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The map label for this gene is otsA [H]

Identifier: 161524076

GI number: 161524076

Start: 983285

End: 984706

Strand: Direct

Name: otsA [H]

Synonym: Bmul_0897

Alternate gene names: 161524076

Gene position: 983285-984706 (Clockwise)

Preceding gene: 161524075

Following gene: 161524077

Centisome position: 28.51

GC content: 67.3

Gene sequence:

>1422_bases
ATGAGCAGATTGATCGTGGTATCGAACCGTGTCGCCATCGGCGAGGACACACGCCCGAGCGCGGGCGGCCTCGCGGTCGG
CGTGATGGACGCGCTGCAGGAAACGGGCGGCGTCTGGTTCGGCTGGAACGGCGAGATCGTGGGGACGCCGGACGCGGCGC
CGGCGATCCGGCGCGACGGCAACGTGACTTATGCGACGGTCGGACTGACGCGCCGCGACTACGATCAGTACTATCGCGGG
TTTTCGAACGCGACGCTGTGGCCCGTGTTCCACTATCGCGGCGATCTCGCGCGCTTCGACCGACAGGAGTACGCCGGCTA
TCTGCGCGTGAACGCGATGCTCGCGAAGCAGCTCGCCGCACTGCTGCGCCCGGACGATCTGATCTGGGTGCACGACTACC
ATCTGCTGCCGTTCGCGCACGCGCTGCGCGAGCTCGGCGTGAAGAATCCGATCGGCTTCTTCCTGCACATTCCGTTTCCG
TCGCCGGACGTGCTGCGGCTCGTGCCGCCGCACGACGAACTCGTGAAGTTCATGTGCGCGTATGACGTGACGGGCTTCCA
GACCGATGCCGACAGGCAGGCGTTCACCGACTACATCGAGCGGCGCGGGATCGGCACCGCAAGCGAGGACGGCATGCTGC
ACGCACACGGCCGCGTCGTGAAGGTGGCCGCGTATCCGATCGGCGTGTATCCGGATGCGATCGCGCAGGCGGCCGTCCAG
TACGGCGCGCGCAAGCCGGTGAAGATGCTGCGCGACGCACTGGGCGGCCGCAAGCTCGTGATGAGCGTCGATCGTCTCGA
CTATTCGAAGGGGCTCGTCGAACGCTTCCAGGCGTTCGAGCGCATGCTCGCGAATGCGCCGGGCTGGCAGGGGCGCGTGT
CGCTCGTGCAGATCGCGCCGCCGACGCGTTCCGACGTGCAGACGTACCAGCGAATCCGCGAAACGCTCGAAGGCGAGGCC
GGCCGCATCAACGGACGGTTTTCGCAGCTCGACTGGACGCCGATTCAATATCTGAACCGCAAGTACGAGCGCAATCTGCT
GATGGCGTTCTTCCGCATGTCGCAGGTCGGCTACGTGACGCCGCTGCGCGACGGGATGAACCTCGTCGCGAAGGAATACG
TCGCGTCGCAGGATCCGGCCGATCCGGGCGTGCTCGTGCTGTCCGAATTTGCGGGCGCCGCGGCGGAGCTGACGGGCGCG
CTGCTCGTCAATCCGTATGACCTCTCGCAGATGGCCGACGCGCTCGAGCGTGCACTTTCGATGCCGCTCGCGGAACGGCA
GGCGCGTCACGAGGAGAACCTCGCGCGGCTGCGCGCGAACGACCTGTCGGTGTGGCGCGATACGTTCGTCGCCGATCTGC
GCAGCGTCGCGGCGGCGGCCTCGGTCACGCAGCGCGCGGGCCGACGCATCGCGCATGCGTGA

Upstream 100 bases:

>100_bases
TCTCTGACGTCTGAACCGCCGCGCGGCAGCGTTTGCGCCGCCGCGCCCGTCATGGCGTGCGCCGCACGCCATTCAATCGA
AATCGAGGAGGGGAAGCCGA

Downstream 100 bases:

