Click here to switch to the map view.

The map label for this gene is nuoH [H]

Identifier: 161524211

GI number: 161524211

Start: 1131822

End: 1132889

Strand: Direct

Name: nuoH [H]

Synonym: Bmul_1035

Alternate gene names: 161524211

Gene position: 1131822-1132889 (Clockwise)

Preceding gene: 161524210

Following gene: 161524212

Centisome position: 32.82

GC content: 64.14

Gene sequence:

>1068_bases
ATGAGCTTGTTCGATACGATCAACGCGGGCGGAGCCCAGCTTCTCGGCGTCGCATGGCCGACGGTGTGGGCGCTCGTGCG
CATCCTCGTCGTCGCCGTCGTGATCCTGCTGTGCGTCGCGTACCTGATTCTGTGGGAGCGCAAGCTGATCGGCTGGATGC
ACGTGCGTCTCGGCCCGAACCGCGTCGGCCCGGCCGGCCTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTGAAG
GAAGTGATTCAGCCGACCGCCGCGAGCCGCTGGCTGTACCTGATCGCGCCGATCATGACCGTCGTGCCGGCGTTCGCGGT
GTGGGCGGTGATCCCGTTCCAGGCCGAAGCGGTGCTCGCGAACGTGAACGCGGGCCTGCTCTACGCGATGGCGATCTCGT
CGATCGGCGTGTACGCGGTGATTCTCGCCGGCTGGGCGTCGAACTCGAAGTACGCGTTCCTCGGCGCGATGCGCGCCGCG
GCGCAGATGGTGTCGTACGAAATCTCGATGGGCTTCGCGCTCGTGCTCGTGCTGATGACGGCCGGCAGCCTGAACCTGTC
GGAAATCGTCAATTCGCAGCAGCACGGCTTCTTCGCCGGCCACGGCGTGAACTTCCTGTCGTGGAACTGGCTGCCGCTGC
TGCCGGCCTTCGTCGTCTACTTCATCTCGGGCATCGCCGAAACGAACCGTCACCCGTTCGACGTGGTGGAAGGGGAGTCG
GAAATCGTCGCGGGTCACATGATCGACTACTCGGGCATGGCGTTCGCGCTGTTCTTCCTCGCCGAGTACATCAACATGAT
CGTGATCTCGGCACTGGCCGCGACGCTGTTCCTCGGCGGCTGGGACGCACCGTTCGAATTCCTGTCGTTCATCCCGGGCA
TCTTCTGGCTGGTGCTGAAGGTATTCGCGCTGCTGTCGGTGTTCATCTGGGTGCGCGCGACGTTCCCGCGCTTCCGTTAC
GACCAGATCATGCGCCTCGGCTGGAAGGTGTTCCTGCCCGTCACGGTGATCTGGGTGGTCGTGGTCGGCTTCTGGATGAT
GTCGCCGCTCAACATCTGGGTGAAGTAA

Upstream 100 bases:

>100_bases
CGCGAATCTTGCGGAGACGGTCGTTCGCGTGTCGGCGGCGACGCCTGCCGGCGCAGCGCTCGGCAGCCTGTCCGGTGAAC
TGGTGGTGGAGAAGGCGTAA

Downstream 100 bases:

>100_bases
TCGGACGAAATCATGACGGCAATCCAACACTTCTTTAAGACCTTCTTCCTGACCGAACTGCTGAAGGGGCTCGCGCTGAC
CGGCCGTTACACGTTCCGGC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSLFDTINAGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLK
EVIQPTAASRWLYLIAPIMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVNSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRFRY
DQIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK

Sequences:

>Translated_355_residues
MSLFDTINAGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLK
EVIQPTAASRWLYLIAPIMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVNSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRFRY
DQIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK
>Mature_354_residues
SLFDTINAGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLKE
VIQPTAASRWLYLIAPIMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAA
QMVSYEISMGFALVLVLMTAGSLNLSEIVNSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGESE
IVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRFRYD
QIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=302, Percent_Identity=43.3774834437086, Blast_Score=256, Evalue=3e-68,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=41.0658307210031, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1789077, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39292; Mature: 39161

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFDTINAGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPAGLLQPIADVLKLLLKEVIQPTAASRWLYLIAPIMTVVPAFAVWAVIPFQAEAVLA
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVNSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFALLSVFIWVRATFPRFRYDQIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
SLFDTINAGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPAGLLQPIADVLKLLLKEVIQPTAASRWLYLIAPIMTVVPAFAVWAVIPFQAEAVLA
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVNSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFALLSVFIWVRATFPRFRYDQIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA