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The map label for this gene is cysH1 [H]

Identifier: 161524000

GI number: 161524000

Start: 898284

End: 899027

Strand: Direct

Name: cysH1 [H]

Synonym: Bmul_0821

Alternate gene names: 161524000

Gene position: 898284-899027 (Clockwise)

Preceding gene: 161523999

Following gene: 161524001

Centisome position: 26.05

GC content: 67.61

Gene sequence:

>744_bases
ATGAGCAACGCAACCGCCACCGCGCTGACGCCCGAGCTCGCCGCGAAGGTCGAGCGGCTCGACGCGCTGCTCGCGCAGAT
CGCCGCGCGTCATCCGAACGTGAAGCTCGCGAGCAGCCTCGCGGCGGAAGACATGTTGCTCACGCACGCGATCCTGTCGA
AGGGTCTCGCGATCGGCATCTTCTCGCTGAACACGGGCCGCTTGCATGCCGAGACGCTCGGCATGATCGACCGCGTGCGG
GAGCGCTACGGCTACGAGATCGAGCAGTTCCACCCGCAGCAGGATGCGGTCGATCGCTATGTCGCCGAGCATGGACTGAA
CGCGTTCTACGAAAGCGTCGAGCTCCGAAAATCGTGCTGCCACATCCGCAAGGTCGAGCCGCTGAACCGCGCGCTCGCCG
ACGTCGATGCGTGGGTCACGGGCCAGCGCCGCGAGCAGTCGGTCACGCGTGCCGAGCTGCACGAGGAAGAGCAGGACGAG
GCGCGCGGGATCGCGAAGTACAATCCGCTCGCCGACTGGACCGAGCGCGACGTGTGGGCGTACCTCGACGCGTTCGACGT
GCCGGTCAATCCGCTGCATGCGCGCGGCTATCCGAGCATCGGCTGCGAGCCGTGTACGCGTGCGATCCGTCCCGGCGAGG
ACAGCCGCGCGGGCCGCTGGTGGTGGGAGTCGCGCGACACGAAGGAATGCGGTCTGCACATCGCGATCACGCCGATTCCC
GCAAGCGCCGACGCATCGCACTGA

Upstream 100 bases:

>100_bases
TCACGCAGCGCTATCAGGGCGCGTTCGACGAGCCGGCGCCGCTGTTCCGTCGCCGCGCGGCGACGGCTGACGTGGCGACG
TCCGCTGCCAAGGTGAGCGC

Downstream 100 bases:

>100_bases
AGCACGAACGACAAGATCGAATATTGCGCCGCTCGCGACAGCGGGCGGCACGAACCCAGAAGAGAAGGACCGAAACCATG
AGCACGACGCTCGAGCAATC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSNATATALTPELAAKVERLDALLAQIAARHPNVKLASSLAAEDMLLTHAILSKGLAIGIFSLNTGRLHAETLGMIDRVR
ERYGYEIEQFHPQQDAVDRYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVDAWVTGQRREQSVTRAELHEEEQDE
ARGIAKYNPLADWTERDVWAYLDAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHIAITPIP
ASADASH

Sequences:

>Translated_247_residues
MSNATATALTPELAAKVERLDALLAQIAARHPNVKLASSLAAEDMLLTHAILSKGLAIGIFSLNTGRLHAETLGMIDRVR
ERYGYEIEQFHPQQDAVDRYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVDAWVTGQRREQSVTRAELHEEEQDE
ARGIAKYNPLADWTERDVWAYLDAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHIAITPIP
ASADASH
>Mature_246_residues
SNATATALTPELAAKVERLDALLAQIAARHPNVKLASSLAAEDMLLTHAILSKGLAIGIFSLNTGRLHAETLGMIDRVRE
RYGYEIEQFHPQQDAVDRYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVDAWVTGQRREQSVTRAELHEEEQDEA
RGIAKYNPLADWTERDVWAYLDAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHIAITPIPA
SADASH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=228, Percent_Identity=31.140350877193, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325425, Length=117, Percent_Identity=43.5897435897436, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27618; Mature: 27487

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNATATALTPELAAKVERLDALLAQIAARHPNVKLASSLAAEDMLLTHAILSKGLAIGI
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLGMIDRVRERYGYEIEQFHPQQDAVDRYVAEHGLNAFYESVELRKSCC
EECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIRKVEPLNRALADVDAWVTGQRREQSVTRAELHEEEQDEARGIAKYNPLADWTERDVWA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
YLDAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHIAITPIP
HHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCC
ASADASH
CCCCCCC
>Mature Secondary Structure 
SNATATALTPELAAKVERLDALLAQIAARHPNVKLASSLAAEDMLLTHAILSKGLAIGI
CCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLGMIDRVRERYGYEIEQFHPQQDAVDRYVAEHGLNAFYESVELRKSCC
EECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIRKVEPLNRALADVDAWVTGQRREQSVTRAELHEEEQDEARGIAKYNPLADWTERDVWA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
YLDAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHIAITPIP
HHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCC
ASADASH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]