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The map label for this gene is eco [H]

Identifier: 161524082

GI number: 161524082

Start: 988382

End: 988879

Strand: Direct

Name: eco [H]

Synonym: Bmul_0903

Alternate gene names: 161524082

Gene position: 988382-988879 (Clockwise)

Preceding gene: 161524080

Following gene: 161524084

Centisome position: 28.66

GC content: 67.47

Gene sequence:

>498_bases
ATGAAATTCGCGATCCGGGCCGCGTTGGCCGCGTTCTGCGTGACGACTGCCGCGTGCGCGGCTGCGCCTGCGTCGGCGCC
GGCCGTCTCCGCCGAGTCGATCAAGATGTTTCCGCAACCGGCCGCCGGCCAGCAGCGCTTCGTGATCGCGCTGCCCGCGC
TCGAGAACGAAGGCGATGCGCGCGTCGAGCTGATGATCGGCAAGACGCTCGAGACCGACTGCAACCAGCACTGGTTCGGC
GGCGAGCTGACCGCCGAGGACGTGAAGGGGTGGGGCTATCCGTACTATCGGCTGACCGACGTGAAAGGGCCGGCAGCGAC
GATGATGGCCTGCCCCGGGCAGGCGCCGCAGCAGCGCTTCGTGCAGGTGCGTACCGACGGGCAACTGCTGCGCTACAACA
GCCGCTTGCCGCTCGTCGTGTATGTGCCGGACGGTTTCGACGTGCGCTATCGCGTATGGCACGCGTCAAAGGACGTTCAG
CAGGCAGTCGGCCGCTAA

Upstream 100 bases:

>100_bases
TGCCGGCTGTTCGCAATTGTGTCGCGAAATTACAGCGGCGTAAGGTGTTGCGGGGAAAGTGTTAGCATCCCGGGCTCTTT
TGTTTGCAAGGAGCACATCG

Downstream 100 bases:

>100_bases
CGCATTCGCCGGGCGCGGCGCCGCGCGATCACGACTGCGCGGGCAGCGCGGCGCCCGTGCCCGCGCCGGTCAGCGCCGGC
CATGCGGCCAGCGCGGCGTG

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKFAIRAALAAFCVTTAACAAAPASAPAVSAESIKMFPQPAAGQQRFVIALPALENEGDARVELMIGKTLETDCNQHWFG
GELTAEDVKGWGYPYYRLTDVKGPAATMMACPGQAPQQRFVQVRTDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQ
QAVGR

Sequences:

>Translated_165_residues
MKFAIRAALAAFCVTTAACAAAPASAPAVSAESIKMFPQPAAGQQRFVIALPALENEGDARVELMIGKTLETDCNQHWFG
GELTAEDVKGWGYPYYRLTDVKGPAATMMACPGQAPQQRFVQVRTDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQ
QAVGR
>Mature_165_residues
MKFAIRAALAAFCVTTAACAAAPASAPAVSAESIKMFPQPAAGQQRFVIALPALENEGDARVELMIGKTLETDCNQHWFG
GELTAEDVKGWGYPYYRLTDVKGPAATMMACPGQAPQQRFVQVRTDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQ
QAVGR

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=166, Percent_Identity=45.1807228915663, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 18022; Mature: 18022

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAIRAALAAFCVTTAACAAAPASAPAVSAESIKMFPQPAAGQQRFVIALPALENEGDA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCC
RVELMIGKTLETDCNQHWFGGELTAEDVKGWGYPYYRLTDVKGPAATMMACPGQAPQQRF
EEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHE
VQVRTDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQQAVGR
EEECCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MKFAIRAALAAFCVTTAACAAAPASAPAVSAESIKMFPQPAAGQQRFVIALPALENEGDA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCC
RVELMIGKTLETDCNQHWFGGELTAEDVKGWGYPYYRLTDVKGPAATMMACPGQAPQQRF
EEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHE
VQVRTDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQQAVGR
EEECCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA