTCCGCCTTGCCGGTTGAAAGCCTGACCCTCTT
TTTACTACTGCCGAATCATC

Downstream 100 bases:

>100_bases
AGCGGCAGCGCGGCAGCGGTCGTCGCTGCCCGCCGCTCGGCCGAAACGAAAAACGCGCTCTCCGGAGCGCGTTTTTTTAT
GCCATTCGCTGTCACGTGCG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLFSAVQLAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEDGKIPLLRAVREAEKARVDAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FEGMLSALNGYAPGTIVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDIAYQGFGESIEADAAAVRLFAATDLNA
FVSSSFSKSFSLYGERVGALSIITSSKDEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHAAWVQELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQVDRLREEFGIYAVATGRICVAALNTRNLDVVANAVAAVLK

Sequences:

>Translated_399_residues
MSLFSAVQLAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEDGKIPLLRAVREAEKARVDAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FEGMLSALNGYAPGTIVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDIAYQGFGESIEADAAAVRLFAATDLNA
FVSSSFSKSFSLYGERVGALSIITSSKDEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHAAWVQELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQVDRLREEFGIYAVATGRICVAALNTRNLDVVANAVAAVLK
>Mature_398_residues
SLFSAVQLAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEDGKIPLLRAVREAEKARVDAGLPRGYLPIDGIAAYDAAVQ
KLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNF
EGMLSALNGYAPGTIVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDIAYQGFGESIEADAAAVRLFAATDLNAF
VSSSFSKSFSLYGERVGALSIITSSKDEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHAAWVQELGEMRDRIR
AMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQVDRLREEFGIYAVATGRICVAALNTRNLDVVANAVAAVLK

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=43.7185929648241, Blast_Score=342, Evalue=5e-94,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=43.640897755611, Blast_Score=328, Evalue=5e-90,
Organism=Homo sapiens, GI117414139, Length=399, Percent_Identity=27.3182957393484, Blast_Score=169, Evalue=4e-42,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=55.3884711779449, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.4747474747475, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=42, Blast_Score=346, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=42.3558897243108, Blast_Score=335, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=40.0497512437811, Blast_Score=303, Evalue=9e-83,
Organism=Caenorhabditis elegans, GI17569537, Length=398, Percent_Identity=33.9195979899498, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=41.3145539906103, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17550384, Length=269, Percent_Identity=33.8289962825279, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=38.8206388206388, Blast_Score=299, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6322743, Length=436, Percent_Identity=32.1100917431193, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24580972, Length=400, Percent_Identity=42.75, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24580970, Length=400, Percent_Identity=42.75, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI19920542, Length=393, Percent_Identity=42.4936386768448, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI19922362, Length=402, Percent_Identity=40.547263681592, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24654046, Length=402, Percent_Identity=40.547263681592, Blast_Score=308, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42583; Mature: 42452

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVQLAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEDGKIPLLRAVREAEKARVD
CCHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHCHHHHHHCC
PNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFEGMLSALNGYAPGTIVVLH
CCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHEEEE
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDIAYQGFGESIEADAAAVRLFAATDLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHEEEEECCCHHH
FVSSSFSKSFSLYGERVGALSIITSSKDEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHAAWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCHHHHH
DRLREEFGIYAVATGRICVAALNTRNLDVVANAVAAVLK
HHHHHHHCEEEEEECCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFSAVQLAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEDGKIPLLRAVREAEKARVD
CHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHCHHHHHHCC
PNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFEGMLSALNGYAPGTIVVLH
CCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHEEEE
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDIAYQGFGESIEADAAAVRLFAATDLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHEEEEECCCHHH
FVSSSFSKSFSLYGERVGALSIITSSKDEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHAAWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCHHHHH
DRLREEFGIYAVATGRICVAALNTRNLDVVANAVAAVLK
HHHHHHHCEEEEEECCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]