BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence.
Accession	NC_010084
Length	3,448,466

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The map label for this gene is fabG [H]

Identifier: 161524162

GI number: 161524162

Start: 1080038

End: 1080874

Strand: Direct

Name: fabG [H]

Synonym: Bmul_0986

Alternate gene names: 161524162

Gene position: 1080038-1080874 (Clockwise)

Preceding gene: 161524148

Following gene: 161524163

Centisome position: 31.32

GC content: 70.85

Gene sequence:

>837_bases
ATGCGCGGCGCGACGGAATCCGCGCCGGCGCGCGTCGCAACCCTGGGGAAATCGACGATGGATCTCGGCATCGAAGGAAA
GACCGCGCTCGTCTGCGCGGCGAGTAAGGGACTCGGGCGCGGCTGCGCGCAGGCGCTGGCCGCCGAAGGCGTGAATCTCG
TGATCGTCGCGCGCACGCGCGCGACGCTCGAGGAAACCGCGGAGGAAATTCGCGCGGCATCGAACGTGTCGGTCACGGCC
GTCGCGTGCGACATCACGACGCCCGAGGGCCGCGCGGCCGCGCTGGCCGCGTGCCCGCAGCCCGACATTCTCGTGACGAA
TGCGGGCGGCCCGCCGCCCGGCGATTTCCGCGATTTCTCGCACGACGACTGGATCCGCGCGCTCGAAGCGAACATGCTCA
CGCCGATCGAGCTGATCCGCGCGACCGTCGACGGCATGATCGCGCGACGCTTCGGCCGCATCGTCAACATCACGAGCTCG
GCCGTGAAGGCGCCGATCGACGTGCTGGCGCTGTCGAACGGCGCGCGCTCGGGGCTGACGGGCTTCGTCGCCGGGCTCGC
GCGCAAGGTCGCGCCGCACGGCGTGACGATCAACAACCTGCTGCCGGGGTTGTTCGATACCGACCGCATCGCGACGACGC
TCGCGGCGGCCGCGAAGGCGCAAGGCGTGACGGTCGACGAACTGCGCGCGCGGCGCGCGAAGGAAATCCCGGCCGGCCGT
CTCGGCACGCGCGAAGAGTTCGGCGCCGCCTGCGCGTTCCTCTGCAGCGTGCATGCCGCATATATCACCGGCCAGAACTG
GCTGCTCGACGGCGGCGCGTACCCCGGCACGTTCTGA

Upstream 100 bases:

>100_bases
TCGCGCGCGCATGGTCGCAATTTTACCAAGGCGCGCCGCGCGATCCGGATATTATCGACGTCTCACGACAACCCGCGCGC
CGCGCGCGTCCGTGCGGCCG

Downstream 100 bases:

>100_bases
CACCGCGCACGCCAGGCGCATGCCGTACCGTCAACGACAATCACAACCCTGAAGGACGAAGGATCTGGAGATGAGCAAAC
CCCGCATCGCACTGATTGCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MRGATESAPARVATLGKSTMDLGIEGKTALVCAASKGLGRGCAQALAAEGVNLVIVARTRATLEETAEEIRAASNVSVTA
VACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALEANMLTPIELIRATVDGMIARRFGRIVNITSS
AVKAPIDVLALSNGARSGLTGFVAGLARKVAPHGVTINNLLPGLFDTDRIATTLAAAAKAQGVTVDELRARRAKEIPAGR
LGTREEFGAACAFLCSVHAAYITGQNWLLDGGAYPGTF

Sequences:

>Translated_278_residues
MRGATESAPARVATLGKSTMDLGIEGKTALVCAASKGLGRGCAQALAAEGVNLVIVARTRATLEETAEEIRAASNVSVTA
VACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALEANMLTPIELIRATVDGMIARRFGRIVNITSS
AVKAPIDVLALSNGARSGLTGFVAGLARKVAPHGVTINNLLPGLFDTDRIATTLAAAAKAQGVTVDELRARRAKEIPAGR
LGTREEFGAACAFLCSVHAAYITGQNWLLDGGAYPGTF
>Mature_278_residues
MRGATESAPARVATLGKSTMDLGIEGKTALVCAASKGLGRGCAQALAAEGVNLVIVARTRATLEETAEEIRAASNVSVTA
VACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALEANMLTPIELIRATVDGMIARRFGRIVNITSS
AVKAPIDVLALSNGARSGLTGFVAGLARKVAPHGVTINNLLPGLFDTDRIATTLAAAAKAQGVTVDELRARRAKEIPAGR
LGTREEFGAACAFLCSVHAAYITGQNWLLDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=267, Percent_Identity=29.2134831460674, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=26.530612244898, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=27.4436090225564, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=27.34375, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI226371731, Length=184, Percent_Identity=27.7173913043478, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=26.4, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=28.3422459893048, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI66933014, Length=173, Percent_Identity=27.1676300578035, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI126723750, Length=270, Percent_Identity=26.2962962962963, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705855, Length=200, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=27.4809160305344, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=34.0909090909091, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=32.9457364341085, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=28.1954887218045, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=30.3846153846154, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=30.2788844621514, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=23.046875, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=25.1937984496124, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.0700389105058, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=26.0869565217391, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=29.277566539924, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=27.734375, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.0380228136882, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=29.3436293436293, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.1375464684015, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=27.6515151515151, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.4436090225564, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=28.4615384615385, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.5171102661597, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=28.4615384615385, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.9961977186312, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.1746031746032, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=270, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=26.8482490272374, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=28.2442748091603, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=27.9850746268657, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=26.3565891472868, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=209, Percent_Identity=28.7081339712919, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=24.6031746031746, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=27.3809523809524, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.2252964426877, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=26.9961977186312, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=30.7392996108949, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28690; Mature: 28690

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGATESAPARVATLGKSTMDLGIEGKTALVCAASKGLGRGCAQALAAEGVNLVIVARTR
CCCCCCCCCHHHHHHCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCH
ATLEETAEEIRAASNVSVTAVACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFS
HHHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCC
HDDWIRALEANMLTPIELIRATVDGMIARRFGRIVNITSSAVKAPIDVLALSNGARSGLT
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECHHHHHCCHHEEEECCCCCCCHH
GFVAGLARKVAPHGVTINNLLPGLFDTDRIATTLAAAAKAQGVTVDELRARRAKEIPAGR
HHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
LGTREEFGAACAFLCSVHAAYITGQNWLLDGGAYPGTF
CCCHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MRGATESAPARVATLGKSTMDLGIEGKTALVCAASKGLGRGCAQALAAEGVNLVIVARTR
CCCCCCCCCHHHHHHCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCH
ATLEETAEEIRAASNVSVTAVACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFS
HHHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCC
HDDWIRALEANMLTPIELIRATVDGMIARRFGRIVNITSSAVKAPIDVLALSNGARSGLT
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECHHHHHCCHHEEEECCCCCCCHH
GFVAGLARKVAPHGVTINNLLPGLFDTDRIATTLAAAAKAQGVTVDELRARRAKEIPAGR
HHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
LGTREEFGAACAFLCSVHAAYITGQNWLLDGGAYPGTF
CCCHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]