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The map label for this gene is ytnA [H]

Identifier: 161523958

GI number: 161523958

Start: 855152

End: 856531

Strand: Direct

Name: ytnA [H]

Synonym: Bmul_0778

Alternate gene names: 161523958

Gene position: 855152-856531 (Clockwise)

Preceding gene: 161523957

Following gene: 161523959

Centisome position: 24.8

GC content: 66.59

Gene sequence:

>1380_bases
GTGACACGACAACAGCAGTCGTTCGACACCATCGTCGAACGCGAACAGGGGCTGCGCCACGCGCTGACGTCGGGGCAGAT
GGCGATGATCGCGATCGGCGGCGCGATCGGCACGGGACTCTTTCTCGGCAGCGGTTTCGCGATCGGGCTCGCCGGCCCGA
GCGTGCTCGTGTCCTATGCGATCGGCGCGCTGATCGCATTGCTGCTGATGGGCGCGCTGGCCGAAATGACGGTCGCGCAT
CCGACGGCCGGCTCGTTCGGCGCGTATGCCGAACATTACGTCGGCCCGCTCGCCGGCTTTCTGGTCCGTTACGCGTACTG
GTTCGCGGTCGTATTCGCGATCGGTACCGAGATCAGCGCGATCGCCGTGTTCATGAAGTACTGGTTTCCGGCGGTGCCGG
GCTGGTACTGGGTCATCGGCTTCTCCGCGCTGCTGATCGCGGTGAATCTCGCGAGCGTCACGCTGTACGGTTCGGTCGAA
TATGCGTTCTCGCTGCTGAAGATCGCGGCGATCGTCGTCTTCATCGTGCTCGGCGCGTATCTCGTGTGGTCCGCGCCGCC
CGCATCCGGCATCGGCTTCGCGAACTACACCGCGCACGGCGGTTTCATGCCGAAAGGGCCGTGGGGCACCTGGGTCGCGG
TGATCGTCGCGATCTTCAGCTACATGAGCATCGAGGCGGTCGCGATCGCGGCCGGCGAAGCGCGCGATCCGCAGCACGCG
GTCACGCGCGCGTTCCGCTCGACCGTGTTTCGCCTCGTGCTGTTCTATCTGCTGACGCTGTCGCTGATGCTCGCGATCGT
CCCGTGGACGCAGGCCGGCACCGACGAGAGCCCGTTCGTGAAGGTCATGGCCGCGACGCACGTGCCGTACGCGGCCGGCG
TGATCAACTTCGTGGTGCTGATCGCCGCGTTGTCCGCGATGAACAGCCAGCTGTACGTGACGACGCGGATGATGTTCAGC
CTGTCGCGCGCGCGTCTCGCGCCCGCGGTGTTCGGCCGGCTGGGCGCGAACGGCGTGCCGCGCGCGGCACTCTGGATCTC
GACGAGCGGCGTCGCCGTCGCGGCCGTGCTGGTTGCGGTGTCGCCCGATACGGCGTTTACCGTGATGATGGCGATCGCGA
TGTTCGGCGCGCTGTTCACCTGGCTGATGATCTTCGTCACGCATCTGCGTTTTCGTGCGCGCTACCGCGGCCCGGCGCTC
GCATTCCGCATGTGGGGCCATCCGGTCGGCAGTCTGCTTGGGGCCGCGCTCGTCGCGTCGATCCTGCTGACGACGGCATT
CACGCACGAATTCCGCATGACGATGGCGGTCGGCGTCGCGTTCGTCGTGCTGCTGGTGGGCGCGTATGTGCTGCATTACC
GGCACGAACACGCCCGCTGA

Upstream 100 bases:

>100_bases
ATAATTGCGGGTTCATCCGAACGGCGCGGGAAGTTCTCCGCGCCGTTTCGTTTTATCCGGCGCCGGCGGCGCGTTCGTAG
GGCAGGGGAGTGGCAACGCA

Downstream 100 bases:

>100_bases
GGCCGCGGCGGTGCGCCGCGCGATACGGCGCCGGCACGCGGCATCGCCTGTCCGTCAAATGCTAAGGTTGCGTTAAGCCG
TCGGCGATTACATTCGAGCC

Product: amino acid permease-associated protein

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MTRQQQSFDTIVEREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMGALAEMTVAH
PTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGSVE
YAFSLLKIAAIVVFIVLGAYLVWSAPPASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAAGEARDPQHA
VTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVVLIAALSAMNSQLYVTTRMMFS
LSRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVAVSPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRARYRGPAL
AFRMWGHPVGSLLGAALVASILLTTAFTHEFRMTMAVGVAFVVLLVGAYVLHYRHEHAR

Sequences:

>Translated_459_residues
MTRQQQSFDTIVEREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMGALAEMTVAH
PTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGSVE
YAFSLLKIAAIVVFIVLGAYLVWSAPPASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAAGEARDPQHA
VTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVVLIAALSAMNSQLYVTTRMMFS
LSRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVAVSPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRARYRGPAL
AFRMWGHPVGSLLGAALVASILLTTAFTHEFRMTMAVGVAFVVLLVGAYVLHYRHEHAR
>Mature_458_residues
TRQQQSFDTIVEREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMGALAEMTVAHP
TAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGSVEY
AFSLLKIAAIVVFIVLGAYLVWSAPPASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAAGEARDPQHAV
TRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVVLIAALSAMNSQLYVTTRMMFSL
SRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVAVSPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRARYRGPALA
FRMWGHPVGSLLGAALVASILLTTAFTHEFRMTMAVGVAFVVLLVGAYVLHYRHEHAR

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=445, Percent_Identity=37.3033707865169, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI87081708, Length=449, Percent_Identity=36.7483296213808, Blast_Score=284, Evalue=8e-78,
Organism=Escherichia coli, GI1786602, Length=451, Percent_Identity=34.3680709534368, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1786302, Length=418, Percent_Identity=32.7751196172249, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI48994972, Length=454, Percent_Identity=33.0396475770925, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790653, Length=410, Percent_Identity=34.390243902439, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI87081915, Length=405, Percent_Identity=33.5802469135802, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1789017, Length=400, Percent_Identity=34, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1788480, Length=422, Percent_Identity=34.5971563981043, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI87081869, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320772, Length=455, Percent_Identity=29.2307692307692, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324061, Length=444, Percent_Identity=30.6306306306306, Blast_Score=180, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6324553, Length=393, Percent_Identity=31.8066157760814, Blast_Score=179, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6324059, Length=447, Percent_Identity=31.5436241610738, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324924, Length=455, Percent_Identity=27.6923076923077, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324990, Length=409, Percent_Identity=29.8288508557457, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322892, Length=433, Percent_Identity=30.2540415704388, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320717, Length=403, Percent_Identity=26.302729528536, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6321629, Length=415, Percent_Identity=25.7831325301205, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=429, Percent_Identity=28.4382284382284, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=397, Percent_Identity=26.9521410579345, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6319543, Length=399, Percent_Identity=27.3182957393484, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6319542, Length=415, Percent_Identity=26.5060240963855, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321053, Length=388, Percent_Identity=26.2886597938144, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6322967, Length=394, Percent_Identity=27.1573604060914, Blast_Score=126, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6319608, Length=442, Percent_Identity=24.8868778280543, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324981, Length=445, Percent_Identity=27.4157303370787, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320364, Length=458, Percent_Identity=22.2707423580786, Blast_Score=83, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49119; Mature: 48987

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQQQSFDTIVEREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYA
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCEEECCCHHHHHHHH
IGALIALLLMGALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
IAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGSVEYAFSLLKIAAIVVFIVLGAY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHH
LVWSAPPASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAAGEARDPQHA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHH
VTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
IAALSAMNSQLYVTTRMMFSLSRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVAV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHC
SPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRARYRGPALAFRMWGHPVGSLLGAALVAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHH
ILLTTAFTHEFRMTMAVGVAFVVLLVGAYVLHYRHEHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRQQQSFDTIVEREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYA
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCEEECCCHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]