>100_bases
GCGCGCGAGCGCGTCCGGCGCCGCCCGGTGCGCGCCGGACGACGATGCGCTCGATCGGTTTTTCGTCGTCACGGGCGGCC
CCGGTTCGGGCAAGAGCACT

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTPDAAPAIRRDGNVTYATVGLTRRDYDQYYRG
FSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHALRELGVKNPIGFFLHIPFP
SPDVLRLVPPHDELVKFMCAYDVTGFQTDADRQAFTDYIERRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQ
YGARKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTRSDVQTYQRIRETLEGEA
GRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGA
LLVNPYDLSQMADALERALSMPLAERQARHEENLARLRANDLSVWRDTFVADLRSVAAAASVTQRAGRRIAHA

Sequences:

>Translated_473_residues
MSRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTPDAAPAIRRDGNVTYATVGLTRRDYDQYYRG
FSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHALRELGVKNPIGFFLHIPFP
SPDVLRLVPPHDELVKFMCAYDVTGFQTDADRQAFTDYIERRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQ
YGARKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTRSDVQTYQRIRETLEGEA
GRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGA
LLVNPYDLSQMADALERALSMPLAERQARHEENLARLRANDLSVWRDTFVADLRSVAAAASVTQRAGRRIAHA
>Mature_472_residues
SRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTPDAAPAIRRDGNVTYATVGLTRRDYDQYYRGF
SNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHALRELGVKNPIGFFLHIPFPS
PDVLRLVPPHDELVKFMCAYDVTGFQTDADRQAFTDYIERRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQY
GARKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTRSDVQTYQRIRETLEGEAG
RINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGAL
LVNPYDLSQMADALERALSMPLAERQARHEENLARLRANDLSVWRDTFVADLRSVAAAASVTQRAGRRIAHA

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=466, Percent_Identity=53.0042918454936, Blast_Score=490, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI115533558, Length=420, Percent_Identity=29.7619047619048, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI115533560, Length=420, Percent_Identity=29.7619047619048, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71987012, Length=429, Percent_Identity=29.6037296037296, Blast_Score=158, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6319602, Length=469, Percent_Identity=34.9680170575693, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6320279, Length=420, Percent_Identity=27.1428571428571, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323537, Length=386, Percent_Identity=27.720207253886, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323917, Length=373, Percent_Identity=26.5415549597855, Blast_Score=163, Evalue=7e-41,
Organism=Drosophila melanogaster, GI19920676, Length=497, Percent_Identity=36.2173038229376, Blast_Score=285, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52698; Mature: 52567

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTPDAAPAIRRDG
CCCEEEEECCEEECCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEECCCCCCHHHCCC
NVTYATVGLTRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAA
CEEEEEECCCHHHHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LLRPDDLIWVHDYHLLPFAHALRELGVKNPIGFFLHIPFPSPDVLRLVPPHDELVKFMCA
HHCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHH
YDVTGFQTDADRQAFTDYIERRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQ
HCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHH
YGARKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAP
HCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
PTRSDVQTYQRIRETLEGEAGRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGALLVNPYDLSQMADALERALS
CCHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHCCEEEECCCCHHHHHHHHHHHHC
MPLAERQARHEENLARLRANDLSVWRDTFVADLRSVAAAASVTQRAGRRIAHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTPDAAPAIRRDG
CCEEEEECCEEECCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEECCCCCCHHHCCC
NVTYATVGLTRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAA
CEEEEEECCCHHHHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LLRPDDLIWVHDYHLLPFAHALRELGVKNPIGFFLHIPFPSPDVLRLVPPHDELVKFMCA
HHCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHH
YDVTGFQTDADRQAFTDYIERRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQ
HCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHH
YGARKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAP
HCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
PTRSDVQTYQRIRETLEGEAGRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGALLVNPYDLSQMADALERALS
CCHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHCCEEEECCCCHHHHHHHHHHHHC
MPLAERQARHEENLARLRANDLSVWRDTFVADLRSVAAAASVTQRAGRRIAHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA